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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma lipoprotein particle clearance
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Accession:GO:0034381 term browser browse the term
Definition:The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: lipoprotein particle clearance



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plasma lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO (MGI:2447499|PMID:12376530) RGD PMID:12376530 MGI:2447499 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (MGI:5902678|PMID:22383525) RGD PMID:22383525 MGI:5902678 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Msr1 macrophage scavenger receptor 1 involved_in IBA
ISO
PMID:21873635
(MGI:2447499|PMID:12376530)
RGD PMID:12376530 PMID:21873635 MGI:2447499, RGD:13792537 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:4020294) RGD PMID:4020294 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in IBA
ISO
PMID:21873635
(PMID:4020294)
RGD PMID:4020294 PMID:21873635 RGD:13792537 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:4020294)
GO_REF:0000107
RGD
Ensembl
PMID:4020294 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:1911868), (PMID:7175379)
Ensembl
UniProt
RGD
PMID:1911868 PMID:7175379 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:8192680 RGD:2308768 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (MGI:55554|PMID:6857276) RGD PMID:6857276 MGI:55554 NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
JBrowse link
high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:10764676) RGD PMID:10764676 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoc2 apolipoprotein C2 involved_in IBA
ISO
PMID:21873635
(PMID:15778093)
RGD PMID:15778093 PMID:21873635 RGD:13792537 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:210175)
GO_REF:0000107
RGD
Ensembl
PMID:210175 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M involved_in IBA
ISO
PMID:21873635
(MGI:3575626|PMID:15793583)
RGD PMID:15793583 PMID:21873635 MGI:3575626, RGD:13792537 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO
GO_REF:0000107
RNAcentral:URS0000070CD2_10090 (MGI:5896906|PMID:25524771)
Ensembl
RGD
PMID:25524771 GO_REF:0000107 MGI:5896906 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO
ISS
(PMID:9211901)
GO_REF:0000024
RGD
BHF-UCL
PMID:9211901 GO_REF:0000024 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
intermediate-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA
ISS
(PMID:1917954)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:1917954 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07059308.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:11222466)
GO_REF:0000024
RGD
UniProt
PMID:11222466 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Apob apolipoprotein B involved_in ISO (PMID:15797858), (PMID:2563166) RGD PMID:2563166 PMID:15797858 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Cd36 CD36 molecule involved_in IBA
ISO
PMID:21873635
(MGI:3836139|PMID:10772654)
(PMID:10772654)
RGD PMID:10772654 PMID:21873635 MGI:3836139, RGD:13792537 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Commd1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO MGI:2176228|MGI:5315712 (MGI:5806548|PMID:26965651) RGD PMID:26965651 MGI:5806548 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Ehd1 EH-domain containing 1 involved_in ISO (MGI:3711403|PMID:17451652) RGD PMID:17451652 MGI:3711403 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5806548|PMID:26965651)
(MGI:3784112|PMID:18175806)
(PMID:17142622), (PMID:6299582)
Ensembl
RGD
PMID:6299582 PMID:17142622 PMID:18175806 PMID:26965651 GO_REF:0000107 MGI:3784112 MGI:5806548 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:8071607 RGD:2308769 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G RGD1565355 similar to fatty acid translocase/CD36 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISO (MGI:3784112|PMID:18175806) RGD PMID:18175806 MGI:3784112 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Washc1 WASH complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5806548|PMID:26965651)
Ensembl
RGD
PMID:26965651 GO_REF:0000107 MGI:5806548 NCBI chr 9:105,722,779...105,830,836
Ensembl chr 9:105,722,899...105,733,009
JBrowse link
negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:15778093)
Ensembl
RGD
PMID:15778093 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Apoc3 apolipoprotein C3 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:15778093)
Ensembl
RGD
PMID:15778093 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Il19 interleukin 19 involved_in ISO (MGI:6102526|PMID:28257760) RGD PMID:28257760 MGI:6102526 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (MGI:3849777|PMID:19520913) RGD PMID:19520913 MGI:3849777 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640) RGD PMID:17328821 PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in IBA
ISO
PMID:21873635
(PMID:1917954)
RGD PMID:1917954 PMID:21873635 RGD:13792537 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO
IBA
(PMID:1917954)
PMID:21873635
RGD PMID:1917954 PMID:21873635 RGD:13792537 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:1917954)
Ensembl
RGD
PMID:1917954 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G LOC100910181 apolipoprotein C-I-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Lrpap1 LDL receptor related protein associated protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:8083232)
RGD PMID:8083232 PMID:21873635 RGD:13792537 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
oxidised low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO (PMID:27607416) RGD PMID:27607416 NCBI chr 4:17,317,343...17,410,084 JBrowse link
positive regulation of chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in ISO (MGI:3770110|PMID:17403372) RGD PMID:17403372 MGI:3770110 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
JBrowse link
positive regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3617276|PMID:16219662)
UniProt
RGD
PMID:16219662 GO_REF:0000024 MGI:3617276 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) RGD PMID:19136670 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6342648|PMID:31257031) RGD PMID:31257031 MGI:6342648 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
positive regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6342648|PMID:31257031) RGD PMID:31257031 MGI:6342648 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnpy2 canopy FGF signaling regulator 2 acts_upstream_of ISO (MGI:5427047|PMID:22378787) RGD PMID:22378787 MGI:5427047 NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
JBrowse link
G Crp C-reactive protein IDA RGD PMID:8305421 RGD:9586002 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of
involved_in
ISO
IEA
(PMID:20371611)
GO_REF:0000107
RGD
Ensembl
PMID:20371611 GO_REF:0000107 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA
(PMID:12660231)
GO_REF:0000107
RGD
Ensembl
PMID:12660231 GO_REF:0000107 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
triglyceride-rich lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISS
ISO
GO_REF:0000024
(MGI:5514108|PMID:23676495)
(PMID:23676495)
UniProt
RGD
PMID:23676495 GO_REF:0000024 MGI:5514108 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in IBA
ISO
PMID:21873635
(PMID:15576844)
RGD PMID:15576844 PMID:21873635 RGD:13792537 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:1917954), (PMID:2762297), (PMID:9649566)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:1917954 PMID:2762297 PMID:9649566 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G LOC100910181 apolipoprotein C-I-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Vldlr very low density lipoprotein receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:8083232)
Ensembl
BHF-UCL
RGD
PMID:8083232 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    multicellular organismal process 8821
      plasma lipoprotein particle clearance 39
        high-density lipoprotein particle clearance + 10
        low-density lipoprotein particle clearance + 26
        negative regulation of lipoprotein particle clearance + 11
        oxidised low-density lipoprotein particle clearance 1
        positive regulation of lipoprotein particle clearance + 6
        regulation of lipoprotein particle clearance + 21
        triglyceride-rich lipoprotein particle clearance + 7
        very-low-density lipoprotein particle clearance + 7
Path 2
Term Annotations click to browse term
  biological_process 19390
    biological regulation 13476
      regulation of biological process 12735
        regulation of plasma lipoprotein particle levels 69
          plasma lipoprotein particle clearance 39
            high-density lipoprotein particle clearance + 10
            low-density lipoprotein particle clearance + 26
            negative regulation of lipoprotein particle clearance + 11
            oxidised low-density lipoprotein particle clearance 1
            positive regulation of lipoprotein particle clearance + 6
            regulation of lipoprotein particle clearance + 21
            triglyceride-rich lipoprotein particle clearance + 7
            very-low-density lipoprotein particle clearance + 7
paths to the root