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ONTOLOGY REPORT - ANNOTATIONS

Term:plasma lipoprotein particle clearance
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Accession:GO:0034381 term browser browse the term
Definition:The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms:exact_synonym: lipoprotein particle clearance


show annotations for term's descendants           Sort by:
plasma lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO (PMID:12376530) RGD PMID:12376530 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:22383525) RGD PMID:22383525 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Msr1 macrophage scavenger receptor 1 involved_in IBA
ISO		 GO_REF:0000033
(PMID:12376530)		 GO_Central
RGD		 PMID:12376530 GO_REF:0000033 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:4020294) RGD PMID:4020294 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO
IBA		 (PMID:4020294)
GO_REF:0000033		 RGD
GO_Central		 PMID:4020294 GO_REF:0000033 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:4020294) RGD PMID:4020294 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:1911868), (PMID:7175379), (PMID:7683668)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:1911868 PMID:7175379 PMID:7683668 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:8192680 RGD:2308768 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO MGI:1856820 (PMID:6857276) RGD PMID:6857276 NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119 		JBrowse link
high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:10764676) RGD PMID:10764676 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO
IBA		 (PMID:15778093)
GO_REF:0000033		 RGD
GO_Central		 PMID:15778093 GO_REF:0000033 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA		 (PMID:210175)
GO_REF:0000107		 RGD
Ensembl		 PMID:210175 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apom apolipoprotein M involved_in IBA
ISO		 GO_REF:0000033
(PMID:15793583)		 GO_Central
RGD		 PMID:15793583 GO_REF:0000033 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO		 GO_REF:0000107
RNAcentral:URS0000070CD2_10090 (PMID:25524771)		 Ensembl
RGD		 PMID:25524771 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23459944), (PMID:9211901)		 BHF-UCL
Ensembl
RGD		 PMID:9211901 PMID:23459944 GO_REF:0000024 GO_REF:0000107 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
intermediate-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA
ISS		 (PMID:1917954)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:1917954 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS		 (PMID:11222466)
GO_REF:0000024		 RGD
UniProt		 PMID:11222466 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Apob apolipoprotein B involved_in ISO
IEA		 (PMID:15797858), (PMID:2563166)
GO_REF:0000107		 RGD
Ensembl		 PMID:2563166 PMID:15797858 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Cd36 CD36 molecule involved_in ISO
IBA
IEA		 (PMID:10772654)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10772654 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Commd1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO MGI:2176228|MGI:5315712 (PMID:26965651) RGD PMID:26965651 NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18175806)		 Ensembl
RGD		 PMID:18175806 GO_REF:0000107 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Ehd1 EH-domain containing 1 involved_in ISO (PMID:17451652) RGD PMID:17451652 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:17142622), (PMID:6299582)
(PMID:18175806)
(PMID:26965651)
GO_REF:0000107		 RGD
Ensembl		 PMID:6299582 PMID:17142622 PMID:18175806 PMID:26965651 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO
IEA		 (PMID:12417523), (PMID:12464675), (PMID:15166224)
GO_REF:0000107		 RGD
Ensembl		 PMID:12417523 PMID:12464675 PMID:15166224 GO_REF:0000107 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Lipc lipase C, hepatic type IDA RGD PMID:8071607 RGD:2308769 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18175806)		 Ensembl
RGD		 PMID:18175806 GO_REF:0000107 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Washc1 WASH complex subunit 1 acts_upstream_of_or_within ISO (PMID:26965651) RGD PMID:26965651 NCBI chr 9:105,722,779...105,830,836
Ensembl chr 9:105,722,899...105,733,009 		JBrowse link
negative regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO
IBA		 (PMID:15778093)
GO_REF:0000033		 RGD
GO_Central		 PMID:15778093 GO_REF:0000033 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir223 microRNA 223 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:23459944) RGD PMID:23459944 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
negative regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:23828271 RGD:12792253 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IBA		 (PMID:15778093)
GO_REF:0000033		 RGD
GO_Central		 PMID:15778093 GO_REF:0000033 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Il19 interleukin 19 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO RNAcentral:URS00004176D4_9606 (PMID:26523989) RGD PMID:26523989 NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO
IEA		 (PMID:17452316)
GO_REF:0000107		 RGD
Ensembl		 PMID:17452316 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir148a microRNA 148a involved_in ISO (PMID:26437365) RGD PMID:26437365 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:23285084) RGD PMID:23285084 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of
involved_in		 ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:24296663)
(PMID:26523989)		 RGD PMID:24296663 PMID:26523989 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:26163491) RGD PMID:26163491 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:26318398) RGD PMID:26318398 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:26520906) RGD PMID:26520906 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Mylip myosin regulatory light chain interacting protein involved_in ISO (PMID:19520913) RGD PMID:19520913 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:17328821), (PMID:22848640) RGD PMID:17328821 PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
negative regulation of very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO
IBA		 (PMID:1917954)
GO_REF:0000033		 RGD
GO_Central		 PMID:1917954 GO_REF:0000033 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) RGD PMID:1917954 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IBA		 (PMID:1917954)
GO_REF:0000033		 RGD
GO_Central		 PMID:1917954 GO_REF:0000033 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO
IBA		 (PMID:8083232)
GO_REF:0000033		 RGD
GO_Central		 PMID:8083232 GO_REF:0000033 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414 		JBrowse link
oxidised low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO
IEA		 (PMID:27607416)
GO_REF:0000107		 RGD
Ensembl		 PMID:27607416 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
positive regulation of chylomicron remnant clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in ISO (PMID:17403372) RGD PMID:17403372 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702 		JBrowse link
positive regulation of high-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16219662)		 UniProt
RGD		 PMID:16219662 GO_REF:0000024 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Lipg lipase G, endothelial type involved_in ISO (PMID:19136670) RGD PMID:19136670 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31257031) RGD PMID:31257031 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO
IEA		 (PMID:22848640)
GO_REF:0000107		 RGD
Ensembl		 PMID:22848640 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO
IEA		 (PMID:28257760)
GO_REF:0000107		 RGD
Ensembl		 PMID:28257760 GO_REF:0000107 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31257031) RGD PMID:31257031 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnpy2 canopy FGF signaling regulator 2 acts_upstream_of ISO (PMID:22378787) RGD PMID:22378787 NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519 		JBrowse link
G Crp C-reactive protein IDA RGD PMID:8305421 RGD:9586002 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of
involved_in		 ISO
IEA		 (PMID:20371611)
GO_REF:0000107		 RGD
Ensembl		 PMID:20371611 GO_REF:0000107 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G LOC100359916 heterogeneous nuclear ribonucleoprotein K-like involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:58,668,326...58,670,222
Ensembl chr 5:58,668,327...58,670,220 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (PMID:12660231)
GO_REF:0000107		 RGD
Ensembl		 PMID:12660231 GO_REF:0000107 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
triglyceride-rich lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISS
ISO		 GO_REF:0000024
(PMID:23676495)		 UniProt
RGD		 PMID:23676495 GO_REF:0000024 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:6364606 (PMID:33357458)		 Ensembl
RGD		 PMID:33357458 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
very-low-density lipoprotein particle clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO
IBA		 (PMID:15576844)
GO_REF:0000033		 RGD
GO_Central		 PMID:15576844 GO_REF:0000033 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:1917954), (PMID:2762297), (PMID:7683668), (PMID:9649566)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:1917954 PMID:2762297 PMID:7683668 PMID:9649566 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:8083232)		 Ensembl
BHF-UCL
RGD		 PMID:8083232 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      plasma lipoprotein particle clearance 48
        high-density lipoprotein particle clearance + 13
        low-density lipoprotein particle clearance + 33
        negative regulation of lipoprotein particle clearance + 21
        oxidised low-density lipoprotein particle clearance 1
        positive regulation of lipoprotein particle clearance + 6
        regulation of lipoprotein particle clearance + 32
        triglyceride-rich lipoprotein particle clearance + 8
        very-low-density lipoprotein particle clearance + 6
Path 2
Term Annotations click to browse term
  biological_process 20076
    biological regulation 13559
      regulation of biological process 13136
        regulation of plasma lipoprotein particle levels 80
          plasma lipoprotein particle clearance 48
            high-density lipoprotein particle clearance + 13
            low-density lipoprotein particle clearance + 33
            negative regulation of lipoprotein particle clearance + 21
            oxidised low-density lipoprotein particle clearance 1
            positive regulation of lipoprotein particle clearance + 6
            regulation of lipoprotein particle clearance + 32
            triglyceride-rich lipoprotein particle clearance + 8
            very-low-density lipoprotein particle clearance + 6
paths to the root