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ONTOLOGY REPORT - ANNOTATIONS

Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201


show annotations for term's descendants           Sort by:
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (PMID:360074) RGD PMID:360074 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G ENSRNOG00000065410 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 Ensembl chr 2:178,497,468...178,499,169 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISO
ISS
IBA		 GO_REF:0000041
(PMID:10828945), (PMID:1881876)
GO_REF:0000024
GO_REF:0000033
(PMID:23704330)		 UniProt
RGD
GO_Central		 PMID:1881876 PMID:10828945 PMID:23704330 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IDA
IEA
IBA		 GO_REF:0000041
PMID:24733394
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:21163947 PMID:24733394 GO_REF:0000033 GO_REF:0000041, RGD:7244288, RGD:150521648 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEA
ISO
IBA		 GO_REF:0000041
UniProtKB:P53128 (PMID:10551815), (PMID:12673793), (PMID:25736335), (PMID:29891918)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:10551815 PMID:12673793 PMID:25736335 PMID:29891918 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO
IBA		 (PMID:12764149)
GO_REF:0000033		 RGD
GO_Central		 PMID:12764149 GO_REF:0000033 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IEA
ISO		 GO_REF:0000041
(PMID:24698160)
MGI:1277989 (PMID:19513116)		 UniProt
RGD		 PMID:19513116 PMID:24698160 GO_REF:0000041 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IEA
ISO		 GO_REF:0000041
MGI:98299 (PMID:19513116)		 UniProt
RGD		 PMID:19513116 GO_REF:0000041 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541)
(PMID:22057276)		 RGD PMID:15093541 PMID:22057276 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        small molecule metabolic process 1916
          one-carbon metabolic process 43
            tetrahydrofolate interconversion 13
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        modified amino acid metabolic process 190
          folic acid-containing compound metabolic process 25
            tetrahydrofolate metabolic process 19
              tetrahydrofolate interconversion 13
paths to the root