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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:follicular thyroid carcinoma
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Accession:DOID:3962 term browser browse the term
Definition:A differentiated thyroid gland carcinoma that has_material_basis_in follicular cells. (DO)
Synonyms:exact_synonym: follicular adenocarcinoma;   follicular adenocarcinoma, well differentiated;   follicular adenocarcinomas;   follicular carcinoma;   follicular carcinoma of the thyroid gland;   follicular thyroid carcinomas;   thyroid adenocarcinoma;   thyroid gland follicular carcinoma
 narrow_synonym: poorly differentiated follicular thyroid carcinoma
 xref: EFO:0000501;   EFO:1002016;   ICD11:2D10.0;   ICDO:8330/3;   MESH:D018263;   MONDO:0005034;   NCI:C132275;   NCI:C8054
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
follicular thyroid carcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27440272 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISS OMIM:188470 MouseDO NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Pten phosphatase and tensin homolog ISS
ISO		 OMIM:188470
ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR		 MouseDO
ClinVar		 PMID:24033266 PMID:24055113 PMID:25741868 PMID:25980754 PMID:28492532 More... NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Srgap1 SLIT-ROBO Rho GTPase activating protein 1 ISO ClinVar Annotator: match by term: THYROID CARCINOMA, FOLLICULAR ClinVar PMID:23539728 NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196 		JBrowse link
G Thrb thyroid hormone receptor beta ISO
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:188470		 CTD
MouseDO		 PMID:27440272 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
oncocytic carcinoma of the thyroid term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbx7 chromobox 7 ISO protein:decreased expression:thyroid Human) RGD PMID:25759796 RGD:11352710 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 ISO ClinVar Annotator: match by term: Hurthle cell carcinoma of the thyroid
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:15841082 PMID:25741868 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
Ensembl chr 7:19,526,565...19,535,726 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 ISO RGD PMID:19924240 RGD:6483332 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19106
    disease of cellular proliferation 7915
      cancer 5769
        cell type cancer 3842
          carcinoma 3281
            adenocarcinoma 1714
              thyroid gland adenocarcinoma 74
                differentiated high-grade thyroid carcinoma 74
                  follicular thyroid carcinoma 12
                    oncocytic carcinoma of the thyroid 3
                    trabecular follicular adenocarcinoma 0
Path 2
Term Annotations click to browse term
  disease 19106
    disease of cellular proliferation 7915
      cancer 5769
        organ system cancer 5529
          endocrine gland cancer 2614
            thyroid cancer 102
              thyroid gland carcinoma 95
                thyroid gland adenocarcinoma 74
                  differentiated high-grade thyroid carcinoma 74
                    follicular thyroid carcinoma 12
                      oncocytic carcinoma of the thyroid 3
                      trabecular follicular adenocarcinoma 0
paths to the root