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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bongkrekic acid
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Accession:CHEBI:77742 term browser browse the term
Definition:A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group. It is produced by the bacterium Burkholderia gladioli and implicated in outbreaks of food-borne illness involving coconut and corn-based products in Indonesia and China.
Synonyms:exact_synonym: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid
 related_synonym: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-2,4,8,10,14,18,20-docosaheptaenedioic acid;   Formula=C28H38O7;   InChI=1S/C28H38O7/c1-21(15-18-24(19-26(29)30)20-27(31)32)13-11-9-7-5-6-8-10-12-14-25(35-4)22(2)16-17-23(3)28(33)34/h6,8-12,15-19,21,25H,5,7,13-14,20H2,1-4H3,(H,29,30)(H,31,32)(H,33,34)/b8-6+,11-9+,12-10-,18-15+,22-16-,23-17+,24-19+/t21-,25+/m0/s1;   InChIKey=SHCXABJSXUACKU-WUTQZGRKSA-N;   SMILES=CO[C@H](C\\C=C/C=C/CC\\C=C\\C[C@H](C)\\C=C\\C(\\CC(O)=O)=C/C(O)=O)C(\\C)=C/C=C(\\C)C(O)=O;   bongkrek acid
 xref: CAS:11076-19-0;   CBA:366918;   Chemspider:4938689
 xref_mesh: MESH:D001865
 xref: PDBeChem:BKC;   PMID:12034471;   PMID:15919152;   PMID:16430940;   PMID:17123460;   PMID:20237660;   PMID:2037079;   PMID:22050912;   PMID:22998163;   PMID:22999884;   PMID:23315986;   PMID:24522192;   PMID:25786526;   PMID:26032198;   PMID:26126659;   PMID:26548846;   PMID:27798877;   PMID:27823840;   PMID:28105575;   PMID:28769000;   PMID:29155976;   PMID:30611538;   PMID:31517068;   PMID:31518860;   PMID:31524538;   PMID:31642300;   PMID:33246684;   PMID:33459584;   PMID:34019862;   PMID:34079526;   PMID:7164105;   Patent:JP2005068064;   Reaxys:1717902;   Wikipedia:Bongkrek_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:178020



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bongkrekic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Bongkrekic Acid results in increased expression of ADIPOQ mRNA CTD PMID:25786526 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of DDIT3 protein] CTD PMID:29427785 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Bongkrekic Acid inhibits the reaction [N-caproylsphingosine results in increased expression of ICAM1 mRNA] CTD PMID:12952965 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il24 interleukin 24 decreases activity ISO Bongkrekic Acid results in decreased activity of IL24 protein CTD PMID:14678967 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G P2rx1 purinergic receptor P2X 1 increases activity ISO Bongkrekic Acid results in increased activity of P2RX1 protein CTD PMID:34019862 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G Padi4 peptidyl arginine deiminase 4 increases activity ISO Bongkrekic Acid results in increased activity of PADI4 protein CTD PMID:34019862 NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO Bongkrekic Acid analog results in increased activity of PPARG protein; Bongkrekic Acid results in increased activity of PPARG protein CTD PMID:25786526 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions EXP Bongkrekic Acid inhibits the reaction [oxophenylarsine binds to SLC25A4 protein] CTD PMID:18667415 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases activity ISO Bongkrekic Acid results in decreased activity of SLC25A5 protein CTD PMID:26746582 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link

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  CHEBI ontology 20089
    role 20042
      biological role 20011
        poison 18567
          toxin 15904
            bongkrekic acid 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        tricarboxylic acid 2460
                                          bongkrekic acid 10
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