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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628748
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adipoqincreases expressionEXP 6480464CTDQuercetin results in increased expression of ADIPOQ proteinPMID:18551111
Adipoqmultiple interactionsEXP 6480464CTD[Dietary Fats co-treated with Quercetin] affects the expression of ADIPOQ mRNA; Quercetin inhibits the reaction [Dietary Fats results in increased expression of ADIPOQ protein]PMID:20580672 PMID:24622831
Adipoqincreases expressionISOAdipoq (Mus musculus)6480464CTDQuercetin results in increased expression of ADIPOQ proteinPMID:30445784
Adipoqmultiple interactionsISOAdipoq (Mus musculus)6480464CTDQuercetin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of ADIPOQ protein]; Quercetin inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]PMID:21462320 PMID:24465016
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