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Gene: Smurf1 (SMAD specific E3 ubiquitin protein ligase 1) Rattus norvegicus

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Symbol:

Smurf1

Name:

SMAD specific E3 ubiquitin protein ligase 1

RGD ID:

1594738

Description:

Predicted to enable SMAD binding activity; signaling receptor binding activity; and ubiquitin protein ligase activity. Involved in positive regulation of axon extension. Located in axon and neuronal cell body. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E3 ubiquitin-protein ligase SMURF1; LOC690516; RGD1309707; similar to Smad ubiquitination regulatory factor 1 isoform 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	14,748,717 - 14,840,273 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	14,749,043 - 14,840,273 (+)	Ensembl				GRCr8
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	9,635,025 - 9,726,519 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	10,438,588 - 10,530,424 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	11,061,801 - 11,153,638 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	10,086,150 - 10,176,124 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	11,433,815 - 11,526,465 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	11,407,213 - 11,526,465 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	13,499,018 - 13,591,105 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	9,950,304 - 10,042,391 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	11,439,779 - 11,530,606 (+)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cocaine-Related Disorders (ISO)

pancreatic cancer (ISO)

Spinal Cord Injuries (IEP)

withdrawal disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,3-dinitrobenzene (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cocaine (EXP)

curcumin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

divanadium pentaoxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

folic acid (ISO)

formaldehyde (ISO)

genistein (ISO)

glycerol 2-phosphate (ISO)

irinotecan (ISO)

L-ascorbic acid (ISO)

methapyrilene (ISO)

methimazole (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nickel atom (EXP)

nickel sulfate (EXP)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tacrolimus hydrate (ISO)

testosterone (EXP,ISO)

tetrachloromethane (ISO)

thiram (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (ISO)

BMP signaling pathway (IEA,ISO)

cell differentiation (IEA,ISO)

defense response to virus (ISO)

ectoderm development (IEA)

engulfment of target by autophagosome (IEA,ISO)

negative regulation of activin receptor signaling pathway (IEA,ISO)

negative regulation of BMP signaling pathway (IBA,IEA,ISO)

negative regulation of ossification (ISO)

negative regulation of transforming growth factor beta receptor signaling pathway (IEA,ISO)

positive regulation of axon extension (IMP)

positive regulation of dendrite extension (IEA,ISO)

positive regulation of ubiquitin-dependent protein catabolic process (IEA,ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA,IEA,ISO)

protein catabolic process (ISO)

protein export from nucleus (IEA,ISO)

protein K63-linked ubiquitination (ISO)

protein localization to plasma membrane (IEA,ISO)

protein polyubiquitination (IEA,ISO)

protein targeting to vacuole involved in autophagy (IEA,ISO)

protein ubiquitination (IEA,ISO)

receptor catabolic process (IEA,ISO)

regulation of axon extension (ISO)

substrate localization to autophagosome (IEA,ISO)

type 2 mitophagy (ISO)

ubiquitin-dependent protein catabolic process (IEA,ISO)

Cellular Component

axon (IDA)

cytoplasm (IBA,IEA,ISO)

cytosol (IEA)

mitochondrion (IEA,ISO)

neuronal cell body (IDA)

plasma membrane (IEA,ISO)

Molecular Function

activin receptor binding (IEA,ISO)

catalytic activity (IEA)

I-SMAD binding (IEA,ISO)

protein binding (IPI,ISO)

R-SMAD binding (IEA,ISO)

SMAD binding (IBA)

transferase activity (IEA)

transforming growth factor beta receptor binding (IEA,ISO)

ubiquitin protein ligase activity (IBA,IEA,ISO)

ubiquitin-protein transferase activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Bone morphogenetic proteins signaling pathway (ISO)

transforming growth factor-beta Smad dependent signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The Nedd4-like family of E3 ubiquitin ligases and cancer.	Chen C and Matesic LE, Cancer Metastasis Rev. 2007 Dec;26(3-4):587-604.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation.	Kannan M, etal., PLoS One. 2012;7(11):e50735. doi: 10.1371/journal.pone.0050735. Epub 2012 Nov 30.
4.	Up-regulation of Smurf1 after spinal cord injury in adult rats.	Li D, etal., J Mol Histol. 2013 Aug;44(4):381-90. doi: 10.1007/s10735-013-9499-2. Epub 2013 Apr 18.
5.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Mechanisms of TGF-beta signaling from cell membrane to the nucleus.	Shi Y and Massague J, Cell. 2003 Jun 13;113(6):685-700.
10.	Protein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarity.	Vohra BP, etal., J Neurosci. 2007 Aug 29;27(35):9458-68.

Additional References at PubMed

PMID:10458166	PMID:11278251	PMID:12151385	PMID:15820682	PMID:19056867	PMID:19937093	PMID:21454619	PMID:21572392	PMID:22020285	PMID:23999003	PMID:25901863	PMID:27214554
PMID:28341855	PMID:28940129	PMID:29016730	PMID:30158054	PMID:31778769	PMID:32871042	PMID:33000773	PMID:35034538	PMID:35126820	PMID:36579844

Genomics

Comparative Map Data

Smurf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	14,748,717 - 14,840,273 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	14,749,043 - 14,840,273 (+)	Ensembl				GRCr8
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	9,635,025 - 9,726,519 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	10,438,588 - 10,530,424 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	11,061,801 - 11,153,638 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	10,086,150 - 10,176,124 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	11,433,815 - 11,526,465 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	11,407,213 - 11,526,465 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	13,499,018 - 13,591,105 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	9,950,304 - 10,042,391 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	11,439,779 - 11,530,606 (+)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

SMURF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	99,027,440 - 99,144,108 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	99,027,435 - 99,144,164 (-)	Ensembl			hg38	GRCh38
GRCh37	7	98,625,063 - 98,741,731 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	98,463,000 - 98,579,659 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	7	93,353,908 - 93,471,364 (-)	NCBI		Celera
Cytogenetic Map	7	q22.1	NCBI
HuRef	7	93,257,804 - 93,374,432 (-)	NCBI		HuRef
CHM1_1	7	98,555,482 - 98,672,053 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	100,260,765 - 100,377,379 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	97,981,091 - 98,097,765 (-)	NCBI

Smurf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	144,813,305 - 144,902,657 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	144,813,305 - 144,902,657 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	144,876,495 - 144,965,899 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	144,876,495 - 144,965,847 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	145,637,364 - 145,726,699 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	145,130,022 - 145,219,357 (-)	NCBI		MGSCv36	mm8
MGSCv36	5	143,961,853 - 144,051,632 (-)	NCBI		MGSCv36	mm8
Celera	5	141,867,627 - 141,904,898 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	84.83	NCBI

Smurf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	14,774,545 - 14,802,879 (-)	Ensembl
ChiLan1.0	NW_004955460	14,774,545 - 14,860,783 (-)	NCBI	ChiLan1.0	ChiLan1.0

SMURF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	116,882,049 - 116,998,395 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	165,146,684 - 165,263,030 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	90,995,923 - 91,112,240 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	104,500,965 - 104,568,046 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	104,500,965 - 104,568,046 (-)	Ensembl			panPan2	panpan1.1

SMURF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	10,385,781 - 10,498,071 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	10,385,779 - 10,494,922 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	12,010,745 - 12,124,123 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	10,384,720 - 10,498,106 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	10,384,957 - 10,497,052 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	10,254,596 - 10,367,952 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	10,233,259 - 10,346,407 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	10,466,893 - 10,580,346 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Smurf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	138,531,835 - 138,563,396 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936750	1,381,851 - 1,407,323 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936750	1,381,864 - 1,406,736 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMURF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	6,037,741 - 6,142,575 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	6,037,732 - 6,142,569 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	6,098,677 - 6,149,341 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SMURF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	14,019,733 - 14,141,588 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	14,019,968 - 14,141,795 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666070	2,154,820 - 2,276,911 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Smurf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	32,483,092 - 32,615,260 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624740	32,480,138 - 32,615,436 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Smurf1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	8,230,555 - 8,321,137 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Smurf1
1475 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	891
Count of miRNA genes:	300
Interacting mature miRNAs:	403
Transcripts:	ENSRNOT00000031901
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1357337	Gluco3	Glucose level QTL 3		0.0004	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	12	1	16966671	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	11869600	16966542	Rat
61334	Gluco17	Glucose level QTL 17	6.3		adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	12	1	16966671	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	12233000	30490641	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
724526	Uae3	Urinary albumin excretion QTL 3	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	12	1	15486827	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

RH142403

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	9,726,080 - 9,726,238 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	11,526,027 - 11,526,184	NCBI	Rnor6.0
Rnor_5.0	12	13,590,667 - 13,590,824	UniSTS	Rnor5.0
RGSC_v3.4	12	10,041,953 - 10,042,110	UniSTS	RGSC3.4
Celera	12	11,530,168 - 11,530,325	UniSTS
RH 3.4 Map	12	144.41	UniSTS
Cytogenetic Map	12	p11	UniSTS

BE096092

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	9,653,529 - 9,653,679 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	11,453,456 - 11,453,605	NCBI	Rnor6.0
Rnor_6.0	12	11,425,771 - 11,425,920	NCBI	Rnor6.0
Rnor_5.0	12	13,518,096 - 13,518,245	UniSTS	Rnor5.0
Rnor_5.0	12	13,490,974 - 13,491,123	UniSTS	Rnor5.0
RGSC_v3.4	12	9,969,383 - 9,969,532	UniSTS	RGSC3.4
Celera	12	11,457,969 - 11,458,118	UniSTS
RH 3.4 Map	12	119.7	UniSTS
Cytogenetic Map	12	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109598	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001443862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010056420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000031901 ⟹ ENSRNOP00000031927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	14,749,043 - 14,840,273 (+)	Ensembl
mRatBN7.2 Ensembl	12	9,635,025 - 9,726,519 (+)	Ensembl
Rnor_6.0 Ensembl	12	11,433,813 - 11,523,820 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082989 ⟹ ENSRNOP00000071653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	14,749,043 - 14,840,273 (+)	Ensembl
mRatBN7.2 Ensembl	12	9,635,309 - 9,726,519 (+)	Ensembl
Rnor_6.0 Ensembl	12	11,407,213 - 11,526,465 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084577 ⟹ ENSRNOP00000073635

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	14,749,043 - 14,840,273 (+)	Ensembl
mRatBN7.2 Ensembl	12	9,635,309 - 9,726,519 (+)	Ensembl
Rnor_6.0 Ensembl	12	11,433,819 - 11,523,771 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112221 ⟹ ENSRNOP00000076358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	14,764,081 - 14,840,273 (+)	Ensembl
mRatBN7.2 Ensembl	12	9,700,949 - 9,726,519 (+)	Ensembl

RefSeq Acc Id:

NM_001109598 ⟹ NP_001103068

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,749,043 - 14,840,273 (+)	NCBI
mRatBN7.2	12	9,635,309 - 9,726,519 (+)	NCBI
Rnor_6.0	12	11,433,815 - 11,526,465 (+)	NCBI
Rnor_5.0	12	13,499,018 - 13,591,105 (+)	NCBI
RGSC_v3.4	12	9,950,304 - 10,042,391 (+)	ENTREZGENE
Celera	12	11,439,779 - 11,530,606 (+)	ENTREZGENE

Sequence:

show sequence

GCCGGCCGGCCGCTGGCGGGAGATGTCGAACCCCGGGACCCGTAGGAACGGCTCCAGCATCAAG
ATCCGTCTGACAGTATTGTGTGCCAAGAACCTTGCAAAGAAAGACTTCTTCAGACTCCCCGACC
CCTTTGCCAAGATTGTTGTGGACGGCTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACAC
CCTGGACCCAAAGTGGAACCAGCACTATGACCTGTACGTTGGGAAAACCGACTCGATAACCATC
AGTGTGTGGAACCACAAGAAGATCCACAAGAAGCAGGGGGCTGGCTTCCTGGGCTGCGTGCGGC
TGCTCTCCAATGCCATCAGCAGATTGAAAGATACCGGCTACCAGCGTTTGGATCTATGCAAACT
AAATCCCTCAGATACTGATGCAGTTCGTGGCCAAATAGTGGTCAGTTTACAGACCCGAGACAGA
ATAGGTGGTGGAGGGTCGGTGGTGGACTGCAGGGGACTGCTGGAGAACGAAGGAACGGTATATG
AAGACTCAGGCCCTGGAAGGCCGCTCAGCTGCCTCATGGAGGAACCTGCCCCGTATACAGATGG
CACCGGTGCAGCGGCAGGAGGTGGGAACTGCAGGTTTGTGGAGTCTCCAAGCCAAGATCAGAGA
CTCCTGGTACAGCGACTCCGAAATCCTGAGGTTCGAGGATCCCTACAGACACCGCAGAATCGAC
CACATGGCCACCAGTCACCGGAGCTGCCTGAAGGCTACGAGCAAAGGACAACAGTGCAGGGACA
AGTTTACTTTTTGCACACGCAGACTGGAGTCAGCACATGGCACGACCCCAGGATCCCCAGAGAC
CTTAACAGTGTGAACTGCGATGAACTTGGGCCACTGCCTCCAGGCTGGGAAGTCAGAAGCACAG
TGTCGGGAAGAATCTATTTTGTAGATCACAATAATAGGACAACCCAGTTTACAGACCCACGGCT
TCACCACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAGCCAGCCGCTGCAGTTGCCCAGT
GAGGGCTCCGTGGAGGACGAGGAGCTTCCTGCCCAGAGATATGAGAGAGATTTAGTCCAGAAGC
TTAAAGTTCTCAGACATGAGCTCTCTCTTCAGCAGCCCCAAGCTGGTCATTGTCGCATAGAAGT
TTCCAGAGAAGAAATATTTGAGGAGTCATATCGCCAGATCATGAAGATGCGACCAAAAGACCTG
AAGAAGCGCCTGATGGTGAAGTTCCGAGGGGAGGAAGGCTTGGACTATGGTGGGGTGGCTCGGG
AGTGGCTGTATTTGTTGTGCCATGAAATGTTGAATCCGTATTATGGACTCTTCCAGTATTCCAC
GGACAATATTTACACACTGCAAATCAACCCAGATTCTTCTATCAACCCTGACCATCTGTCTTAC
TTCCACTTTGTGGGTCGCATCATGGGTCTGGCTGTGTTCCATGGACACTACATAAACGGGGGCT
TCACAGTTCCTTTCTACAAGCAGCTCCTGGGAAAACCCATCCAGCTGTCGGATCTGGAGTCAGT
GGACCCAGAACTTCACAAGAGCTTGGTGTGGATTCTAGAGAATGACATCACGCCAGTGCTGGAT
CACACCTTCTGCGTGGAGCACAATGCTTTTGGGCGGATCCTTCAGCATGAACTGAAACCCAATG
GCAGAAATGTGCCTGTCACTGAGGAGAACAAGAAGGAGTATGTGCGGTTGTATGTGAACTGGAG
GTTTATGAGAGGAATCGAAGCCCAGTTCCTAGCGCTTCAGAAAGGGTTTAACGAACTCATTCCC
CAACACTTACTGAAGCCCTTTGACCAGAAGGAACTAGAGCTGATAATAGGCGGCCTGGATAAGA
TAGACCTGAATGACTGGAAGTCCAACACTCGGCTGAAGCACTGTGTGGCAGACAGCAACATCGT
CAGGTGGTTCTGGCAGGCGGTGGAGACCTTCGATGAGGAGAGGAGAGCCAGGCTCCTGCAGTTT
GTGACAGGATCCACACGAGTTCCTCTCCAAGGCTTCAAGGCTCTGCAAGGCGCGGCAGGGCCCC
GGCTCTTCACCATCCACCTGATTGACGCCAACACCGACAACCTGCCCAAGGCCCACACCTGCTT
TAATCGGATTGACATCCCACCCTATGAGTCCTATGAGAAGCTCTATGAGAAGCTGCTGACAGCG
GTAGAGGAGACCTGTGGCTTTGCCGTGGAGTGAAGAGCAGCCCGTGGCCACAGAGTCTTGCTCA
CAACCACCAGACCCAAAGCATATGGCGTCTGCGCGCCTCCCGCATGGCGGGCGGAGGCCTGAGA
TTCCAGAAACCGAGGGAAAAGGCTCGTCTCCCTCCTCCTTTGGAGAAGGCAGGCCAGGGGACTT
TCATAGGTGGCTCCCACCCATTTATTCCTCCTTTATTATAGTTCGCCCACTCCTCCATCACCCA
TCCAATAAAACGCAGCCAGGTTTCGCCCTCAGCCTCCTTGGCATGGTGGTAAGGCTGTGGTGTC
TCCGGGAGCATCAACCATGGTCAGGGCCAAGCTGGGCCCCGAGGGTTTGCGTGGCCTCTGTACC
AGCTCCCCCTCTAACTGTAGCCGCAAAGCCCCCTTTCAAGTTCAGCAGCTGCCAATAGCTTACT
GATCTCAAATTCCAGAGGCCTCACAGGCTTGCAGCCTGTCCAGATAGCCGGTGGATCTCCAAGC
AGGAGGTAAAGGCAGTGAATGCTTGCTGGAACTCCACTATGGTAGGAGACTCGAGGCGATGTGT
TTTCCCCTTTGAGAGGTAAAGGAATTGCAACAGCCTTCACTGGAAGCCTGGGTACTTTTCACAG
TGTCCTGGCTAAAAATAAGGTTTTGCAGGGGAAAAAAATCTTTAAAAGTACAATTTGCTGTGTT
CCCTACCCAGTTTGAAATTATCACGTCATGGAGCTAAGCAAAGAATAACCAAAACCAGCCTCTG
ACCCCTGGGTCCAGCTCAGTTTCTGTGCCTGGGGATCCAGAGGCTCCTAGCTGTCTTGAAATGG
ACTCACATATGGGGATTGCTAAGAGCTAAACTAACAGAACAATTTTGTCACCGCAGCCATTGGG
TGGAACAGCAGGAGAGGCCGCTGACCTGGGGTCCCCTGATGTAGCTCCCCAGGGTTGGTGCTGT
GCACAGAGCAGGGTGTGGTGGGGCGCGTGGCAACAGGGTGGGGGCTTTACCTCCCTACGTGGCC
CTCTTCCCCATGGCAGCGGTGATGCTAACAGTTCTACTCAGTTTGCTTGCTCAGTCTCCGAGCA
AGGCCAAAGCCAGCCTAACACGTCTAACAGCACTTCCGGTCGCACACGGCTTCACAGACGTTGA
CTCTTACAGCCGAGCAGCTGGACTGAGACAGCTGAGCTCTGGTGGAAGGCAGGGCAGCAGCCAG
GTTTCCATTTGTAGTTTTGTTGTTTTTGTTTGTGGTGGGGGTGAGAACAGGGTAATTCATTAGC
AAGACATTTCATTGGTACCAGGGCTCAGGTTCAGCCACGAGTTCAAGTTGTATGGCAGATGATC
AGGAAGGTCCTGTTGGGACACTGGCTTTTGTGGTTTTTCTGTTGCTTCCCCTCAGGCTGAGGGT
AGGGAAGTGTCTGCTGCTTCTGTCCAGTGTGGTCTGAAGCAGTGCTGAGGTGATAGGGGGAGTG
GATTCATAGGGCACATACACCCCCTAACCGAAGAGATTTGTCCAGCTTGGCCACTGGCACTACA
GAGCATGAGTCAGCTGCACTCTGGGTTGCCAGGGTGAGGATGCTAGGTAGACCTCACTGCACAA
GGACCGAACCCACCCCACCTCCCAGGCCAGACTGGGGCCTTATTAGTCTCTCAATTCTGCCTTG
CCCCAGTAGGGCTTCTGTAATTCATCTACCTTCAAGCTTCTGAGGGTGTTCTAAAACCCAGCTC
CCTCATGACTCGTGGATTCAAAAGGCGCAAGGAAGCCTGTGTCCTAAGTCTCAGCCAGTCCATA
GGAAGCAACCAGACCCCACACAGTGACACACTTTCTGGAGACCAGAAACCTTGCCTGTTGCCCT
GGCACCGTCCAGACTGCAGTGATGAAGGACACCAGGGTTCTGTGCTTCGGGGATGTGTGCAGGA
GTGTCAGGTCATACTGTTTGTGCCTCGGGAGTGATGGGGGACAAGCCTTAGGAGTCCCGTGTCA
GATGCCCTCAGAGGAAGATCCAGAGGCTGGGCCTTTAGGGGCCGACTGGCTGGCACACATGCCA
CCTACTAAGGCTTCTAACAGTCACTGTGCCTGCATTGCTCGTGGGTTCCCCTCATTGCCGGTTC
TGAGTGTCACAACCTCCCCCAGGTCTGTTCATGCATAGCACTGTCGTCTGTTGGTAGCGCTGCA
CTTCCTTGTCTGTCTACCATGGTTAGGCCCTTCTGACGCTCCTCAAAGACACTGCGTGGCCGGC
CCACGGCACAGCTCCTGGTTGCCCTGCTTGGGTCTGGGTGAAGCCCTTTCATGTCAGACCTCGG
TCGTCCTAGTGGCCACCATCACCCAGATGCTTCAGGAGTCCTGCTCTCCAGGCTCCCCTCACCA
GCGGCCGGCAGCCACACTCAGGGACGCAGCAAACACCACTCTGCTCGGCAGTGCTTCAGAGAGG
ACACCAGGCTGCCGCAATGGTGTGGCAGCAGGTCGCCGTCTCCTGCTGTCTGTGAGGAGACTCT
GCCACAAGATGAGACGCTAACCCCTGGCCTGGCTTGGCCACAAGGTCAGGTTCAGGTCGGGCGA
ACGCTGGACCGATCTGCAGAGAACACGCCTCATCCTACCGCAGCCTGGGGGCCACGTGGCAGCC
TTCTGAAACAGTGTGGATTTTTAAACTGTGTTTATAATGTATTCTTATTTATTTTGTAAGGTCC
TGTTTGAAGTGCTGCTGCTACCCCTAGTTGCTCCCCCAGTTTTTATTGCCCATTAACCTGTGAC
AGTTGTACACTAATGTTCTATGTCAGAATGGAAAGTATTTAAAGAAATGCTAGTTCTATTTAAT
GCAGTCGTGGAACCAGCTGGAAACACAAAACGTTGACTGTACAGCAGGCTGGACCCGGGAGGTC
AGGTTCATTTTGTTACATATGCAATAAACTCACAACTTTACTTTT

hide sequence

RefSeq Acc Id:

XM_006248882 ⟹ XP_006248944

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,748,717 - 14,840,273 (+)	NCBI
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI
Rnor_6.0	12	11,433,819 - 11,526,465 (+)	NCBI
Rnor_5.0	12	13,499,018 - 13,591,105 (+)	NCBI

Sequence:

show sequence

GCCGGCCGCTGGCGGGAGATGTCGAACCCCGGGACCCGTAGGAACGGCTCCAGCATCAAGATCC
GTCTGACAGTATTGTGTGCCAAGAACCTTGCAAAGAAAGACTTCTTCAGACTCCCCGACCCCTT
TGCCAAGATTGTTGTGGACGGCTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACACCCTG
GACCCAAAGTGGAACCAGCACTATGACCTGTACGTTGGGAAAACCGACTCGATAACCATCAGTG
TGTGGAACCACAAGAAGATCCACAAGAAGCAGGGGGCTGGCTTCCTGGGCTGCGTGCGGCTGCT
CTCCAATGCCATCAGCAGATTGAAAGATACCGGCTACCAGCGTTTGGATCTATGCAAACTAAAT
CCCTCAGATACTGATGCAGTTCGTGGCCAAATAGTGGTCAGTTTACAGACCCGAGACAGAATAG
GTGGTGGAGGGTCGGTGGTGGACTGCAGGGGACTGCTGGAGAACGAAGGAACGGTATATGAAGA
CTCAGGCCCTGGAAGGCCGCTCAGCTGCCTCATGGAGGAACCTGCCCCGTATACAGATGGCACC
GGTGCAGCGGCAGGAGGTGGGAACTGCAGGTTTGTGGAGTCTCCAAGCCAAGATCAGAGACTCC
TGGTACAGCGACTCCGAAATCCTGAGGTTCGAGGATCCCTACAGACACCGCAGAATCGACCACA
TGGCCACCAGTCACCGGAGCTGCCTGAAGGCTACGAGCAAAGGACAACAGTGCAGGGACAAGTT
TACTTTTTGCACACGCAGACTGGAGTCAGCACATGGCACGACCCCAGGATCCCCAGTCCCTTGG
GGACCATTCCGGGGGGAGATGAAGCTTTTCTATACGAATTCCTTCTACAAGGCCATACATCCGA
GCCCAGAGACCTTAACAGTGTGAACTGCGATGAACTTGGGCCACTGCCTCCAGGCTGGGAAGTC
AGAAGCACAGTGTCGGGAAGAATCTATTTTGTAGATCACAATAATAGGACAACCCAGTTTACAG
ACCCACGGCTTCACCACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAGCCAGCCGCTGCA
GTTGCCCAGTGAGGGCTCCGTGGAGGACGAGGAGCTTCCTGCCCAGAGATATGAGAGAGATTTA
GTCCAGAAGCTTAAAGTTCTCAGACATGAGCTCTCTCTTCAGCAGCCCCAAGCTGGTCATTGTC
GCATAGAAGTTTCCAGAGAAGAAATATTTGAGGAGTCATATCGCCAGATCATGAAGATGCGACC
AAAAGACCTGAAGAAGCGCCTGATGGTGAAGTTCCGAGGGGAGGAAGGCTTGGACTATGGTGGG
GTGGCTCGGGAGTGGCTGTATTTGTTGTGCCATGAAATGTTGAATCCGTATTATGGACTCTTCC
AGTATTCCACGGACAATATTTACACACTGCAAATCAACCCAGATTCTTCTATCAACCCTGACCA
TCTGTCTTACTTCCACTTTGTGGGTCGCATCATGGGTCTGGCTGTGTTCCATGGACACTACATA
AACGGGGGCTTCACAGTTCCTTTCTACAAGCAGCTCCTGGGAAAACCCATCCAGCTGTCGGATC
TGGAGTCAGTGGACCCAGAACTTCACAAGAGCTTGGTGTGGATTCTAGAGAATGACATCACGCC
AGTGCTGGATCACACCTTCTGCGTGGAGCACAATGCTTTTGGGCGGATCCTTCAGCATGAACTG
AAACCCAATGGCAGAAATGTGCCTGTCACTGAGGAGAACAAGAAGGAGTATGTGCGGTTGTATG
TGAACTGGAGGTTTATGAGAGGAATCGAAGCCCAGTTCCTAGCGCTTCAGAAAGGGTTTAACGA
ACTCATTCCCCAACACTTACTGAAGCCCTTTGACCAGAAGGAACTAGAGCTGATAATAGGCGGC
CTGGATAAGATAGACCTGAATGACTGGAAGTCCAACACTCGGCTGAAGCACTGTGTGGCAGACA
GCAACATCGTCAGGTGGTTCTGGCAGGCGGTGGAGACCTTCGATGAGGAGAGGAGAGCCAGGCT
CCTGCAGTTTGTGACAGGATCCACACGAGTTCCTCTCCAAGGCTTCAAGGCTCTGCAAGGCTCT
ACAGGCGCGGCAGGGCCCCGGCTCTTCACCATCCACCTGATTGACGCCAACACCGACAACCTGC
CCAAGGCCCACACCTGCTTTAATCGGATTGACATCCCACCCTATGAGTCCTATGAGAAGCTCTA
TGAGAAGCTGCTGACAGCGGTAGAGGAGACCTGTGGCTTTGCCGTGGAGTGAAGAGCAGCCCGT
GGCCACAGAGTCTTGCTCACAACCACCAGACCCAAAGCATATGGCGTCTGCGCGCCTCCCGCAT
GGCGGGCGGAGGCCTGAGATTCCAGAAACCGAGGGAAAAGGCTCGTCTCCCTCCTCCTTTGGAG
AAGGCAGGCCAGGGGACTTTCATAGGTGGCTCCCACCCATTTATTCCTCCTTTATTATAGTTCG
CCCACTCCTCCATCACCCATCCAATAAAACGCAGCCAGGTTTCGCCCTCAGCCTCCTTGGCATG
GTGGTAAGGCTGTGGTGTCTCCGGGAGCATCAACCATGGTCAGGGCCAAGCTGGGCCCCGAGGG
TTTGCGTGGCCTCTGTACCAGCTCCCCCTCTAACTGTAGCCGCAAAGCCCCCTTTCAAGTTCAG
CAGCTGCCAATAGCTTACTGATCTCAAATTCCAGAGGCCTCACAGGCTTGCAGCCTGTCCAGAT
AGCCGGTGGATCTCCAAGCAGGAGGTAAAGGCAGTGAATGCTTGCTGGAACTCCACTATGGTAG
GAGACTCGAGGCGATGTGTTTTCCCCTTTGAGAGGTAAAGGAATTGCAACAGCCTTCACTGGAA
GCCTGGGTACTTTTCACAGTGTCCTGGCTAAAAATAAGGTTTTGCAGGGGAAAAAAATCTTTAA
AAGTACAATTTGCTGTGTTCCCTACCCAGTTTGAAATTATCACGTCATGGAGCTAAGCAAAGAA
TAACCAAAACCAGCCTCTGACCCCTGGGTCCAGCTCAGTTTCTGTGCCTGGGGATCCAGAGGCT
CCTAGCTGTCTTGAAATGGACTCACATATGGGGATTGCTAAGAGCTAAACTAACAGAACAATTT
TGTCACCGCAGCCATTGGGTGGAACAGCAGGAGAGGCCGCTGACCTGGGGTCCCCTGATGTAGC
TCCCCAGGGTTGGTGCTGTGCACAGAGCAGGGTGTGGTGGGGCGCGTGGCAACAGGGTGGGGGC
TTTACCTCCCTACGTGGCCCTCTTCCCCATGGCAGCGGTGATGCTAACAGTTCTACTCAGTTTG
CTTGCTCAGTCTCCGAGCAAGGCCAAAGCCAGCCTAACACGTCTAACAGCACTTCCGGTCGCAC
ACGGCTTCACAGACGTTGACTCTTACAGCCGAGCAGCTGGACTGAGACAGCTGAGCTCTGGTGG
AAGGCAGGGCAGCAGCCAGGTTTCCATTTGTAGTTTTGTTGTTTTTGTTTGTGGTGGGGGTGAG
AACAGGGTAATTCATTAGCAAGACATTTCATTGGTACCAGGGCTCAGGTTCAGCCACGAGTTCA
AGTTGTATGGCAGATGATCAGGAAGGTCCTGTTGGGACACTGGCTTTTGTGGTTTTTCTGTTGC
TTCCCCTCAGGCTGAGGGTAGGGAAGTGTCTGCTGCTTCTGTCCAGTGTGGTCTGAAGCAGTGC
TGAGGTGATAGGGGGAGTGGATTCATAGGGCACATACACCCCCTAACCGAAGAGATTTGTCCAG
CTTGGCCACTGGCACTACAGAGCATGAGTCAGCTGCACTCTGGGTTGCCAGGGTGAGGATGCTA
GGTAGACCTCACTGCACAAGGACCGAACCCACCCCACCTCCCAGGCCAGACTGGGGCCTTATTA
GTCTCTCAATTCTGCCTTGCCCCAGTAGGGCTTCTGTAATTCATCTACCTTCAAGCTTCTGAGG
GTGTTCTAAAACCCAGCTCCCTCATGACTCGTGGATTCAAAAGGCGCAAGGAAGCCTGTGTCCT
AAGTCTCAGCCAGTCCATAGGAAGCAACCAGACCCCACACAGTGACACACTTTCTGGAGACCAG
AAACCTTGCCTGTTGCCCTGGCACCGTCCAGACTGCAGTGATGAAGGACACCAGGGTTCTGTGC
TTCGGGGATGTGTGCAGGAGTGTCAGGTCATACTGTTTGTGCCTCGGGAGTGATGGGGGACAAG
CCTTAGGAGTCCCGTGTCAGATGCCCTCAGAGGAAGATCCAGAGGCTGGGCCTTTAGGGGCCGA
CTGGCTGGCACACATGCCACCTACTAAGGCTTCTAACAGTCACTGTGCCTGCATTGCTCGTGGG
TTCCCCTCATTGCCGGTTCTGAGTGTCACAACCTCCCCCAGGTCTGTTCATGCATAGCACTGTC
GTCTGTTGGTAGCGCTGCACTTCCTTGTCTGTCTACCATGGTTAGGCCCTTCTGACGCTCCTCA
AAGACACTGCGTGGCCGGCCCACGGCACAGCTCCTGGTTGCCCTGCTTGGGTCTGGGTGAAGCC
CTTTCATGTCAGACCTCGGTCGTCCTAGTGGCCACCATCACCCAGATGCTTCAGGAGTCCTGCT
CTCCAGGCTCCCCTCACCAGCGGCCGGCAGCCACACTCAGGGACGCAGCAAACACCACTCTGCT
CGGCAGTGCTTCAGAGAGGACACCAGGCTGCCGCAATGGTGTGGCAGCAGGTCGCCGTCTCCTG
CTGTCTGTGAGGAGACTCTGCCACAAGATGAGACGCTAACCCCTGGCCTGGCTTGGCCACAAGG
TCAGGTTCAGGTCGGGCGAACGCTGGACCGATCTGCAGAGAACACGCCTCATCCTACCGCAGCC
TGGGGGCCACGTGGCAGCCTTCTGAAACAGTGTGGATTTTTAAACTGTGTTTATAATGTATTCT
TATTTATTTTGTAAGGTCCTGTTTGAAGTGCTGCTGCTACCCCTAGTTGCTCCCCCAGTTTTTA
TTGCCCATTAACCTGTGACAGTTGTACACTAATGTTCTATGTCAGAATGGAAAGTATTTAAAGA
AATGCTAGTTCTATTTAATGCAGTCGTGGAACCAGCTGGAAACACAAAACGTTGACTGTACAGC
AGGCTGGACCCGGGAGGTCAGGTTCATTTTGTTACATATGCAATAAACTCACAACTTTACTTTT

hide sequence

RefSeq Acc Id:

XM_008769002 ⟹ XP_008767224

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,748,751 - 14,840,273 (+)	NCBI
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI
Rnor_6.0	12	11,433,819 - 11,526,465 (+)	NCBI

Sequence:

show sequence

GCCGGCCGCTGGCGGGAGATGTCGAACCCCGGGACCCGTAGGAACGGCTCCAGCATCAAGATCC
GTCTGACAGTATTGTGTGCCAAGAACCTTGCAAAGAAAGACTTCTTCAGACTCCCCGACCCCTT
TGCCAAGATTGTTGTGGACGGCTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACACCCTG
GACCCAAAGTGGAACCAGCACTATGACCTGTACGTTGGGAAAACCGACTCGATAACCATCAGTG
TGTGGAACCACAAGAAGATCCACAAGAAGCAGGGGGCTGGCTTCCTGGGCTGCGTGCGGCTGCT
CTCCAATGCCATCAGCAGATTGAAAGATACCGGCTACCAGCGTTTGGATCTATGCAAACTAAAT
CCCTCAGATACTGATGCAGTTCGTGGCCAAATAGTGGTCAGTTTACAGACCCGAGACAGAATAG
GTGGTGGAGGGTCGGTGGTGGACTGCAGGGGACTGCTGGAGAACGAAGGAACGGTATATGAAGA
CTCAGGCCCTGGAAGGCCGCTCAGCTGCCTCATGGAGGAACCTGCCCCGTATACAGATGGCACC
GGTGCAGCGGCAGGAGGTGGGAACTGCAGGTTTGTGGAGTCTCCAAGCCAAGATCAGAGACTCC
TGGTACAGCGACTCCGAAATCCTGAGGTTCGAGGATCCCTACAGACACCGCAGAATCGACCACA
TGGCCACCAGTCACCGGAGCTGCCTGAAGGCTACGAGCAAAGGACAACAGTGCAGGGACAAGTT
TACTTTTTGCACACGCAGACTGGAGTCAGCACATGGCACGACCCCAGGATCCCCAGAGACCTTA
ACAGTGTGAACTGCGATGAACTTGGGCCACTGCCTCCAGGCTGGGAAGTCAGAAGCACAGTGTC
GGGAAGAATCTATTTTGTAGATCACAATAATAGGACAACCCAGTTTACAGACCCACGGCTTCAC
CACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAGCCAGCCGCTGCAGTTGCCCAGTGAGG
GCTCCGTGGAGGACGAGGAGCTTCCTGCCCAGAGATATGAGAGAGATTTAGTCCAGAAGCTTAA
AGTTCTCAGACATGAGCTCTCTCTTCAGCAGCCCCAAGCTGGTCATTGTCGCATAGAAGTTTCC
AGAGAAGAAATATTTGAGGAGTCATATCGCCAGATCATGAAGATGCGACCAAAAGACCTGAAGA
AGCGCCTGATGGTGAAGTTCCGAGGGGAGGAAGGCTTGGACTATGGTGGGGTGGCTCGGGAGTG
GCTGTATTTGTTGTGCCATGAAATGTTGAATCCGTATTATGGACTCTTCCAGTATTCCACGGAC
AATATTTACACACTGCAAATCAACCCAGATTCTTCTATCAACCCTGACCATCTGTCTTACTTCC
ACTTTGTGGGTCGCATCATGGGTCTGGCTGTGTTCCATGGACACTACATAAACGGGGGCTTCAC
AGTTCCTTTCTACAAGCAGCTCCTGGGAAAACCCATCCAGCTGTCGGATCTGGAGTCAGTGGAC
CCAGAACTTCACAAGAGCTTGGTGTGGATTCTAGAGAATGACATCACGCCAGTGCTGGATCACA
CCTTCTGCGTGGAGCACAATGCTTTTGGGCGGATCCTTCAGCATGAACTGAAACCCAATGGCAG
AAATGTGCCTGTCACTGAGGAGAACAAGAAGGAGTATGTGCGGTTGTATGTGAACTGGAGGTTT
ATGAGAGGAATCGAAGCCCAGTTCCTAGCGCTTCAGAAAGGGTTTAACGAACTCATTCCCCAAC
ACTTACTGAAGCCCTTTGACCAGAAGGAACTAGAGCTGATAATAGGCGGCCTGGATAAGATAGA
CCTGAATGACTGGAAGTCCAACACTCGGCTGAAGCACTGTGTGGCAGACAGCAACATCGTCAGG
TGGTTCTGGCAGGCGGTGGAGACCTTCGATGAGGAGAGGAGAGCCAGGCTCCTGCAGTTTGTGA
CAGGATCCACACGAGTTCCTCTCCAAGGCTTCAAGGCTCTGCAAGGCTCTACAGGCGCGGCAGG
GCCCCGGCTCTTCACCATCCACCTGATTGACGCCAACACCGACAACCTGCCCAAGGCCCACACC
TGCTTTAATCGGATTGACATCCCACCCTATGAGTCCTATGAGAAGCTCTATGAGAAGCTGCTGA
CAGCGGTAGAGGAGACCTGTGGCTTTGCCGTGGAGTGAAGAGCAGCCCGTGGCCACAGAGTCTT
GCTCACAACCACCAGACCCAAAGCATATGGCGTCTGCGCGCCTCCCGCATGGCGGGCGGAGGCC
TGAGATTCCAGAAACCGAGGGAAAAGGCTCGTCTCCCTCCTCCTTTGGAGAAGGCAGGCCAGGG
GACTTTCATAGGTGGCTCCCACCCATTTATTCCTCCTTTATTATAGTTCGCCCACTCCTCCATC
ACCCATCCAATAAAACGCAGCCAGGTTTCGCCCTCAGCCTCCTTGGCATGGTGGTAAGGCTGTG
GTGTCTCCGGGAGCATCAACCATGGTCAGGGCCAAGCTGGGCCCCGAGGGTTTGCGTGGCCTCT
GTACCAGCTCCCCCTCTAACTGTAGCCGCAAAGCCCCCTTTCAAGTTCAGCAGCTGCCAATAGC
TTACTGATCTCAAATTCCAGAGGCCTCACAGGCTTGCAGCCTGTCCAGATAGCCGGTGGATCTC
CAAGCAGGAGGTAAAGGCAGTGAATGCTTGCTGGAACTCCACTATGGTAGGAGACTCGAGGCGA
TGTGTTTTCCCCTTTGAGAGGTAAAGGAATTGCAACAGCCTTCACTGGAAGCCTGGGTACTTTT
CACAGTGTCCTGGCTAAAAATAAGGTTTTGCAGGGGAAAAAAATCTTTAAAAGTACAATTTGCT
GTGTTCCCTACCCAGTTTGAAATTATCACGTCATGGAGCTAAGCAAAGAATAACCAAAACCAGC
CTCTGACCCCTGGGTCCAGCTCAGTTTCTGTGCCTGGGGATCCAGAGGCTCCTAGCTGTCTTGA
AATGGACTCACATATGGGGATTGCTAAGAGCTAAACTAACAGAACAATTTTGTCACCGCAGCCA
TTGGGTGGAACAGCAGGAGAGGCCGCTGACCTGGGGTCCCCTGATGTAGCTCCCCAGGGTTGGT
GCTGTGCACAGAGCAGGGTGTGGTGGGGCGCGTGGCAACAGGGTGGGGGCTTTACCTCCCTACG
TGGCCCTCTTCCCCATGGCAGCGGTGATGCTAACAGTTCTACTCAGTTTGCTTGCTCAGTCTCC
GAGCAAGGCCAAAGCCAGCCTAACACGTCTAACAGCACTTCCGGTCGCACACGGCTTCACAGAC
GTTGACTCTTACAGCCGAGCAGCTGGACTGAGACAGCTGAGCTCTGGTGGAAGGCAGGGCAGCA
GCCAGGTTTCCATTTGTAGTTTTGTTGTTTTTGTTTGTGGTGGGGGTGAGAACAGGGTAATTCA
TTAGCAAGACATTTCATTGGTACCAGGGCTCAGGTTCAGCCACGAGTTCAAGTTGTATGGCAGA
TGATCAGGAAGGTCCTGTTGGGACACTGGCTTTTGTGGTTTTTCTGTTGCTTCCCCTCAGGCTG
AGGGTAGGGAAGTGTCTGCTGCTTCTGTCCAGTGTGGTCTGAAGCAGTGCTGAGGTGATAGGGG
GAGTGGATTCATAGGGCACATACACCCCCTAACCGAAGAGATTTGTCCAGCTTGGCCACTGGCA
CTACAGAGCATGAGTCAGCTGCACTCTGGGTTGCCAGGGTGAGGATGCTAGGTAGACCTCACTG
CACAAGGACCGAACCCACCCCACCTCCCAGGCCAGACTGGGGCCTTATTAGTCTCTCAATTCTG
CCTTGCCCCAGTAGGGCTTCTGTAATTCATCTACCTTCAAGCTTCTGAGGGTGTTCTAAAACCC
AGCTCCCTCATGACTCGTGGATTCAAAAGGCGCAAGGAAGCCTGTGTCCTAAGTCTCAGCCAGT
CCATAGGAAGCAACCAGACCCCACACAGTGACACACTTTCTGGAGACCAGAAACCTTGCCTGTT
GCCCTGGCACCGTCCAGACTGCAGTGATGAAGGACACCAGGGTTCTGTGCTTCGGGGATGTGTG
CAGGAGTGTCAGGTCATACTGTTTGTGCCTCGGGAGTGATGGGGGACAAGCCTTAGGAGTCCCG
TGTCAGATGCCCTCAGAGGAAGATCCAGAGGCTGGGCCTTTAGGGGCCGACTGGCTGGCACACA
TGCCACCTACTAAGGCTTCTAACAGTCACTGTGCCTGCATTGCTCGTGGGTTCCCCTCATTGCC
GGTTCTGAGTGTCACAACCTCCCCCAGGTCTGTTCATGCATAGCACTGTCGTCTGTTGGTAGCG
CTGCACTTCCTTGTCTGTCTACCATGGTTAGGCCCTTCTGACGCTCCTCAAAGACACTGCGTGG
CCGGCCCACGGCACAGCTCCTGGTTGCCCTGCTTGGGTCTGGGTGAAGCCCTTTCATGTCAGAC
CTCGGTCGTCCTAGTGGCCACCATCACCCAGATGCTTCAGGAGTCCTGCTCTCCAGGCTCCCCT
CACCAGCGGCCGGCAGCCACACTCAGGGACGCAGCAAACACCACTCTGCTCGGCAGTGCTTCAG
AGAGGACACCAGGCTGCCGCAATGGTGTGGCAGCAGGTCGCCGTCTCCTGCTGTCTGTGAGGAG
ACTCTGCCACAAGATGAGACGCTAACCCCTGGCCTGGCTTGGCCACAAGGTCAGGTTCAGGTCG
GGCGAACGCTGGACCGATCTGCAGAGAACACGCCTCATCCTACCGCAGCCTGGGGGCCACGTGG
CAGCCTTCTGAAACAGTGTGGATTTTTAAACTGTGTTTATAATGTATTCTTATTTATTTTGTAA
GGTCCTGTTTGAAGTGCTGCTGCTACCCCTAGTTGCTCCCCCAGTTTTTATTGCCCATTAACCT
GTGACAGTTGTACACTAATGTTCTATGTCAGAATGGAAAGTATTTAAAGAAATGCTAGTTCTAT
TTAATGCAGTCGTGGAACCAGCTGGAAACACAAAACGTTGACTGTACAGCAGGCTGGACCCGGG
AGGTCAGGTTCATTTTGTTACATATGCAATAAACTCACAACTTTACTTTT

hide sequence

RefSeq Acc Id:

XM_017598462 ⟹ XP_017453951

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,748,748 - 14,840,273 (+)	NCBI
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI
Rnor_6.0	12	11,433,819 - 11,526,465 (+)	NCBI

Sequence:

show sequence

GCCGGCCGCTGGCGGGAGATGTCGAACCCCGGGACCCGTAGGAACGGCTCCAGCATCAAGATCC
GTCTGACAGTATTGTGTGCCAAGAACCTTGCAAAGAAAGACTTCTTCAGACTCCCCGACCCCTT
TGCCAAGATTGTTGTGGACGGCTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACACCCTG
GACCCAAAGTGGAACCAGCACTATGACCTGTACGTTGGGAAAACCGACTCGATAACCATCAGTG
TGTGGAACCACAAGAAGATCCACAAGAAGCAGGGGGCTGGCTTCCTGGGCTGCGTGCGGCTGCT
CTCCAATGCCATCAGCAGATTGAAAGATACCGGCTACCAGCGTTTGGATCTATGCAAACTAAAT
CCCTCAGATACTGATGCAGTTCGTGGCCAAATAGTGGTCAGTTTACAGACCCGAGACAGAATAG
GTGGTGGAGGGTCGGTGGTGGACTGCAGGGGACTGCTGGAGAACGAAGGAACGGTATATGAAGA
CTCAGGCCCTGGAAGGCCGCTCAGCTGCCTCATGGAGGAACCTGCCCCGTATACAGATGGCACC
GGTGCAGCGGCAGGAGGTGGGAACTGCAGGTTTGTGGAGTCTCCAAGCCAAGATCAGAGACTCC
TGGTACAGCGACTCCGAAATCCTGAGGTTCGAGGATCCCTACAGACACCGCAGAATCGACCACA
TGGCCACCAGTCACCGGAGCTGCCTGAAGGCTACGAGCAAAGGACAACAGTGCAGGGACAAGTT
TACTTTTTGCACACGCAGACTGGAGTCAGCACATGGCACGACCCCAGGATCCCCAGTCCCTTGG
GGACCATTCCGGGGGGAGATGAAGCTTTTCTATACGAATTCCTTCTACAAGGCCATACATCCGA
GCCCAGAGACCTTAACAGTGTGAACTGCGATGAACTTGGGCCACTGCCTCCAGGCTGGGAAGTC
AGAAGCACAGTGTCGGGAAGAATCTATTTTGTAGATCACAATAATAGGACAACCCAGTTTACAG
ACCCACGGCTTCACCACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAGCCAGCCGCTGCA
GTTGCCCAGTGAGGGCTCCGTGGAGGACGAGGAGCTTCCTGCCCAGAGATATGAGAGAGATTTA
GTCCAGAAGCTTAAAGTTCTCAGACATGAGCTCTCTCTTCAGCAGCCCCAAGCTGGTCATTGTC
GCATAGAAGTTTCCAGAGAAGAAATATTTGAGGAGTCATATCGCCAGATCATGAAGATGCGACC
AAAAGACCTGAAGAAGCGCCTGATGGTGAAGTTCCGAGGGGAGGAAGGCTTGGACTATGGTGGG
GTGGCTCGGGAGTGGCTGTATTTGTTGTGCCATGAAATGTTGAATCCGTATTATGGACTCTTCC
AGTATTCCACGGACAATATTTACACACTGCAAATCAACCCAGATTCTTCTATCAACCCTGACCA
TCTGTCTTACTTCCACTTTGTGGGTCGCATCATGGGTCTGGCTGTGTTCCATGGACACTACATA
AACGGGGGCTTCACAGTTCCTTTCTACAAGCAGCTCCTGGGAAAACCCATCCAGCTGTCGGATC
TGGAGTCAGTGGACCCAGAACTTCACAAGAGCTTGGTGTGGATTCTAGAGAATGACATCACGCC
AGTGCTGGATCACACCTTCTGCGTGGAGCACAATGCTTTTGGGCGGATCCTTCAGCATGAACTG
AAACCCAATGGCAGAAATGTGCCTGTCACTGAGGAGAACAAGAAGGAGTATGTGCGGTTGTATG
TGAACTGGAGGTTTATGAGAGGAATCGAAGCCCAGTTCCTAGCGCTTCAGAAAGGGTTTAACGA
ACTCATTCCCCAACACTTACTGAAGCCCTTTGACCAGAAGGAACTAGAGCTGATAATAGGCGGC
CTGGATAAGATAGACCTGAATGACTGGAAGTCCAACACTCGGCTGAAGCACTGTGTGGCAGACA
GCAACATCGTCAGGTGGTTCTGGCAGGCGGTGGAGACCTTCGATGAGGAGAGGAGAGCCAGGCT
CCTGCAGTTTGTGACAGGATCCACACGAGTTCCTCTCCAAGGCTTCAAGGCTCTGCAAGGCGCG
GCAGGGCCCCGGCTCTTCACCATCCACCTGATTGACGCCAACACCGACAACCTGCCCAAGGCCC
ACACCTGCTTTAATCGGATTGACATCCCACCCTATGAGTCCTATGAGAAGCTCTATGAGAAGCT
GCTGACAGCGGTAGAGGAGACCTGTGGCTTTGCCGTGGAGTGAAGAGCAGCCCGTGGCCACAGA
GTCTTGCTCACAACCACCAGACCCAAAGCATATGGCGTCTGCGCGCCTCCCGCATGGCGGGCGG
AGGCCTGAGATTCCAGAAACCGAGGGAAAAGGCTCGTCTCCCTCCTCCTTTGGAGAAGGCAGGC
CAGGGGACTTTCATAGGTGGCTCCCACCCATTTATTCCTCCTTTATTATAGTTCGCCCACTCCT
CCATCACCCATCCAATAAAACGCAGCCAGGTTTCGCCCTCAGCCTCCTTGGCATGGTGGTAAGG
CTGTGGTGTCTCCGGGAGCATCAACCATGGTCAGGGCCAAGCTGGGCCCCGAGGGTTTGCGTGG
CCTCTGTACCAGCTCCCCCTCTAACTGTAGCCGCAAAGCCCCCTTTCAAGTTCAGCAGCTGCCA
ATAGCTTACTGATCTCAAATTCCAGAGGCCTCACAGGCTTGCAGCCTGTCCAGATAGCCGGTGG
ATCTCCAAGCAGGAGGTAAAGGCAGTGAATGCTTGCTGGAACTCCACTATGGTAGGAGACTCGA
GGCGATGTGTTTTCCCCTTTGAGAGGTAAAGGAATTGCAACAGCCTTCACTGGAAGCCTGGGTA
CTTTTCACAGTGTCCTGGCTAAAAATAAGGTTTTGCAGGGGAAAAAAATCTTTAAAAGTACAAT
TTGCTGTGTTCCCTACCCAGTTTGAAATTATCACGTCATGGAGCTAAGCAAAGAATAACCAAAA
CCAGCCTCTGACCCCTGGGTCCAGCTCAGTTTCTGTGCCTGGGGATCCAGAGGCTCCTAGCTGT
CTTGAAATGGACTCACATATGGGGATTGCTAAGAGCTAAACTAACAGAACAATTTTGTCACCGC
AGCCATTGGGTGGAACAGCAGGAGAGGCCGCTGACCTGGGGTCCCCTGATGTAGCTCCCCAGGG
TTGGTGCTGTGCACAGAGCAGGGTGTGGTGGGGCGCGTGGCAACAGGGTGGGGGCTTTACCTCC
CTACGTGGCCCTCTTCCCCATGGCAGCGGTGATGCTAACAGTTCTACTCAGTTTGCTTGCTCAG
TCTCCGAGCAAGGCCAAAGCCAGCCTAACACGTCTAACAGCACTTCCGGTCGCACACGGCTTCA
CAGACGTTGACTCTTACAGCCGAGCAGCTGGACTGAGACAGCTGAGCTCTGGTGGAAGGCAGGG
CAGCAGCCAGGTTTCCATTTGTAGTTTTGTTGTTTTTGTTTGTGGTGGGGGTGAGAACAGGGTA
ATTCATTAGCAAGACATTTCATTGGTACCAGGGCTCAGGTTCAGCCACGAGTTCAAGTTGTATG
GCAGATGATCAGGAAGGTCCTGTTGGGACACTGGCTTTTGTGGTTTTTCTGTTGCTTCCCCTCA
GGCTGAGGGTAGGGAAGTGTCTGCTGCTTCTGTCCAGTGTGGTCTGAAGCAGTGCTGAGGTGAT
AGGGGGAGTGGATTCATAGGGCACATACACCCCCTAACCGAAGAGATTTGTCCAGCTTGGCCAC
TGGCACTACAGAGCATGAGTCAGCTGCACTCTGGGTTGCCAGGGTGAGGATGCTAGGTAGACCT
CACTGCACAAGGACCGAACCCACCCCACCTCCCAGGCCAGACTGGGGCCTTATTAGTCTCTCAA
TTCTGCCTTGCCCCAGTAGGGCTTCTGTAATTCATCTACCTTCAAGCTTCTGAGGGTGTTCTAA
AACCCAGCTCCCTCATGACTCGTGGATTCAAAAGGCGCAAGGAAGCCTGTGTCCTAAGTCTCAG
CCAGTCCATAGGAAGCAACCAGACCCCACACAGTGACACACTTTCTGGAGACCAGAAACCTTGC
CTGTTGCCCTGGCACCGTCCAGACTGCAGTGATGAAGGACACCAGGGTTCTGTGCTTCGGGGAT
GTGTGCAGGAGTGTCAGGTCATACTGTTTGTGCCTCGGGAGTGATGGGGGACAAGCCTTAGGAG
TCCCGTGTCAGATGCCCTCAGAGGAAGATCCAGAGGCTGGGCCTTTAGGGGCCGACTGGCTGGC
ACACATGCCACCTACTAAGGCTTCTAACAGTCACTGTGCCTGCATTGCTCGTGGGTTCCCCTCA
TTGCCGGTTCTGAGTGTCACAACCTCCCCCAGGTCTGTTCATGCATAGCACTGTCGTCTGTTGG
TAGCGCTGCACTTCCTTGTCTGTCTACCATGGTTAGGCCCTTCTGACGCTCCTCAAAGACACTG
CGTGGCCGGCCCACGGCACAGCTCCTGGTTGCCCTGCTTGGGTCTGGGTGAAGCCCTTTCATGT
CAGACCTCGGTCGTCCTAGTGGCCACCATCACCCAGATGCTTCAGGAGTCCTGCTCTCCAGGCT
CCCCTCACCAGCGGCCGGCAGCCACACTCAGGGACGCAGCAAACACCACTCTGCTCGGCAGTGC
TTCAGAGAGGACACCAGGCTGCCGCAATGGTGTGGCAGCAGGTCGCCGTCTCCTGCTGTCTGTG
AGGAGACTCTGCCACAAGATGAGACGCTAACCCCTGGCCTGGCTTGGCCACAAGGTCAGGTTCA
GGTCGGGCGAACGCTGGACCGATCTGCAGAGAACACGCCTCATCCTACCGCAGCCTGGGGGCCA
CGTGGCAGCCTTCTGAAACAGTGTGGATTTTTAAACTGTGTTTATAATGTATTCTTATTTATTT
TGTAAGGTCCTGTTTGAAGTGCTGCTGCTACCCCTAGTTGCTCCCCCAGTTTTTATTGCCCATT
AACCTGTGACAGTTGTACACTAATGTTCTATGTCAGAATGGAAAGTATTTAAAGAAATGCTAGT
TCTATTTAATGCAGTCGTGGAACCAGCTGGAAACACAAAACGTTGACTGTACAGCAGGCTGGAC
CCGGGAGGTCAGGTTCATTTTGTTACATATGCAATAAACTCACAACTTTACTTTT

hide sequence

RefSeq Acc Id:

XM_039089789 ⟹ XP_038945717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,748,749 - 14,840,273 (+)	NCBI
mRatBN7.2	12	9,635,009 - 9,726,520 (+)	NCBI

RefSeq Acc Id:

XR_010056420

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	14,750,769 - 14,815,647 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001103068	(Get FASTA)	NCBI Sequence Viewer
	NP_001430791	(Get FASTA)	NCBI Sequence Viewer
	XP_006248944	(Get FASTA)	NCBI Sequence Viewer
	XP_008767224	(Get FASTA)	NCBI Sequence Viewer
	XP_017453951	(Get FASTA)	NCBI Sequence Viewer
	XP_038945717	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89624	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031927
	ENSRNOP00000031927.6
	ENSRNOP00000071653
	ENSRNOP00000071653.2
	ENSRNOP00000073635
	ENSRNOP00000073635.2
	ENSRNOP00000076358.2

RefSeq Acc Id:

NP_001103068 ⟸ NM_001109598

- UniProtKB:

D3ZCF5 (UniProtKB/TrEMBL), A6K1G6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQ
HYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDA
VRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGG
GNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQ
TGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQ
CQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFE
ESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQ
INPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKS
LVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEA
QFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAV
ETFDEERRARLLQFVTGSTRVPLQGFKALQGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPP
YESYEKLYEKLLTAVEETCGFAVE

hide sequence

RefSeq Acc Id:	XP_006248944 ⟸ XM_006248882
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2K612 (UniProtKB/TrEMBL), D3ZCF5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQ HYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDA VRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGG GNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQ TGVSTWHDPRIPSPLGTIPGGDEAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSG RIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKV LRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWL YLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTV PFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRN VPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDL NDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGP RLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE hide sequence

RefSeq Acc Id:	XP_008767224 ⟸ XM_008769002
- Peptide Label:	isoform X2
- UniProtKB:	D3ZCF5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQ HYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDA VRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGG GNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQ TGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQ CQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFE ESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQ INPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKS LVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEA QFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAV ETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRID IPPYESYEKLYEKLLTAVEETCGFAVE hide sequence

RefSeq Acc Id:	XP_017453951 ⟸ XM_017598462
- Peptide Label:	isoform X1
- UniProtKB:	D3ZCF5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQ HYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTDA VRGQIVVSLQTRDRIGGGGSVVDCRGLLENEGTVYEDSGPGRPLSCLMEEPAPYTDGTGAAAGG GNCRFVESPSQDQRLLVQRLRNPEVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQ TGVSTWHDPRIPSPLGTIPGGDEAFLYEFLLQGHTSEPRDLNSVNCDELGPLPPGWEVRSTVSG RIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLQLPSEGSVEDEELPAQRYERDLVQKLKV LRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWL YLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTV PFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRN VPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDL NDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGAAGPRLF TIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE hide sequence

Ensembl Acc Id:

ENSRNOP00000071653 ⟸ ENSRNOT00000082989

Ensembl Acc Id:

ENSRNOP00000073635 ⟸ ENSRNOT00000084577

Ensembl Acc Id:

ENSRNOP00000031927 ⟸ ENSRNOT00000031901

RefSeq Acc Id:	XP_038945717 ⟸ XM_039089789
- Peptide Label:	isoform X3
- UniProtKB:	D3ZCF5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000076358 ⟸ ENSRNOT00000112221

Protein Domains

C2 HECT WW

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K612-F1-model_v2	AlphaFold	A0A0G2K612	1-731	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1594738	AgrOrtholog
BioCyc Gene	G2FUF-20049	BioCyc
Ensembl Genes	ENSRNOG00000000999	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031901	ENTREZGENE
	ENSRNOT00000031901.8	UniProtKB/TrEMBL
	ENSRNOT00000082989	ENTREZGENE
	ENSRNOT00000082989.3	UniProtKB/TrEMBL
	ENSRNOT00000084577	ENTREZGENE
	ENSRNOT00000084577.3	UniProtKB/TrEMBL
	ENSRNOT00000112221.2	UniProtKB/TrEMBL
Gene3D-CATH	2.20.70.10	UniProtKB/TrEMBL
	2.60.40.150	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domain	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domain	UniProtKB/TrEMBL
	Hect, E3 ligase catalytic domains	UniProtKB/TrEMBL
InterPro	C2_Ca-dep	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	E3_ub_ligase_SMURF1	UniProtKB/TrEMBL
	E3_ubiq-protein_ligase	UniProtKB/TrEMBL
	HECT	UniProtKB/TrEMBL
	Hect_E3_ubiquitin_ligase	UniProtKB/TrEMBL
	WW_dom_sf	UniProtKB/TrEMBL
	WW_Rsp5_WWP	UniProtKB/TrEMBL
KEGG Report	rno:690516	UniProtKB/TrEMBL
NCBI Gene	690516	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE SMURF1	UniProtKB/TrEMBL
	HECT DOMAIN UBIQUITIN-PROTEIN LIGASE	UniProtKB/TrEMBL
Pfam	HECT	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
	PF00397	UniProtKB/TrEMBL
PhenoGen	Smurf1	PhenoGen
PIRSF	E3_ub_ligase_SMURF1	UniProtKB/TrEMBL
PROSITE	HECT	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
	WW_DOMAIN_1	UniProtKB/TrEMBL
	WW_DOMAIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000999	RatGTEx
SMART	HECTc	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
	SM00456	UniProtKB/TrEMBL
Superfamily-SCOP	HECT	UniProtKB/TrEMBL
	SSF49562	UniProtKB/TrEMBL
	WW_Rsp5_WWP	UniProtKB/TrEMBL
UniProt	A0A0G2K105_RAT	UniProtKB/TrEMBL
	A0A0G2K612	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZK23_RAT	UniProtKB/TrEMBL
	A6K1G6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZCF5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Smurf1	SMAD specific E3 ubiquitin protein ligase 1	LOC690516	similar to Smad ubiquitination regulatory factor 1 isoform 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-07-08	LOC690516	similar to Smad ubiquitination regulatory factor 1 isoform 2	RGD1309707	similar to RIKEN cDNA 4930431E10	Data merged from RGD:1309707	1643240	APPROVED
2008-04-30	RGD1309707	similar to RIKEN cDNA 4930431E10	RGD1309707_predicted	similar to RIKEN cDNA 4930431E10 (predicted)	'predicted' is removed	2292626	APPROVED
2006-11-20	LOC690516	similar to Smad ubiquitination regulatory factor 1 isoform 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-20	RGD1309707_predicted	similar to RIKEN cDNA 4930431E10 (predicted)	LOC288469_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC288469_predicted	similar to RIKEN cDNA 4930431E10 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)