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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zinc acetate
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Accession:CHEBI:62984 term browser browse the term
Definition:An acetate salt in which the cationic component is zinc(2+).
Synonyms:related_synonym: Acetic acid, zinc salt (2:1);   Acetic acid, zinc(II) salt;   Dicarbomethoxyzinc;   Formula=C4H6O4Zn;   InChI=1S/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2;   InChIKey=DJWUNCQRNNEAKC-UHFFFAOYSA-L;   SMILES=[Zn++].CC([O-])=O.CC([O-])=O;   Zinc acetate anhydrous;   Zinc di(acetate);   Zinc(II) acetate;   Zn(II)Ac2;   Zn(OAc)2;   acetic acid, zinc salt;   zinc diacetate
 xref: CAS:557-34-6
 xref_mesh: MESH:D019345
 xref: PMID:20634118;   PMID:21109379;   PMID:21381680;   Reaxys:3563830


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zinc acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA CTD PMID:26241054 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of AGL mRNA
Zinc Acetate results in decreased expression of AGL mRNA		 CTD PMID:16357179 NCBI chr 1:99,849,258...99,924,023
Ensembl chr 1:99,850,361...99,924,023 		JBrowse link
G ALAD aminolevulinate dehydratase increases activity
multiple interactions		 ISO Zinc Acetate results in increased activity of ALAD protein
[Zinc Acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; Zinc Acetate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein]		 CTD PMID:21360559 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 multiple interactions
increases expression		 EXP motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of ALDH5A1 mRNA] CTD PMID:16357179 NCBI chr 6:24,494,969...24,537,207
Ensembl chr 6:24,494,867...24,537,207 		JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 multiple interactions
increases expression		 EXP Zinc Acetate inhibits the reaction [motexafin gadolinium results in decreased expression of ALDH6A1 mRNA]
Zinc Acetate results in increased expression of ALDH6A1 mRNA		 CTD PMID:16357179 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492 		JBrowse link
G ARHGAP17 Rho GTPase activating protein 17 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ARHGAP17 mRNA
Zinc Acetate results in decreased expression of ARHGAP17 mRNA		 CTD PMID:16357179 NCBI chr16:24,919,389...25,015,369
Ensembl chr16:24,919,389...25,015,666 		JBrowse link
G ATF3 activating transcription factor 3 multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of ATF3 mRNA] CTD PMID:16357179 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATM ATM serine/threonine kinase multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA] CTD PMID:16357179 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP7B ATPase copper transporting beta increases response to substance
multiple interactions		 ISO ATP7B gene mutant form results in increased susceptibility to Zinc Acetate
[ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA		 CTD PMID:26241054 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G ATR ATR serine/threonine kinase multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ATR mRNA
Zinc Acetate results in decreased expression of ATR mRNA		 CTD PMID:16357179 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733 		JBrowse link
G BACH1 BTB domain and CNC homolog 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BACH1 mRNA
Zinc Acetate results in increased expression of BACH1 mRNA		 CTD PMID:16357179 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751 		JBrowse link
G BAG3 BAG cochaperone 3 multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of BAG3 mRNA] CTD PMID:16357179 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions EXP [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of BIRC5 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]		 CTD PMID:16357179 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BMT2 base methyltransferase of 25S rRNA 2 homolog multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BMT2 mRNA
Zinc Acetate results in increased expression of BMT2 mRNA		 CTD PMID:16357179 NCBI chr 7:112,819,147...112,939,875
Ensembl chr 7:112,819,147...112,939,875 		JBrowse link
G BNIP3 BCL2 interacting protein 3 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3 mRNA
Zinc Acetate results in increased expression of BNIP3 mRNA		 CTD PMID:16357179 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3L mRNA
Zinc Acetate results in increased expression of BNIP3L mRNA		 CTD PMID:16357179 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636 		JBrowse link
G BSG basigin (Ok blood group) multiple interactions ISO [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BSG protein] CTD PMID:34508822 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G CANX calnexin increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of CANX mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CANX mRNA		 CTD PMID:16357179 NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641 		JBrowse link
G CASP3 caspase 3 multiple interactions
decreases expression		 ISO
EXP		 [Taurine co-treated with Zinc Acetate] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
Zinc Acetate results in decreased expression of CASP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CASP3 mRNA		 CTD PMID:16357179 PMID:26335259 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CBFB core-binding factor subunit beta increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of CBFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CBFB mRNA		 CTD PMID:16357179 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058 		JBrowse link
G CCNB1 cyclin B1 multiple interactions EXP [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCNB1 protein] CTD PMID:36162444 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCNJ cyclin J multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CCNJ mRNA
Zinc Acetate results in decreased expression of CCNJ mRNA		 CTD PMID:16357179 NCBI chr10:96,043,068...96,060,870
Ensembl chr10:96,043,394...96,060,870 		JBrowse link
G CDC16 cell division cycle 16 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC16 mRNA
Zinc Acetate results in decreased expression of CDC16 mRNA		 CTD PMID:16357179 NCBI chr13:114,234,897...114,272,723
Ensembl chr13:114,234,887...114,272,723 		JBrowse link
G CDC25C cell division cycle 25C multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDC25C mRNA
Zinc Acetate results in increased expression of CDC25C mRNA		 CTD PMID:16357179 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDC27 cell division cycle 27 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of CDC27 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CDC27 mRNA		 CTD PMID:16357179 NCBI chr17:47,117,703...47,189,295
Ensembl chr17:47,117,703...47,189,422 		JBrowse link
G CDC5L cell division cycle 5 like decreases expression
multiple interactions		 EXP Zinc Acetate results in decreased expression of CDC5L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC5L mRNA		 CTD PMID:16357179 NCBI chr 6:44,387,706...44,450,425
Ensembl chr 6:44,387,706...44,450,425 		JBrowse link
G CDCA2 cell division cycle associated 2 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDCA2 mRNA
Zinc Acetate results in decreased expression of CDCA2 mRNA		 CTD PMID:16357179 NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911 		JBrowse link
G CDK19 cyclin dependent kinase 19 increases expression EXP Zinc Acetate results in increased expression of CDK19 mRNA CTD PMID:16357179 NCBI chr 6:110,609,978...110,815,855
Ensembl chr 6:110,609,978...110,815,958 		JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions
increases expression		 EXP motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA] CTD PMID:16357179 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] CTD PMID:20530418 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDKN1B mRNA
Zinc Acetate results in increased expression of CDKN1B mRNA		 CTD PMID:16357179 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CTH cystathionine gamma-lyase increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of CTH mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CTH mRNA		 CTD PMID:16357179 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G CUL3 cullin 3 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CUL3 mRNA
Zinc Acetate results in decreased expression of CUL3 mRNA		 CTD PMID:16357179 NCBI chr 2:224,470,150...224,585,363
Ensembl chr 2:224,470,150...224,585,397 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases secretion EXP Zinc Acetate results in increased secretion of CXCL1 protein CTD PMID:21974847 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases secretion
increases expression		 EXP 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]
Zinc Acetate results in increased secretion of CXCL8 protein		 CTD PMID:21974847 PMID:24080332 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYB5R1 cytochrome b5 reductase 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of CYB5R1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CYB5R1 mRNA		 CTD PMID:16357179 NCBI chr 1:202,961,873...202,967,257
Ensembl chr 1:202,961,873...202,967,275 		JBrowse link
G DAPK3 death associated protein kinase 3 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of DAPK3 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA]		 CTD PMID:16357179 NCBI chr19:3,958,453...3,971,099
Ensembl chr19:3,958,453...3,971,123 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DDIT3 mRNA] CTD PMID:16357179 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of DDIT4 mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of DDIT4 mRNA] CTD PMID:16357179 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DEDD2 death effector domain containing 2 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of DEDD2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DEDD2 mRNA]		 CTD PMID:16357179 NCBI chr19:42,198,598...42,220,134
Ensembl chr19:42,198,598...42,220,140 		JBrowse link
G DFFB DNA fragmentation factor subunit beta multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of DFFB mRNA
Zinc Acetate results in decreased expression of DFFB mRNA		 CTD PMID:16357179 NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase decreases expression EXP Zinc Acetate results in decreased expression of DHCR7 mRNA CTD PMID:16357179 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
multiple interactions		 EXP Zinc Acetate results in decreased expression of DNAJB1 mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in decreased expression of DNAJB1 mRNA]		 CTD PMID:16357179 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB4 mRNA
Zinc Acetate results in increased expression of DNAJB4 mRNA		 CTD PMID:16357179 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB6 mRNA
Zinc Acetate results in increased expression of DNAJB6 mRNA		 CTD PMID:16357179 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439 		JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
increases expression		 EXP motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of DNAJC3 mRNA] CTD PMID:16357179 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988 		JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO Zinc Acetate inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 multiple interactions ISO Zinc Acetate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein] CTD PMID:9109525 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 mRNA; [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 protein CTD PMID:26335259 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G E2F1 E2F transcription factor 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of E2F1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA		 CTD PMID:16357179 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F3 E2F transcription factor 3 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F3 mRNA
Zinc Acetate results in increased expression of E2F3 mRNA		 CTD PMID:16357179 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of EGLN1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of EGLN1 mRNA		 CTD PMID:16357179 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ELP1 mRNA
Zinc Acetate results in decreased expression of ELP1 mRNA		 CTD PMID:16357179 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328 		JBrowse link
G ENO1 enolase 1 increases expression EXP Zinc Acetate results in increased expression of ENO1 mRNA CTD PMID:16357179 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G FADD Fas associated via death domain multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FADD mRNA
Zinc Acetate results in decreased expression of FADD mRNA		 CTD PMID:16357179 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FAIM Fas apoptotic inhibitory molecule multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FAIM mRNA
Zinc Acetate results in decreased expression of FAIM mRNA		 CTD PMID:16357179 NCBI chr 3:138,608,771...138,633,376
Ensembl chr 3:138,608,606...138,633,376 		JBrowse link
G FAM162A family with sequence similarity 162 member A increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of FAM162A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FAM162A mRNA		 CTD PMID:16357179 NCBI chr 3:122,384,182...122,412,334
Ensembl chr 3:122,384,161...122,412,334 		JBrowse link
G FASN fatty acid synthase decreases expression EXP Zinc Acetate results in decreased expression of FASN mRNA CTD PMID:16357179 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FOXO3 mRNA
Zinc Acetate results in increased expression of FOXO3 mRNA		 CTD PMID:16357179 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of GCLM mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA		 CTD PMID:16357179 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GLS glutaminase multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GLS mRNA
Zinc Acetate results in decreased expression of GLS mRNA		 CTD PMID:16357179 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552 		JBrowse link
G GPR146 G protein-coupled receptor 146 increases expression EXP Zinc Acetate results in increased expression of GPR146 mRNA CTD PMID:16357179 NCBI chr 7:1,044,546...1,059,261
Ensembl chr 7:1,044,546...1,059,261 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 increases expression EXP Zinc Acetate results in increased expression of GPT2 mRNA CTD PMID:16357179 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA] CTD PMID:20530418 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
increases expression		 EXP
ISO		 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GSR mRNA
Zinc Acetate results in decreased activity of GSR protein
Zinc Acetate results in increased expression of GSR mRNA		 CTD PMID:16357179 PMID:17382203 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GTF3C2 general transcription factor IIIC subunit 2 increases expression EXP Zinc Acetate results in increased expression of GTF3C2 mRNA CTD PMID:16357179 NCBI chr 2:27,325,854...27,356,764
Ensembl chr 2:27,325,849...27,356,999 		JBrowse link
G HBP1 HMG-box transcription factor 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of HBP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HBP1 mRNA		 CTD PMID:16357179 NCBI chr 7:107,169,003...107,202,522
Ensembl chr 7:107,168,961...107,202,522 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression		 EXP [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein
Zinc Acetate results in increased expression of HIF1A protein		 CTD PMID:16357179 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HILPDA mRNA
Zinc Acetate results in increased expression of HILPDA mRNA		 CTD PMID:16357179 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HIPK1 mRNA] CTD PMID:16357179 NCBI chr 1:113,929,324...113,977,869
Ensembl chr 1:113,929,324...113,977,869 		JBrowse link
G HLTF helicase like transcription factor multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of HLTF mRNA
Zinc Acetate results in decreased expression of HLTF mRNA		 CTD PMID:16357179 NCBI chr 3:149,030,063...149,086,533
Ensembl chr 3:149,030,127...149,086,554 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 EXP
ISO		 [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HMOX1 protein; motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HMOX1 mRNA]
[Taurine co-treated with Zinc Acetate] results in increased expression of HMOX1 protein		 CTD PMID:16357179 PMID:26335259 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HRK harakiri, BCL2 interacting protein increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of HRK mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HRK mRNA		 CTD PMID:16357179 NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA
Zinc Acetate results in increased expression of HSP90AB1 mRNA		 CTD PMID:16357179 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1A mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1A mRNA] CTD PMID:16357179 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1B mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1B mRNA] CTD PMID:16357179 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4 mRNA
Zinc Acetate results in increased expression of HSPA4 mRNA		 CTD PMID:16357179 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPA4L heat shock protein family A (Hsp70) member 4 like multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4L mRNA
Zinc Acetate results in increased expression of HSPA4L mRNA		 CTD PMID:16357179 NCBI chr 4:127,781,796...127,840,733
Ensembl chr 4:127,781,821...127,840,733 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPB1 mRNA] CTD PMID:16357179 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPD1 mRNA] CTD PMID:16357179 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPH1 mRNA] CTD PMID:16357179 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
increases expression		 EXP 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; [Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein] CTD PMID:24080332 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID2 inhibitor of DNA binding 2 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of ID2 mRNA
Zinc Acetate results in increased expression of ID2 mRNA		 CTD PMID:16357179 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IKBKE mRNA
Zinc Acetate results in increased expression of IKBKE mRNA		 CTD PMID:16357179 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IL10 interleukin 10 increases secretion EXP Zinc Acetate results in increased secretion of IL10 protein CTD PMID:21974847 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of IL1B protein CTD PMID:27501764 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases secretion EXP Zinc Acetate results in increased secretion of IL6 protein CTD PMID:21974847 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 increases secretion EXP Zinc Acetate results in increased secretion of IL7 protein CTD PMID:21974847 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IRF2BP2 mRNA
Zinc Acetate results in increased expression of IRF2BP2 mRNA		 CTD PMID:16357179 NCBI chr 1:234,604,269...234,610,178
Ensembl chr 1:234,604,269...234,610,178 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of JUND mRNA
Zinc Acetate results in increased expression of JUND mRNA		 CTD PMID:16357179 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KDM3A lysine demethylase 3A increases expression EXP Zinc Acetate results in increased expression of KDM3A mRNA CTD PMID:16357179 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK9 protein modified form CTD PMID:27501764 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MAPT microtubule associated protein tau multiple interactions EXP [Zinc Acetate results in decreased abundance of Copper] which results in decreased phosphorylation of MAPT protein CTD PMID:25671100 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MDM2 MDM2 proto-oncogene multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] CTD PMID:16357179 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MOB1A MOB kinase activator 1A increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of MOB1A mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MOB1A mRNA]		 CTD PMID:16357179 NCBI chr 2:74,152,528...74,178,879
Ensembl chr 2:74,152,528...74,178,898 		JBrowse link
G MT1E metallothionein 1E increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of MT1E mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of MT1E mRNA		 CTD PMID:16357179 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1F metallothionein 1F multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MT1F mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of MT1F mRNA] CTD PMID:16357179 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698 		JBrowse link
G MT1G metallothionein 1G multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1G mRNA] CTD PMID:16357179 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065 		JBrowse link
G MT1H metallothionein 1H multiple interactions
increases expression		 EXP motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1H mRNA] CTD PMID:16357179 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129 		JBrowse link
G MT1HL1 metallothionein 1H like 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of MT1HL1 mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1HL1 mRNA]		 CTD PMID:16357179 NCBI chr 1:237,004,103...237,004,441
Ensembl chr 1:237,004,103...237,004,441 		JBrowse link
G MT1X metallothionein 1X multiple interactions
increases expression		 EXP
ISO		 motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1X mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of MT1X mRNA]
Zinc Acetate results in increased expression of MT1 protein		 CTD PMID:15306638 PMID:16357179 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A increases expression
multiple interactions		 ISO
EXP		 Zinc Acetate results in increased expression of MT2 mRNA; Zinc Acetate results in increased expression of MT2 protein
Zinc Acetate results in increased expression of MT2A mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT2A mRNA]		 CTD PMID:8876661 PMID:15306638 PMID:16357179 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]
Zinc Acetate results in decreased expression of MYD88 mRNA		 CTD PMID:16357179 PMID:24080332 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NADK NAD kinase multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NADK mRNA
Zinc Acetate results in increased expression of NADK mRNA		 CTD PMID:16357179 NCBI chr 1:1,751,232...1,780,514
Ensembl chr 1:1,751,232...1,780,457 		JBrowse link
G NF1 neurofibromin 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of NF1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NF1 mRNA		 CTD PMID:16357179 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases degradation
multiple interactions
increases phosphorylation		 EXP Zinc Acetate results in increased degradation of NFKBIA protein
[Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]		 CTD PMID:21974847 PMID:24080332 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NISCH nischarin decreases expression EXP Zinc Acetate results in decreased expression of NISCH mRNA CTD PMID:16357179 NCBI chr 3:52,455,604...52,493,068
Ensembl chr 3:52,455,118...52,493,068 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA CTD PMID:26241054 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1D2 nuclear receptor subfamily 1 group D member 2 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of NR1D2 mRNA] CTD PMID:16357179 NCBI chr 3:23,945,286...23,980,617
Ensembl chr 3:23,945,286...23,980,617 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter] CTD PMID:26241054 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of P4HB mRNA] CTD PMID:16357179 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PDCD11 programmed cell death 11 decreases expression EXP Zinc Acetate results in decreased expression of PDCD11 mRNA CTD PMID:16357179 NCBI chr10:103,396,626...103,446,294
Ensembl chr10:103,396,626...103,446,294 		JBrowse link
G PDCD4 programmed cell death 4 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PDCD4 mRNA
Zinc Acetate results in increased expression of PDCD4 mRNA		 CTD PMID:16357179 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006 		JBrowse link
G PDCD5 programmed cell death 5 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PDCD5 mRNA
Zinc Acetate results in decreased expression of PDCD5 mRNA		 CTD PMID:16357179 NCBI chr19:32,581,190...32,587,453
Ensembl chr19:32,581,190...32,587,453 		JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB3 mRNA
Zinc Acetate results in increased expression of PFKFB3 mRNA		 CTD PMID:16357179 NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644 		JBrowse link
G PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA
Zinc Acetate results in increased expression of PFKFB4 mRNA		 CTD PMID:16357179 NCBI chr 3:48,517,684...48,563,136
Ensembl chr 3:48,517,684...48,562,015 		JBrowse link
G PFKM phosphofructokinase, muscle multiple interactions ISO [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of PFKM protein] CTD PMID:34508822 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404 		JBrowse link
G PGK1 phosphoglycerate kinase 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of PGK1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PGK1 mRNA]		 CTD PMID:16357179 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PHTF2 putative homeodomain transcription factor 2 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PHTF2 mRNA] CTD PMID:16357179 NCBI chr 7:77,798,773...77,957,504
Ensembl chr 7:77,798,773...77,957,503 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PIAS1 mRNA] CTD PMID:16357179 NCBI chr15:68,054,315...68,193,847
Ensembl chr15:68,054,309...68,198,603 		JBrowse link
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PIK3IP1 mRNA
Zinc Acetate results in increased expression of PIK3IP1 mRNA		 CTD PMID:16357179 NCBI chr22:31,281,593...31,292,534
Ensembl chr22:31,281,594...31,292,534 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of PMAIP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PMAIP1 mRNA		 CTD PMID:16357179 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PRKACB mRNA
Zinc Acetate results in increased expression of PRKACB mRNA		 CTD PMID:16357179 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G PRKCD protein kinase C delta decreases expression EXP Zinc Acetate results in decreased expression of PRKCD mRNA CTD PMID:16357179 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKD2 protein kinase D2 decreases expression EXP Zinc Acetate results in decreased expression of PRKD2 mRNA CTD PMID:16357179 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit increases expression EXP Zinc Acetate results in increased expression of PRKDC mRNA CTD PMID:16357179 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PTRH2 peptidyl-tRNA hydrolase 2 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PTRH2 mRNA
Zinc Acetate results in decreased expression of PTRH2 mRNA		 CTD PMID:16357179 NCBI chr17:59,697,308...59,707,430
Ensembl chr17:59,674,636...59,707,626 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin multiple interactions EXP [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PTTG1 protein] CTD PMID:36162444 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G RB1 RB transcriptional corepressor 1 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA
Zinc Acetate results in decreased expression of RB1 mRNA		 CTD PMID:16357179 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RCBTB2 RCC1 and BTB domain containing protein 2 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RCBTB2 mRNA
Zinc Acetate results in decreased expression of RCBTB2 mRNA		 CTD PMID:16357179 NCBI chr13:48,488,963...48,535,895
Ensembl chr13:48,488,963...48,533,256 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of RELB mRNA
Zinc Acetate results in increased expression of RELB mRNA		 CTD PMID:16357179 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RXRA retinoid X receptor alpha multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA CTD PMID:26241054 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SELENOW selenoprotein W multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SELENOW mRNA
Zinc Acetate results in increased expression of SELENOW mRNA		 CTD PMID:16357179 NCBI chr19:47,778,703...47,784,682
Ensembl chr19:47,778,677...47,784,686 		JBrowse link
G SESN2 sestrin 2 multiple interactions
increases expression		 EXP [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]
Zinc Acetate results in increased expression of SESN2 mRNA		 CTD PMID:16357179 PMID:20530418 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC16A1 mRNA] CTD PMID:16357179 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593 		JBrowse link
G SLC16A3 solute carrier family 16 member 3 multiple interactions ISO [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of SLC16A3 protein] CTD PMID:34508822 NCBI chr17:82,217,934...82,240,086
Ensembl chr17:82,217,934...82,261,129 		JBrowse link
G SLC16A6 solute carrier family 16 member 6 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of SLC16A6 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC16A6 mRNA		 CTD PMID:16357179 NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267 		JBrowse link
G SLC1A4 solute carrier family 1 member 4 increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of SLC1A4 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC1A4 mRNA]		 CTD PMID:16357179 NCBI chr 2:64,988,479...65,023,865
Ensembl chr 2:64,988,477...65,023,865 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions ISO [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SLC2A1 protein] CTD PMID:34508822 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC30A1 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC30A1 mRNA] CTD PMID:16357179 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 increases expression EXP Zinc Acetate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC38A2 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC38A2 mRNA] CTD PMID:16357179 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SLC39A10 solute carrier family 39 member 10 affects expression
multiple interactions		 EXP Zinc Acetate affects the expression of SLC39A10 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A10 mRNA		 CTD PMID:16357179 NCBI chr 2:195,613,029...195,737,700
Ensembl chr 2:195,575,977...195,737,702 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A14 mRNA
Zinc Acetate results in increased expression of SLC39A14 mRNA		 CTD PMID:16357179 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129 		JBrowse link
G SLC39A9 solute carrier family 39 member 9 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC39A9 mRNA
Zinc Acetate results in increased expression of SLC39A9 mRNA		 CTD PMID:16357179 NCBI chr14:69,398,384...69,462,390
Ensembl chr14:69,398,015...69,462,390 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC3A2 mRNA
Zinc Acetate results in increased expression of SLC3A2 mRNA		 CTD PMID:16357179 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SLC43A1 solute carrier family 43 member 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC43A1 mRNA
Zinc Acetate results in increased expression of SLC43A1 mRNA		 CTD PMID:16357179 NCBI chr11:57,484,534...57,515,702
Ensembl chr11:57,484,534...57,515,780 		JBrowse link
G SLC7A1 solute carrier family 7 member 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A1 mRNA
Zinc Acetate results in increased expression of SLC7A1 mRNA		 CTD PMID:16357179 NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA
Zinc Acetate results in increased expression of SLC7A11 mRNA		 CTD PMID:16357179 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA4 mRNA
Zinc Acetate results in decreased expression of SMARCA4 mRNA		 CTD PMID:16357179 NCBI chr19:10,961,030...11,062,273
Ensembl chr19:10,960,932...11,079,426 		JBrowse link
G SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA5 mRNA
Zinc Acetate results in decreased expression of SMARCA5 mRNA		 CTD PMID:16357179 NCBI chr 4:143,513,702...143,557,486
Ensembl chr 4:143,513,702...143,557,486 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO [Zinc Acetate results in increased abundance of Zinc] inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of SOD1 protein] CTD PMID:34508822 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SP1 Sp1 transcription factor increases expression EXP Zinc Acetate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TAGAP mRNA
Zinc Acetate results in increased expression of TAGAP mRNA		 CTD PMID:16357179 NCBI chr 6:159,034,481...159,044,991
Ensembl chr 6:159,034,468...159,095,823 		JBrowse link
G TFRC transferrin receptor multiple interactions
increases expression		 EXP motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of TFRC mRNA] CTD PMID:16357179 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TNFAIP8 TNF alpha induced protein 8 decreases expression
multiple interactions		 EXP Zinc Acetate results in decreased expression of TNFAIP8 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFAIP8 mRNA		 CTD PMID:16357179 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF10B mRNA
Zinc Acetate results in increased expression of TNFRSF10B mRNA		 CTD PMID:16357179 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF17 TNF receptor superfamily member 17 multiple interactions
decreases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFRSF17 mRNA
Zinc Acetate results in decreased expression of TNFRSF17 mRNA		 CTD PMID:16357179 NCBI chr16:11,965,210...11,968,068
Ensembl chr16:11,965,210...11,968,068 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of TNFRSF1A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF1A mRNA		 CTD PMID:16357179 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF8 TNF superfamily member 8 multiple interactions
increases expression		 EXP motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of TNFSF8 mRNA] CTD PMID:16357179 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 decreases expression EXP Zinc Acetate results in decreased expression of TNIP2 mRNA CTD PMID:16357179 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein] CTD PMID:20530418 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRIB3 tribbles pseudokinase 3 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TRIB3 mRNA
Zinc Acetate results in increased expression of TRIB3 mRNA		 CTD PMID:16357179 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G TXNRD1 thioredoxin reductase 1 multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TXNRD1 mRNA
Zinc Acetate results in increased expression of TXNRD1 mRNA		 CTD PMID:16357179 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in increased expression of UGT2B1 mRNA CTD PMID:26335259 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression		 EXP [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of VEGFA mRNA
Zinc Acetate results in increased expression of VEGFA mRNA		 CTD PMID:16357179 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor increases expression
multiple interactions		 EXP Zinc Acetate results in increased expression of VHL mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of VHL mRNA]		 CTD PMID:16357179 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667 		JBrowse link
G ZNF200 zinc finger protein 200 decreases expression EXP Zinc Acetate results in decreased expression of ZNF200 mRNA CTD PMID:16357179 NCBI chr16:3,222,325...3,235,158
Ensembl chr16:3,222,325...3,236,221 		JBrowse link
G ZNF302 zinc finger protein 302 increases expression EXP Zinc Acetate results in increased expression of ZNF302 mRNA CTD PMID:16357179 NCBI chr19:34,675,979...34,686,396
Ensembl chr19:34,677,639...34,686,397 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      application 25177
        pharmaceutical 24551
          drug 24548
            astringent 12086
              zinc acetate 171
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  group 25882
                    polyatomic entity 25882
                      heteroatomic molecular entity 25533
                        salt 17499
                          organic salt 3410
                            acetate salt 217
                              zinc acetate 171
paths to the root