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Gene: PLA2G4A (phospholipase A2 group IVA) Homo sapiens
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Symbol: PLA2G4A
Name: phospholipase A2 group IVA
RGD ID: 735872
Description: Exhibits several functions, including calcium ion binding activity; phospholipase activity; and phospholipid binding activity. Involved in glycerolipid metabolic process; icosanoid metabolic process; and positive regulation of platelet activation. Localizes to several cellular components, including Golgi membrane; lipid droplet; and nuclear envelope.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium-dependent phospholipid-binding protein; cPLA2; cPLA2-alpha; cytosolic phospholipase A2; GURDP; lysophospholipase; MGC126350; phosphatidylcholine 2-acylhydrolase; phospholipase A2, group IVA (cytosolic, calcium-dependent); PLA2G4
Orthologs:
Mus musculus (house mouse) : Pla2g4a (phospholipase A2, group IVA (cytosolic, calcium-dependent))  MGI  Alliance
Rattus norvegicus (Norway rat) : Pla2g4a (phospholipase A2 group IVA)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g4a (phospholipase A2 group IVA)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G4A (phospholipase A2 group IVA)
Canis lupus familiaris (dog) : PLA2G4A (phospholipase A2 group IVA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g4a (phospholipase A2 group IVA)
Sus scrofa (pig) : PLA2G4A (phospholipase A2 group IVA)
Chlorocebus sabaeus (African green monkey) : PLA2G4A (phospholipase A2 group IVA)
Heterocephalus glaber (naked mole-rat) : Pla2g4a (phospholipase A2 group IVA)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1186,828,949 - 186,988,981 (+)EnsemblGRCh38hg38GRCh38
GRCh381186,828,949 - 186,988,981 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371186,798,032 - 186,958,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,064,655 - 185,224,736 (+)NCBINCBI36hg18NCBI36
Build 341183,529,761 - 183,689,770NCBI
Celera1159,908,366 - 160,068,522 (+)NCBI
Cytogenetic Map1q31.1NCBI
HuRef1158,032,476 - 158,192,352 (+)NCBIHuRef
CHM1_11188,219,298 - 188,379,410 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
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References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLA2G4A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735872
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.