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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Ethyl pyruvate
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Accession:CHEBI:173421 term browser browse the term
Synonyms:exact_synonym: ethyl 2-oxopropanoate
 related_synonym: Formula=C5H8O3;   InChI=1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3;   InChIKey=XXRCUYVCPSWGCC-UHFFFAOYSA-N;   SMILES=O(CC)C(=O)C(=O)C
 xref: CAS:617-35-6;   Chemspider:11544;   DrugBank:DB05869;   HMDB:HMDB0031643
 xref_mesh: MESH:C046522
 xref: PDBeChem:9X7


show annotations for term's descendants           Sort by:
Ethyl pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of AGER protein] CTD PMID:30859215 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO ethyl pyruvate inhibits the reaction [Acetaminophen results in increased secretion of HMGB1 protein]; ethyl pyruvate inhibits the reaction [Dust affects the localization of HMGB1 protein] CTD PMID:21513726 PMID:30859215 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of and results in increased secretion of IL6 protein] CTD PMID:30859215 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO		 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK1 protein]
ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]		 CTD PMID:21316417 PMID:21818760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO		 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK3 protein]
ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]		 CTD PMID:21316417 PMID:21818760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK9 protein] CTD PMID:21818760 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of MMP9 protein]; ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA] CTD PMID:21316417 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP		 ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein] CTD PMID:21818760 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein] CTD PMID:21818760 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of and results in increased secretion of TNF protein]; ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21316417 PMID:30859215 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    chemical entity 19842
      group 19800
        inorganic group 19395
          oxo group 18890
            organic oxo compound 18890
              carbonyl compound 18890
                carboxylic acid 18631
                  oxo carboxylic acid 6314
                    Ethyl pyruvate 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19486
                              organochalcogen compound 19249
                                organooxygen compound 19167
                                  carbon oxoacid 18634
                                    carboxylic acid 18631
                                      oxo carboxylic acid 6314
                                        Ethyl pyruvate 11
paths to the root