Adipoq Rat Gene (adiponectin, C1Q and collagen domain containing)

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Keyword

Gene:
Adipoq ( Rattus norvegicus )
adiponectin, C1Q and collagen domain containing
Description: adipocyte complement-related factor that plays a role in obesity-related insulin resistance
Synonyms: Acdc; adipocyte complement related protein of 30 kDa; Acrp30;  (details...)
ArrayIDs: 5643905; 6380526; 1381997_at; 6741180; rc_AI105446_at; rc_AI176736_at; 6150645; 5628414; A_43_P13392; 6222966; A_44_P393531; 6550442; GE16606; 6653644;  (details...)
Gene Type: protein-coding

Additional Data

Curated Variants: Adipoq^m1Mcwi
Adipoq^m2Mcwi
Adipoq^m3Mcwi

Homologs
Homo sapiens: ADIPOQ     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Adipoq     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Adipoq genome assembly 3.1 11 79965888 - 79968654
Rat Celera Assembly 11 76597050 - 76599822
RGSC genome assembly v3.4 11 79908291 - 79921105
Cytogenetic 11 q23
Mus musculus Adipoq Mouse genome assembly build 36.1 16 23146609 - 23158041
Homo sapiens ADIPOQ human genome assembly 3 188043164 - 188058952
Human genome assembly build 36.2 3 188043157 - 188058946
Cytogenetic 3 q27

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Gene Ontology

hormone activity,  protein binding,  eukaryotic cell surface binding ... (details...)
Biological Process

Gene Ontology

positive regulation of fatty acid metabolic process,  negative regulation of hormone secretion,  positive regulation of cellular protein metabolic process ... (details...)
Cellular Component

Gene Ontology

extracellular space,  endoplasmic reticulum (details...)
Disease

Ontology

Diabetes Mellitus, Experimental,  Hyperinsulinemia,  Insulin Resistance ... (details...)
Phenotype

Ontology

increased mean arterial blood pressure (details...)
Pathway

Ontology

adiponectin signaling pathway (details...)
Regulation

Note Reference

expression in adipose tissue is induced by the cannabinoid receptor antagonist SR141716 632491

External Links
Databases
DATABASE ID SOURCE
SMART: C1Q IPI
PROSITE: C1Q IPI
UNIPARC: UPI00000E5D96 IPI
KEGG Report: rno:246253 ENTREZGENE
HomoloGene Group ID: 3525 ENTREZGENE
Germonline: 628748
Pfam: Collagen IPI
Pfam: C1q IPI
KEGG Pathway: 04920 ENTREZGENE
KEGG Pathway: 03320 ENTREZGENE
KEGG Pathway: 04930 ENTREZGENE
InterPro: Tumour_necrosis_fac-like. IPI
InterPro: C1q. IPI
InterPro: Collagen. IPI
Ensembl Protein: ENSRNOP00000002492 IPI
IPI: IPI00202515 IPI
Gene3D-CATH: Tumour_necrosis_fac-like IPI
Entrez Gene: Adipoq ENTREZGENE
IMAGE_CLONE: IMAGE:7308618 IMAGE-MGC_LOAD
MGC_CLONE: MGC:108583 IMAGE-MGC_LOAD
UniProt: Q8K3R4_RAT IPI
Ensembl Genes: ENSRNOG00000001821 IPI
Superfamily-SCOP: TNF_like IPI
PRINTS: COMPLEMNTC1Q. IPI
Sequences
Nucleotide: CH473999 Get FASTA Search GEO Profiles
Nucleotide: AY033885 Get FASTA Search GEO Profiles
Nucleotide: NM_144744 Get FASTA Search GEO Profiles
Nucleotide: BC092565 Get FASTA Search GEO Profiles
(View all 4 Nucleotide Accessions)
Protein: AAK61608 Get FASTA
Protein: EDL78080 Get FASTA
Protein: Q8K3R4 Get FASTA
Protein: NP_653345 Get FASTA
Protein: AAH92565 Get FASTA
(View all 5 Protein Accessions)
Clusters
UniGene: 24299

References
Curated References
26 references in RGD related to Adipoq

Other References
50 other references at PubMed related to Adipoq

Database Information
RGD ID 628748
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

30-MAR-06: Adipoq adiponectin, C1Q and collagen domain containing Acdc adipocyte complement related protein of 30 kDa APPROVED Symbol and Name updated 1299863

10-SEP-04: Acdc adipocyte complement related protein of 30 kDa Acrp30 APPROVED Symbol and Name updated 1299863

27-FEB-03: Acrp30 adipocyte complement related protein of 30 kDa PROVISIONAL Symbol and Name status set to provisional 70820