Sh3yl1 (SH3 and SYLF domain containing 1) - Rat Genome Database

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Gene: Sh3yl1 (SH3 and SYLF domain containing 1) Heterocephalus glaber
Analyze
Symbol: Sh3yl1
Name: SH3 and SYLF domain containing 1
RGD ID: 18927795
Description: ENCODES a protein that exhibits phosphatase binding (ortholog); INVOLVED IN phosphatidylinositol biosynthetic process (ortholog); regulation of ruffle assembly (ortholog); FOUND IN ruffle membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SH3 domain containing, Ysc84-like 1; SH3 domain-containing YSC84-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248461,706,966 - 1,735,475 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248461,707,606 - 1,735,959 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sh3yl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248461,706,966 - 1,735,475 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248461,707,606 - 1,735,959 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SH3YL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,136 - 264,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2217,730 - 266,398 (-)EnsemblGRCh38hg38GRCh38
GRCh372218,136 - 264,824 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362208,155 - 254,158 (-)NCBINCBI36Build 36hg18NCBI36
Build 342208,154 - 246,341NCBI
Celera2281,261 - 326,708 (-)NCBICelera
Cytogenetic Map2p25.3NCBI
HuRef2215,050 - 260,628 (-)NCBIHuRef
CHM1_12218,094 - 264,005 (-)NCBICHM1_1
T2T-CHM13v2.02218,391 - 265,079 (-)NCBIT2T-CHM13v2.0
Sh3yl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391230,961,622 - 31,010,159 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1230,961,667 - 31,010,161 (+)EnsemblGRCm39 Ensembl
GRCm381230,911,669 - 30,960,160 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1230,911,668 - 30,960,162 (+)EnsemblGRCm38mm10GRCm38
MGSCv371231,596,534 - 31,645,014 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361231,498,273 - 31,546,203 (+)NCBIMGSCv36mm8
Celera1232,364,576 - 32,412,974 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.01NCBI
Sh3yl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8653,250,036 - 53,293,406 (+)NCBIGRCr8
mRatBN7.2647,522,098 - 47,565,858 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl647,522,091 - 47,565,858 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx647,828,368 - 47,871,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0648,143,278 - 48,186,579 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0647,588,332 - 47,631,563 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0649,851,778 - 49,895,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl649,852,130 - 49,895,510 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0658,531,131 - 58,574,825 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4648,799,328 - 48,842,807 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1648,809,941 - 48,845,933 (+)NCBI
Celera646,727,614 - 46,770,741 (+)NCBICelera
Cytogenetic Map6q16NCBI
Sh3yl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955487257,869 - 289,832 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955487258,116 - 290,377 (-)NCBIChiLan1.0ChiLan1.0
SH3YL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212126,283,158 - 126,329,060 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A126,287,134 - 126,333,036 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A211,952 - 257,266 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A208,156 - 253,574 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A208,156 - 252,938 (-)Ensemblpanpan1.1panPan2
SH3YL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.117202,166 - 239,508 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl17201,452 - 238,481 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha17192,799 - 229,883 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.017260,747 - 297,833 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl17260,734 - 298,095 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.117187,780 - 224,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.017205,742 - 242,829 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.017210,633 - 247,722 (-)NCBIUU_Cfam_GSD_1.0
Sh3yl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629245,346,525 - 45,365,296 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653299,215 - 127,493 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936532101,571 - 127,331 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3YL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3132,684,960 - 132,730,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13132,684,836 - 132,731,003 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SH3YL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114107,465,977 - 107,515,448 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14107,467,666 - 107,516,219 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660454,428,543 - 4,476,592 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000001491   ⟹   ENSHGLP00000001447
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248461,706,966 - 1,735,475 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000001492   ⟹   ENSHGLP00000001448
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248461,707,779 - 1,735,286 (-)Ensembl
RefSeq Acc Id: XM_004868300   ⟹   XP_004868357
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,726,401 (-)NCBI
RefSeq Acc Id: XM_004868301   ⟹   XP_004868358
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,726,408 (-)NCBI
RefSeq Acc Id: XM_004868302   ⟹   XP_004868359
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,735,587 (-)NCBI
RefSeq Acc Id: XM_021247263   ⟹   XP_021102922
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,726,405 (-)NCBI
RefSeq Acc Id: XM_021247264   ⟹   XP_021102923
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,735,587 (-)NCBI
RefSeq Acc Id: XM_021247265   ⟹   XP_021102924
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,726,398 (-)NCBI
RefSeq Acc Id: XM_021247266   ⟹   XP_021102925
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248461,707,606 - 1,735,959 (-)NCBI
RefSeq Acc Id: XP_021102925   ⟸   XM_021247266
- Peptide Label: isoform X5
RefSeq Acc Id: XP_004868359   ⟸   XM_004868302
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JUK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102923   ⟸   XM_021247264
- Peptide Label: isoform X5
RefSeq Acc Id: XP_004868358   ⟸   XM_004868301
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021102922   ⟸   XM_021247263
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004868357   ⟸   XM_004868300
- Peptide Label: isoform X1
- UniProtKB: G5C0X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102924   ⟸   XM_021247265
- Peptide Label: isoform X5
Ensembl Acc Id: ENSHGLP00000001448   ⟸   ENSHGLT00000001492
Ensembl Acc Id: ENSHGLP00000001447   ⟸   ENSHGLT00000001491


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001117 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100008481 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001491 ENTREZGENE
  ENSHGLT00000001492 UniProtKB/TrEMBL
  ENSHGLT00100011552 UniProtKB/TrEMBL
  ENSHGLT00100011553 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
InterPro SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SH3_domain_YSC84-like UniProtKB/TrEMBL
  SH3YL1_SH3 UniProtKB/TrEMBL
  SYLF_SH3YL1-like UniProtKB/TrEMBL
  Ysc84_actin-binding UniProtKB/TrEMBL
KEGG Report hgl:101703830 UniProtKB/TrEMBL
NCBI Gene Sh3yl1 ENTREZGENE
PANTHER SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1 UniProtKB/TrEMBL
  SH3YL1 PROTEIN UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  Ysc84 UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
UniProt A0A0P6JUK0 ENTREZGENE, UniProtKB/TrEMBL
  G5C0X6 ENTREZGENE, UniProtKB/TrEMBL