Gene: Gad1 (glutamate decarboxylase 1) Rattus norvegicus
Symbol: Gad1
Name: glutamate decarboxylase 1
Description: ENCODES a protein that exhibits glutamate binding; glutamate decarboxylase activity; protein heterodimerization activity; INVOLVED IN gamma-aminobutyric acid biosynthetic process; response to drug; locomotory exploration behavior (ortholog); PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; beta-alanine metabolic pathway; butanoate metabolic pathway; ASSOCIATED WITH Diabetes Mellitus; Anxiety Disorders (ortholog); Bipolar Disorder (ortholog); FOUND IN presynaptic active zone; axon (ortholog); axon terminus (ortholog); INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-nicotine
Type: protein-coding
Also known as: 67 kDa glutamic acid decarboxylase; GAD-67; Gad67; Glutamate decarboxylase 1 (brain); glutamate decarboxylase 1 variant GAD67NT; glutamate decarboxylase 67 kDa isoform; glutamic acid decarboxylase 1
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0356,861,440 - 56,902,139+NCBI
Rat Cytogenetic Map3q21 NCBI
RGSC Genome Assembly v5.0363,479,963 - 63,519,879+NCBI
RGSC Genome Assembly v3.4352,789,370 - 52,830,038+NCBI
Rat Celera Assembly354,926,942 - 54,967,478+NCBI
Genome Assembly 3.1352,685,741 - 52,726,408+NCBI

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References - curated
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Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gad1
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RGD Object Information
RGD ID: 2652
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE