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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628748
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adipoqdecreases abundanceEXP 6480464CTDADIPOQ protein results in decreased abundance of TestosteronePMID:24472609
Adipoqdecreases chemical synthesisEXP 6480464CTDADIPOQ protein results in decreased chemical synthesis of TestosteronePMID:22155228
Adipoqmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of ADIPOQ mRNA; ADIPOQ protein inhibits the reaction [LHB protein results in increased chemical synthesis of Testosterone]PMID:22155228 PMID:26496021
Adipoqdecreases expressionISOADIPOQ (Homo sapiens)6480464CTDTestosterone results in decreased expression of ADIPOQPMID:16793964
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