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ONTOLOGY REPORT - ANNOTATIONS


Term:cytokine production involved in inflammatory response
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Accession:GO:0002534 term browser browse the term
Definition:The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
Synonyms:broad_synonym: cytokine production involved in acute inflammatory response


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negative regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISS
ISO
GO_REF:0000024
(MGI:3836690|PMID:18723473)
UniProt
RGD
PMID:18723473 GO_REF:0000024 MGI:3836690 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 ISS
ISO
GO_REF:0000024
(MGI:3836690|PMID:18723473)
UniProt
RGD
PMID:18723473 GO_REF:0000024 MGI:3836690 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Adcy7 adenylate cyclase 7 ISO (MGI:4459338|PMID:20505140) RGD PMID:20505140 MGI:4459338 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Apod apolipoprotein D ISO
ISS
(PMID:18842892)
GO_REF:0000024
RGD
UniProt
PMID:18842892 GO_REF:0000024 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (MGI:5698780|PMID:25328665) RGD PMID:25328665 MGI:5698780 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Chid1 chitinase domain containing 1 ISO (PMID:20724479) RGD PMID:20724479 NCBI chr 1:214,476,418...214,511,569
Ensembl chr 1:214,476,387...214,511,529
JBrowse link
G Cuedc2 CUE domain containing 2 ISO (PMID:24882011)
MGI:5635142 (MGI:5576401|PMID:24882011)
RGD PMID:24882011 MGI:5576401 NCBI chr 1:266,078,107...266,087,057
Ensembl chr 1:266,078,108...266,086,299
JBrowse link
G F2 coagulation factor II IEA
ISO
GO_REF:0000107
(PMID:20421939)
Ensembl
RGD
PMID:20421939 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Il1r2 interleukin 1 receptor type 2 IEA
ISO
GO_REF:0000107
(MGI:5468848|PMID:23395675)
Ensembl
RGD
PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G Macir macrophage immunometabolism regulator ISO
IBA
(MGI:5698579|PMID:26316022)
PMID:21873635
RGD PMID:26316022, PMID:21873635 MGI:5698579, RGD:13792537 NCBI chr 9:111,327,333...111,347,428
Ensembl chr 9:111,327,402...111,347,430
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO
ISS
(PMID:26347139)
GO_REF:0000024
RGD
UniProt
PMID:26347139 GO_REF:0000024 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Pdcd4 programmed cell death 4 ISO (MGI:3707264|PMID:17114484), (MGI:4438829|PMID:19946272) RGD PMID:17114484 PMID:19946272 MGI:3707264 MGI:4438829 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pla2g10 phospholipase A2, group X IEA
ISO
GO_REF:0000107
MGI:4412409 (MGI:5779244|PMID:26828067)
Ensembl
RGD
PMID:26828067 GO_REF:0000107 MGI:5779244 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO
IEA
(PMID:31574452)
GO_REF:0000107
RGD
Ensembl
PMID:31574452 GO_REF:0000107 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pycard PYD and CARD domain containing ISO (PMID:24531343) RGD PMID:24531343 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Sirpa signal-regulatory protein alpha IEA
ISO
GO_REF:0000107
RNAcentral:URS00002075FA_10090 (MGI:3760575|PMID:17954568), (MGI:6189251|PMID:23562609)
Ensembl
RGD
PMID:17954568 PMID:23562609 GO_REF:0000107 MGI:3760575 MGI:6189251 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISS
ISO
GO_REF:0000024
(MGI:5142149|PMID:21616078)
UniProt
RGD
PMID:21616078 GO_REF:0000024 MGI:5142149 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
positive regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd42 ankyrin repeat domain 42 ISO (MGI:4458950|PMID:20547855) RGD PMID:20547855 MGI:4458950 NCBI chr 1:157,419,117...157,461,588
Ensembl chr 1:157,419,123...157,461,588
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (MGI:5698780|PMID:25328665) RGD PMID:25328665 MGI:5698780 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Cd6 Cd6 molecule ISO (PMID:17601777) RGD PMID:17601777 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Cd74 CD74 molecule ISO (PMID:23736979) RGD PMID:23736979 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Clec7a C-type lectin domain containing 7A ISO
IBA
(PMID:22267217)
PMID:21873635
RGD PMID:22267217, PMID:21873635 RGD:13792537 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Gbp5 guanylate binding protein 5 ISO (MGI:5319585|PMID:22461501) RGD PMID:22461501 MGI:5319585 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Gpsm3 G-protein signaling modulator 3 ISO MGI:4075252 (MGI:5468060|PMID:23280397) RGD PMID:23280397 MGI:5468060 NCBI chr20:4,355,246...4,357,107
Ensembl chr20:4,355,175...4,357,107
JBrowse link
G Il17a interleukin 17A IEA
ISO
GO_REF:0000107
MGI:107399|MGI:2159336 (MGI:3785663|PMID:16785495), (MGI:4366407|PMID:17982105)
(PMID:29734196)
Ensembl
RGD
PMID:16785495 PMID:17982105 PMID:29734196 GO_REF:0000107 MGI:3785663 MGI:4366407 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17b interleukin 17B ISO (MGI:4366407|PMID:17982105) RGD PMID:17982105 MGI:4366407 NCBI chr18:57,011,575...57,016,009
Ensembl chr18:57,011,575...57,016,009
JBrowse link
G Il17c interleukin 17C ISO (MGI:4366407|PMID:17982105) RGD PMID:17982105 MGI:4366407 NCBI chr19:55,246,926...55,248,688
Ensembl chr19:55,246,926...55,248,205
JBrowse link
G Il17d interleukin 17D ISO (PMID:12097364) RGD PMID:12097364 NCBI chr15:37,790,211...37,807,653
Ensembl chr15:37,790,141...37,807,660
JBrowse link
G Il17f interleukin 17F IEA
ISO
GO_REF:0000107
MGI:107399 (MGI:3785663|PMID:16785495), (MGI:4366407|PMID:17982105)
Ensembl
RGD
PMID:16785495 PMID:17982105 GO_REF:0000107 MGI:3785663 MGI:4366407 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219
JBrowse link
G Il17ra interleukin 17 receptor A ISO MGI:107364|MGI:2676631 (MGI:3785663|PMID:16785495) RGD PMID:16785495 MGI:3785663 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il17rc interleukin 17 receptor C ISO MGI:107364 (MGI:3785663|PMID:16785495) RGD PMID:16785495 MGI:3785663 NCBI chr 4:145,426,647...145,439,845
Ensembl chr 4:145,427,367...145,439,843
JBrowse link
G Il6 interleukin 6 ISO RNAcentral:URS00004E0808_9606 (PMID:31886314) RGD PMID:31886314 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kpna6 karyopherin subunit alpha 6 ISO MGI:3856636 (MGI:5898166|PMID:28189564) RGD PMID:28189564 MGI:5898166 NCBI chr 5:147,852,738...147,867,600
Ensembl chr 5:147,850,275...147,886,615
JBrowse link
G Mir324 microRNA 324 ISO (MGI:5576401|PMID:24882011) RGD PMID:24882011 MGI:5576401 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO (PMID:20219467)
(MGI:4438693|PMID:20037584)
RGD PMID:20037584 PMID:20219467 MGI:4438693 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (PMID:24671169) RGD PMID:24671169 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Pla2g3 phospholipase A2, group III ISO MGI:4461174 (MGI:6108995|PMID:28947740) RGD PMID:28947740 MGI:6108995 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314) RGD PMID:31886314 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 ISO (MGI:5908526|PMID:26311901) RGD PMID:26311901 MGI:5908526 NCBI chr 1:64,241,742...64,256,646
Ensembl chr 1:64,241,865...64,254,564
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 ISO (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr 9:10,780,185...10,790,280 JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
UniProtKB:Q9Y2C9 (MGI:4438693|PMID:20037584)
(PMID:30321456)
Ensembl
RGD
PMID:20037584 PMID:30321456 GO_REF:0000107 MGI:4438693 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr6 toll-like receptor 6 ISO UniProtKB:O00206 (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
G Tnf tumor necrosis factor ISO RNAcentral:URS00004DA9DB_9606 (PMID:23608026), (PMID:31824476) RGD PMID:23608026 PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
regulation of cytokine production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISS
ISO
IEA
GO_REF:0000024
(MGI:6392964|PMID:28965882)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28965882 GO_REF:0000024 GO_REF:0000107 MGI:6392964 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Bap1 Brca1 associated protein 1 IEA
ISO
GO_REF:0000107
MGI:5439653 (MGI:5789498|PMID:26119930)
Ensembl
RGD
PMID:26119930 GO_REF:0000107 MGI:5789498 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Lep leptin ISO
ISS
(PMID:19688109)
GO_REF:0000024
RGD
UniProt
PMID:19688109 GO_REF:0000024 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO
IEA
(PMID:15251176)
GO_REF:0000107
RGD
Ensembl
PMID:15251176 GO_REF:0000107 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:31490757 RGD:26884457 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Nos2 nitric oxide synthase 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19688109)
Ensembl
UniProt
RGD
PMID:19688109 GO_REF:0000024 GO_REF:0000107 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Per1 period circadian regulator 1 IMP PMID:24447840 UniProt PMID:24447840 RGD:8655527 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pld3 phospholipase D family, member 3 ISS
ISO
GO_REF:0000024
(MGI:5308480|PMID:22102906)
UniProt
RGD
PMID:22102906 GO_REF:0000024 MGI:5308480 NCBI chr 1:84,339,269...84,361,686
Ensembl chr 1:84,339,261...84,353,725
JBrowse link
G Pld4 phospholipase D family, member 4 ISO (MGI:5308480|PMID:22102906) RGD PMID:22102906 MGI:5308480 NCBI chr 6:137,323,713...137,331,231
Ensembl chr 6:137,323,713...137,331,231
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    multicellular organismal process 9040
      cytokine production 740
        cytokine production involved in inflammatory response 54
          negative regulation of cytokine production involved in inflammatory response 19
          positive regulation of cytokine production involved in inflammatory response 26
          regulation of cytokine production involved in inflammatory response + 54
Path 2
Term Annotations click to browse term
  biological_process 20044
    response to stimulus 10558
      response to stress 4042
        defense response 1664
          inflammatory response 722
            production of molecular mediator involved in inflammatory response 85
              cytokine production involved in inflammatory response 54
                negative regulation of cytokine production involved in inflammatory response 19
                positive regulation of cytokine production involved in inflammatory response 26
                regulation of cytokine production involved in inflammatory response + 54
paths to the root