Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of ADIPOQ mRNA; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dietary Fats] results in increased expression of ADIPOQ protein; NR1I3 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of ADIPOQ mRNA]