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ONTOLOGY REPORT - ANNOTATIONS


Term:low-density lipoprotein particle clearance
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Accession:GO:0034383 term browser browse the term
Definition:The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: LDL clearance


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low-density lipoprotein particle clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07059308.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:14,071,507...14,113,255 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO
ISS
(PMID:11222466)
GO_REF:0000024
RGD
UniProt
PMID:11222466 GO_REF:0000024 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Apob apolipoprotein B ISO (PMID:15797858), (PMID:2563166) RGD PMID:2563166 PMID:15797858 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Cd36 CD36 molecule ISO
IBA
(PMID:10772654)
PMID:21873635
(MGI:3836139|PMID:10772654)
RGD PMID:10772654, PMID:21873635 MGI:3836139, RGD:13792537 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Commd1 copper metabolism domain containing 1 ISO MGI:2176228|MGI:5315712 (MGI:5806548|PMID:26965651) RGD PMID:26965651 MGI:5806548 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Ehd1 EH-domain containing 1 ISO (MGI:3711403|PMID:17451652) RGD PMID:17451652 MGI:3711403 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Ldlr low density lipoprotein receptor IEA
ISO
GO_REF:0000107
(MGI:3784112|PMID:18175806), (MGI:5806548|PMID:26965651)
(PMID:17142622), (PMID:6299582)
Ensembl
RGD
PMID:6299582 PMID:17142622 PMID:18175806 PMID:26965651 GO_REF:0000107 MGI:3784112 MGI:5806548 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:8071607 RGD:2308769 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G LOC103690020 platelet glycoprotein 4-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:14,205,811...14,241,272
Ensembl chr 4:14,212,925...14,241,272
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Washc1 WASH complex subunit 1 IEA
ISO
GO_REF:0000107
(MGI:5806548|PMID:26965651)
Ensembl
RGD
PMID:26965651 GO_REF:0000107 MGI:5806548 NCBI chr 9:113,918,914...113,936,861
Ensembl chr 9:113,918,858...113,936,860
JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Apoc3 apolipoprotein C3 ISO
IBA
(PMID:15778093)
PMID:21873635
RGD PMID:15778093, PMID:21873635 RGD:13792537 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Il19 interleukin 19 ISO (MGI:6102526|PMID:28257760) RGD PMID:28257760 MGI:6102526 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Khsrp KH-type splicing regulatory protein ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Mylip myosin regulatory light chain interacting protein ISO (MGI:3849777|PMID:19520913) RGD PMID:19520913 MGI:3849777 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:17328821), (PMID:22848640) RGD PMID:17328821 PMID:22848640 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
positive regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:28257760) RGD PMID:28257760 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnpy2 canopy FGF signaling regulator 2 ISO (MGI:5427047|PMID:22378787) RGD PMID:22378787 MGI:5427047 NCBI chr 7:2,737,674...2,744,321
Ensembl chr 7:2,737,765...2,742,369
JBrowse link
G Crp C-reactive protein IDA RGD PMID:8305421 RGD:9586002 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO
IEA
(PMID:20371611)
GO_REF:0000107
RGD
Ensembl
PMID:20371611 GO_REF:0000107 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEA
ISO
GO_REF:0000107
(PMID:12660231)
Ensembl
RGD
PMID:12660231 GO_REF:0000107 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    multicellular organismal process 9040
      plasma lipoprotein particle clearance 39
        low-density lipoprotein particle clearance 25
          negative regulation of low-density lipoprotein particle clearance 7
          positive regulation of low-density lipoprotein particle clearance 2
          regulation of low-density lipoprotein particle clearance + 13
Path 2
Term Annotations click to browse term
  biological_process 20044
    biological regulation 13855
      regulation of biological process 13106
        regulation of plasma lipoprotein particle levels 69
          plasma lipoprotein particle clearance 39
            low-density lipoprotein particle clearance 25
              negative regulation of low-density lipoprotein particle clearance 7
              positive regulation of low-density lipoprotein particle clearance 2
              regulation of low-density lipoprotein particle clearance + 13
paths to the root