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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Anorexia
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Accession:DOID:9001109 term browser browse the term
Definition:The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
Synonyms:exact_synonym: Anorexias
 primary_id: MESH:D000855


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Anorexia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:6534893 RGD:10047083 NCBI chr 3:33,913,068...33,960,804
Ensembl chr 3:33,908,970...34,015,474 		JBrowse link
G CCK cholecystokinin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22903826 PMID:24385417 NCBI chr13:25,940,674...25,945,879
Ensembl chr13:25,937,645...25,945,793 		JBrowse link
G CRH corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12429558 PMID:16420149 RGD:704394 NCBI chr 4:68,481,696...68,486,122
Ensembl chr 4:68,484,053...68,486,121 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16420149 NCBI chr12:17,251,361...17,306,308
Ensembl chr12:17,252,020...17,306,285 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17050037 PMID:17627984 RGD:5131264 NCBI chr18:42,251,755...42,296,457
Ensembl chr18:42,251,749...42,295,467 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 susceptibility ISO DNA:SNP:promoter:g.-251A>T RGD PMID:24076593 RGD:150523788 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:20554938 RGD:5129235 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552 		JBrowse link
G GCG glucagon ISO CTD Direct Evidence: marker/mechanism CTD PMID:21824258 PMID:28633506 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GIP gastric inhibitory polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:28633506 PMID:28666375 PMID:29689362 NCBI chr12:25,160,783...25,167,952
Ensembl chr12:25,160,789...25,167,940 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO associated with Uremia RGD PMID:12005352 RGD:11352773 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ISO associated with Sarcoma;protein:increased expression:hypothalamus RGD PMID:15698923 RGD:1626473 NCBI chr 1:88,597,510...88,598,682
Ensembl chr 1:88,596,237...88,601,757 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15146954 NCBI chr 2:149,768,295...149,813,801
Ensembl chr 2:149,731,034...149,912,495 		JBrowse link
G IL1A interleukin 1 alpha ISO associated with Sarcoma, Experimental;protein:increased expression:cerebrospinal fluid RGD PMID:8748250 RGD:7794755 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic
associated with Adenocarcinoma;mRNA:increased expression:cerebral cortex, hypothalamus (rat)		 CTD
RGD		 PMID:9688694 PMID:25392278 RGD:8551744
G IL2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8635092 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19652058 NCBI chr14:7,344,788...7,371,086 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:hypothalamus		 CTD
RGD		 PMID:12077204 PMID:22902858 PMID:25392278 RGD:13825124
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:19821837 RGD:9835045 NCBI chr18:38,942,499...39,212,791
Ensembl chr18:38,942,487...39,085,754 		JBrowse link
G NPY neuropeptide Y ISO associated with Neoplasms
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16084549 PMID:16101753 PMID:17234300 PMID:25825358 RGD:10448965 NCBI chr18:47,985,796...47,993,726
Ensembl chr18:47,985,725...47,992,667 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO associated with Neoplasms;mRNA, protein:decreased expression:hypothalamus RGD PMID:17234300 RGD:10448965 NCBI chr 8:52,152,649...52,163,080
Ensembl chr 8:52,152,646...52,162,328 		JBrowse link
G OPRL1 opioid related nociceptin receptor 1 treatment ISO RGD PMID:11981590 RGD:9835031 NCBI chr17:62,905,700...62,913,018
Ensembl chr17:62,905,082...62,913,754 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment ISO RGD PMID:22902858 RGD:13825124 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PYY peptide YY ISO CTD Direct Evidence: marker/mechanism CTD PMID:22903826 PMID:29689362 NCBI chr12:19,190,703...19,208,373 JBrowse link
G TAC1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30336258 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25392278 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO CTD Direct Evidence: therapeutic CTD PMID:18801959 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,051...64,331,909 		JBrowse link
G UCN2 urocortin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17627984 NCBI chr13:31,261,196...31,261,824
Ensembl chr13:31,261,196...31,261,534 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15278
    Pathological Conditions, Signs and Symptoms 11851
      Signs and Symptoms 9805
        Digestive Signs and Symptoms 188
          Anorexia 27
            FACES Syndrome 0
paths to the root