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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of low-density lipoprotein particle clearance
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Accession:GO:0010989 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


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negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 involved_in ISO RGD
MGI		 PMID:23828271 GO_REF:0000096 MGI:4417868 RGD:12792253 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934 		JBrowse link
G Csk c-src tyrosine kinase involved_in ISO RGD
MGI		 PMID:10884975 GO_REF:0000096 MGI:4417868 RGD:5134370 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914 		JBrowse link
G Il19 interleukin 19 involved_in IMP (MGI:6102526|PMID:28257760) BHF-UCL PMID:28257760 MGI:6102526 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:57,328,049...57,338,507
Ensembl chr17:57,328,051...57,338,522 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Mir133a-1 microRNA 133a-1 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chr18:10,782,909...10,782,976
Ensembl chr18:10,782,909...10,782,976 		JBrowse link
G Mir133a-2 microRNA 133a-2 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chr 2:180,040,172...180,040,275
Ensembl chr 2:180,040,172...180,040,275 		JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) BHF-UCL PMID:26437365 NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) ARUK-UCL PMID:23285084 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in		 ISO (PMID:24296663)
(PMID:26523989)		 BHF-UCL PMID:24296663 PMID:26523989 NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329 		JBrowse link
G Mir199a-1 microRNA 199a-1 involved_in ISO (PMID:26163491) BHF-UCL PMID:26163491 NCBI chr 9:21,407,791...21,407,860
Ensembl chr 9:21,407,791...21,407,860 		JBrowse link
G Mir199a-2 microRNA 199a-2 involved_in ISO (PMID:26163491) BHF-UCL PMID:26163491 NCBI chr 1:162,045,383...162,045,492
Ensembl chr 1:162,045,383...162,045,492 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) BHF-UCL PMID:26318398 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) BHF-UCL PMID:26520906 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in IDA (MGI:3849777|PMID:19520913) BHF-UCL PMID:19520913 MGI:3849777 NCBI chr13:45,543,197...45,565,498
Ensembl chr13:45,543,218...45,565,498 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    multicellular organismal process 8916
      plasma lipoprotein particle clearance 50
        low-density lipoprotein particle clearance 33
          negative regulation of low-density lipoprotein particle clearance 17
Path 2
Term Annotations click to browse term
  biological_process 28576
    biological regulation 13125
      regulation of biological process 12730
        regulation of plasma lipoprotein particle levels 83
          plasma lipoprotein particle clearance 50
            low-density lipoprotein particle clearance 33
              regulation of low-density lipoprotein particle clearance 24
                negative regulation of low-density lipoprotein particle clearance 17
paths to the root