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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621863
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atf4
Name: activating transcription factor 4
Acc ID: CHEBI:77742
Term: bongkrekic acid
Definition: A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group.
Chemical ID: MESH:D001865
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf4multiple interactionsISORGD:7337126480464CTDBongkrekic Acid inhibits the reaction [leflunomide results in increased expression of ATF4 protein]

PMID:29427785
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.