| 2325 | Cdkn2c | cyclin-dependent kinase inhibitor 2C | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN oligodendrocyte differentiation; negative regulation of cell growth (ortholog); negative regulation of cell population proliferation (ortholo g); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; ASSOCIATED WITH hepatocellular carcinoma (ortholog); multiple myeloma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 129639736 | 129645564 | Rat | 241 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 735078 | Lamtor1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | ENCODES a protein that exhibits GTPase binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to nutrient levels (ortholog); cholesterol homeostasis (ortholog ); PARTICIPATES IN mTOR signaling pathway; FOUND IN late endosome membrane; membrane raft; FNIP-folliculin RagC/D GAP (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 165684001 | 165689698 | Rat | 137 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619877 | Nme2 | NME/NM23 nucleoside diphosphate kinase 2 | ENCODES a protein that exhibits enzyme binding; fatty acid binding; heterocyclic compound binding; INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to fatty acid; cellular response to glucose stimulus; PARTICIPATES IN adefovir pharmacokinetics pathway; de novo pyrimidine biosynthetic pathway; Glut1 deficiency syndrome pathway; ASSOCIATED WITH decreased metastatic potential; ASSOCIATED WITH Neoplasm Metastasis; arteriosclerosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN intermediate filament; mitochondrial membrane; perinuclear region of cytoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 10 | 79394999 | 79400418 | Rat | 256 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 621200 | Elob | elongin B | ENCODES a protein that exhibits protein-containing complex binding; transcription coactivator activity; transcription corepressor binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; target-directed miRNA degradation (ortholog); transcription initiation at RNA p olymerase II promoter (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; renal cell carcinoma pathway; ubiquitin/proteasome degradation pathway; FOUND IN transcription regulator complex; VCB complex; Cul2-RING ubiquitin ligase complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 13353413 | 13358484 | Rat | 123 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311605 | Atraid | all-trans retinoic acid-induced differentiation factor | ENCODES a protein that exhibits xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN cell differentiation (ortholog); negative regulation of osteoblast proliferation (ortholog); negative regulation of protein catabolic process (ortholog); FOUND IN lysosomal membrane (ortholog); nucl ear envelope (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; acrylamide | 6 | 31035194 | 31039779 | Rat | 66 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2992 | Stmn1 | stathmin 1 | ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN axonogenesis (ortholog); hepatocyte growth factor receptor signaling pathway (ortholog); microtubule depolymerization (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); basal cell carcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate | 5 | 151964308 | 151970843 | Rat | 354 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2203 | Bet1 | Bet1 golgi vesicular membrane trafficking protein | ENCODES a protein that exhibits syntaxin binding; INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle fusion with Golgi apparatus; ASSOCIATED WITH congenital muscular dystrophy with rapid progression (ortholog); COVID-19 (ortholog); epilepsy (ortholog); FOUND IN Golgi cis cisterna; Golgi cisterna; SNARE complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil | 4 | 33070892 | 33081162 | Rat | 115 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1594734 | Nme2-ps1 | NME/NM23 nucleoside diphosphate kinase 2, pseudogene 1 | INTERACTS WITH ammonium chloride | 20 | 11178950 | 11179551 | Rat | 1 | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1595422 | Nme2-ps7 | NME/NM23 nucleoside diphosphate kinase 2, pseudogene 7 | | 2 | 35204942 | 35207505 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1565403 | Nme2-ps8 | NME/NM23 nucleoside diphosphate kinase 2, pseudogene 8 | INTERACTS WITH methoxychlor | 8 | 108002561 | 108003149 | Rat | 1 | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1584730 | Stmnl-ps2 | stathmin like, pseudogene 2 | | 4 | 40735861 | 40736309 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 632280 | Ppp1r9a | protein phosphatase 1, regulatory subunit 9A | ENCODES a protein that exhibits actin filament binding; GTPase binding; identical protein binding; INVOLVED IN cellular response to toxic substance; excitatory postsynaptic potential; negative regulation of long-term synaptic potentiation; ASSOCIATED WITH hepatocellular carcinoma; Pain; transient ce rebral ischemia; FOUND IN actin cytoskeleton; cytoskeleton; dendrite; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 33936949 | 34258927 | Rat | 206 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1305356 | Srek1ip1 | SREK1-interacting protein 1 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); zinc ion binding (inferred); INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cyclophosphamide | 2 | 37709712 | 37733391 | Rat | 73 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2561 | Erbb2 | erb-b2 receptor tyrosine kinase 2 | ENCODES a protein that exhibits Hsp90 protein binding; protein tyrosine kinase activity; protein-containing complex binding; INVOLVED IN axon regeneration; cellular response to mechanical stimulus; ERBB2-ERBB4 signaling pathway; PARTICIPATES IN mitogen activated protein kinase signaling pathway; Ras mediated signaling pathway; altered epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH increased metastatic potential; ASSOCIATED WITH amblyopia; congestive heart failure; Diabetic Cardiomyopathies; FOUND IN apical plasma membrane; basal plasma membrane; basolateral plasma membrane; INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene | 10 | 83907491 | 83931365 | Rat | 728 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2015 | Acsl1 | acyl-CoA synthetase long-chain family member 1 | ENCODES a protein that exhibits arachidonate-CoA ligase activity; long-chain fatty acid-CoA ligase activity; oleoyl-CoA ligase activity; INVOLVED IN fatty acid metabolic process; fatty acid transport; long-chain fatty acid import into cell; PARTICIPATES IN adrenoleukodystrophy pathway; carnitine pal mitoyltransferase I deficiency pathway; carnitine-acylcarnitine translocase deficiency; ASSOCIATED WITH obesity; Starvation; Animal Mammary Neoplasms (ortholog); FOUND IN mitochondrial outer membrane; mitochondrion; peroxisomal membrane; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate | 16 | 52487870 | 52554110 | Rat | 520 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2059 | Adrb1 | adrenoceptor beta 1 | ENCODES a protein that exhibits amine binding; beta1-adrenergic receptor activity; alpha-2A adrenergic receptor binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway; glycogen catabolic process; inhibitory postsynaptic potential; PARTICIPATES IN Rho/Rac/Cdc42 mediated signalin g pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH Anaphylaxis; congestive heart failure; dilated cardiomyopathy; FOUND IN plasma membrane; early endosome (ortholog); membrane (ortholog); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 3',5'-cyclic AMP | 1 | 265777103 | 265780114 | Rat | 424 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 71015 | Ap2a2 | adaptor related protein complex 2 subunit alpha 2 | ENCODES a protein that exhibits phosphatidylinositol binding; protein serine/threonine kinase binding; protein-containing complex binding; INVOLVED IN clathrin-dependent endocytosis (ortholog); synaptic vesicle endocytosis (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; Huntington's disease pathway; FOUND IN AP-2 adaptor complex; synapse; synaptic vesicle; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 206081856 | 206155146 | Rat | 155 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1593158 | Arhgap39 | Rho GTPase activating protein 39 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN postsynapse organization (ortholog); FOUND IN glutamatergic synapse; postsynapse; INTERACTS WITH 2,6-dinitrotoluene; alpha-Zearalanol; amitrole | 7 | 110326918 | 110419500 | Rat | 62 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2175 | Atp2a3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 | ENCODES a protein that exhibits calcium ion transmembrane transporter activity; calcium-dependent ATPase activity; P-type calcium transporter activity; INVOLVED IN calcium ion transmembrane transport; endoplasmic reticulum calcium ion homeostasis; liver regeneration; PARTICIPATES IN calcium transpor t pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; hypertension; adenoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); organelle membrane (ortholog); sarcoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil | 10 | 58079710 | 58111279 | Rat | 192 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2178 | Atp4b | ATPase H+/K+ transporting subunit beta | ENCODES a protein that exhibits heterocyclic compound binding; INVOLVED IN pH reduction; response to lipopolysaccharide; potassium ion transmembrane transport (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway ; ASSOCIATED WITH Experimental Diabetes Mellitus; obesity; atrophic gastritis (ortholog); FOUND IN potassium:proton exchanging ATPase complex (ortholog); INTERACTS WITH ammonium chloride; atrazine; bisphenol A | 16 | 82846329 | 82855242 | Rat | 79 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620288 | Calr | calreticulin | ENCODES a protein that exhibits calcium ion binding; hormone binding; iron ion binding; INVOLVED IN cardiac muscle cell differentiation; cellular response to electrical stimulus; cellular response to lithium ion; PARTICIPATES IN calcium/calcium-mediated signaling pathway; antigen processing and pres entation pathway; Chagas disease pathway; ASSOCIATED WITH Fibrosis; vitamin B12 deficiency; acute myeloid leukemia (ortholog); FOUND IN acrosomal vesicle; cell surface; endoplasmic reticulum; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,2,2-tetramine | 19 | 40213367 | 40218262 | Rat | 554 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2354 | Chrng | cholinergic receptor nicotinic gamma subunit | ENCODES a protein that exhibits acetylcholine-gated monoatomic cation-selective channel activity; ligand-gated monoatomic ion channel activity; INVOLVED IN monoatomic cation transport; skeletal muscle contraction; regulation of membrane potential (ortholog); PARTICIPATES IN acetylcholine signaling p athway via nicotinic acetylcholine receptor; ASSOCIATED WITH arthrogryposis multiplex congenita (ortholog); bone development disease (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN acetylcholine-gated channel complex; plasma membrane (ortholog); postsynaptic membrane (ortholog); INTERACTS WITH acetylcholine; acrylamide; ammonium chloride | 9 | 95325984 | 95332092 | Rat | 102 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2398 | Cpt2 | carnitine palmitoyltransferase 2 | ENCODES a protein that exhibits carnitine O-palmitoyltransferase activity; acyltransferase activity (ortholog); INVOLVED IN fatty acid beta-oxidation; response to fatty acid; carnitine metabolic process (ortholog); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine palmitoyltransferase I defici ency pathway; carnitine-acylcarnitine translocase deficiency; ASSOCIATED WITH brain disease (ortholog); carnitine palmitoyltransferase II deficiency (ortholog); Carnitine Palmitoyltransferase II Deficiency, Infantile (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (R)-carnitine; 17beta-estradiol; 2,2,2-tetramine | 5 | 127893450 | 127911347 | Rat | 392 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 619726 | Csde1 | cold shock domain containing E1 | ENCODES a protein that exhibits lncRNA binding (ortholog); RISC complex binding (ortholog); RNA stem-loop binding (ortholog); INVOLVED IN CRD-mediated mRNA stabilization (ortholog); IRES-dependent viral translational initiation (ortholog); negative regulation of nuclear-transcribed mRNA catabolic pr ocess, deadenylation-dependent decay (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 11 (ortholog); genetic disease (ortholog); FOUND IN CRD-mediated mRNA stability complex (ortholog); cytosol (ortholog); mCRD-mediated mRNA stability complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 193234546 | 193271301 | Rat | 136 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2443 | Cth | cystathionine gamma-lyase | ENCODES a protein that exhibits cystathionine gamma-lyase activity (ortholog); identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN glutathione metabolic process; negative regulation of cell growth; negative regulation of cell population pro liferation; PARTICIPATES IN cystathioninuria pathway; cysteine metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; ASSOCIATED WITH cataract; amino acid metabolic disorder (ortholog); cystathioninuria (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine | 2 | 249634731 | 249661066 | Rat | 429 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2482 | Cyp7a1 | cytochrome P450 family 7 subfamily A member 1 | ENCODES a protein that exhibits cholesterol 7-alpha-monooxygenase activity; INVOLVED IN bile acid biosynthetic process; cellular response to cholesterol; cholesterol catabolic process; PARTICIPATES IN bile acid biosynthetic pathway; bile acid signaling pathway; cerebrotendinous xanthomatosis pathway ; ASSOCIATED WITH alcoholic hepatitis; cholestasis; Experimental Liver Cirrhosis; FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (25R)-cholest-5-ene-3beta,26-diol | 5 | 24174505 | 24184202 | Rat | 655 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68418 | Dio2 | iodothyronine deiodinase 2 | ENCODES a protein that exhibits thyroxine 5'-deiodinase activity; thyroxine 5-deiodinase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN response to lipopolysaccharide; thyroid hormone generation; thyroid hormone metabolic process; ASSOCIATED WITH autism spectrum disord er (ortholog); basal cell carcinoma (ortholog); endometriosis (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol | 6 | 115396308 | 115410594 | Rat | 322 | UniProt , old_protein_id | gene, protein-coding, REVIEWED [RefSeq] |
| 2518 | Drd1 | dopamine receptor D1 | ENCODES a protein that exhibits angiotensin receptor binding; ATPase binding; D3 dopamine receptor binding; INVOLVED IN adenylate cyclase-activating dopamine receptor signaling pathway; associative learning; behavioral response to cocaine; PARTICIPATES IN dopamine signaling pathway; alfentanil pharm acodynamics pathway; bupivacaine pharmacodynamics pathway; ASSOCIATED WITH abnormal response to social novelty; abnormal social investigation; abnormal vocalization; ASSOCIATED WITH alcohol dependence; Binge Drinking; Binge-Eating Disorder; FOUND IN axon; axon terminus; caveola; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-nicotine | 17 | 10545488 | 10550029 | Rat | 541 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 61996 | F2 | coagulation factor II, thrombin | ENCODES a protein that exhibits endopeptidase activity (ortholog); heparin binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN cellular response to mechanical stimulus; positive regulation of blood coagulation; response to inactivity; PARTICIPATES IN coagulation cascade pathway; a cenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; ASSOCIATED WITH Acute Lung Injury; atherosclerosis; bacterial pneumonia; FOUND IN extracellular matrix; extracellular space; external side of plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17beta-estradiol | 3 | 98051958 | 98065246 | Rat | 588 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2630 | Fshb | follicle stimulating hormone subunit beta | ENCODES a protein that exhibits follicle-stimulating hormone activity (ortholog); INVOLVED IN follicle-stimulating hormone signaling pathway (ortholog); G protein-coupled receptor signaling pathway (ortholog); ovarian follicle development (ortholog); PARTICIPATES IN follicle-stimulating hormone sign aling pathway; gonadotropin-releasing hormone signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); amenorrhea (ortholog); Female Infertility (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); follicle-stimulating hormone complex (ortholog); INTERACTS WITH (+)-artemisinin; (+)-pilocarpine; (+)-taxifolin | 3 | 114003262 | 114007072 | Rat | 557 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 61855 | Gabra1 | gamma-aminobutyric acid type A receptor subunit alpha 1 | ENCODES a protein that exhibits diazepam binding; GABA receptor activity; GABA-A receptor activity; INVOLVED IN cellular response to histamine; response to auditory stimulus; response to methamphetamine hydrochloride; ASSOCIATED WITH Binge Drinking; Hearing Loss, Noise-Induced; hepatic encephalopath y; FOUND IN GABA receptor complex; GABA-ergic synapse; postsynaptic specialization membrane; INTERACTS WITH (+)-pilocarpine; 1-bromopropane; 17beta-estradiol | 10 | 27096731 | 27152563 | Rat | 329 | old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61901 | Gabrd | gamma-aminobutyric acid type A receptor subunit delta | ENCODES a protein that exhibits GABA-A receptor activity; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN chemical synaptic transmission; chloride transmembrane transport (ortholog); gamma-aminobutyric acid signaling pathway (ortholog); ASSOCIATED WITH alcohol dependence; cocaine dependence; autism spectrum disorder (ortholog); FOUND IN GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; INTERACTS WITH (+)-pilocarpine; 1,3,5-trinitro-1,3,5-triazinane; 3alpha-hydroxy-5beta-pregnan-20-one | 5 | 171240813 | 171252709 | Rat | 152 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61966 | Gabrg2 | gamma-aminobutyric acid type A receptor subunit gamma 2 | ENCODES a protein that exhibits chloride channel activity; GABA receptor activity; GABA-A receptor activity; INVOLVED IN cellular response to zinc ion; chloride transport; response to anesthetic; ASSOCIATED WITH alcohol withdrawal syndrome; fetal alcohol spectrum disorder; hepatic encephalopathy; FO UND IN cell surface; dendrite membrane; GABA receptor complex; INTERACTS WITH 1-bromopropane; 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one | 10 | 26876926 | 26965523 | Rat | 324 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2652 | Gad1 | glutamate decarboxylase 1 | ENCODES a protein that exhibits glutamate binding; glutamate decarboxylase activity; protein-containing complex binding; INVOLVED IN cellular response to hypoxia; cellular response to serotonin; gamma-aminobutyric acid biosynthetic process; PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; beta-al anine metabolic pathway; Canavan disease pathway; ASSOCIATED WITH abnormal response to novel object; abnormal spike wave discharge; behavioral despair; ASSOCIATED WITH anxiety disorder; autism spectrum disorder; diabetes mellitus; FOUND IN neuronal cell body; presynaptic active zone; axon (ortholog); INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (R)-lipoic acid | 3 | 75777260 | 75818099 | Rat | 385 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621493 | Gale | UDP-galactose-4-epimerase | ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); UDP-glucose 4-epimerase activity (ortholog); INVOLVED IN galactose catabolic process (ortholog); galactose metabolic process (ortholog); PARTICIPATES IN galactokinase deficiency pathwa y; galactose metabolic pathway; galactosemia pathway; ASSOCIATED WITH galactose epimerase deficiency (ortholog); galactosemia (ortholog); genetic disease (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 5 | 153477420 | 153481926 | Rat | 174 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620351 | Gsk3a | glycogen synthase kinase 3 alpha | ENCODES a protein that exhibits protein kinase A catalytic subunit binding; protein kinase binding; protein serine/threonine kinase activity; INVOLVED IN negative regulation of dendrite development; negative regulation of insulin receptor signaling pathway; positive regulation of neuron apoptotic pr ocess; PARTICIPATES IN glycogen biosynthetic pathway; nuclear factor, erythroid 2 like 2 signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Parkinsonism; Alzheimer's disease (ortholog); FOUND IN microtubule; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide | 1 | 89943669 | 89953514 | Rat | 265 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 70982 | Gsk3b | glycogen synthase kinase 3 beta | ENCODES a protein that exhibits ATP binding; integrin binding; ionotropic glutamate receptor binding; INVOLVED IN bone remodeling; cell growth involved in cardiac muscle cell development; cellular response to amyloid-beta; PARTICIPATES IN long term depression; Wnt signaling, canonical pathway; Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH neurodegeneration; ASSOCIATED WITH Aberrant Crypt Foci; acute myocardial infarction; Alzheimer's disease; FOUND IN axon; beta-catenin destruction complex; dendrite; INTERACTS WITH (R)-lipoic acid; (R)-salsolinol; (S)-colchicine | 11 | 76004502 | 76154665 | Rat | 1536 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620018 | Gzmb | granzyme B | ENCODES a protein that exhibits serine-type endopeptidase activity; serine-type peptidase activity; INVOLVED IN neuron apoptotic process; positive regulation of necroptotic process; defense response to bacterium (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; allograft rejection pathwa y; autoimmune thyroiditis pathway; ASSOCIATED WITH brain infarction; Acute Lung Injury (ortholog); autistic disorder (ortholog); FOUND IN early endosome; cytolytic granule (ortholog); cytoplasm (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17beta-estradiol; 17beta-estradiol 3-benzoate | 15 | 34459007 | 34462469 | Rat | 194 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 620649 | Hmgn2 | high mobility group nucleosomal binding domain 2 | ENCODES a protein that exhibits DNA binding (inferred); nucleosomal DNA binding (inferred); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of development, heterochronic ( ortholog); ASSOCIATED WITH Axenfeld-Rieger syndrome type 1 (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); nucleolus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 5 | 151475907 | 151479361 | Rat | 141 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1559918 | Hoxb7 | homeo box B7 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic or gan development (ortholog); embryonic skeletal system morphogenesis (ortholog); ASSOCIATED WITH esophagus squamous cell carcinoma (ortholog); hereditary breast ovarian cancer syndrome (ortholog); invasive ductal carcinoma (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 81749159 | 81752577 | Rat | 114 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1586211 | Hoxb8 | homeo box B8 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specif ication (ortholog); dorsal spinal cord development (ortholog); ASSOCIATED WITH obsessive-compulsive disorder (ortholog); trichotillomania (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; Butylbenzyl phthalate | 10 | 81745430 | 81747181 | Rat | 79 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1586210 | Hoxc4 | homeo box C4 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); HMG box domain binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to glial cell derived neurotrophic f actor; positive regulation of male germ-line stem cell asymmetric division; anterior/posterior pattern specification (ortholog); ASSOCIATED WITH esophageal atresia (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride | 7 | 136049059 | 136051601 | Rat | 90 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2821 | Hoxc8 | homeobox C8 | ENCODES a protein that exhibits DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); neuron differentiation (ortholog); FOUND IN nucleop lasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; ammonium chloride | 7 | 136006407 | 136008973 | Rat | 67 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1595784 | Hoxc9 | homeobox C9 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic skeletal system development (ortholog); embryonic skeletal system morphogenesis (ortholog); FOUND IN nucleoplasm (ortholog); transcript ion repressor complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; atrazine | 7 | 135997292 | 135999969 | Rat | 73 | old_protein_id | gene, protein-coding, VALIDATED [RefSeq] |
| 1588601 | Hoxd3 | homeo box D3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pa ttern specification (ortholog); cartilage development (ortholog); cell-matrix adhesion (ortholog); ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride | 3 | 80041598 | 80057700 | Rat | 110 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 62074 | Inhba | inhibin subunit beta A | ENCODES a protein that exhibits protein-containing complex binding; cytokine activity (ortholog); identical protein binding (ortholog); INVOLVED IN autophagy; cardiac fibroblast cell development; cellular response to angiotensin; PARTICIPATES IN transforming growth factor-beta superfamily mediated s ignaling pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; congestive heart failure; myocardial infarction; FOUND IN extracellular space; inhibin A complex; activin A complex (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 17 | 53787159 | 53810942 | Rat | 479 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2923 | Itga1 | integrin subunit alpha 1 | ENCODES a protein that exhibits collagen binding; signaling receptor binding; collagen binding involved in cell-matrix adhesion (ortholog); INVOLVED IN cell chemotaxis; neuron projection morphogenesis; positive regulation of MAPK cascade; PARTICIPATES IN altered integrin mediated signaling pathway; myocardial infarction pathway; integrin mediated signaling pathway; ASSOCIATED WITH Hyperalgesia; arteriosclerosis (ortholog); breast cancer (ortholog); FOUND IN acrosomal vesicle; external side of plasma membrane; perikaryon; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 17beta-estradiol | 2 | 48379181 | 48545336 | Rat | 220 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2993 | Lcat | lecithin cholesterol acyltransferase | ENCODES a protein that exhibits A2-type glycerophospholipase activity; phosphatidylcholine-sterol O-acyltransferase activity; 1-alkyl-2-acetylglycerophosphocholine esterase activity (ortholog); INVOLVED IN cholesterol metabolic process; lipoprotein metabolic process; response to copper ion; PARTICIP ATES IN reverse cholesterol transport pathway; glycerophospholipid metabolic pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; end stage renal disease; familial hyperlipidemia; FOUND IN extracellular space (ortholog); high-density lipoprotein particle (ortholog); INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (R,R,R)-alpha-tocopherol | 19 | 50744598 | 50748064 | Rat | 282 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 2321223 | LOC100364335 | cold shock domain-containing protein E1-like | ENCODES a pseudogene that exhibits nucleic acid binding (inferred); RNA binding (inferred); FOUND IN cytoplasmic stress granule (inferred); P-body (inferred) | 19 | 29652535 | 29656308 | Rat | 4 | old_protein_id | gene, pseudo, INFERRED [RefSeq] |
| 619985 | Mat2a | methionine adenosyltransferase 2A | ENCODES a protein that exhibits amino acid binding; ATP binding; methionine adenosyltransferase activity; INVOLVED IN circadian rhythm; response to cAMP; response to hormone; PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; ASSOCIATED WITH fetal alcohol spectrum disorder; Prenatal Exposure Delayed Effects; coronary artery disease (ortholog); FOUND IN methionine adenosyltransferase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 106048043 | 106053612 | Rat | 265 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306391 | Mrpl3 | mitochondrial ribosomal protein L3 | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN translation (inferred); ASSOCIATED WITH brain disease (ortholog); combined oxidative phosphorylation deficiency 9 (ortholog); FOUND IN mitochondrial large ribosomal subunit (ortholog); mitochondrion (ortholog) ; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide | 8 | 114548970 | 114572330 | Rat | 83 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3127 | Mx1 | MX dynamin like GTPase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN response to virus; antiviral innate immune response (ortholog); innate immune response (ortholog); ASSOCIATED WITH Chronic Hepatitis C; acute myeloid leukemia (ortholog); alopecia areata (ortholog); FOUND IN nucleus; c ytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 11 | 50269056 | 50294699 | Rat | 306 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 628821 | Mx2 | MX dynamin like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN response to virus; cellular response to type I interferon (ortholog); defense response to virus (ortholog); PARTICIPATES IN influenza A pathway; measles pathway; ASSOCIATED WITH Human Influenza (ortholog) ; melanoma (ortholog); FOUND IN cytoplasm; exocytic vesicle (ortholog); nuclear pore (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 11 | 50375101 | 50399373 | Rat | 173 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628855 | Myl12b | myosin light chain 12B | ENCODES a protein that exhibits GTPase binding (ortholog); myosin heavy chain binding (ortholog); INVOLVED IN regulation of cell shape (ortholog); FOUND IN protein-containing complex; apical part of cell (ortholog); brush border (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 118320479 | 118334810 | Rat | 117 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 70976 | Nfya | nuclear transcription factor Y subunit alpha | ENCODES a protein that exhibits transcription coregulator binding; transcription factor binding; DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of stem cell proliferation (ortholog); positive regulation of transcription by RNA p olymerase II (ortholog); PARTICIPATES IN altered p53 signaling pathway; antigen processing and presentation pathway; tuberculosis pathway; ASSOCIATED WITH Lung Neoplasms (ortholog); FOUND IN CCAAT-binding factor complex; nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 9 | 20085067 | 20111521 | Rat | 157 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3195 | Npr1 | natriuretic peptide receptor 1 | ENCODES a protein that exhibits guanylate cyclase activity; hormone binding (ortholog); natriuretic peptide receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway; dopamine metabolic process; intracellular signal transduction; PARTICIPATES IN purine metabolic pathway; ASSO CIATED WITH increased systemic arterial blood pressure; increased systemic arterial diastolic blood pressure; ASSOCIATED WITH hypertension; Left Ventricular Hypertrophy; Aortic Rupture (ortholog); FOUND IN ANPR-A receptor complex; endoplasmic reticulum membrane; nuclear membrane; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 178231766 | 178247591 | Rat | 154 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619728 | Ntf3 | neurotrophin 3 | ENCODES a protein that exhibits nerve growth factor binding; chemoattractant activity (ortholog); growth factor activity (ortholog); INVOLVED IN modulation of chemical synaptic transmission; myelination; nervous system development; PARTICIPATES IN mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; ASSOCIATED WITH alcohol use disorder; Alcohol-Related Disorders; borna disease; FOUND IN cytoplasmic vesicle (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-adrenaline; (R)-noradrenaline | 4 | 160601161 | 160670623 | Rat | 250 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3372 | Ppia | peptidylprolyl isomerase A | ENCODES a protein that exhibits cyclosporin A binding; heparan sulfate binding (ortholog); integrin binding (ortholog); INVOLVED IN negative regulation of calcineurin-mediated signaling; activation of protein kinase B activity (ortholog); apoptotic process (ortholog); ASSOCIATED WITH epilepsy; aggre ssive periodontitis (ortholog); atopic dermatitis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 14 | 85491223 | 85496884 | Rat | 274 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2321083 | Ppial4d | peptidylprolyl isomerase A (cyclophilin A)-like 4D | ENCODES a protein that exhibits heparan sulfate binding (ortholog); integrin binding (ortholog); peptidyl-prolyl cis-trans isomerase activity (ortholog); INVOLVED IN activation of protein kinase B activity (ortholog); apoptotic process (ortholog); cell adhesion molecule production (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 14 | 21361379 | 21362147 | Rat | 44 | UniProt , old_protein_id | gene, protein-coding, MODEL [RefSeq] |
| 61841 | Psma1 | proteasome 20S subunit alpha 1 | ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); PARTICIPAT ES IN ubiquitin/proteasome degradation pathway; FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-bromopropane; 2,4-dinitrotoluene; 2-nitrofluorene | 1 | 177876838 | 177887857 | Rat | 195 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61844 | Psma3 | proteasome 20S subunit alpha 3 | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); PARTICIPATES IN ubi quitin/proteasome degradation pathway; ASSOCIATED WITH proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); proteasome complex (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 1,3-dinitrobenzene; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 6 | 95219714 | 95239745 | Rat | 151 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621092 | Psmb1 | proteasome 20S subunit beta 1 | INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); regulation of proteasomal protein catabolic process (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Acute Coronary Syndrom e (ortholog); Desbuquois dysplasia (ortholog); NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, HYPOTONIA, AND ABSENT LANGUAGE (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dinitrobenzene; 17alpha-ethynylestradiol | 1 | 65115770 | 65136516 | Rat | 187 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309771 | Rpl27a | ribosomal protein L27A | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN cytoplasmic translation (ortholog); translation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Animal Disease Models (ortholog); cerebellar ataxia (ortholog); Hyp erpigmentation (ortholog); FOUND IN cytosolic large ribosomal subunit; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 172971957 | 172977591 | Rat | 155 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1593282 | RT1-Db1 | RT1 class II, locus Db1 | ENCODES a protein that exhibits CD4 receptor binding (ortholog); peptide antigen binding (ortholog); polysaccharide binding (ortholog); INVOLVED IN response to dexamethasone; antigen processing and presentation of endogenous peptide antigen via MHC class II (ortholog); antigen processing and present ation of exogenous peptide antigen via MHC class II (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; allograft rejection pathway; antigen processing and presentation pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; Pneumocystis Infections; abdominal aortic aneurysm (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); immunological synapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 20 | 4550594 | 4560182 | Rat | 475 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3753 | Spr | sepiapterin reductase | ENCODES a protein that exhibits sepiapterin reductase (NADP+) activity; protein homodimerization activity (ortholog); INVOLVED IN positive regulation of cell population proliferation; tetrahydrobiopterin biosynthetic process; cell morphogenesis involved in neuron differentiation (ortholog); PARTICIP ATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; folate metabolic pathway; ASSOCIATED WITH COVID-19 (ortholog); Desbuquois dysplasia (ortholog); DOPA-responsive dystonia (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione | 4 | 119229447 | 119233320 | Rat | 137 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3858 | Thrb | thyroid hormone receptor beta | ENCODES a protein that exhibits double-stranded DNA binding; identical protein binding; nuclear receptor activity; INVOLVED IN embryonic organ development; positive regulation of cell population proliferation; positive regulation of chondrocyte differentiation; ASSOCIATED WITH breast cancer; Left Ve ntricular Hypertrophy; atrial fibrillation (ortholog); FOUND IN nuclear body (ortholog); nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl | 15 | 10115954 | 10465231 | Rat | 459 | UniProt , old_protein_id , GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3898 | Tpm1 | tropomyosin 1 | ENCODES a protein that exhibits actin binding; actin filament binding; disordered domain specific binding; INVOLVED IN actin filament capping; cardiac muscle contraction; muscle filament sliding; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker p harmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH atrial heart septal defect 1 (ortholog); cardiomyopathy (ortholog); catecholaminergic polymorphic ventricular tachycardia 1 (ortholog); FOUND IN actin cytoskeleton; protein-containing complex; bleb (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate | 8 | 76516654 | 76543661 | Rat | 424 | UniProt , old_protein_id , UniProt Secondary | gene, protein-coding, REVIEWED [RefSeq] |
| 619919 | Arid4b | AT-rich interaction domain 4B | ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN chromatin organization (ortholog); establishment of Sertoli cell barrier (ortholog); genomic imprinting (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachloro dibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 17 | 55833908 | 55958382 | Rat | 107 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 621816 | Pola1 | DNA polymerase alpha 1, catalytic subunit | ENCODES a protein that exhibits DNA-directed DNA polymerase activity; double-stranded DNA binding; purine nucleotide binding; INVOLVED IN DNA biosynthetic process; DNA replication; DNA repair (ortholog); PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; ASSOCIATED WITH aplastic anemia (ortholog); genetic disease (ortholog); Van Esch-O'Driscoll syndrome (ortholog); FOUND IN alpha DNA polymerase:primase complex; chromatin (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; aphidicolin | X | 62028475 | 62342455 | Rat | 264 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |