Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bongkrekic acid
go back to main search page
Accession:CHEBI:77742 term browser browse the term
Definition:A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group.
Synonyms:exact_synonym: (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid
 related_synonym: Formula=C28H38O7;   InChI=1S/C28H38O7/c1-21(15-18-24(19-26(29)30)20-27(31)32)13-11-9-7-5-6-8-10-12-14-25(35-4)22(2)16-17-23(3)28(33)34/h6,8-12,15-19,21,25H,5,7,13-14,20H2,1-4H3,(H,29,30)(H,31,32)(H,33,34)/b8-6+,11-9+,12-10-,18-15+,22-16-,23-17+,24-19+/t21-,25+/m0/s1;   InChIKey=SHCXABJSXUACKU-WUTQZGRKSA-N;   SMILES=CO[C@H](C\\C=C/C=C/CC\\C=C\\C[C@H](C)\\C=C\\C(\\CC(O)=O)=C/C(O)=O)C(\\C)=C/C=C(\\C)C(O)=O
 xref: CAS:11076-19-0
 xref_mesh: MESH:D001865
 xref: PMID:12034471;   PMID:15919152;   PMID:17123460;   PMID:20237660;   PMID:2037079;   PMID:22050912;   PMID:22999884;   PMID:23315986;   PMID:24522192;   PMID:7164105;   Reaxys:1717902;   Wikipedia:Bongkrek_acid


show annotations for term's descendants           Sort by:
 
bongkrekic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Bongkrekic Acid results in increased expression of ADIPOQ mRNA CTD PMID:25786526 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein] CTD PMID:29427785 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Bongkrekic Acid inhibits the reaction [leflunomide results in increased expression of DDIT3 protein] CTD PMID:29427785 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Bongkrekic Acid inhibits the reaction [N-caproylsphingosine results in increased expression of ICAM1 mRNA] CTD PMID:12952965 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il24 interleukin 24 decreases activity ISO Bongkrekic Acid results in decreased activity of IL24 protein CTD PMID:14678967 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO Bongkrekic Acid analog results in increased activity of PPARG protein; Bongkrekic Acid results in increased activity of PPARG protein CTD PMID:25786526 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions EXP Bongkrekic Acid inhibits the reaction [oxophenylarsine binds to SLC25A4 protein] CTD PMID:18667415 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases activity ISO Bongkrekic Acid results in decreased activity of SLC25A5 protein CTD PMID:26746582 NCBI chr  X:123,404,570...123,407,637
Ensembl chr  X:123,404,518...123,407,645
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        poison 18080
          toxin 13949
            bongkrekic acid 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        tricarboxylic acid 2438
                                          bongkrekic acid 8
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.