Gene: Pcsk2 (proprotein convertase subtilisin/kexin type 2) Rattus norvegicus
Symbol: Pcsk2
Name: proprotein convertase subtilisin/kexin type 2
Description: ENCODES a protein that exhibits protein complex binding; serine-type endopeptidase activity; endopeptidase activity (ortholog); INVOLVED IN islet amyloid polypeptide processing; peptide hormone processing; proteolysis; PARTICIPATES IN melanocortin system pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Endotoxemia; Inflammation; FOUND IN dendrite; neuronal cell body; perikaryon; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: KEX2-like endoprotease 2; NEC 2; neuroendocrine convertase 2; PC2; prohormone convertase 2; proprotein convertase 2
Orthologs:
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.03137,618,891 - 137,923,385+NCBI
Rat Cytogenetic Map3q42 NCBI
RGSC Genome Assembly v5.03144,059,121 - 144,362,761+NCBI
RGSC Genome Assembly v3.43131,925,648 - 132,256,178+NCBI
Rat Celera Assembly3129,792,699 - 130,080,973+NCBI
Genome Assembly 3.13131,831,220 - 132,161,751+NCBI
RH 3.431176.7 RGD
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcsk2
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3273
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-10-14
Status: ACTIVE