Gene: Gad1 (glutamate decarboxylase 1) Rattus norvegicus
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Symbol: Gad1
Name: glutamate decarboxylase 1
Description: ENCODES a protein that exhibits glutamate binding; glutamate decarboxylase activity; protein heterodimerization activity; INVOLVED IN gamma-aminobutyric acid biosynthetic process; response to drug; locomotory exploration behavior (ortholog); PARTICIPATES IN 2-hydroxyglutaricaciduria disease pathway; beta-alanine metabolic pathway; Canavan disease pathway; ASSOCIATED WITH Diabetes Mellitus; diabetes mellitus; anxiety disorder (ortholog); FOUND IN presynaptic active zone; axon (ortholog); axon terminus (ortholog); INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (RS)-amphetamine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 67 kDa glutamic acid decarboxylase; GAD-67; Gad67; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; glutamic acid decarboxylase 1
Orthologs:
Homo sapiens (human) : GAD1 (glutamate decarboxylase 1)  HGNC  AGR
Mus musculus (house mouse) : Gad1 (glutamate decarboxylase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gad1 (glutamate decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GAD1 (glutamate decarboxylase 1)
Canis lupus familiaris (dog) : GAD1 (glutamate decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gad1 (glutamate decarboxylase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0356,861,440 - 56,902,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0363,479,963 - 63,519,879 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4352,789,370 - 52,830,038 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1352,685,741 - 52,726,408 (+)NCBI
Celera354,926,942 - 54,967,478 (+)NCBICelera
Cytogenetic Map3q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gad1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2652
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE