Gene: Pcsk2 (proprotein convertase subtilisin/kexin type 2) Rattus norvegicus
Symbol: Pcsk2
Name: proprotein convertase subtilisin/kexin type 2
Description: ENCODES a protein that exhibits protein complex binding; serine-type endopeptidase activity; endopeptidase activity (ortholog); INVOLVED IN islet amyloid polypeptide processing; peptide hormone processing; proteolysis; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Endotoxemia; Inflammation; FOUND IN dendrite; neuronal cell body; perikaryon; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: KEX2-like endoprotease 2; NEC 2; neuroendocrine convertase 2; PC2; prohormone convertase 2; proprotein convertase 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03137,618,891 - 137,923,385 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.03144,059,121 - 144,362,761 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.43131,925,648 - 132,256,178 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13131,831,220 - 132,161,751 (+)NCBI
Celera3129,792,699 - 130,080,973 (+)NCBI
Cytogenetic Map3q42NCBImapview
RH 3.4 Map31176.7RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcsk2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3273
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-04-12
Status: ACTIVE