GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adipoq | multiple interactions | EXP | | 6480464 | CTD | ADIPOQ protein inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; ADIPOQ protein inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]; ADIPOQ protein inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; IL10 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]]; zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] | PMID:20052772 PMID:20861358 | Adipoq | decreases response to substance | ISO | Adipoq (Mus musculus) | 6480464 | CTD | ADIPOQ results in decreased susceptibility to Lipopolysaccharides | PMID:22156343 | Adipoq | increases expression | ISO | Adipoq (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of ADIPOQ mRNA | PMID:17641834 | Adipoq | increases secretion | ISO | Adipoq (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased secretion of ADIPOQ protein | PMID:17641834 | Adipoq | multiple interactions | ISO | ADIPOQ (Homo sapiens) | 6480464 | CTD | ADIPOQ inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] | PMID:22156343 | Adipoq | multiple interactions | ISO | Adipoq (Mus musculus) | 6480464 | CTD | ADIPOQ gene mutant form promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; ADIPOQ protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of CXCL10 mRNA]; ADIPOQ protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of IFNB1 mRNA]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of HMOX1 protein]; ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT1 protein]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]; ADIPOR2 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; ADIPOR2 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]; HMOX1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; HMOX1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased expression of ADIPOQ mRNA]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of ADIPOQ protein]; zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]] | PMID:17641834 PMID:20861358 PMID:22156343 | |
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