Myl12b (myosin light chain 12B) - Rat Genome Database

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Gene: Myl12b (myosin light chain 12B) Rattus norvegicus
Analyze
Symbol: Myl12b
Name: myosin light chain 12B
RGD ID: 628855
Description: Predicted to enable GTPase binding activity and myosin heavy chain binding activity. Predicted to act upstream of or within regulation of cell shape. Part of protein-containing complex. Orthologous to several human genes including MYL12B (myosin light chain 12B); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC114341; MLC-2; MLC20; Mrlc2; Mrlcb; Mylc2b; myosin light chain, regulatory B; myosin regulatory light chain; myosin regulatory light chain 12B; myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain MRLC2; myosin regulatory light chain-B; myosin RLC-B; myosin, light chain 12B, regulatory
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Vetf6
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,320,479 - 118,334,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9118,320,489 - 118,324,418 (-)EnsemblGRCr8
mRatBN7.29110,873,855 - 110,888,187 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx9119,261,365 - 119,275,700 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09124,390,953 - 124,405,288 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09122,727,332 - 122,741,665 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd9121,908,708 - 121,923,054 (-)NCBI
Lyon_Normotensive9117,757,364 - 117,771,705 (-)NCBI
Lyon_Hypertensive9117,885,333 - 117,899,666 (-)NCBI
F344_StmMcwi9119,862,815 - 119,877,148 (-)NCBI
Rnor_6.09119,307,168 - 119,321,500 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,307,176 - 119,321,500 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.09118,761,452 - 118,775,834 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49110,171,418 - 110,186,248 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9108,004,122 - 108,018,394 (-)NCBICelera
RGSC_v3.19110,380,900 - 110,384,839 (-)NCBI
Cytogenetic Map9q38NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiloride  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bleomycin A2  (EXP)
bucladesine  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
flavonoids  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fructose  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP)
medroxyprogesterone acetate  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
apical part of cell  (IEA,ISO)
brush border  (IEA,ISO)
cell cortex  (IEA,ISO,ISS)
cytoplasm  (IBA)
myofibril  (IBA)
myosin II complex  (IBA,IEA,ISO)
protein-containing complex  (IDA)
stress fiber  (IBA,IEA,ISO)
Z disc  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mammalian nonsarcomeric myosin regulatory light chains are encoded by two differentially regulated and linked genes. Grant JW, etal., J Cell Biol 1990 Sep;111(3):1127-35.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Identification of a multiprotein "motor" complex binding to water channel aquaporin-2. Noda Y, etal., Biochem Biophys Res Commun. 2005 May 20;330(4):1041-7.
5. Molecular cloning of a unique complementary DNA of rat myosin regulatory light chain and its elevated expression in v-src-transformed rat culture cell lines. Ozaki T, etal., Cell Growth Differ 1993 Nov;4(11):939-45.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Cloning and characterization of mammalian myosin regulatory light chain (RLC) cDNA: the RLC gene is expressed in smooth, sarcomeric, and nonmuscle tissues. Taubman MB, etal., J Cell Biol 1987 Jun;104(6):1505-13.
Additional References at PubMed
PMID:1649372   PMID:8034049   PMID:12970723   PMID:15037549   PMID:15277470   PMID:15489334   PMID:17543276   PMID:20458337   PMID:21126233   PMID:22114352   PMID:22661704   PMID:23870127  
PMID:24625528   PMID:24825904   PMID:25002582   PMID:27233767   PMID:35352799  


Genomics

Comparative Map Data
Myl12b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,320,479 - 118,334,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9118,320,489 - 118,324,418 (-)EnsemblGRCr8
mRatBN7.29110,873,855 - 110,888,187 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx9119,261,365 - 119,275,700 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09124,390,953 - 124,405,288 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09122,727,332 - 122,741,665 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd9121,908,708 - 121,923,054 (-)NCBI
Lyon_Normotensive9117,757,364 - 117,771,705 (-)NCBI
Lyon_Hypertensive9117,885,333 - 117,899,666 (-)NCBI
F344_StmMcwi9119,862,815 - 119,877,148 (-)NCBI
Rnor_6.09119,307,168 - 119,321,500 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,307,176 - 119,321,500 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.09118,761,452 - 118,775,834 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.49110,171,418 - 110,186,248 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera9108,004,122 - 108,018,394 (-)NCBICelera
RGSC_v3.19110,380,900 - 110,384,839 (-)NCBI
Cytogenetic Map9q38NCBI
MYL12B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38183,262,133 - 3,278,461 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl183,261,479 - 3,278,461 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37183,262,131 - 3,278,459 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36183,252,135 - 3,268,179 (+)NCBIBuild 36Build 36hg18NCBI36
Celera183,141,594 - 3,157,815 (+)NCBICelera
Cytogenetic Map18p11.31NCBI
HuRef183,226,523 - 3,243,194 (+)NCBIHuRef
CHM1_1183,261,491 - 3,277,645 (+)NCBICHM1_1
T2T-CHM13v2.0183,421,438 - 3,437,816 (+)NCBIT2T-CHM13v2.0
Myl12b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,280,958 - 71,297,511 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,280,119 - 71,297,959 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381770,973,963 - 70,990,516 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1770,973,133 - 70,990,890 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371771,323,303 - 71,339,856 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361770,878,820 - 70,895,373 (-)NCBIMGSCv36mm8
Celera1775,244,495 - 75,261,050 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
MYL12B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21735,162,868 - 35,179,082 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11820,855,526 - 20,871,861 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01810,999,849 - 11,016,059 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11813,308,356 - 13,324,754 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1813,308,356 - 13,324,754 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
MYL12B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1769,877,727 - 69,895,196 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha769,332,485 - 69,350,491 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0769,938,422 - 69,954,234 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl769,939,041 - 69,957,106 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1769,621,752 - 69,639,768 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0769,640,728 - 69,658,745 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0769,939,371 - 69,957,614 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101966654
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11351,255,712 - 51,273,974 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440494466,219,949 - 66,238,423 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366721,300,341 - 1,322,065 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366721,303,510 - 1,321,969 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC733637
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6103,409,717 - 103,420,286 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.16103,413,841 - 103,424,790 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2696,440,639 - 96,451,618 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103222701
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap11864,943,836 - 64,961,143 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605037,373,059 - 37,390,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.11862,510,012 - 62,527,027 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1862,521,295 - 62,529,131 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Myl12b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477013,378,668 - 13,408,633 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_00462477013,393,106 - 13,409,139 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla_female_1.0 EnsemblNW_00462477013,386,194 - 13,392,928 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl1860,025,081 - 60,030,727 (+)Ensembl
Naked mole-rat maternal Ensembl1860,006,176 - 60,011,788 (+)Ensembl

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:336
Count of miRNA genes:166
Interacting mature miRNAs:179
Transcripts:ENSRNOT00000048125
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
277 156 730 1591 4065 1010 1727 133 873 496 855 156 5397 2598 449 3978 38 1393 741 909 160 158

Sequence


Ensembl Acc Id: ENSRNOT00000048125   ⟹   ENSRNOP00000045992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9118,320,489 - 118,324,418 (-)Ensembl
Rnor_6.0 Ensembl9119,307,176 - 119,321,500 (-)Ensembl
RefSeq Acc Id: NM_017343   ⟹   NP_059039
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,320,479 - 118,334,810 (-)NCBI
mRatBN7.29110,873,855 - 110,888,187 (-)NCBI
Dahl_SR_JrHsd9121,908,708 - 121,923,054 (-)NCBI
Lyon_Normotensive9117,757,364 - 117,771,705 (-)NCBI
Lyon_Hypertensive9117,885,333 - 117,899,666 (-)NCBI
F344_StmMcwi9119,862,815 - 119,877,148 (-)NCBI
Rnor_6.09119,307,168 - 119,321,500 (-)NCBI
Rnor_5.09118,761,452 - 118,775,834 (-)NCBI
RGSC_v3.49110,171,418 - 110,186,248 (-)RGD
Celera9108,004,122 - 108,018,394 (-)RGD
Sequence:
RefSeq Acc Id: XM_039084137   ⟹   XP_038940065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89118,320,581 - 118,334,486 (-)NCBI
mRatBN7.29110,873,872 - 110,887,861 (-)NCBI
RefSeq Acc Id: NP_059039   ⟸   NM_017343
- UniProtKB: Q6P9V4 (UniProtKB/Swiss-Prot),   P18666 (UniProtKB/Swiss-Prot),   A0A0G2JSW0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045992   ⟸   ENSRNOT00000048125
RefSeq Acc Id: XP_038940065   ⟸   XM_039084137
- Peptide Label: isoform X1
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18666-F1-model_v2 AlphaFold P18666 1-172 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696910
Promoter ID:EPDNEW_R7435
Type:initiation region
Name:Myl12b_1
Description:myosin light chain 12B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09119,321,483 - 119,321,543EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628855 AgrOrtholog
BioCyc Gene G2FUF-26345 BioCyc
Ensembl Genes ENSRNOG00000015733 Ensembl
  ENSRNOG00000091388 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000048125 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6889406 IMAGE-MGC_LOAD
  IMAGE:7378266 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_DJBP UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Myosin_RLC UniProtKB/Swiss-Prot
KEGG Report rno:50685 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114341 IMAGE-MGC_LOAD
  MGC:72883 IMAGE-MGC_LOAD
NCBI Gene 50685 ENTREZGENE
PANTHER MYOSIN REGULATORY LIGHT CHAIN 2 UniProtKB/Swiss-Prot
Pfam EF-hand_11 UniProtKB/Swiss-Prot
  EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Myl12b PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015733 RatGTEx
  ENSRNOG00000091388 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A0G2JSW0 ENTREZGENE, UniProtKB/TrEMBL
  ML12B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P9V4 ENTREZGENE
UniProt Secondary Q6P9V4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Myl12b  myosin light chain 12B  Myl12b  myosin, light chain 12B, regulatory  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-07 Myl12b  myosin, light chain 12B, regulatory  Mrlc2  myosin regulatory light chain MRLC2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-14 Mrlc2  myosin regulatory light chain MRLC2  Mylc2b  myosin light chain, regulatory B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Mylc2b  myosin light chain, regulatory B  Mrlcb  myosin light chain, regulatory B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Mrlcb  myosin light chain, regulatory B    myosin regulatory light chain  Name updated 1299863 APPROVED
2003-02-27 Mrlcb  myosin regulatory light chain      Symbol and Name status set to provisional 70820 PROVISIONAL