Arhgap39 (Rho GTPase activating protein 39) - Rat Genome Database

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Gene: Arhgap39 (Rho GTPase activating protein 39) Rattus norvegicus
Analyze
Symbol: Arhgap39
Name: Rho GTPase activating protein 39
RGD ID: 1593158
Description: Predicted to be involved in postsynapse organization. Is active in glutamatergic synapse and postsynapse. Orthologous to human ARHGAP39 (Rho GTPase activating protein 39); INTERACTS WITH 2,6-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: KIAA1688; LOC500901; PORF-2; preoptic regulatory factor 2; preoptic regulatory factor-2; rho GTPase-activating protein 39; similar to Protein KIAA1688
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,326,918 - 110,419,500 (-)NCBIGRCr8
mRatBN7.27108,446,280 - 108,538,875 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,446,282 - 108,538,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,188,071 - 110,280,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,411,646 - 112,504,442 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,372,384 - 112,465,862 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,788,716 - 117,880,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,788,716 - 117,880,289 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,776,694 - 117,869,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,776,991 - 114,866,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,811,218 - 114,812,726 (-)NCBI
Celera7104,795,774 - 104,888,020 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
glutamatergic synapse  (IDA,IEA,ISO)
postsynapse  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons. Lim J, etal., Curr Biol. 2014 Mar 31;24(7):786-92. doi: 10.1016/j.cub.2014.02.036. Epub 2014 Mar 20.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2293025   PMID:8889548  


Genomics

Comparative Map Data
Arhgap39
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,326,918 - 110,419,500 (-)NCBIGRCr8
mRatBN7.27108,446,280 - 108,538,875 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,446,282 - 108,538,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,188,071 - 110,280,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,411,646 - 112,504,442 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,372,384 - 112,465,862 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,788,716 - 117,880,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,788,716 - 117,880,289 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,776,694 - 117,869,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,776,991 - 114,866,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,811,218 - 114,812,726 (-)NCBI
Celera7104,795,774 - 104,888,020 (-)NCBICelera
Cytogenetic Map7q34NCBI
ARHGAP39
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,529,179 - 144,700,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,529,179 - 144,685,846 (-)EnsemblGRCh38hg38GRCh38
GRCh378145,754,563 - 145,911,231 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,725,371 - 145,809,699 (-)NCBINCBI36Build 36hg18NCBI36
Celera8141,930,235 - 142,014,662 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,868,048 - 140,952,786 (-)NCBIHuRef
CHM1_18145,792,842 - 145,877,172 (-)NCBICHM1_1
T2T-CHM13v2.08145,699,369 - 145,873,884 (-)NCBIT2T-CHM13v2.0
Arhgap39
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,608,183 - 76,702,366 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,608,185 - 76,702,370 (-)EnsemblGRCm39 Ensembl
GRCm381576,723,985 - 76,818,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,723,985 - 76,818,170 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,554,415 - 76,648,600 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,551,240 - 76,645,406 (-)NCBIMGSCv36mm8
Celera1578,217,595 - 78,313,095 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
Arhgap39
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,153,755 - 3,212,357 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,153,755 - 3,213,298 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP39
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27162,021,348 - 162,171,351 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,550,683 - 137,702,815 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,298,070 - 141,449,560 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,285,624 - 144,361,501 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,285,624 - 144,361,501 (-)Ensemblpanpan1.1panPan2
ARHGAP39
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,945,480 - 38,002,738 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,947,888 - 37,993,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,908,650 - 37,997,583 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,421,639 - 38,510,885 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11338,113,586 - 38,202,462 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,221,985 - 38,311,017 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,698,476 - 38,787,684 (-)NCBIUU_Cfam_GSD_1.0
Arhgap39
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303267,656 - 318,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,703,125 - 7,744,161 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,703,107 - 7,744,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP39
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4206,188 - 273,644 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14206,135 - 274,998 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24335,864 - 366,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP39
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,743,479 - 138,886,662 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,743,403 - 138,886,602 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666039963,786 - 1,111,432 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap39
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,236,122 - 12,334,404 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,236,219 - 12,334,461 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgap39
228 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:172
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000052227
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat

Markers in Region
D7Arb11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,446,301 - 108,446,618 (+)MAPPERmRatBN7.2
Rnor_6.07117,788,736 - 117,789,052NCBIRnor6.0
Rnor_5.07117,776,714 - 117,777,030UniSTSRnor5.0
RGSC_v3.47114,777,011 - 114,777,327UniSTSRGSC3.4
RGSC_v3.17114,811,240 - 114,811,557RGD
Celera7104,795,794 - 104,796,110UniSTS
Cytogenetic Map7q34UniSTS
RH128528  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,446,560 - 108,446,743 (+)MAPPERmRatBN7.2
Rnor_6.07117,788,995 - 117,789,177NCBIRnor6.0
Rnor_5.07117,776,973 - 117,777,155UniSTSRnor5.0
RGSC_v3.47114,777,270 - 114,777,452UniSTSRGSC3.4
Celera7104,796,053 - 104,796,235UniSTS
RH 3.4 Map7793.2UniSTS
Cytogenetic Map7q34UniSTS
D15Wsu169e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,446,283 - 108,446,515 (+)MAPPERmRatBN7.2
Rnor_6.07117,788,718 - 117,788,949NCBIRnor6.0
Rnor_5.07117,776,696 - 117,776,927UniSTSRnor5.0
RGSC_v3.47114,776,993 - 114,777,224UniSTSRGSC3.4
Celera7104,795,776 - 104,796,007UniSTS
Cytogenetic Map7q34UniSTS
RH143245  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,451,370 - 108,451,526 (+)MAPPERmRatBN7.2
Rnor_6.07117,793,805 - 117,793,960NCBIRnor6.0
Rnor_5.07117,781,783 - 117,781,938UniSTSRnor5.0
RGSC_v3.47114,782,080 - 114,782,235UniSTSRGSC3.4
Celera7104,800,863 - 104,801,018UniSTS
RH 3.4 Map7790.6UniSTS
Cytogenetic Map7q34UniSTS
RH143777  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,465,688 - 108,465,825 (+)MAPPERmRatBN7.2
Rnor_6.07117,808,122 - 117,808,258NCBIRnor6.0
Rnor_5.07117,796,100 - 117,796,236UniSTSRnor5.0
RGSC_v3.47114,796,397 - 114,796,533UniSTSRGSC3.4
Celera7104,815,180 - 104,815,316UniSTS
RH 3.4 Map7793.5UniSTS
Cytogenetic Map7q34UniSTS
RH144294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,455,397 - 108,455,553 (+)MAPPERmRatBN7.2
Rnor_6.07117,797,831 - 117,797,986NCBIRnor6.0
Rnor_5.07117,785,809 - 117,785,964UniSTSRnor5.0
RGSC_v3.47114,786,106 - 114,786,261UniSTSRGSC3.4
Celera7104,804,889 - 104,805,044UniSTS
RH 3.4 Map7793.5UniSTS
Cytogenetic Map7q34UniSTS
AI843066  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,446,504 - 108,446,614 (+)MAPPERmRatBN7.2
Rnor_6.07117,788,939 - 117,789,048NCBIRnor6.0
Rnor_5.07117,776,917 - 117,777,026UniSTSRnor5.0
RGSC_v3.47114,777,214 - 114,777,323UniSTSRGSC3.4
Celera7104,795,997 - 104,796,106UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 4 2 2 9 2 74 16 31
Low 2 39 55 39 10 39 8 11 19 10 11 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_173122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE115584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ194144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB578147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000052227   ⟹   ENSRNOP00000051450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,446,282 - 108,538,831 (-)Ensembl
Rnor_6.0 Ensembl7117,788,716 - 117,880,289 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104965   ⟹   ENSRNOP00000076721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,446,282 - 108,538,831 (-)Ensembl
RefSeq Acc Id: NM_173122   ⟹   NP_775145
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,326,918 - 110,419,460 (-)NCBI
mRatBN7.27108,446,282 - 108,538,831 (-)NCBI
Rnor_6.07117,788,716 - 117,880,289 (-)NCBI
Rnor_5.07117,776,694 - 117,869,381 (-)NCBI
RGSC_v3.47114,776,991 - 114,866,861 (-)RGD
Celera7104,795,774 - 104,888,020 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241866   ⟹   XP_006241928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,326,918 - 110,419,499 (-)NCBI
mRatBN7.27108,446,280 - 108,538,875 (-)NCBI
Rnor_6.07117,788,718 - 117,880,328 (-)NCBI
Rnor_5.07117,776,694 - 117,869,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241867   ⟹   XP_006241929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,326,918 - 110,419,499 (-)NCBI
mRatBN7.27108,447,333 - 108,538,874 (-)NCBI
Rnor_6.07117,788,718 - 117,880,327 (-)NCBI
Rnor_5.07117,776,694 - 117,869,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595054   ⟹   XP_017450543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,326,918 - 110,419,235 (-)NCBI
mRatBN7.27108,447,333 - 108,538,586 (-)NCBI
Rnor_6.07117,788,718 - 117,880,017 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595056   ⟹   XP_017450545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,330,596 - 110,419,500 (-)NCBI
mRatBN7.27108,449,962 - 108,538,875 (-)NCBI
Rnor_6.07117,795,300 - 117,880,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079761   ⟹   XP_038935689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,326,918 - 110,408,388 (-)NCBI
mRatBN7.27108,447,333 - 108,525,438 (-)NCBI
RefSeq Acc Id: XM_039079762   ⟹   XP_038935690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,329,875 - 110,419,500 (-)NCBI
mRatBN7.27108,449,241 - 108,538,875 (-)NCBI
RefSeq Acc Id: XM_063264134   ⟹   XP_063120204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,328,172 - 110,419,499 (-)NCBI
RefSeq Acc Id: XM_063264135   ⟹   XP_063120205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,329,875 - 110,419,500 (-)NCBI
RefSeq Acc Id: XR_005486708
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,330,615 - 110,419,500 (-)NCBI
mRatBN7.27108,449,979 - 108,538,875 (-)NCBI
RefSeq Acc Id: XR_005486709
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,329,972 - 110,419,500 (-)NCBI
mRatBN7.27108,449,346 - 108,538,875 (-)NCBI
RefSeq Acc Id: NP_775145   ⟸   NM_173122
- UniProtKB: F1LR18 (UniProtKB/TrEMBL),   A6HSD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241928   ⟸   XM_006241866
- Peptide Label: isoform X2
- UniProtKB: A6HSD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241929   ⟸   XM_006241867
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y0P2 (UniProtKB/TrEMBL),   A6HSD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450543   ⟸   XM_017595054
- Peptide Label: isoform X1
- UniProtKB: F1LR18 (UniProtKB/TrEMBL),   A6HSD4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450545   ⟸   XM_017595056
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000051450   ⟸   ENSRNOT00000052227
RefSeq Acc Id: XP_038935689   ⟸   XM_039079761
- Peptide Label: isoform X1
- UniProtKB: F1LR18 (UniProtKB/TrEMBL),   A6HSD4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935690   ⟸   XM_039079762
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000076721   ⟸   ENSRNOT00000104965
RefSeq Acc Id: XP_063120204   ⟸   XM_063264134
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063120205   ⟸   XM_063264135
- Peptide Label: isoform X7
Protein Domains
MyTH4   Rho-GAP   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18890-F1-model_v2 AlphaFold P18890 1-101 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695442
Promoter ID:EPDNEW_R5965
Type:multiple initiation site
Name:Arhgap39_1
Description:Rho GTPase activating protein 39
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07117,880,277 - 117,880,337EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593158 AgrOrtholog
BioCyc Gene G2FUF-32903 BioCyc
Ensembl Genes ENSRNOG00000016566 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052227 ENTREZGENE
  ENSRNOT00000052227.4 UniProtKB/TrEMBL
  ENSRNOT00000104965.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
InterPro MyTH4_dom UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  WW_Rsp5_WWP UniProtKB/TrEMBL
KEGG Report rno:500901 UniProtKB/TrEMBL
NCBI Gene 500901 ENTREZGENE
PANTHER FI04035P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 39 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MyTH4 UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arhgap39 PhenoGen
PROSITE MYTH4 UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016566 RatGTEx
SMART MyTH4 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
UniProt A0A8I5Y0P2 ENTREZGENE, UniProtKB/TrEMBL
  A6HSD4 ENTREZGENE, UniProtKB/TrEMBL
  F1LR18 ENTREZGENE, UniProtKB/TrEMBL
  P18890 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Arhgap39  Rho GTPase activating protein 39  Porf-2  preoptic regulatory factor-2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-01-22 Porf-2  preoptic regulatory factor-2  LOC500901  similar to Protein KIAA1688  Symbol and Name updated 1299863 APPROVED
2009-01-22 LOC500901  similar to Protein KIAA1688  PORF-2  preoptic regulatory factor-2  Data merged from RGD:735095 737654 APPROVED
2006-11-20 LOC500901  similar to Protein KIAA1688      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-10-12 PORF-2        Symbol and Name status set to provisional 70820 PROVISIONAL