RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: hypoglycemia
Accession: DOID:9993
browse the term
Definition: A glucose metabolism disease that is characterized by abnormally low levels of blood glucose. (DO)
Synonyms: exact_synonym: Fasting Hypoglycemia; Postabsorptive Hypoglycemia; Postprandial Hypoglycemia; Reactive Hypoglycemia; hypoglycaemia
primary_id: MESH:D007003
xref: ICD10CM:E16.2 ; ICD9CM:251.2 ; NCI:C3126
G
Abcc8
ATP binding cassette subfamily C member 8
IMP ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar RGD
PMID:10204114 PMID:10685980 PMID:16380471 PMID:16416420 PMID:16613899 PMID:16885549 PMID:17539904 PMID:18025408 PMID:18596924 PMID:18981553 PMID:20849526 PMID:21989597 PMID:22210575 PMID:23275527 PMID:23345197 PMID:25741868 PMID:26467025 PMID:27538677 PMID:28492532 PMID:30297969 PMID:30447144 PMID:31604004 PMID:32027066 PMID:32041611 PMID:32640185 PMID:32792356 PMID:33565752 PMID:34171966 PMID:34426522 PMID:34462253 PMID:36208030 PMID:18776135 More...
RGD:2301896
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Agtr2
angiotensin II receptor, type 2
ISO
associated with Diabetes Mellitus, Insulin-Dependent;DNA:polymorphism: :1675G>A (human)
RGD
PMID:18328310
RGD:2313551
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
G
Ahr
aryl hydrocarbon receptor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:34848246
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Akt2
AKT serine/threonine kinase 2
ISO
RGD
PMID:21979934
RGD:7248543
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
G
Cacna1c
calcium voltage-gated channel subunit alpha1 C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15454078
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
G
Creb1
cAMP responsive element binding protein 1
ISO
RGD
PMID:11557984
RGD:734816
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Crh
corticotropin releasing hormone
IDA
RGD
PMID:12606499
RGD:704397
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Epo
erythropoietin
ISO
associated with Diabetes Mellitus, Insulin-Dependent;protein:increased expression:plasma
RGD
PMID:19211168
RGD:2313835
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar
PMID:2172641 PMID:7573034 PMID:7623438 PMID:7744838 PMID:7814621 PMID:8182131 PMID:8211187 PMID:8734807 PMID:9332655 PMID:10612834 PMID:10834516 PMID:10874313 PMID:11310582 PMID:11739393 PMID:12093795 PMID:12373566 PMID:12713862 PMID:15316959 PMID:18008183 PMID:18449899 PMID:20301489 PMID:21599942 PMID:23312056 PMID:24033266 PMID:24082139 PMID:24385852 PMID:25308557 PMID:25333069 PMID:25741868 PMID:28397058 PMID:28492532 PMID:29750741 PMID:32313153 PMID:33224545 PMID:33763395 PMID:34093448 More...
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
G
Gck
glucokinase
ISO
hyperinsulinemic hypoglycemia,OMIM:602485;DNA:point mutation:exon:V455M
RGD
PMID:9435328
RGD:1601294
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Glud1
glutamate dehydrogenase 1
ISO
familial hyperinsulinemic hypoglycemia-6,OMIM:606762;DNA:point mutation:exon:E296A
RGD
PMID:10636977
RGD:1601353
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gpx3
glutathione peroxidase 3
ISO
mRNA:increased expression:retina
RGD
PMID:21738719
RGD:401827130
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
IEP
mRNA, protein:increased expression:cerebellum (rat)
RGD
PMID:20056114
RGD:4107025
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Gsr
glutathione-disulfide reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20620209
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Hnf1a
HNF1 homeobox A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15787664
NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
G
Hnf4a
hepatocyte nuclear factor 4, alpha
ISO
associated with Hyperinsulinemia;DNA:frameshift mutation, nonsense mutation, splice-site mutation
RGD
PMID:18268044 PMID:17407387
RGD:2301837 , RGD:12904698
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Igf2
insulin-like growth factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:3185662
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:1884014
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Inppl1
inositol polyphosphate phosphatase-like 1
ISO
RGD
PMID:11343120
RGD:737755
NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
G
Ins1
insulin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:222008 PMID:3084764 PMID:6797439 PMID:18545258
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Ins2
insulin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:48835 PMID:1324617 PMID:1646414 PMID:1890151 PMID:2554359 PMID:20620209 PMID:22940631 More...
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar
PMID:18596924 PMID:20032456 PMID:23700433 PMID:27908292 PMID:31464105
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Myom1
myomesin 1
ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
G
Nsd2
nuclear receptor binding SET domain protein 2
ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar
PMID:25741868
NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
ISO
RGD
PMID:9988280
RGD:737788
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
G
Pnmt
phenylethanolamine-N-methyltransferase
IEP
associated with Diabetes Mellitus, Experimental; mRNA:decreased expression:adrenal gland (rat)
RGD
PMID:15494609
RGD:5130725
NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
G
Ppara
peroxisome proliferator activated receptor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16777972
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:insertion/deletion:3' UTR (human)
RGD
PMID:9814479
RGD:1601469
NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638
G
Prl
prolactin
ISO
associated with Hypertension
RGD
PMID:16617309
RGD:1642557
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
G
Scn9a
sodium voltage-gated channel alpha subunit 9
ISO
ClinVar Annotator: match by term: Hypoglycemia
ClinVar
PMID:19763161 PMID:22604722 PMID:23129781 PMID:25250524 PMID:25741868 PMID:26467025 PMID:27504264 PMID:28492532 PMID:29176367 PMID:30642272 PMID:33216760 More...
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
G
Serpina1
serpin family A member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17659342
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
G
Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20620209
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Th
tyrosine hydroxylase
IEP
associated with Diabetes Mellitus, Experimental; protein:increased expression:adrenal gland (rat)
RGD
PMID:16396986
RGD:5130724
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8774068
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Ucp3
uncoupling protein 3
ISO
RGD
PMID:10935638
RGD:737762
NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
G
Piezo1
piezo-type mechanosensitive ion channel component 1
ISO
ClinVar Annotator: match by term: ACTH deficiency
ClinVar
PMID:25741868
NCBI chr19:50,544,580...50,606,812
Ensembl chr19:50,544,582...50,606,501
G
Rpe65
retinoid isomerohydrolase RPE65
ISO
ClinVar Annotator: match by term: ACTH deficiency
ClinVar
PMID:9326941 PMID:9501220 PMID:9843205 PMID:18632300 PMID:25741868 PMID:28492532 PMID:30576320 PMID:31273949 PMID:31630094 More...
NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
G
Tbx19
T-box transcription factor 19
ISO ISS
OMIM:201400 ClinVar Annotator: match by term: ACTH deficiency CTD Direct Evidence: marker/mechanism
OMIM MouseDO ClinVar CTD
PMID:2830787 PMID:9536098 PMID:11290323 PMID:12651888 PMID:15476446 PMID:15613420 PMID:16390921 PMID:17576681 PMID:17652218 PMID:22170728 PMID:25326635 PMID:25741868 PMID:28492532 PMID:33423260 More...
NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163
G
Cpt1a
carnitine palmitoyltransferase 1A
ISO ISS
ClinVar Annotator: match by term: Carnitine palmitoyl transferase 1A deficiency OMIM:255120 CTD Direct Evidence: marker/mechanism
OMIM ClinVar MouseDO CTD
PMID:9048718 PMID:9536098 PMID:9691089 PMID:11350182 PMID:11350183 PMID:11441142 PMID:12111367 PMID:12189492 PMID:12351641 PMID:14517221 PMID:15110323 PMID:16169268 PMID:16199547 PMID:16958601 PMID:17576681 PMID:19181627 PMID:19217814 PMID:19345525 PMID:20301700 PMID:20696606 PMID:21253826 PMID:21763168 PMID:21962599 PMID:23090344 PMID:23430491 PMID:23430868 PMID:23430932 PMID:23700290 PMID:24033266 PMID:24847810 PMID:25449608 PMID:25640679 PMID:25741868 PMID:26010953 PMID:26820065 PMID:27066452 PMID:27341449 PMID:28125087 PMID:28468868 PMID:28492532 PMID:29519241 PMID:30101502 PMID:31319225 PMID:32088118 PMID:32561900 PMID:32781271 PMID:33845545 PMID:34131458 PMID:34869124 PMID:35360862 More...
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpt2
carnitine palmitoyltransferase 2
susceptibility
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: CPT2 DEFICIENCY, INFANTILE | ClinVar Annotator: match by term: Carnitine palmitoyltransferase II deficiency, infantile
CTD OMIM ClinVar
PMID:736528 PMID:835844 PMID:1086878 PMID:1528846 PMID:1999498 PMID:2647738 PMID:2762996 PMID:7711730 PMID:8358442 PMID:8651281 PMID:8682496 PMID:8786066 PMID:9309694 PMID:9536098 PMID:9562964 PMID:9600456 PMID:9758712 PMID:10090476 PMID:10398215 PMID:10734268 PMID:10862092 PMID:10868782 PMID:10873395 PMID:11477613 PMID:11855939 PMID:11994355 PMID:12362414 PMID:12410208 PMID:12673791 PMID:12707442 PMID:14605500 PMID:14615409 PMID:15363638 PMID:15622536 PMID:15642848 PMID:15754283 PMID:15776096 PMID:15811315 PMID:16168441 PMID:16199547 PMID:16615913 PMID:16781677 PMID:16996287 PMID:17372854 PMID:17576681 PMID:17651973 PMID:17709715 PMID:17936304 PMID:18306170 PMID:18363739 PMID:18550408 PMID:18577113 PMID:18645163 PMID:18925671 PMID:19239046 PMID:19762733 PMID:20301431 PMID:20543534 PMID:20661589 PMID:20810031 PMID:20830526 PMID:20934285 PMID:20952238 PMID:21227726 PMID:21697855 PMID:21709843 PMID:21913903 PMID:22494076 PMID:22652984 PMID:22841441 PMID:22854105 PMID:22899091 PMID:22975760 PMID:23184072 PMID:23322164 PMID:23700290 PMID:23757202 PMID:23911907 PMID:24033266 PMID:24398345 PMID:24503134 PMID:24517888 PMID:24563797 PMID:24602495 PMID:25326635 PMID:25604974 PMID:25741868 PMID:25827434 PMID:25919294 PMID:26467025 PMID:26477380 PMID:26537576 PMID:26636822 PMID:27067077 PMID:27123472 PMID:27578510 PMID:27629963 PMID:27974123 PMID:28074886 PMID:28492532 PMID:28516040 PMID:28529889 PMID:28600779 PMID:28779239 PMID:28801073 PMID:28871440 PMID:29478820 PMID:29552494 PMID:29744303 PMID:30094188 PMID:30149802 PMID:30293990 PMID:30455135 PMID:30609409 PMID:30957255 PMID:31372341 PMID:31770251 PMID:32295037 PMID:32489884 PMID:32528171 PMID:33123633 PMID:34063237 More...
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Abcc8
ATP binding cassette subfamily C member 8
ISO
ClinVar Annotator: match by term: Congenital hyperinsulinism | ClinVar Annotator: match by term: Familial hyperinsulinism | ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL DNA:mutations:exon:multiple DNA:missense mutations, nonsense mutations, splice-site mutations:CDS:multiple DNA:missense mutations:exon:p.G1485E (c.4454G>A), p.D1506E (c.4518C>A), p.M1544K (c.4541T>A) (human) DNA:mutations:exon, intron:multiple DNA:deletion: :p.S1387del (human) CTD Direct Evidence: marker/mechanism
ClinVar CTD RGD
PMID:3202066 PMID:7716548 PMID:8751851 PMID:8923011 PMID:9041101 PMID:9536098 PMID:9618169 PMID:9648840 PMID:9867219 PMID:10194514 PMID:10334322 PMID:10338089 PMID:10447255 PMID:10487673 PMID:10615958 PMID:10685980 PMID:10720932 PMID:10923633 PMID:11226335 PMID:11272143 PMID:11318841 PMID:11692183 PMID:11872696 PMID:11999683 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:12784138 PMID:12941782 PMID:14692646 PMID:14715863 PMID:14764815 PMID:15111507 PMID:15356046 PMID:15466080 PMID:15562009 PMID:15579781 PMID:15579791 PMID:15797964 PMID:15807877 PMID:15855351 PMID:16186397 PMID:16199547 PMID:16357843 PMID:16416420 PMID:16429405 PMID:16455067 PMID:16613899 PMID:16860127 PMID:16882742 PMID:16885549 PMID:16969006 PMID:17236890 PMID:17257281 PMID:17378627 PMID:17384337 PMID:17446535 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17466004 PMID:17575084 PMID:17576681 PMID:17668386 PMID:17823772 PMID:17919176 PMID:18025408 PMID:18339976 PMID:18414213 PMID:18436707 PMID:18493152 PMID:18758683 PMID:18767144 PMID:18796520 PMID:18981553 PMID:18988933 PMID:19151370 PMID:19214942 PMID:19233137 PMID:19475716 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20215776 PMID:20301620 PMID:20424228 PMID:20427569 PMID:20432820 PMID:20672374 PMID:20685672 PMID:20799350 PMID:20943781 PMID:21199866 PMID:21321069 PMID:21378087 PMID:21716120 PMID:21835061 PMID:21851374 PMID:21968111 PMID:21989597 PMID:21992908 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22264780 PMID:22311976 PMID:22591706 PMID:22704848 PMID:22749773 PMID:22796691 PMID:22802590 PMID:22855730 PMID:23067144 PMID:23261959 PMID:23275527 PMID:23345197 PMID:23506826 PMID:23652837 PMID:23744072 PMID:23771172 PMID:24145932 PMID:24401662 PMID:24434300 PMID:24616771 PMID:24622368 PMID:24645945 PMID:24686051 PMID:24937539 PMID:25008049 PMID:25117148 PMID:25201519 PMID:25306193 PMID:25323548 PMID:25518065 PMID:25584046 PMID:25639667 PMID:25741868 PMID:25781672 PMID:25931474 PMID:25972930 PMID:26180531 PMID:26431509 PMID:26467025 PMID:26545620 PMID:26740944 PMID:27175728 PMID:27188453 PMID:27538677 PMID:27573238 PMID:27682711 PMID:27754802 PMID:27810688 PMID:27908292 PMID:28270372 PMID:28439221 PMID:28442472 PMID:28492532 PMID:28667717 PMID:29082728 PMID:29893194 PMID:30114684 PMID:30186238 PMID:30352420 PMID:30354297 PMID:30386300 PMID:30395892 PMID:30462810 PMID:30487145 PMID:31218401 PMID:31291970 PMID:31464105 PMID:31479591 PMID:31525223 PMID:31589614 PMID:31821855 PMID:32027066 PMID:32170320 PMID:32267248 PMID:32670376 PMID:32792356 PMID:32893419 PMID:33046911 PMID:33240318 PMID:33410562 PMID:33477506 PMID:33587123 PMID:34253504 PMID:34566892 PMID:34764980 PMID:34927408 PMID:34992182 PMID:36339418 PMID:36699461 PMID:7716548 PMID:23506826 PMID:23652837 PMID:20573158 PMID:16429405 PMID:24401662 PMID:21422196 PMID:18596924 More...
RGD:704365 , RGD:12790723 , RGD:11069847 , RGD:12790596 , RGD:11067821 , RGD:12790587 , RGD:11070657 , RGD:12743628
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Gck
glucokinase
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Familial hyperinsulinism
CTD ClinVar
PMID:15277402 PMID:19053014 PMID:19336674 PMID:21831042 PMID:23890519 PMID:25733449 PMID:27802864 PMID:31094068 PMID:34532767 PMID:34680961 More...
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Glud1
glutamate dehydrogenase 1
ISO
RGD
PMID:9571255
RGD:1302513
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Hadh
hydroxyacyl-CoA dehydrogenase
ISO
DNA:deletion:cds (human)
RGD
PMID:14693719
RGD:2306664
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
G
Hnf4a
hepatocyte nuclear factor 4, alpha
ISO
DNA:mutations: : ClinVar Annotator: match by term: Congenital hyperinsulinism | ClinVar Annotator: match by term: Familial hyperinsulinism
ClinVar RGD
PMID:10227563 PMID:10447526 PMID:10983627 PMID:12669197 PMID:15281001 PMID:15793260 PMID:15928245 PMID:16883527 PMID:16946562 PMID:17563455 PMID:18268044 PMID:18414213 PMID:20164212 PMID:21105491 PMID:22140441 PMID:22232426 PMID:23227446 PMID:23247789 PMID:24033266 PMID:24097065 PMID:24476040 PMID:25041077 PMID:25631608 PMID:25741868 PMID:25905084 PMID:26059258 PMID:26467025 PMID:26512799 PMID:26740944 PMID:26981542 PMID:27080136 PMID:27420379 PMID:27884173 PMID:28492532 PMID:29207974 PMID:29355436 PMID:29792621 PMID:30191603 PMID:31264968 PMID:31595705 PMID:32583173 PMID:33846082 PMID:34373539 PMID:34805411 PMID:35052457 PMID:35118593 PMID:35256061 PMID:20164212 More...
RGD:12904701
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Familial hyperinsulinism | ClinVar Annotator: match by term: HYPERINSULINISM, NEONATAL DNA:SNPs:exon:c.151G>T, c.1017G>T (human) DNA:missense mutations, frameshift mutations:CDS:multiple DNA:deletion, frameshift mutation, missense mutations:exon:multiple DNA:deletion, insertion:exon DNA:missense mutation:exon:p.R34H (c.101G>A) (human)
CTD ClinVar RGD
PMID:9867219 PMID:10559219 PMID:11318841 PMID:11692183 PMID:11872696 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:15111507 PMID:15579781 PMID:15579791 PMID:15580558 PMID:15718250 PMID:15797964 PMID:15855351 PMID:15886397 PMID:16357843 PMID:16455067 PMID:17257281 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17823772 PMID:18414213 PMID:18758683 PMID:19214942 PMID:19233137 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20301620 PMID:20424228 PMID:20980454 PMID:21119644 PMID:21544516 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22264780 PMID:22591706 PMID:22701567 PMID:22704848 PMID:23275527 PMID:24018988 PMID:24383515 PMID:24401662 PMID:25741868 PMID:26448950 PMID:26467025 PMID:27908292 PMID:28123437 PMID:28492532 PMID:28938416 PMID:29893194 PMID:30377186 PMID:32935446 PMID:36208030 PMID:23506826 PMID:23652837 PMID:24401662 PMID:17316607 PMID:24421282 More...
RGD:12790723 , RGD:11069847 , RGD:12790587 , RGD:12743643 , RGD:12743624
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Kcnt2
potassium sodium-activated channel subfamily T member 2
ISO
ClinVar Annotator: match by term: KCNT2-related condition
ClinVar
PMID:25741868 PMID:29069600
NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987
G
Tbc1d4
TBC1 domain family, member 4
ISO
RGD
PMID:19470471
RGD:7248544
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
G
Abcc8
ATP binding cassette subfamily C member 8
ISO
ClinVar Annotator: match by term: Congenital isolated hyperinsulinism | ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
OMIM ClinVar
PMID:1021286 PMID:2198959 PMID:3202066 PMID:7716548 PMID:8650576 PMID:8751851 PMID:8923011 PMID:9041101 PMID:9075812 PMID:9382893 PMID:9519757 PMID:9536098 PMID:9568693 PMID:9618169 PMID:9642650 PMID:9648840 PMID:9769320 PMID:10194514 PMID:10202168 PMID:10204114 PMID:10334322 PMID:10338089 PMID:10400694 PMID:10426386 PMID:10447255 PMID:10487673 PMID:10615958 PMID:10685979 PMID:10685980 PMID:10720932 PMID:10828824 PMID:10857971 PMID:10923633 PMID:10993895 PMID:11018078 PMID:11226335 PMID:11272143 PMID:11395395 PMID:11457841 PMID:11697420 PMID:11867634 PMID:11999683 PMID:12166651 PMID:12169627 PMID:12199344 PMID:12364426 PMID:12559865 PMID:12627323 PMID:12784138 PMID:12941782 PMID:14593442 PMID:14692646 PMID:14715863 PMID:14764815 PMID:15111507 PMID:15356046 PMID:15371948 PMID:15466080 PMID:15561897 PMID:15562009 PMID:15579781 PMID:15580558 PMID:15718250 PMID:15807877 PMID:15842514 PMID:16186397 PMID:16199547 PMID:16357843 PMID:16367916 PMID:16380471 PMID:16416420 PMID:16429405 PMID:16442101 PMID:16613899 PMID:16860127 PMID:16882742 PMID:16885549 PMID:16969006 PMID:17236890 PMID:17378627 PMID:17384337 PMID:17389331 PMID:17446535 PMID:17466004 PMID:17539904 PMID:17575084 PMID:17576681 PMID:17597441 PMID:17668386 PMID:17823772 PMID:17919176 PMID:17957187 PMID:17990484 PMID:18025408 PMID:18025464 PMID:18073294 PMID:18339976 PMID:18346985 PMID:18390792 PMID:18414213 PMID:18436707 PMID:18493152 PMID:18596924 PMID:18599530 PMID:18758683 PMID:18767144 PMID:18796520 PMID:18981553 PMID:18988933 PMID:19151370 PMID:19475716 PMID:19766903 PMID:19933268 PMID:20042013 PMID:20215776 PMID:20427569 PMID:20432820 PMID:20573158 PMID:20672374 PMID:20685672 PMID:20799350 PMID:20849526 PMID:20922570 PMID:20943779 PMID:20943781 PMID:21109997 PMID:21142918 PMID:21199866 PMID:21214702 PMID:21321069 PMID:21378087 PMID:21411514 PMID:21422196 PMID:21536946 PMID:21544516 PMID:21617188 PMID:21674179 PMID:21716120 PMID:21814221 PMID:21835061 PMID:21851374 PMID:21968111 PMID:21978130 PMID:21989597 PMID:21992908 PMID:22151254 PMID:22210575 PMID:22308858 PMID:22311976 PMID:22451668 PMID:22533711 PMID:22562119 PMID:22662265 PMID:22704848 PMID:22749773 PMID:22796691 PMID:22802363 PMID:22802590 PMID:22855730 PMID:22876564 PMID:22902787 PMID:23067144 PMID:23226049 PMID:23261959 PMID:23266803 PMID:23273570 PMID:23275527 PMID:23301914 PMID:23345197 PMID:23506826 PMID:23652837 PMID:23744072 PMID:23771172 PMID:23771920 PMID:23798684 PMID:23903354 PMID:24033266 PMID:24044690 PMID:24072082 PMID:24080777 PMID:24145932 PMID:24332968 PMID:24401662 PMID:24411943 PMID:24434300 PMID:24616771 PMID:24622368 PMID:24645945 PMID:24686051 PMID:24750227 PMID:24768178 PMID:24814349 PMID:24937539 PMID:24959012 PMID:25008049 PMID:25117148 PMID:25201519 PMID:25306193 PMID:25323548 PMID:25518065 PMID:25525159 PMID:25555642 PMID:25584046 PMID:25639667 PMID:25720052 PMID:25741868 PMID:25765446 PMID:25781672 PMID:25871929 PMID:25931474 PMID:25955821 PMID:25972930 PMID:26162674 PMID:26180531 PMID:26208381 PMID:26246406 PMID:26268944 PMID:26316440 PMID:26379717 PMID:26431509 PMID:26448950 PMID:26467025 PMID:26545620 PMID:26545876 PMID:26594346 PMID:26740944 PMID:26758964 PMID:26839896 PMID:27175728 PMID:27188453 PMID:27313609 PMID:27334808 PMID:27538677 PMID:27573238 PMID:27677908 PMID:27681997 PMID:27682711 PMID:27691052 PMID:27754802 PMID:27810688 PMID:27889714 PMID:27908292 PMID:27913849 PMID:28018462 PMID:28095440 PMID:28270372 PMID:28346775 PMID:28439221 PMID:28442472 PMID:28492532 PMID:28529015 PMID:28587604 PMID:28663158 PMID:28667717 PMID:28757749 PMID:28791793 PMID:29082728 PMID:29127764 PMID:29207974 PMID:29216354 PMID:29644095 PMID:29675256 PMID:29751826 PMID:30004997 PMID:30098243 PMID:30114684 PMID:30186238 PMID:30191644 PMID:30276209 PMID:30297969 PMID:30352420 PMID:30354297 PMID:30386300 PMID:30395892 PMID:30447144 PMID:30462810 PMID:30487145 PMID:30515958 PMID:30977832 PMID:31002010 PMID:31110826 PMID:31208162 PMID:31218401 PMID:31291970 PMID:31464105 PMID:31479591 PMID:31525223 PMID:31589614 PMID:31595705 PMID:31604004 PMID:31727138 PMID:31821855 PMID:31997554 PMID:32027066 PMID:32041611 PMID:32170320 PMID:32202736 PMID:32267248 PMID:32376986 PMID:32640185 PMID:32670376 PMID:32763092 PMID:32792356 PMID:32893419 PMID:32928245 PMID:32934261 PMID:33046911 PMID:33240318 PMID:33300273 PMID:33400071 PMID:33410562 PMID:33477506 PMID:33502730 PMID:33587123 PMID:33728157 PMID:34015902 PMID:34171966 PMID:34194474 PMID:34253504 PMID:34304300 PMID:34309670 PMID:34426522 PMID:34462253 PMID:34566892 PMID:34631896 PMID:34764980 PMID:34777243 PMID:34927408 PMID:34992182 PMID:35402560 PMID:36339418 PMID:36407475 PMID:36626423 PMID:36699461 More...
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Andpro
androgen regulated protein
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966
G
Banf2
BANF family member 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,387,107...131,442,837
Ensembl chr 3:131,388,130...131,442,832
G
Bfsp1
beaded filament structural protein 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337
G
Cd93
CD93 molecule
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378
G
Cfap61
cilia and flagella associated protein 61
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,354,400...133,633,310
Ensembl chr 3:133,354,197...133,633,320
G
Crnkl1
crooked neck pre-mRNA splicing factor 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302 Ensembl chr 6:133,337,039...133,354,302
G
Cst11
cystatin 11
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,211,414...136,214,138
Ensembl chr 3:136,211,414...136,214,138
G
Cst3
cystatin C
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
G
Cst5
cystatin D
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754
G
Cst8
cystatin 8
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,244,586...136,255,412
Ensembl chr 3:136,244,636...136,251,273
G
Cst9l
cystatin 9-like
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,288,093...136,290,906
Ensembl chr 3:136,288,093...136,290,906
G
Cstl1
cystatin-like 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,199,914...136,204,912
Ensembl chr 3:136,199,914...136,204,912
G
Dstn
destrin, actin depolymerizing factor
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
G
Dtd1
D-aminoacyl-tRNA deacylase 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659
G
Dzank1
double zinc ribbon and ankyrin repeat domains 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,855,890...131,908,217
Ensembl chr 3:131,852,552...131,908,156
G
Foxa2
forkhead box A2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
G
Gzf1
GDNF-inducible zinc finger protein 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,119,004...136,131,223
Ensembl chr 3:136,119,113...136,131,223
G
Hadh
hydroxyacyl-CoA dehydrogenase
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:25741868 PMID:28492532 PMID:29280746 PMID:34055426 PMID:34547194
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
G
Insm1
INSM transcriptional repressor 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003
G
Kat14
lysine acetyltransferase 14
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,736,430...131,781,732
Ensembl chr 3:131,736,549...131,781,706
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:15580558 PMID:15718250 PMID:16885549 PMID:17466004 PMID:18414213 PMID:25741868 PMID:26448950 PMID:26467025 PMID:28492532 More...
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Kif16b
kinesin family member 16B
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
G
Kiz
kizuna centrosomal protein
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190
G
Mgme1
mitochondrial genome maintenance exonuclease 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932
G
Naa20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,322,036...133,336,843
Ensembl chr 3:133,322,064...133,337,009
G
Napb
NSF attachment protein beta
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,132,248...136,179,280
Ensembl chr 3:136,133,428...136,179,345
G
Nkx2-2
NK2 homeobox 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
G
Nkx2-4
NK2 homeobox 4
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:134,514,368...134,517,243
Ensembl chr 3:134,515,039...134,516,505
G
Nxt1
nuclear transport factor 2-like export factor 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:136,108,975...136,111,897
Ensembl chr 3:136,108,862...136,111,907
G
Otor
otoraplin
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:130,415,339...130,418,601
Ensembl chr 3:130,415,339...130,418,601
G
Ovol2
ovo-like zinc finger 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359
G
Pax1
paired box 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:134,792,330...134,801,637
Ensembl chr 3:134,789,182...134,801,636
G
Pcsk2
proprotein convertase subtilisin/kexin type 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
G
Pet117
PET117 cytochrome c oxidase chaperone
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
G
Polr3f
RNA polymerase III subunit F
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
G
Ralgapa2
Ral GTPase activating protein catalytic subunit alpha 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
G
Rbbp9
RB binding protein 9, serine hydrolase
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156
G
Rin2
Ras and Rab interactor 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:133,086,858...133,303,604
Ensembl chr 3:133,086,749...133,303,604
G
Rrbp1
ribosome binding protein 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
G
Scp2d1
SCP2 sterol-binding domain containing 1
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:132,201,979...132,202,729
Ensembl chr 3:132,200,744...132,212,725
G
Sec23b
Sec23 homolog B, COPII coat complex component
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,939,011...131,981,489
Ensembl chr 3:131,939,337...131,981,489
G
Slc24a3
solute carrier family 24 member 3
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:132,552,119...133,051,192
Ensembl chr 3:132,551,595...133,051,192
G
Snrpb2
small nuclear ribonucleoprotein polypeptide B2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
G
Snx5
sorting nexin 5
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192
G
Sstr4
somatostatin receptor 4
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
G
Thbd
thrombomodulin
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
G
Xrn2
5'-3' exoribonuclease 2
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:134,436,916...134,509,308
Ensembl chr 3:134,437,109...134,509,306
G
Zfp133
zinc finger protein 133
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1
ClinVar
PMID:38605124
NCBI chr 3:131,829,404...131,847,552
Ensembl chr 3:131,829,404...131,847,550
G
Abcc8
ATP binding cassette subfamily C member 8
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 2
ClinVar
PMID:9867219 PMID:11318841 PMID:11692183 PMID:11872696 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:15111507 PMID:15579791 PMID:15580558 PMID:15718250 PMID:15797964 PMID:15855351 PMID:16455067 PMID:17257281 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17823772 PMID:18414213 PMID:18758683 PMID:19214942 PMID:19233137 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20301620 PMID:20424228 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22264780 PMID:22591706 PMID:22701567 PMID:22704848 PMID:25741868 PMID:26448950 PMID:26467025 PMID:28492532 PMID:29893194 PMID:32935446 More...
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 2
ClinVar OMIM
PMID:7847376 PMID:8897013 PMID:8923010 PMID:9356020 PMID:9867219 PMID:10338089 PMID:10559219 PMID:11318841 PMID:11692183 PMID:11872696 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:14551916 PMID:14715863 PMID:14871556 PMID:15111507 PMID:15115830 PMID:15504982 PMID:15562009 PMID:15579781 PMID:15579791 PMID:15580558 PMID:15718250 PMID:15797964 PMID:15807877 PMID:15855351 PMID:15886397 PMID:15998776 PMID:16357843 PMID:16416420 PMID:16455067 PMID:16670688 PMID:17114887 PMID:17257281 PMID:17316607 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17673911 PMID:17823772 PMID:17956278 PMID:18250167 PMID:18290324 PMID:18414213 PMID:18596924 PMID:18758683 PMID:18767144 PMID:19214942 PMID:19233137 PMID:19357197 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20032456 PMID:20049716 PMID:20301620 PMID:20424228 PMID:20589481 PMID:20685672 PMID:20686794 PMID:20694718 PMID:20980454 PMID:21115269 PMID:21119644 PMID:21422196 PMID:21544516 PMID:21765448 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22264780 PMID:22311976 PMID:22471336 PMID:22512215 PMID:22591706 PMID:22701567 PMID:22704848 PMID:22958899 PMID:23226049 PMID:23275527 PMID:23345197 PMID:23700433 PMID:24018988 PMID:24383515 PMID:24401662 PMID:24421282 PMID:24434300 PMID:24686051 PMID:24698822 PMID:25247988 PMID:25555642 PMID:25637631 PMID:25639667 PMID:25741868 PMID:25871929 PMID:25972930 PMID:26448950 PMID:26467025 PMID:26545876 PMID:26740944 PMID:27118464 PMID:27188453 PMID:27908292 PMID:28123437 PMID:28352326 PMID:28442472 PMID:28492532 PMID:28938416 PMID:29216354 PMID:29893194 PMID:30026763 PMID:30297969 PMID:30377186 PMID:30873120 PMID:31291970 PMID:31464105 PMID:32027066 PMID:32935446 PMID:33324081 PMID:33762279 PMID:33853507 PMID:34737607 PMID:35402560 PMID:36208030 More...
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Gck
glucokinase
ISO ISS
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia familial 3 | ClinVar Annotator: match by term: Hyperinsulinism due to glucokinase deficiency OMIM:602485 CTD Direct Evidence: marker/mechanism
OMIM ClinVar MouseDO CTD
PMID:1502186 PMID:2555564 PMID:7553875 PMID:7555485 PMID:8068341 PMID:8325892 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8454109 PMID:8495817 PMID:9049484 PMID:9435328 PMID:9469993 PMID:9536098 PMID:9867845 PMID:10447526 PMID:10455021 PMID:10525657 PMID:11315850 PMID:11315851 PMID:11372010 PMID:11553210 PMID:11916951 PMID:11942313 PMID:12442280 PMID:12627330 PMID:14517946 PMID:14517956 PMID:14578306 PMID:14687251 PMID:15277402 PMID:15305805 PMID:15841481 PMID:15918042 PMID:15928245 PMID:15987895 PMID:16963153 PMID:16965331 PMID:17082186 PMID:17353190 PMID:17573900 PMID:17576681 PMID:17937063 PMID:18271687 PMID:19146401 PMID:19790256 PMID:20132997 PMID:20301620 PMID:20375417 PMID:21569204 PMID:21604084 PMID:21720051 PMID:21831042 PMID:22060211 PMID:22194744 PMID:22335469 PMID:22493702 PMID:22611063 PMID:23771925 PMID:24097065 PMID:24323243 PMID:24518839 PMID:24578721 PMID:24728127 PMID:24735133 PMID:25015100 PMID:25741868 PMID:25850297 PMID:26467025 PMID:27269892 PMID:27913849 PMID:28492532 PMID:29056535 PMID:29510678 PMID:30257192 PMID:31094068 PMID:31197960 PMID:31291970 PMID:31638168 PMID:31957151 PMID:32375122 PMID:32533152 PMID:32792356 PMID:33072637 PMID:33129248 PMID:33852230 PMID:34686905 PMID:34746319 PMID:35472491 PMID:36257325 PMID:37008541 More...
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Hadh
hydroxyacyl-CoA dehydrogenase
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 4 CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 4 | ClinVar Annotator: match by term: Hyperinsulinism due to glutamodehydrogenase deficiency
OMIM ClinVar CTD
PMID:904979 PMID:8825408 PMID:11489939 PMID:14693719 PMID:16725361 PMID:18414213 PMID:19318379 PMID:19417036 PMID:21252247 PMID:21347589 PMID:22579592 PMID:22662265 PMID:23273570 PMID:23275527 PMID:24686051 PMID:25741868 PMID:27104957 PMID:27771675 PMID:28492532 PMID:29280746 PMID:32876354 PMID:34055426 PMID:34547194 More...
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
G
Insr
insulin receptor
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 4 | ClinVar Annotator: match by term: Hyperinsulinism due to glutamodehydrogenase deficiency
ClinVar
PMID:2002058 PMID:2211730 PMID:2983222 PMID:7042734 PMID:8257688 PMID:8288049 PMID:15161766 PMID:19135752 PMID:23705494 PMID:25741868 PMID:26874853 PMID:27840822 PMID:27896077 PMID:28492532 PMID:30663027 PMID:31989990 PMID:35000900 More...
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
G
Insr
insulin receptor
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia familial 5 | ClinVar Annotator: match by term: Hyperinsulinism due to INSR deficiency CTD Direct Evidence: marker/mechanism
OMIM ClinVar CTD
PMID:2002058 PMID:2170418 PMID:2211730 PMID:2983222 PMID:7042734 PMID:8257688 PMID:8288049 PMID:15161766 PMID:19135752 PMID:23705494 PMID:25741868 PMID:26874853 PMID:27840822 PMID:27896077 PMID:28492532 PMID:30663027 PMID:31989990 PMID:35000900 More...
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
G
Glud1
glutamate dehydrogenase 1
ISO
ClinVar Annotator: match by term: Hyperinsulinism-hyperammonemia syndrome CTD Direct Evidence: marker/mechanism
OMIM ClinVar CTD
PMID:9469993 PMID:9536098 PMID:9571225 PMID:9571255 PMID:9843361 PMID:10636977 PMID:10871207 PMID:11214910 PMID:17576681 PMID:18414213 PMID:18928469 PMID:19046187 PMID:19344873 PMID:19690084 PMID:22730017 PMID:23506826 PMID:23869231 PMID:25008049 PMID:25741868 PMID:26467025 PMID:26759084 PMID:26839063 PMID:27188453 PMID:28165182 PMID:28492532 PMID:30252420 PMID:30306091 PMID:30352420 PMID:30425915 PMID:31119523 PMID:34992182 PMID:35951311 PMID:36239000 More...
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Shld2
shieldin complex subunit 2
ISO
ClinVar Annotator: match by term: Hyperinsulinism-hyperammonemia syndrome
ClinVar
PMID:25741868 PMID:26467025 PMID:28492532
NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
G
Slc16a1
solute carrier family 16 member 1
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Exercise-induced hyperinsulinism | ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia familial 7
OMIM CTD ClinVar
PMID:11207177 PMID:17701893 PMID:18414213 PMID:19881260 PMID:25371203 PMID:25741868 PMID:25741869 PMID:26595136 PMID:28492532 More...
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
G
Slc25a36
solute carrier family 25 member 36
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 8
OMIM ClinVar
PMID:34576089 PMID:34971397 PMID:36695547
NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
ISO ISS
ClinVar Annotator: match by term: HMG-CoA synthase-2 deficiency | ClinVar Annotator: match by term: MITOCHONDRIAL HMG-CoA SYNTHASE DEFICIENCY OMIM:605911 CTD Direct Evidence: marker/mechanism
OMIM ClinVar MouseDO CTD
PMID:9337379 PMID:9536098 PMID:9727719 PMID:11228257 PMID:11479731 PMID:12072887 PMID:12647205 PMID:16199547 PMID:17576681 PMID:20346956 PMID:23751782 PMID:25511235 PMID:25741868 PMID:28492532 PMID:29597274 PMID:30283815 PMID:30477625 PMID:31910233 PMID:32259399 PMID:32952630 PMID:33045405 PMID:35308163 More...
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
G
Phgdh
phosphoglycerate dehydrogenase
ISO
ClinVar Annotator: match by term: HMG-CoA synthase-2 deficiency
ClinVar
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
G
Abcc8
ATP binding cassette subfamily C member 8
ISS ISO
OMIM:256450 | OMIM:601820 | OMIM:602485 | OMIM:606762 | OMIM:609968 | OMIM:609975 | OMIM:610021 ClinVar Annotator: match by term: HYPERINSULINEMIC HYPOGLYCEMIA, PERSISTENT | ClinVar Annotator: match by term: HYPERINSULINISM, FAMILIAL, WITH PANCREATIC NESIDIOBLASTOSIS | ClinVar Annotator: match by term: Persistent Hyperinsulinemia Hypoglycemia of Infancy | ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy ClinVar Annotator: match by term: HYPERINSULINEMIC HYPOGLYCEMIA, PERSISTENT | ClinVar Annotator: match by term: HYPERINSULINISM, FAMILIAL, WITH PANCREATIC NESIDIOBLASTOSIS | ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia | ClinVar Annotator: match by term: Persistent Hyperinsulinemia Hypoglycemia of Infancy | ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy
MouseDO ClinVar
PMID:1021286 PMID:2198959 PMID:7716548 PMID:8650576 PMID:8751851 PMID:8923011 PMID:9382893 PMID:9519757 PMID:9536098 PMID:9568693 PMID:9618169 PMID:9648840 PMID:9769320 PMID:9867219 PMID:10194514 PMID:10202168 PMID:10204114 PMID:10334322 PMID:10338089 PMID:10400694 PMID:10426386 PMID:10447255 PMID:10487673 PMID:10685980 PMID:10720932 PMID:10923633 PMID:11226335 PMID:11272143 PMID:11318841 PMID:11395395 PMID:11692183 PMID:11867634 PMID:11872696 PMID:11999683 PMID:12169627 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:12941782 PMID:14692646 PMID:14715863 PMID:14764815 PMID:15111507 PMID:15356046 PMID:15466080 PMID:15562009 PMID:15579781 PMID:15579791 PMID:15797964 PMID:15855351 PMID:16186397 PMID:16199547 PMID:16357843 PMID:16380471 PMID:16416420 PMID:16429405 PMID:16442101 PMID:16455067 PMID:16613899 PMID:16860127 PMID:16882742 PMID:16885549 PMID:17257281 PMID:17378627 PMID:17384337 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17466004 PMID:17539904 PMID:17575084 PMID:17576681 PMID:17823772 PMID:18025408 PMID:18339976 PMID:18414213 PMID:18493152 PMID:18596924 PMID:18758683 PMID:18767144 PMID:18796520 PMID:18981553 PMID:18988933 PMID:19214942 PMID:19233137 PMID:19475716 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20301620 PMID:20424228 PMID:20427569 PMID:20573158 PMID:20672374 PMID:20685672 PMID:20799350 PMID:20849526 PMID:20943779 PMID:20943781 PMID:21378087 PMID:21422196 PMID:21674179 PMID:21716120 PMID:21835061 PMID:21851374 PMID:21968111 PMID:21978130 PMID:21989597 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22210575 PMID:22264780 PMID:22591706 PMID:22704848 PMID:22855730 PMID:22876564 PMID:23067144 PMID:23275527 PMID:23301914 PMID:23345197 PMID:23744072 PMID:24033266 PMID:24044690 PMID:24072082 PMID:24332968 PMID:24401662 PMID:24434300 PMID:24616771 PMID:24686051 PMID:25008049 PMID:25117148 PMID:25201519 PMID:25306193 PMID:25323548 PMID:25741868 PMID:25765446 PMID:25972930 PMID:26180531 PMID:26379717 PMID:26431509 PMID:26467025 PMID:26740944 PMID:27175728 PMID:27188453 PMID:27313609 PMID:27538677 PMID:27573238 PMID:27682711 PMID:27754802 PMID:27889714 PMID:27908292 PMID:28492532 PMID:28701683 PMID:29644095 PMID:29893194 PMID:30098243 PMID:30186238 PMID:30297969 PMID:30352420 PMID:30354297 PMID:30386300 PMID:30395892 PMID:30447144 PMID:30977832 PMID:31208162 PMID:31589614 PMID:31604004 PMID:31997554 PMID:32027066 PMID:32041611 PMID:32202736 PMID:32640185 PMID:32670376 PMID:32792356 PMID:32928245 PMID:33046911 PMID:33410562 PMID:34171966 PMID:34426522 PMID:34462253 PMID:34631896 PMID:34764980 PMID:34927408 PMID:36339418 More...
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Gck
glucokinase
ISS
OMIM:256450 | OMIM:601820 | OMIM:602485 | OMIM:606762 | OMIM:609968 | OMIM:609975 | OMIM:610021
MouseDO
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Hadh
hydroxyacyl-CoA dehydrogenase
ISO
ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia | ClinVar Annotator: match by term: Persistent Hyperinsulinemia Hypoglycemia of Infancy ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia | ClinVar Annotator: match by term: Persistent hyperinsulinemic hypoglycemia of infancy
ClinVar
PMID:8825408 PMID:16725361 PMID:19417036 PMID:21347589 PMID:23275527 PMID:25741868 PMID:27104957 PMID:27771675 PMID:28492532 PMID:29280746 PMID:32876354 PMID:34055426 PMID:34547194 More...
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: HYPERINSULINEMIC HYPOGLYCEMIA, PERSISTENT | ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia
ClinVar
PMID:9867219 PMID:10559219 PMID:11318841 PMID:11692183 PMID:11872696 PMID:12196481 PMID:12475776 PMID:12540637 PMID:12540638 PMID:14871556 PMID:15111507 PMID:15579791 PMID:15580558 PMID:15718250 PMID:15797964 PMID:15855351 PMID:15886397 PMID:16357843 PMID:16455067 PMID:16670688 PMID:17257281 PMID:17463246 PMID:17463248 PMID:17463249 PMID:17823772 PMID:18414213 PMID:18758683 PMID:19214942 PMID:19233137 PMID:19491206 PMID:19498446 PMID:19578796 PMID:19587354 PMID:19685080 PMID:20301620 PMID:20424228 PMID:21119644 PMID:21544516 PMID:21765448 PMID:22082043 PMID:22163043 PMID:22209866 PMID:22264780 PMID:22512215 PMID:22591706 PMID:22701567 PMID:22704848 PMID:23275527 PMID:24018988 PMID:24401662 PMID:25741868 PMID:25972930 PMID:26448950 PMID:26467025 PMID:27908292 PMID:28123437 PMID:28352326 PMID:28492532 PMID:29893194 PMID:30377186 PMID:32935446 More...
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Akt2
AKT serine/threonine kinase 2
ISO
ClinVar Annotator: match by term: Hypoinsulinemic hypoglycemia and body hemihypertrophy | ClinVar Annotator: match by term: Hypoinsulinemic hypoglycemia and hemihypertrophy CTD Direct Evidence: marker/mechanism
OMIM ClinVar CTD
PMID:15166380 PMID:16722806 PMID:21518566 PMID:21979934 PMID:25741868 PMID:28492532 More...
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
G
Abcc8
ATP binding cassette subfamily C member 8
ISO
ClinVar Annotator: match by term: Leucine-induced hypoglycemia | ClinVar Annotator: match by term: Leucine-sensitive hypoglycemia of infancy CTD Direct Evidence: marker/mechanism
OMIM ClinVar CTD
PMID:8650576 PMID:8923011 PMID:9382893 PMID:9648840 PMID:10204114 PMID:10426386 PMID:10685980 PMID:10857971 PMID:11867634 PMID:14692646 PMID:14715863 PMID:15356046 PMID:15466080 PMID:15562009 PMID:15579781 PMID:16357843 PMID:16380471 PMID:16416420 PMID:16429405 PMID:16442101 PMID:16613899 PMID:16882742 PMID:16885549 PMID:17378627 PMID:17466004 PMID:17539904 PMID:17823772 PMID:18025408 PMID:18414213 PMID:18596924 PMID:18796520 PMID:18981553 PMID:19475716 PMID:19766903 PMID:20685672 PMID:20799350 PMID:20849526 PMID:20943781 PMID:21142918 PMID:21378087 PMID:21422196 PMID:21674179 PMID:21814221 PMID:21989597 PMID:22151254 PMID:22210575 PMID:22533711 PMID:23067144 PMID:23275527 PMID:23301914 PMID:23345197 PMID:23563683 PMID:24332968 PMID:24401662 PMID:24434300 PMID:25008049 PMID:25117148 PMID:25741868 PMID:25765446 PMID:25871929 PMID:25972930 PMID:26180531 PMID:26379717 PMID:26431509 PMID:26467025 PMID:26740944 PMID:27538677 PMID:27573238 PMID:27677908 PMID:28492532 PMID:28587604 PMID:28757749 PMID:29644095 PMID:29751826 PMID:30098243 PMID:30297969 PMID:30447144 PMID:30515958 PMID:30977832 PMID:31110826 PMID:31604004 PMID:32027066 PMID:32041611 PMID:32640185 PMID:32670376 PMID:32792356 PMID:32928245 PMID:33400071 PMID:34171966 PMID:34194474 PMID:34426522 PMID:34462253 PMID:34777243 PMID:36339418 More...
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: Leucine-induced hypoglycemia
ClinVar
PMID:16885549 PMID:17466004 PMID:25741868 PMID:28492532
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
G
Abcc8
ATP binding cassette subfamily C member 8
ISO
ClinVar Annotator: match by term: Neonatal hypoglycemia
ClinVar
PMID:10857971 PMID:16885549 PMID:17466004 PMID:21814221 PMID:25741868 PMID:26467025 PMID:28492532 More...
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Akt2
AKT serine/threonine kinase 2
ISO
ClinVar Annotator: match by term: Hypoglycemia, neonatal, simulating foetopathia diabetica
ClinVar
PMID:15166380 PMID:16722806 PMID:21518566 PMID:25741868 PMID:28492532
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
G
Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
ISO
ClinVar Annotator: match by term: Neonatal hypoglycemia
ClinVar
PMID:16609879 PMID:16885549 PMID:17446535 PMID:17466004 PMID:17635943 PMID:18073297 PMID:18414213 PMID:20301620 PMID:21340152 PMID:23226037 PMID:25741868 PMID:26388896 PMID:27223594 PMID:28492532 PMID:30286572 More...
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all