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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of toll-like receptor 4 signaling pathway
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Accession:GO:0034145 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms:exact_synonym: positive regulation of TLR4 signaling pathway;   positive regulation of toll-like receptor 4 signalling pathway



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positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:24380872)
UniProt
RGD
PMID:24380872 GO_REF:0000024 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) RGD PMID:18622013 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,381,010...86,389,952
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA
(PMID:11528597)
GO_REF:0000107
RGD
Ensembl
PMID:11528597 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Ninj1 ninjurin 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:25860173)
UniProt
RGD
PMID:25860173 GO_REF:0000024 NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA
(PMID:18511497)
GO_REF:0000107
RGD
Ensembl
PMID:18511497 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (PMID:19734906) RGD PMID:19734906 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)
RGD PMID:19412184 PMID:22685567 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IBA
(PMID:25736436)
GO_REF:0000033
RGD
GO_Central
PMID:25736436 GO_REF:0000033 NCBI chr 9:88,459,613...88,541,215
Ensembl chr 9:81,034,849...81,092,775
JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) RGD PMID:28593998 NCBI chr19:56,403,816...56,490,901
Ensembl chr19:39,496,527...39,580,969
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      signal transduction 7262
        positive regulation of signal transduction 1752
          positive regulation of pattern recognition receptor signaling pathway 85
            positive regulation of toll-like receptor 4 signaling pathway 14
Path 2
Term Annotations click to browse term
  biological_process 20553
    response to stimulus 11038
      response to external stimulus 2793
        response to external biotic stimulus 1888
          response to other organism 1872
            defense response to other organism 1330
              defense response to symbiont 1103
                innate immune response 1016
                  regulation of innate immune response 484
                    positive regulation of innate immune response 392
                      activation of innate immune response 322
                        innate immune response-activating signaling pathway 294
                          innate immune response activating cell surface receptor signaling pathway 91
                            cell surface pattern recognition receptor signaling pathway 79
                              cell surface toll-like receptor signaling pathway 73
                                toll-like receptor 4 signaling pathway 64
                                  regulation of toll-like receptor 4 signaling pathway 34
                                    positive regulation of toll-like receptor 4 signaling pathway 14
paths to the root