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ONTOLOGY REPORT - ANNOTATIONS


Term:ruffle membrane
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Accession:GO:0032587 term browser browse the term
Definition:The portion of the plasma membrane surrounding a ruffle.


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ruffle membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 located_in ISO (PMID:16908670) Alzheimers_University_of_Toronto PMID:16908670 NCBI chrNW_004624828:7,572,821...7,592,428
Ensembl chrNW_004624828:7,573,130...7,591,038
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 located_in ISO (PMID:14970227) BHF-UCL PMID:14970227 NCBI chrNW_004624969:212,089...254,532
Ensembl chrNW_004624969:212,321...253,328
JBrowse link
G Aif1 allograft inflammatory factor 1 located_in IEA
ISS
UniProt
TreeGrafter
GO_REF:0000024 GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624754:24,590,071...24,591,913
Ensembl chrNW_004624754:24,590,071...24,591,904
JBrowse link
G Aif1l allograft inflammatory factor 1 like located_in IEA UniProt
TreeGrafter
GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624760:4,739,886...4,757,291
Ensembl chrNW_004624760:4,739,793...4,757,280
JBrowse link
G Akt2 AKT serine/threonine kinase 2 located_in ISO (PMID:21907143) UniProt PMID:21907143 NCBI chrNW_004624925:262,590...322,440
Ensembl chrNW_004624925:273,881...326,984
JBrowse link
G Apc APC regulator of WNT signaling pathway located_in ISO (PMID:19151759) UniProt PMID:19151759 NCBI chrNW_004624743:30,517,034...30,635,740
Ensembl chrNW_004624743:30,546,323...30,635,737
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 located_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079
JBrowse link
G Arf4 ARF GTPase 4 located_in ISO (PMID:12446727) UniProt PMID:12446727 NCBI chrNW_004624821:346,579...362,021 JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624885:1,314,885...1,362,730
Ensembl chrNW_004624885:1,311,512...1,362,730
JBrowse link
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:17224451 RGD:2306207 NCBI chrNW_004624823:6,774,855...6,804,219 JBrowse link
G Bmx BMX non-receptor tyrosine kinase located_in ISO (PMID:11331870) UniProt PMID:11331870 NCBI chrNW_004624829:297,187...344,555
Ensembl chrNW_004624829:297,351...344,164
JBrowse link
G C2cd5 C2 calcium dependent domain containing 5 located_in ISO (PMID:21907143) UniProt PMID:21907143 NCBI chrNW_004624752:16,261,819...16,365,161
Ensembl chrNW_004624752:16,261,775...16,365,320
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone ISO RGD PMID:16335536 RGD:5131523 NCBI chrNW_004624828:2,523,761...2,533,387
Ensembl chrNW_004624828:2,521,272...2,535,475
JBrowse link
G Cdkl5 cyclin dependent kinase like 5 located_in ISO PMID:20861382 BHF-UCL PMID:20861382 RGD:8554575 NCBI chrNW_004624829:3,288,239...3,479,620
Ensembl chrNW_004624829:3,356,580...3,472,832
JBrowse link
G Cfl1 cofilin 1 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624767:20,574,884...20,578,413
Ensembl chrNW_004624767:20,574,966...20,579,796
JBrowse link
G Cib1 calcium and integrin binding 1 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624768:17,209,639...17,212,996
Ensembl chrNW_004624768:17,209,639...17,213,114
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 located_in ISO (PMID:20937854)
MMO:0000686
UniProt
RGD
PMID:20937854 PMID:22992739 RGD:28912745 NCBI chrNW_004624788:11,441,840...11,657,515
Ensembl chrNW_004624788:11,441,747...11,573,029
JBrowse link
G Diaph1 diaphanous related formin 1 located_in ISO (PMID:9214622) MGI PMID:9214622 NCBI chrNW_004624774:738,717...845,187
Ensembl chrNW_004624774:739,206...845,272
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chrNW_004624839:3,495,580...3,899,009
Ensembl chrNW_004624839:3,509,441...3,899,162
JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:9725914 RGD:9685132 NCBI chrNW_004624828:2,727,136...2,805,248
Ensembl chrNW_004624828:2,727,112...2,807,319
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chrNW_004624819:732,118...735,391
Ensembl chrNW_004624819:732,268...735,313
JBrowse link
G Egfr epidermal growth factor receptor is_active_in ISO (PMID:11331309) ARUK-UCL PMID:11331309 NCBI chrNW_004624740:584,133...713,205
Ensembl chrNW_004624740:589,606...713,271
JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 located_in ISO (PMID:18794329) MGI PMID:18794329 NCBI chrNW_004624732:24,908,711...25,088,246
Ensembl chrNW_004624732:24,908,723...25,088,244
JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:22,250,988...22,424,957
Ensembl chrNW_004624752:22,295,413...22,426,717
JBrowse link
G Eps8l1 EPS8 signaling adaptor L1 located_in ISO (PMID:14565974) UniProt PMID:14565974 NCBI chrNW_004624832:2,124,674...2,134,130
Ensembl chrNW_004624832:2,124,670...2,138,828
JBrowse link
G Eps8l2 EPS8 signaling adaptor L2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624766:21,775,467...21,790,496
Ensembl chrNW_004624766:21,775,326...21,787,553
JBrowse link
G Eps8l3 EPS8 signaling adaptor L3 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:5,502,020...5,515,704 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624795:3,373,313...3,391,509
Ensembl chrNW_004624795:3,373,000...3,391,602
JBrowse link
G Ezr ezrin located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624929:827,275...873,743
Ensembl chrNW_004624929:826,531...873,572
JBrowse link
G Fam107a family with sequence similarity 107 member A located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624822:5,577,686...5,593,608
Ensembl chrNW_004624822:5,579,690...5,582,321
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase located_in ISO (PMID:15561106) UniProt PMID:15561106 NCBI chrNW_004624764:11,482,719...11,513,215
Ensembl chrNW_004624764:11,489,685...11,513,270
JBrowse link
G Hip1r huntingtin interacting protein 1 related located_in ISO (PMID:14732715) ParkinsonsUK-UCL PMID:14732715 NCBI chrNW_004624747:22,876,183...22,897,557
Ensembl chrNW_004624747:22,876,276...22,896,584
JBrowse link
G Ifit5 interferon induced protein with tetratricopeptide repeats 5 located_in ISO (PMID:23317505) UniProt PMID:23317505 NCBI chrNW_004624737:297,012...303,449 JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J located_in ISO PMID:10593988 MGI PMID:10593988 RGD:633686 NCBI chrNW_004624747:7,591,718...7,602,153
Ensembl chrNW_004624747:7,592,429...7,601,883
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K located_in ISO (PMID:12556481) UniProt PMID:12556481 NCBI chrNW_004624786:4,213,430...4,236,930
Ensembl chrNW_004624786:4,214,916...4,236,563
JBrowse link
G Itga5 integrin subunit alpha 5 located_in ISO (PMID:14970227) BHF-UCL PMID:14970227 NCBI chrNW_004624904:2,418,140...2,439,945
Ensembl chrNW_004624904:2,417,269...2,440,087
JBrowse link
G Itgav integrin subunit alpha V located_in ISO (PMID:25063885) UniProt PMID:25063885 NCBI chrNW_004624899:3,235,434...3,292,584
Ensembl chrNW_004624899:3,239,112...3,291,586
JBrowse link
G Itgb1 integrin subunit beta 1 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149
JBrowse link
G Itgb3 integrin subunit beta 3 located_in ISO (PMID:25063885) UniProt PMID:25063885 NCBI chrNW_004624849:1,895,378...1,952,755
Ensembl chrNW_004624849:1,895,914...1,952,665
JBrowse link
G Jcad junctional cadherin 5 associated located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624805:2,819,299...2,901,394
Ensembl chrNW_004624805:2,819,751...2,902,430
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 located_in ISO (PMID:19559006) UniProt PMID:19559006 NCBI chrNW_004624736:5,260,761...5,444,234
Ensembl chrNW_004624736:5,379,728...5,444,234
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 located_in ISO (PMID:24591580) UniProt PMID:24591580 NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699
JBrowse link
G Macf1 microtubule actin crosslinking factor 1 located_in ISO (PMID:20937854) UniProt PMID:20937854 NCBI chrNW_004624764:21,663,516...22,015,866
Ensembl chrNW_004624764:21,782,162...22,014,676
JBrowse link
G Map2 microtubule associated protein 2 located_in ISO PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chrNW_004624765:6,476,544...6,758,959
Ensembl chrNW_004624765:6,476,346...6,546,116
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:12,868,006...12,887,616
Ensembl chrNW_004624746:12,867,679...12,887,578
JBrowse link
G Myo1c myosin IC ISO RGD PMID:22918957 RGD:11073622 NCBI chrNW_004624786:4,188,143...4,211,712
Ensembl chrNW_004624786:4,188,143...4,211,732
JBrowse link
G Myo6 myosin VI located_in ISO
IEA
RGD
UniProt
PMID:9852149 GO_REF:0000044 RGD:2314969 NCBI chrNW_004624819:2,835,783...2,999,819
Ensembl chrNW_004624819:2,896,374...2,999,819
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 located_in ISO (PMID:20404169) UniProt PMID:20404169 NCBI chrNW_004624754:22,723,479...22,762,262
Ensembl chrNW_004624754:22,723,317...22,734,344
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624752:5,927,096...6,041,458
Ensembl chrNW_004624752:5,950,890...6,041,466
JBrowse link
G Pdpn podoplanin located_in ISO (PMID:17046996) UniProt PMID:17046996 NCBI chrNW_004624764:163,370...192,770 JBrowse link
G Pdxp pyridoxal phosphatase located_in ISO (PMID:15580268) UniProt PMID:15580268 NCBI chrNW_004624752:10,244,424...10,251,072
Ensembl chrNW_004624752:10,243,135...10,251,082
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase type 1 alpha located_in ISO (PMID:20660631)
(PMID:15870270)
UniProt
MGI
PMID:15870270 PMID:20660631 NCBI chrNW_004624772:18,616,095...18,658,016
Ensembl chrNW_004624772:18,616,121...18,658,286
JBrowse link
G Pla2g4f phospholipase A2 group IVF located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624804:9,271,237...9,286,101
Ensembl chrNW_004624804:9,271,674...9,279,991
JBrowse link
G Plcg1 phospholipase C gamma 1 is_active_in
located_in
ISO
IEA
(PMID:11331309) ARUK-UCL
TreeGrafter
PMID:11331309 GO_REF:0000118 NCBI chrNW_004624919:1,766,533...1,800,130
Ensembl chrNW_004624919:1,766,149...1,803,097
JBrowse link
G Plcg2 phospholipase C gamma 2 is_active_in
located_in
ISO
IEA
(PMID:11331309) ARUK-UCL
TreeGrafter
PMID:11331309 GO_REF:0000118 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Plek pleckstrin located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:4,939,683...4,967,327
Ensembl chrNW_004624762:4,939,599...4,967,371
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:24,299,199...24,365,459 JBrowse link
G Plekho1 pleckstrin homology domain containing O1 located_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:17,889,528...17,898,739
Ensembl chrNW_004624772:17,889,560...17,901,213
JBrowse link
G Ppp1r9b protein phosphatase 1 regulatory subunit 9B located_in ISO (PMID:19151759) UniProt PMID:19151759 NCBI chrNW_004624795:6,124,273...6,137,776
Ensembl chrNW_004624795:6,124,159...6,137,955
JBrowse link
G Psd pleckstrin and Sec7 domain containing located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624831:1,810,372...1,823,708
Ensembl chrNW_004624831:1,809,518...1,823,318
JBrowse link
G Psd2 pleckstrin and Sec7 domain containing 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624743:32,572,976...32,616,922
Ensembl chrNW_004624743:32,573,044...32,616,864
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 located_in IEA UniProt
TreeGrafter
GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624758:14,474,626...14,965,281
Ensembl chrNW_004624758:14,483,447...14,793,268
JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 located_in IEA UniProt
TreeGrafter
GO_REF:0000044 GO_REF:0000118 NCBI chrNW_004624749:13,250,146...13,288,672
Ensembl chrNW_004624749:13,250,095...13,310,750
JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J located_in ISO (PMID:19268662) UniProt PMID:19268662 NCBI chrNW_004624767:942,786...1,051,112
Ensembl chrNW_004624767:945,553...1,051,138
JBrowse link
G Ptprz1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:11381105 RGD:9589125 NCBI chrNW_004624783:13,911,525...14,105,403
Ensembl chrNW_004624783:13,912,332...14,105,292
JBrowse link
G Rab34 RAB34, member RAS oncogene family NOT|located_in ISO (PMID:17881736) UniProt PMID:17881736 NCBI chrNW_004624786:1,286,886...1,291,582
Ensembl chrNW_004624786:1,286,887...1,291,419
JBrowse link
G Rac1 Rac family small GTPase 1 located_in ISO (PMID:20875796)
(PMID:10934045)
UniProt PMID:10934045 PMID:20875796 NCBI chrNW_004624740:30,912,841...30,933,882
Ensembl chrNW_004624740:30,911,598...30,934,025
JBrowse link
G Rhoa ras homolog family member A located_in ISO (PMID:9214622) MGI PMID:9214622 NCBI chrNW_004624730:3,316,122...3,361,820 JBrowse link
G Rigi RNA sensor RIG-I located_in ISO (PMID:19122199) UniProt PMID:19122199 NCBI chrNW_004624736:37,134,718...37,204,543
Ensembl chrNW_004624736:37,133,059...37,197,218
JBrowse link
G Rps3 ribosomal protein S3 located_in ISO (PMID:16814409) UniProt PMID:16814409 NCBI chrNW_004624817:1,710,768...1,715,923
Ensembl chrNW_004624817:1,710,768...1,716,224
JBrowse link
G Sh3bgrl3 SH3 domain binding glutamate rich protein like 3 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624764:10,317,026...10,318,562
Ensembl chrNW_004624764:10,317,031...10,318,635
JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624846:1,707,606...1,735,959
Ensembl chrNW_004624846:1,706,966...1,735,475
JBrowse link
G Sntg1 syntrophin gamma 1 located_in ISO (PMID:15485858) UniProt PMID:15485858 NCBI chrNW_004624735:4,757,825...5,647,328
Ensembl chrNW_004624735:4,758,511...5,063,007
JBrowse link
G Spata13 spermatogenesis associated 13 located_in ISO (PMID:19151759) UniProt PMID:19151759 NCBI chrNW_004624776:13,703,451...13,852,924 JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624751:20,091,612...20,096,581
Ensembl chrNW_004624751:20,091,609...20,096,563
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase located_in ISO (PMID:17623777) MGI PMID:17623777 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132
JBrowse link
G Synj2 synaptojanin 2 ISO when coexpressed with constitutively GTP-bound Rac1 RGD PMID:11498538 RGD:628465 NCBI chrNW_004624785:157,455...265,926
Ensembl chrNW_004624785:145,228...266,022
JBrowse link
G Tesc tescalcin located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624747:16,189,032...16,228,211
Ensembl chrNW_004624747:16,188,949...16,228,211
JBrowse link
G Them4 thioesterase superfamily member 4 located_in IEA UniProt GO_REF:0000044 NCBI chrNW_004624772:19,673,079...19,704,635
Ensembl chrNW_004624772:19,673,066...19,698,710
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO RGD PMID:12446731 RGD:629540 NCBI chrNW_004624745:19,563,166...19,941,511
Ensembl chrNW_004624745:19,561,195...19,760,095
JBrowse link
G Tirap TIR domain containing adaptor protein located_in ISO (PMID:16751103) BHF-UCL PMID:16751103 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Tpm1 tropomyosin 1 located_in ISO (PMID:12686598) BHF-UCL PMID:12686598 NCBI chrNW_004624781:9,414,500...9,442,357
Ensembl chrNW_004624781:9,414,500...9,442,544
JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chrNW_004624747:10,675,625...10,685,351 JBrowse link
G Twf1 twinfilin actin binding protein 1 located_in ISO (PMID:12807912) BHF-UCL PMID:12807912 NCBI chrNW_004624816:8,765,937...8,780,301
Ensembl chrNW_004624816:8,765,922...8,778,396
JBrowse link
G Wwc1 WW and C2 domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:21,541,654...21,712,604
Ensembl chrNW_004624733:21,542,389...21,712,457
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15721
    cellular anatomical structure 15626
      leading edge membrane 166
        ruffle membrane 85
Path 2
Term Annotations click to browse term
  cellular_component 15721
    cellular anatomical structure 15626
      membrane 7605
        plasma membrane 4721
          plasma membrane region 1344
            cell projection membrane 332
              ruffle membrane 85
paths to the root