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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628748 Species: Rattus norvegicus RGD Object: Gene Symbol: Adipoq Name: adiponectin, C1Q and collagen domain containing

Acc ID: CHEBI:41879 Term: dexamethasone Definition: A fluorinated steroid that has formula C22H29FO5. CasRN: 50-02-2 Chemical ID: MESH:D003907

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1552054	6480464	CTD	[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]	PMID:16054899
multiple interactions	ISO	RGD:1351472	6480464	CTD	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA rosiglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]	PMID:19186324
multiple interactions	ISO	RGD:1552054	6480464	CTD	bisphenol A inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA] Diethylhexyl Phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA] tributyltin promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]	PMID:22197818
increases expression	EXP		6480464	CTD	Dexamethasone results in increased expression of ADIPOQ mRNA	PMID:23166830
multiple interactions	ISO	RGD:1351472	6480464	CTD	[triflumizol co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with INS protein] results in increased expression of ADIPOQ mRNA [rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with INS protein] results in increased expression of ADIPOQ mRNA	PMID:23086663
multiple interactions	ISO	RGD:1552054	6480464	CTD	[rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA [triflumizol co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA	PMID:23086663
increases expression	ISO	RGD:1351472	6480464	CTD	Dexamethasone results in increased expression of ADIPOQ mRNA	PMID:19853017
multiple interactions	ISO	RGD:1552054	6480464	CTD	butylparaben promotes the reaction [Dexamethasone results in increased expression of ADIPOQ mRNA]	PMID:22956630
multiple interactions	ISO	RGD:1552054	6480464	CTD	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA sodium arsenite inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]	PMID:23152186
increases expression	ISO	RGD:1552054	6480464	CTD	Dexamethasone results in increased expression of ADIPOQ mRNA	PMID:22956630
multiple interactions	ISO	RGD:1351472	6480464	CTD	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA BQ 610 affects the reaction [sodium arsenite inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]] Pertussis Toxin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA] RES 701-1 affects the reaction [sodium arsenite inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]] sodium arsenite affects the reaction [Pertussis Toxin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]]	PMID:23152186