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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc



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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
JBrowse link
G Ahcyl2 adenosylhomocysteinase-like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:58,381,290...58,531,061
Ensembl chr 4:58,381,218...58,531,060
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Car1 carbonic anhydrase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car10 carbonic anhydrase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:78,055,875...78,556,490
Ensembl chr10:78,054,114...78,555,834
JBrowse link
G Car11 carbonic anhydrase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191
JBrowse link
G Car13 carbonic anhydrase 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
JBrowse link
G Car15 carbonic anhydrase 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:83,147,155...83,150,101
Ensembl chr11:83,147,146...83,150,101
JBrowse link
G Car2 carbonic anhydrase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car3 carbonic anhydrase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Car4 carbonic anhydrase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Car5a carbonic anhydrase 5A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
JBrowse link
G Car5b carbonic anhydrase 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Car6 carbonic anhydrase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
JBrowse link
G Car7 carbonic anhydrase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
JBrowse link
G Car8 carbonic anhydrase 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374
JBrowse link
G Car9 carbonic anhydrase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Gnmt glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3842652 (MGI:3842675|PMID:17937387)
RGD PMID:17937387 PMID:21873635 MGI:3842675, RGD:13792537 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Mat1a methionine adenosyltransferase 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Mat2a methionine adenosyltransferase 2A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mat2b methionine adenosyltransferase 2B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEP
ISO
(PMID:25633902) RGD PMID:25633902 PMID:14597174 RGD:1302361 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Sfxn1 sideroflexin 1 acts_upstream_of ISS
ISO
GO_REF:0000024
(PMID:30442778)
UniProt
RGD
PMID:30442778 GO_REF:0000024 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Sfxn3 sideroflexin 3 acts_upstream_of ISO
ISS
(PMID:30442778)
GO_REF:0000024
RGD
UniProt
PMID:30442778 GO_REF:0000024 NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO
IBA
(PMID:11516159), (PMID:29180469), (PMID:29364879), (PMID:29452640), (PMID:33015733)
PMID:21873635
RGD PMID:11516159 PMID:29180469 PMID:29364879 PMID:29452640 PMID:33015733 More... RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (MGI:67444|PMID:360074) RGD PMID:360074 MGI:67444 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISS
ISO
IBA
GO_REF:0000041
GO_REF:0000024
(PMID:10828945), (PMID:1881876)
(MGI:5503248|PMID:23704330)
PMID:21873635
UniProt
RGD
PMID:1881876 PMID:10828945 PMID:23704330 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:5503248, RGD:13792537 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IDA
IEA
IBA
PMID:24733394
GO_REF:0000041
PMID:21873635
UniProt
RGD
PMID:21163947 PMID:24733394 PMID:21873635 GO_REF:0000041, RGD:7244288, RGD:150521648, RGD:13792537 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEA
ISO
IBA
GO_REF:0000041
UniProtKB:P53128 (PMID:10551815), (PMID:12673793), (PMID:25736335), (PMID:29891918)
PMID:21873635
UniProt
RGD
PMID:10551815 PMID:12673793 PMID:25736335 PMID:29891918 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO
IBA
(PMID:12764149)
PMID:21873635
RGD PMID:12764149 PMID:21873635 RGD:13792537 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IEA
ISO
IBA
GO_REF:0000041
(PMID:24698160)
MGI:1277989 (MGI:3849912|PMID:19513116)
PMID:21873635
UniProt
RGD
PMID:19513116 PMID:24698160 PMID:21873635 GO_REF:0000041 MGI:3849912, RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
MGI:98299 (MGI:3849912|PMID:19513116)
UniProt
RGD
PMID:19513116 PMID:21873635 GO_REF:0000041 MGI:3849912, RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541)
(MGI:5300404|PMID:22057276)
RGD PMID:15093541 PMID:22057276 MGI:5300404 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      cellular metabolic process 9699
        one-carbon metabolic process 37
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 12
paths to the root