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ONTOLOGY REPORT - ANNOTATIONS

Term:luteolysis
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Accession:GO:0001554 term browser browse the term
Definition:The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
Synonyms:xref: Wikipedia:Luteolysis


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luteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP12 caspase 12 (gene/pseudogene) ISO RGD PMID:25332219 RGD:13782179 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP2 caspase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16940287 GO_REF:0000107 RGD:4107077 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696 		JBrowse link
G CASP3 caspase 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25332219 GO_REF:0000107 RGD:13782179 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO RGD PMID:25332219 RGD:13782179 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 ISO RGD PMID:21209419 RGD:155663486 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:25332219 RGD:13782179 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:8835383 RGD:7207087 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP13 matrix metallopeptidase 13 ISO RGD PMID:10537164 RGD:7207086 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP19 matrix metallopeptidase 19 ISO RGD PMID:15286033 RGD:1642024 NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966 		JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21209419 GO_REF:0000107 RGD:155663486 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH4 notch receptor 4 ISO RGD PMID:21209419 RGD:155663486 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:11444430 RGD:1642472 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
apoptotic process involved in luteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ROBO2 roundabout guidance receptor 2 involved_in IEP (PMID:18566128) UniProt PMID:18566128 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEP (PMID:18566128) UniProt PMID:18566128 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561 		JBrowse link
G SLIT3 slit guidance ligand 3 involved_in IEP (PMID:18566128) UniProt PMID:18566128 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,740...169,301,139 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    reproductive process 2036
      ovulation cycle process 88
        luteolysis 15
          apoptotic process involved in luteolysis 3
          negative regulation of progesterone biosynthesis involved in luteolysis 0
Path 2
Term Annotations click to browse term
  biological_process 19613
    developmental process 7604
      anatomical structure development 7016
        multicellular organism development 5629
          system development 4907
            reproductive system development 480
              reproductive structure development 475
                gonad development 381
                  female gonad development 166
                    luteolysis 15
                      apoptotic process involved in luteolysis 3
                      negative regulation of progesterone biosynthesis involved in luteolysis 0
paths to the root