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ONTOLOGY REPORT - ANNOTATIONS

Term:production of molecular mediator involved in inflammatory response
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Accession:GO:0002532 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:broad_synonym: production of molecular mediator involved in acute inflammatory response
 related_synonym: production of cellular mediator of acute inflammation

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production of molecular mediator involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (MGI:5619466|PMID:20610799) CACAO PMID:20610799 MGI:5619466 NCBI chr14:98,092,093...98,157,657
Ensembl chr14:98,092,044...98,157,217 		JBrowse link
G IL4R interleukin 4 receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:25,019,638...25,069,732
Ensembl chr 5:25,046,701...25,070,015 		JBrowse link
G LOC103228738 group 10 secretory phospholipase A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,135,279...14,160,346
Ensembl chr 5:14,135,338...14,159,885 		JBrowse link
G PBXIP1 PBX homeobox interacting protein 1 acts_upstream_of_or_within ISO (PMID:30659184) MGI PMID:30659184 NCBI chr20:8,872,492...8,884,029
Ensembl chr20:8,872,409...8,884,450 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28947740) Ensembl
MGI		 PMID:28947740 GO_REF:0000107 NCBI chr19:14,025,373...14,033,214
Ensembl chr19:14,025,742...14,030,643 		JBrowse link
arachidonic acid metabolite production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADS2 fatty acid desaturase 2 ISO RGD PMID:24284026 RGD:401901245 NCBI chr 1:11,934,352...11,978,355
Ensembl chr 1:11,934,270...11,974,030 		JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO RGD PMID:12220673 RGD:1600535 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G LOC103224223 adenosine receptor A3 acts_upstream_of_or_within ISO (PMID:12817016) MGI PMID:12817016 NCBI chr20:22,043,367...22,127,103
Ensembl chr20:22,106,190...22,123,629 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G RAB44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:32238914) MGI PMID:32238914 NCBI chr17:35,399,866...35,435,599 JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:110,039,783...110,078,822
Ensembl chr 9:110,040,391...110,076,647 		JBrowse link
G SNAP23 synaptosome associated protein 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:40,443,478...40,485,211
Ensembl chr26:40,442,615...40,482,346 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO RGD PMID:12499633 RGD:1625716 NCBI chr 8:95,786,197...95,821,270
Ensembl chr 8:95,788,305...95,819,197 		JBrowse link
histamine secretion mediated by IgE immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB44 RAB44, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:32238914) MGI PMID:32238914 NCBI chr17:35,399,866...35,435,599 JBrowse link
leukotriene production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9091580) Ensembl
MGI		 PMID:9091580 GO_REF:0000107 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10779800), (PMID:9091580) Ensembl
MGI		 PMID:9091580 PMID:10779800 GO_REF:0000107 NCBI chr 3:9,618,030...9,642,990
Ensembl chr 3:9,617,949...9,643,184 		JBrowse link
negative regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 involved_in ISO (MGI:3836690|PMID:18723473) UniProt PMID:18723473 MGI:3836690 NCBI chr  X:128,152,697...128,171,007 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in ISO (MGI:3836690|PMID:18723473) UniProt PMID:18723473 MGI:3836690 NCBI chr11:35,818,451...35,884,696 JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr11:35,866,928...35,884,503 JBrowse link
G ADCY7 adenylate cyclase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,086,680...36,122,021
Ensembl chr 5:36,065,319...36,113,921 		JBrowse link
G APOD apolipoprotein D involved_in ISO (PMID:18842892) UniProt PMID:18842892 NCBI chr15:89,612,210...89,624,038
Ensembl chr15:89,612,040...89,624,012 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:100,400,093...100,469,234
Ensembl chr11:100,400,084...100,462,507 		JBrowse link
G CHID1 chitinase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:675,978...716,068
Ensembl chr 1:676,074...716,006 		JBrowse link
G CUEDC2 CUE domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24882011) MGI
Ensembl		 PMID:24882011 GO_REF:0000107 NCBI chr 9:95,454,936...95,463,491
Ensembl chr 9:95,451,470...95,463,454 		JBrowse link
G EPHB2 EPH receptor B2 ISO RGD PMID:33722292 RGD:127285641 NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777 		JBrowse link
G EXTL3 exostosin like glycosyltransferase 3 involved_in ISO (PMID:28811323) UniProt PMID:28811323 NCBI chr 8:26,729,772...26,861,953
Ensembl chr 8:26,821,141...26,864,926 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:27690696 RGD:126781724 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 NCBI chr14:5,672,434...5,708,270
Ensembl chr14:5,673,163...5,708,372 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) ARUK-UCL PMID:19380766 NCBI chr 6:47,299,764...47,333,711 JBrowse link
G LOC103223491 peroxisome proliferator-activated receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763 		JBrowse link
G LOC103228738 group 10 secretory phospholipase A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,135,279...14,160,346
Ensembl chr 5:14,135,338...14,159,885 		JBrowse link
G LOC103236354 prothrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511 		JBrowse link
G MACIR macrophage immunometabolism regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:26316022) MGI
TreeGrafter		 PMID:26316022 GO_REF:0000118 NCBI chr23:6,695,131...6,714,925
Ensembl chr23:6,712,171...6,712,791 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in ISO (PMID:26347139) UniProt PMID:26347139 NCBI chr 5:2,971,323...2,991,501 JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:2,971,419...2,981,911 JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chr 5:3,241,552...3,262,763
Ensembl chr 5:3,242,242...3,262,261 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,534,730...47,560,380
Ensembl chr 6:47,539,594...47,552,265 		JBrowse link
G PDCD4 programmed cell death 4 involved_in ISO (MGI:3707264|PMID:17114484), (MGI:4438829|PMID:19946272) BHF-UCL PMID:17114484 PMID:19946272 MGI:3707264 MGI:4438829 NCBI chr 9:103,809,005...103,836,402
Ensembl chr 9:103,813,211...103,836,002 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452
G PYCARD PYD and CARD domain containing involved_in ISO (PMID:24531343) UniProt PMID:24531343 NCBI chr 5:27,892,332...27,894,386
Ensembl chr 5:27,889,230...27,893,697 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in ISO (MGI:6189251|PMID:23562609)
(MGI:3760575|PMID:17954568)		 ARUK-UCL PMID:17954568 PMID:23562609 MGI:3760575 MGI:6189251 NCBI chr 2:54,590,151...54,636,381 JBrowse link
G SPINK7 serine peptidase inhibitor Kazal type 7 acts_upstream_of_or_within ISO (PMID:33722746) MGI PMID:33722746 NCBI chr23:50,957,730...50,961,702
Ensembl chr23:50,958,270...50,961,467 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6391726|PMID:29887864) ARUK-UCL PMID:29887864 MGI:6391726 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960 		JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO (PMID:19696743) MGI PMID:19696743 NCBI chr25:7,790,969...7,833,485
Ensembl chr25:7,792,913...7,834,346 		JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:62,037,344...62,045,765
Ensembl chr16:62,036,412...62,045,614 		JBrowse link
G INS insulin involved_in ISO (PMID:11443198) BHF-UCL PMID:11443198 NCBI chr 1:1,965,128...1,969,090 JBrowse link
G LOC103223747 SLAM family member 8 acts_upstream_of_or_within ISO (PMID:25799045) MGI PMID:25799045 NCBI chr20:4,114,403...4,127,122
Ensembl chr20:4,116,630...4,124,988 		JBrowse link
G RPS19 ribosomal protein S19 involved_in ISO (PMID:15750715) UniProt PMID:15750715 NCBI chr 6:36,067,959...36,085,581 JBrowse link
nitric oxide production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A2 solute carrier family 7 member 2 acts_upstream_of_or_within ISO (PMID:11278602), (PMID:17003120) MGI PMID:11278602 PMID:17003120 NCBI chr 8:15,591,795...15,665,837
Ensembl chr 8:15,638,113...15,660,487 		JBrowse link
G TLR4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:10623794) MGI PMID:10623794 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
positive regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD42 ankyrin repeat domain 42 acts_upstream_of_or_within ISO (PMID:20547855) MGI PMID:20547855 NCBI chr 1:74,388,272...74,569,529 JBrowse link
G ANKRD42 ankyrin repeat domain 42 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 1:74,389,237...74,444,831 JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:5698780|PMID:25328665) UniProt PMID:25328665 MGI:5698780 NCBI chr22:18,546,694...18,591,239
Ensembl chr22:18,546,751...18,589,552 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in ISO (MGI:5618187|PMID:25267792) UniProt PMID:25267792 MGI:5618187 NCBI chr12:1,829,913...1,841,489
Ensembl chr12:1,832,989...1,837,914 		JBrowse link
G CD6 CD6 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:12,827,238...12,878,304
Ensembl chr 1:12,828,285...12,877,704 		JBrowse link
G CD74 CD74 molecule involved_in ISO (PMID:23736979) AgBase PMID:23736979 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:9,989,520...10,007,442
Ensembl chr11:9,995,203...10,006,746 		JBrowse link
G GPSM3 G protein signaling modulator 3 acts_upstream_of_or_within ISO (PMID:23280397) MGI PMID:23280397 NCBI chr17:39,839,010...39,841,213 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G IL17A interleukin 17A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:29734196)
(PMID:16785495)
(PMID:17982105)		 ARUK-UCL
MGI
Ensembl		 PMID:16785495 PMID:17982105 PMID:29734196 GO_REF:0000107 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785 		JBrowse link
G IL17B interleukin 17B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17982105) Ensembl
MGI		 PMID:17982105 GO_REF:0000107 NCBI chr23:51,992,877...52,001,280
Ensembl chr23:51,993,258...51,998,043 		JBrowse link
G IL17C interleukin 17C acts_upstream_of_or_within ISO (PMID:17982105) MGI PMID:17982105 NCBI chr 5:74,019,253...74,021,530
Ensembl chr 5:74,019,253...74,020,344 		JBrowse link
G IL17D interleukin 17D involved_in ISO (PMID:12097364) UniProt PMID:12097364 NCBI chr 3:401,525...421,725 JBrowse link
G IL17D interleukin 17D involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 3:402,634...421,090 JBrowse link
G IL17F interleukin 17F acts_upstream_of_or_within ISO (PMID:16785495), (PMID:17982105) MGI PMID:16785495 PMID:17982105 NCBI chr17:20,263,252...20,272,234
Ensembl chr17:20,264,481...20,271,982 		JBrowse link
G IL17RC interleukin 17 receptor C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16785495) Ensembl
MGI		 PMID:16785495 GO_REF:0000107 NCBI chr22:45,944,385...45,960,188
Ensembl chr22:45,944,669...45,960,164 		JBrowse link
G IL6 interleukin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G KPNA6 karyopherin subunit alpha 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28189564) Ensembl
MGI		 PMID:28189564 GO_REF:0000107 NCBI chr20:100,699,653...100,769,787
Ensembl chr20:100,701,947...100,769,766 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in ISO (PMID:8654373)
(PMID:27830702)		 UniProt PMID:8654373 PMID:27830702 NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:24671169) CACAO PMID:24671169 NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28947740) Ensembl
MGI		 PMID:28947740 GO_REF:0000107 NCBI chr19:14,025,373...14,033,214
Ensembl chr19:14,025,742...14,030,643 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) UniProt PMID:26311901 MGI:5908526 NCBI chr 6:46,749,522...46,755,192
Ensembl chr 6:46,749,580...46,754,799 		JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr27:11,439,288...11,461,580
Ensembl chr27:11,459,181...11,461,571 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:31824476)
(PMID:23608026)		 ARUK-UCL PMID:23608026 PMID:31824476
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr20:119,942,412...119,946,211
Ensembl chr20:119,944,532...119,945,917 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,025,373...14,033,214
Ensembl chr19:14,025,742...14,030,643 		JBrowse link
G SNX4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr22:55,311,896...55,389,174
Ensembl chr22:55,311,933...55,389,349 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:129,937,026...129,984,071
Ensembl chr  X:129,937,046...129,984,119 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr14:21,575,057...21,580,054
Ensembl chr14:21,575,161...21,579,820 		JBrowse link
positive regulation of leukotriene production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE1 serpin family E member 1 involved_in ISO (PMID:19916862) BHF-UCL PMID:19916862 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202 		JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LBP lipopolysaccharide binding protein involved_in ISO (MGI:1097829|PMID:9338787) BHF-UCL PMID:9338787 MGI:1097829 NCBI chr 2:25,375,364...25,407,181
Ensembl chr 2:25,374,755...25,406,839 		JBrowse link
G RPS19 ribosomal protein S19 involved_in ISO (PMID:15750715) UniProt PMID:15750715 NCBI chr 6:36,067,959...36,085,581 JBrowse link
prostaglandin production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:16962614 RGD:5688387 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G BAP1 BRCA1 associated protein 1 acts_upstream_of_or_within ISO (PMID:26119930) MGI PMID:26119930 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740 		JBrowse link
G LEP leptin involved_in ISO (PMID:19688109) UniProt PMID:19688109 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in ISO (PMID:19688109) UniProt PMID:19688109 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
G PER1 period circadian regulator 1 involved_in ISO PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr16:7,520,122...7,536,176
Ensembl chr16:7,520,006...7,531,940 		JBrowse link
G PLD3 phospholipase D family member 3 involved_in ISO (MGI:5308480|PMID:22102906) UniProt PMID:22102906 MGI:5308480 NCBI chr 6:34,804,574...34,833,975
Ensembl chr 6:34,804,500...34,836,333 		JBrowse link
G PLD4 phospholipase D family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:82,848,775...82,857,359
Ensembl chr24:82,851,238...82,857,579 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695683|PMID:29663649) ARUK-UCL PMID:29663649 MGI:6695683 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNX6 sorting nexin 6 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr24:11,389,436...11,433,126
Ensembl chr24:11,388,329...11,433,545 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr16:7,539,098...7,542,466 JBrowse link
G VAMP3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr20:123,973,672...123,984,230
Ensembl chr20:123,971,992...123,984,187 		JBrowse link
regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NCF1 neutrophil cytosolic factor 1 ISO RGD PMID:21275845 RGD:41404729 NCBI chr28:8,334,172...8,349,828
Ensembl chr28:8,332,772...8,349,804 		JBrowse link
respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33357458)
(PMID:25807535)		 Ensembl
MGI		 PMID:25807535 PMID:33357458 GO_REF:0000107 NCBI chr 9:82,639,220...82,677,479
Ensembl chr 9:82,638,621...82,677,488 		JBrowse link
G PRDX2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:17325201) MGI PMID:17325201 NCBI chr 6:11,484,452...11,489,067
Ensembl chr 6:11,481,784...11,489,051 		JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103243088 CMRF35-like molecule 8 acts_upstream_of_or_within ISO (PMID:12874256) MGI PMID:12874256 NCBI chr16:47,153,766...47,173,780
Ensembl chr16:47,154,437...47,170,038 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:110,039,783...110,078,822
Ensembl chr 9:110,040,391...110,076,647 		JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc fragment of IgE receptor Ig involved_in ISO (MGI:87668|PMID:9171347) UniProt PMID:9171347 MGI:87668 NCBI chr20:2,763,412...2,767,774
Ensembl chr20:2,763,417...2,767,248 		JBrowse link
G P2RX1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (PMID:12913094) MGI PMID:12913094 NCBI chr16:3,377,526...3,399,374
Ensembl chr16:3,377,483...3,398,360 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16523
    multicellular organismal process 7191
      production of molecular mediator involved in inflammatory response 101
        arachidonic acid metabolite production involved in inflammatory response + 5
        cytokine production involved in inflammatory response + 66
        histamine production involved in inflammatory response + 15
        lysosomal enzyme production involved in inflammatory response + 0
        nitric oxide production involved in inflammatory response 2
        platelet activating factor production involved in inflammatory response 0
        respiratory burst involved in inflammatory response + 9
        serotonin production involved in inflammatory response + 5
Path 2
Term Annotations click to browse term
  biological_process 16523
    response to stimulus 8465
      response to stress 3896
        defense response 1641
          inflammatory response 770
            production of molecular mediator involved in inflammatory response 101
              arachidonic acid metabolite production involved in inflammatory response + 5
              cytokine production involved in inflammatory response + 66
              histamine production involved in inflammatory response + 15
              lysosomal enzyme production involved in inflammatory response + 0
              nitric oxide production involved in inflammatory response 2
              platelet activating factor production involved in inflammatory response 0
              respiratory burst involved in inflammatory response + 9
              serotonin production involved in inflammatory response + 5
paths to the root