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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translational initiation by eIF2 alpha phosphorylation
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Accession:GO:0010998 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
Comment:Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'.
Synonyms:exact_synonym: eIF2 alpha phosphorylation in response to stress;   regulation of translational initiation by eIF2 alpha phosphorylation in response to stress


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negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS		 (PMID:22064321)
GO_REF:0000024
(MGI:5617428|PMID:25329545)		 RGD
UniProt		 PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
UniProtKB:O55033 (MGI:5613478|PMID:14676213)
GO_REF:0000033		 RGD
GO_Central		 PMID:14676213 GO_REF:0000033 MGI:5613478 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (MGI:5613478|PMID:14676213)
GO_REF:0000033		 RGD
GO_Central		 PMID:14676213 GO_REF:0000033 MGI:5613478 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4456438 (PMID:28797121)		 Ensembl
RGD		 PMID:28797121 GO_REF:0000107 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:12882984)
GO_REF:0000024		 RGD
UniProt		 PMID:12882984 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1353448|MGI:95513 (PMID:15931390)		 Ensembl
RGD		 PMID:15931390 GO_REF:0000107 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:1858114|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hbb hemoglobin subunit beta acts_upstream_of_or_within ISO MGI:1857179 (PMID:15931390) RGD PMID:15931390 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749)		 UniProt
RGD		 PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      macromolecule metabolic process 9387
        protein metabolic process 4605
          protein modification process 2016
            protein phosphorylation 795
              regulation of translational initiation by eIF2 alpha phosphorylation 10
                eiF2alpha phosphorylation in response to endoplasmic reticulum stress + 6
                regulation of eIF2 alpha phosphorylation by dsRNA 1
                regulation of eIF2 alpha phosphorylation by heme 3
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological process 12902
        regulation of metabolic process 6482
          regulation of biosynthetic process 5325
            regulation of cellular biosynthetic process 5234
              regulation of macromolecule biosynthetic process 5135
                regulation of gene expression 5020
                  post-transcriptional regulation of gene expression 769
                    regulation of translation 485
                      regulation of translational initiation 70
                        regulation of translational initiation in response to stress 14
                          regulation of translational initiation by eIF2 alpha phosphorylation 10
                            eiF2alpha phosphorylation in response to endoplasmic reticulum stress + 6
                            regulation of eIF2 alpha phosphorylation by dsRNA 1
                            regulation of eIF2 alpha phosphorylation by heme 3
paths to the root