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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of toll-like receptor 4 signaling pathway
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Accession:GO:0034144 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms:exact_synonym: negative regulation of TLR4 signaling pathway;   negative regulation of toll-like receptor 4 signalling pathway



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negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IEA
IBA
(PMID:21900486)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:21900486 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19948740)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(MGI:4456928|PMID:20385881)
UniProt
RGD
PMID:20385881 GO_REF:0000024 MGI:4456928 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) RGD PMID:28609714 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA
(PMID:18511497)
GO_REF:0000107
RGD
Ensembl
PMID:18511497 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (MGI:3834524|PMID:17395780) RGD PMID:17395780 MGI:3834524 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) RGD PMID:31281713 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6152919|PMID:29407460), (MGI:6695864|PMID:31134514) RGD PMID:29407460 PMID:31134514 MGI:6152919 MGI:6695864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2822
      negative regulation of immune system process 565
        negative regulation of toll-like receptor 4 signaling pathway 17
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10511
      response to external stimulus 2701
        response to external biotic stimulus 1825
          response to other organism 1821
            defense response to other organism 1277
              defense response to symbiont 1142
                innate immune response 961
                  regulation of innate immune response 453
                    positive regulation of innate immune response 373
                      activation of innate immune response 302
                        innate immune response-activating signaling pathway 276
                          innate immune response activating cell surface receptor signaling pathway 90
                            cell surface pattern recognition receptor signaling pathway 77
                              cell surface toll-like receptor signaling pathway 72
                                toll-like receptor 4 signaling pathway 63
                                  regulation of toll-like receptor 4 signaling pathway 34
                                    negative regulation of toll-like receptor 4 signaling pathway 17
paths to the root