MIR375 (microRNA 375) - Rat Genome Database

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Gene: MIR375 (microRNA 375) Homo sapiens
Analyze
Symbol: MIR375
Name: microRNA 375
RGD ID: 1345165
HGNC Page HGNC:31868
Description: Involved in negative regulation of sprouting angiogenesis and positive regulation of endothelial cell apoptotic process. Located in extracellular space. Biomarker of bacterial gastritis and stomach cancer.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: hsa-mir-375; mir-375; MIRN375; miRNA375
RGD Orthologs
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,001,645 - 219,001,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,001,645 - 219,001,708 (-)Ensemblhg38GRCh38
GRCh372219,866,367 - 219,866,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,574,610 - 219,574,673 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2213,636,080 - 213,636,143 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,720,395 - 211,720,458 (-)NCBIHuRef
CHM1_12219,873,820 - 219,873,883 (-)NCBICHM1_1
T2T-CHM13v2.02219,490,020 - 219,490,083 (-)NCBIT2T-CHM13v2.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. Miao L, etal., Cancer Immunol Immunother. 2014 Jul;63(7):699-711. doi: 10.1007/s00262-014-1550-y. Epub 2014 Apr 10.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15538371   PMID:16381832   PMID:17604727   PMID:20102393   PMID:20226166   PMID:20467341   PMID:20548334   PMID:20978187   PMID:21037258   PMID:21343377   PMID:21533613   PMID:21593139  
PMID:21673684   PMID:21723283   PMID:21753766   PMID:21813472   PMID:21856745   PMID:21953071   PMID:22031094   PMID:22056881   PMID:22172490   PMID:22302717   PMID:22377847   PMID:22469014  
PMID:22508479   PMID:22519435   PMID:22752059   PMID:22987659   PMID:23103713   PMID:23206448   PMID:23259291   PMID:23301089   PMID:23552692   PMID:23574937   PMID:23581226   PMID:23651447  
PMID:23685355   PMID:23696927   PMID:23778521   PMID:23835407   PMID:23864342   PMID:23897763   PMID:24120394   PMID:24166096   PMID:24173286   PMID:24390317   PMID:24404590   PMID:24440701  
PMID:24469711   PMID:24481267   PMID:24533739   PMID:24571711   PMID:24680681   PMID:24708873   PMID:24741571   PMID:24746361   PMID:24846066   PMID:25001509   PMID:25055044   PMID:25059983  
PMID:25169436   PMID:25184138   PMID:25255814   PMID:25307786   PMID:25330011   PMID:25336585   PMID:25501018   PMID:25521481   PMID:25618599   PMID:25633534   PMID:25666256   PMID:25695220  
PMID:25726255   PMID:25754273   PMID:25769078   PMID:25814440   PMID:25875172   PMID:25992776   PMID:26013143   PMID:26036761   PMID:26107137   PMID:26124181   PMID:26172508   PMID:26219823  
PMID:26224081   PMID:26224477   PMID:26235810   PMID:26349912   PMID:26474386   PMID:26507573   PMID:26642205   PMID:26646931   PMID:26681654   PMID:26697569   PMID:26806295   PMID:26806656  
PMID:26818914   PMID:26877261   PMID:26962366   PMID:27016415   PMID:27036030   PMID:27129171   PMID:27206217   PMID:27222350   PMID:27270433   PMID:27276676   PMID:27279635   PMID:27440205  
PMID:27449098   PMID:27531059   PMID:27832783   PMID:27862697   PMID:27885434   PMID:28000902   PMID:28006751   PMID:28017506   PMID:28069583   PMID:28075453   PMID:28078305   PMID:28098887  
PMID:28214218   PMID:28254488   PMID:28262546   PMID:28278515   PMID:28300567   PMID:28374902   PMID:28439875   PMID:28443609   PMID:28499703   PMID:28533502   PMID:28618945   PMID:28627030  
PMID:28670764   PMID:28688608   PMID:28802228   PMID:28810236   PMID:28861609   PMID:28973164   PMID:29033189   PMID:29089067   PMID:29105802   PMID:29115164   PMID:29210193   PMID:29245068  
PMID:29259977   PMID:29298817   PMID:29328389   PMID:29367737   PMID:29428732   PMID:29439669   PMID:29487354   PMID:29522716   PMID:29722068   PMID:29776561   PMID:29871889   PMID:29930741  
PMID:30025897   PMID:30033809   PMID:30061360   PMID:30098579   PMID:30143449   PMID:30203041   PMID:30243807   PMID:30302825   PMID:30353914   PMID:30500346   PMID:30514309   PMID:30549196  
PMID:30638952   PMID:30670062   PMID:30728448   PMID:30744636   PMID:30763770   PMID:30784283   PMID:30850595   PMID:30879885   PMID:31199037   PMID:31355469   PMID:31372832   PMID:31527801  
PMID:31539144   PMID:31643074   PMID:31787478   PMID:31802830   PMID:31882195   PMID:31882475   PMID:31937854   PMID:31976033   PMID:31983094   PMID:31983104   PMID:32073706   PMID:32128886  
PMID:32130980   PMID:32215815   PMID:32280708   PMID:32282768   PMID:32335541   PMID:32382558   PMID:32476381   PMID:32513696   PMID:32564679   PMID:32582987   PMID:32616906   PMID:32619704  
PMID:32698859   PMID:32708220   PMID:32716585   PMID:32726125   PMID:32728103   PMID:32738343   PMID:32784653   PMID:32856881   PMID:32940043   PMID:33158661   PMID:33255991   PMID:33311552  
PMID:33328332   PMID:33372873   PMID:33398380   PMID:33407703   PMID:33433801   PMID:33450254   PMID:33535081   PMID:33595945   PMID:33668431   PMID:33744323   PMID:33785715   PMID:33854485  
PMID:33928819   PMID:33938607   PMID:34001972   PMID:34090492   PMID:34132362   PMID:34148288   PMID:34310809   PMID:34626803   PMID:34643249   PMID:34699320   PMID:34711123   PMID:34818025  
PMID:34906568   PMID:35022519   PMID:35075615   PMID:35094987   PMID:35127344   PMID:35230198   PMID:35269556   PMID:35461395   PMID:35468741   PMID:35532539   PMID:35688898   PMID:35763793  
PMID:35953439   PMID:36042375   PMID:36190453   PMID:36203260   PMID:36476264   PMID:36600625   PMID:36701095   PMID:36749234   PMID:37303180   PMID:37625279   PMID:37681934   PMID:38139275  
PMID:38431920   PMID:38505381   PMID:38622668   PMID:38820252  


Genomics

Comparative Map Data
MIR375
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,001,645 - 219,001,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,001,645 - 219,001,708 (-)Ensemblhg38GRCh38
GRCh372219,866,367 - 219,866,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,574,610 - 219,574,673 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2213,636,080 - 213,636,143 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,720,395 - 211,720,458 (-)NCBIHuRef
CHM1_12219,873,820 - 219,873,883 (-)NCBICHM1_1
T2T-CHM13v2.02219,490,020 - 219,490,083 (-)NCBIT2T-CHM13v2.0
Mir375
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,939,817 - 74,939,880 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,939,817 - 74,939,880 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38174,900,658 - 74,900,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,900,658 - 74,900,721 (-)Ensemblmm10GRCm38
MGSCv37174,947,232 - 74,947,295 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera175,455,688 - 75,455,751 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.54NCBI
Mir375
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,906,582 - 83,906,656 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2976,457,911 - 76,457,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,457,911 - 76,457,985 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx984,902,918 - 84,902,992 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0990,031,868 - 90,031,942 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,418,026 - 88,418,100 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,161,716 - 82,161,790 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,161,716 - 82,161,790 (-)Ensemblrn6Rnor6.0
Rnor_5.0981,930,296 - 81,930,370 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera974,029,377 - 74,029,451 (-)NCBICelera
Cytogenetic Map9q33NCBI
MIR375
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,568,052 - 25,568,121 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,568,052 - 25,568,127 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3726,388,246 - 26,388,315 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03725,583,487 - 25,583,556 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3725,583,487 - 25,583,562 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13725,488,066 - 25,488,135 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,423,157 - 25,423,226 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,443,921 - 25,443,990 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q32.3-37.3(chr2:194898783-236473913)x3 copy number gain See cases [RCV000051119] Chr2:194898783..236473913 [GRCh38]
Chr2:195763507..237382556 [GRCh37]
Chr2:195471752..237047295 [NCBI36]
Chr2:2q32.3-37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:188818195-242065208)x3 copy number gain See cases [RCV000052958] Chr2:188818195..242065208 [GRCh38]
Chr2:189682921..243007359 [GRCh37]
Chr2:189391166..242656032 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:190310736-241892770)x3 copy number gain See cases [RCV000052959] Chr2:190310736..241892770 [GRCh38]
Chr2:191175462..242834921 [GRCh37]
Chr2:190883707..242483594 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:193122313-241074980)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|See cases [RCV000052960] Chr2:193122313..241074980 [GRCh38]
Chr2:193987039..242014395 [GRCh37]
Chr2:193695284..241663068 [NCBI36]
Chr2:2q32.3-37.3		 pathogenic
GRCh38/hg38 2q34-36.3(chr2:212614422-227121230)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052964]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052964]|See cases [RCV000052964] Chr2:212614422..227121230 [GRCh38]
Chr2:213479146..227985946 [GRCh37]
Chr2:213187391..227694190 [NCBI36]
Chr2:2q34-36.3		 pathogenic
GRCh38/hg38 2q34-37.3(chr2:210579676-242126245)x3 copy number gain See cases [RCV000135934] Chr2:210579676..242126245 [GRCh38]
Chr2:211444400..243059659 [GRCh37]
Chr2:211152645..242717069 [NCBI36]
Chr2:2q34-37.3		 pathogenic
GRCh38/hg38 2q31.3-36.2(chr2:180513793-224302848)x3 copy number gain See cases [RCV000139446] Chr2:180513793..224302848 [GRCh38]
Chr2:181378520..225167565 [GRCh37]
Chr2:181086765..224875809 [NCBI36]
Chr2:2q31.3-36.2		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:189436149-241841232)x3 copy number gain See cases [RCV000142307] Chr2:189436149..241841232 [GRCh38]
Chr2:190300875..242783384 [GRCh37]
Chr2:190009120..242432057 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q35-37.3(chr2:218101759-242126245)x3 copy number gain See cases [RCV000143216] Chr2:218101759..242126245 [GRCh38]
Chr2:218966482..243059659 [GRCh37]
Chr2:218674727..242717069 [NCBI36]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q35-36.3(chr2:217374144-227643620)x1 copy number loss not provided [RCV000585275] Chr2:217374144..227643620 [GRCh37]
Chr2:2q35-36.3		 likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q34-37.3(chr2:213518431-242783384)x3 copy number gain See cases [RCV000512009] Chr2:213518431..242783384 [GRCh37]
Chr2:2q34-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q35-37.3(chr2:219225872-242016876)x3 copy number gain not provided [RCV000682170] Chr2:219225872..242016876 [GRCh37]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q35-36.3(chr2:218813434-227450699)x1 copy number loss not provided [RCV000682163] Chr2:218813434..227450699 [GRCh37]
Chr2:2q35-36.3		 pathogenic
NC_000002.11:g.(?_219135239)_(220290732_?)del deletion Desmin-related myofibrillar myopathy [RCV000707774] Chr2:219135239..220290732 [GRCh37]
Chr2:2q35		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
Single allele duplication Neurodevelopmental disorder [RCV000787403] Chr2:188926928..225298653 [GRCh37]
Chr2:2q32.1-36.2		 pathogenic
GRCh37/hg19 2q34-37.3(chr2:210779657-239879183)x3 copy number gain See cases [RCV000790568] Chr2:210779657..239879183 [GRCh37]
Chr2:2q34-37.3		 pathogenic
GRCh37/hg19 2q35(chr2:216883237-220953003)x3 copy number gain not provided [RCV001007510] Chr2:216883237..220953003 [GRCh37]
Chr2:2q35		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q34-35(chr2:215122019-220397907)x1 copy number loss not provided [RCV001259180] Chr2:215122019..220397907 [GRCh37]
Chr2:2q34-35		 likely pathogenic
GRCh37/hg19 2q31.2-37.3(chr2:178397959-243007457)x3 copy number gain See cases [RCV001263052] Chr2:178397959..243007457 [GRCh37]
Chr2:2q31.2-37.3		 pathogenic
GRCh37/hg19 2q35(chr2:219797684-220088582)x3 copy number gain not provided [RCV001259184] Chr2:219797684..220088582 [GRCh37]
Chr2:2q35		 uncertain significance
GRCh37/hg19 2q35-37.3(chr2:219606537-239217703) copy number loss not specified [RCV002053285] Chr2:219606537..239217703 [GRCh37]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q34-36.1(chr2:215108009-221679980) copy number gain not specified [RCV002053282] Chr2:215108009..221679980 [GRCh37]
Chr2:2q34-36.1		 pathogenic
GRCh37/hg19 2q35(chr2:218210665-220141650) copy number gain not specified [RCV002053284] Chr2:218210665..220141650 [GRCh37]
Chr2:2q35		 uncertain significance
NC_000002.11:g.(?_218999525)_(220435954_?)dup duplication Alacrima, achalasia, and intellectual disability syndrome [RCV001955103]|Paroxysmal nonkinesigenic dyskinesia [RCV001962531] Chr2:218999525..220435954 [GRCh37]
Chr2:2q35		 uncertain significance
GRCh37/hg19 2q32.1-36.1(chr2:186698504-223918111)x3 copy number gain See cases [RCV003329558] Chr2:186698504..223918111 [GRCh37]
Chr2:2q32.1-36.1		 pathogenic
GRCh37/hg19 2q35-37.3(chr2:218376403-242783384)x3 copy number gain not provided [RCV003484087] Chr2:218376403..242783384 [GRCh37]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q35-37.3(chr2:216815496-242782258)x3 copy number gain See cases [RCV004442836] Chr2:216815496..242782258 [GRCh37]
Chr2:2q35-37.3		 pathogenic
NC_000002.11:g.(?_219646906)_(219942948_?)dup duplication not provided [RCV004583773] Chr2:219646906..219942948 [GRCh37]
Chr2:2q35		 uncertain significance
GRCh37/hg19 2q35(chr2:219275536-220266647)x3 copy number gain See cases [RCV000511655] Chr2:219275536..220266647 [GRCh37]
Chr2:2q35		 uncertain significance
miRNA Target Status (No longer updated)

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
TIMM8Ahsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19734348
TIMM8Ahsa-miR-375Mirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//MFunctional MTI19807270
MTPNhsa-miR-375Mirtarbaseexternal_infoReporter assay;OtherFunctional MTI15538371
PDK1hsa-miR-375Mirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//qFunctional MTI21533613
PDK1hsa-miR-375Mirtarbaseexternal_infoWestern blotFunctional MTI20215506
USP1hsa-miR-375Mirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)20215506
USP1hsa-miR-375Mirtarbaseexternal_infoReporter assayFunctional MTI15806104
JAK2hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assay//Western blot//Reporter Functional MTI20548334
PLAG1hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19347935
MTDHhsa-miR-375Mirtarbaseexternal_infoImmunofluorescence//Luciferase reporter assay//qRTFunctional MTI22508479
RASD1hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCRFunctional MTI20978187
YY1AP1hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20226166
ELAVL4hsa-miR-375Mirtarbaseexternal_infoGFP reporter assay//Immunohistochemistry//MicroarrFunctional MTI20584986
MAP3K8hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23430746
RAB10hsa-miR-375Mirtarbaseexternal_infoqRT-PCR;MicroarrayFunctional MTI (Weak)20584986
FZD8hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23393589
FZD8hsa-miR-375Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23396279
BCL2L11hsa-miR-375Mirtarbaseexternal_infoMicroarray//qRT-PCR;MicroarrayFunctional MTI (Weak)20215506
YWHAZhsa-miR-375Mirtarbaseexternal_infoReporter assay;Western blot;qRT-PCR;MicroarrayFunctional MTI20215506
RHOAhsa-miR-375Mirtarbaseexternal_infoWestern blot;qRT-PCR;MicroarrayFunctional MTI20584986
AHRhsa-miR-375Tarbaseexternal_infoOtherNEGATIVE
C1QBPhsa-miR-375Tarbaseexternal_infoReporter GenePOSITIVE
EIF4EBP2hsa-miR-375Tarbaseexternal_infoMicroarrayPOSITIVE
YAP1hsa-miR-375Mirecordsexternal_infoNANA20100814
RAB10hsa-miR-375Tarbaseexternal_infoqPCRPOSITIVE
JAK2hsa-miR-375Tarbaseexternal_infoWesternblitPOSITIVE
ELAVL4hsa-miR-375Tarbaseexternal_infoOtherPOSITIVE
YWHAZhsa-miR-375Mirecordsexternal_info{changed}NA20215506
JAK2hsa-miR-375Mirecordsexternal_info{unchanged}NA20548334
MTDHhsa-miR-375OncomiRDBexternal_infoNANA22508479
ATG7hsa-miR-375OncomiRDBexternal_infoNANA22504094
MTDHhsa-miR-375OncomiRDBexternal_infoNANA22056881
MTDHhsa-miR-375OncomiRDBexternal_infoNANA22031094
SP1hsa-miR-375OncomiRDBexternal_infoNANA21945323
LDHBhsa-miR-375OncomiRDBexternal_infoNANA21922130
YAP1hsa-miR-375OncomiRDBexternal_infoNANA21856745
IGF1Rhsa-miR-375OncomiRDBexternal_infoNANA21813472
MTDHhsa-miR-375OncomiRDBexternal_infoNANA21753766
SEC23Ahsa-miR-375OncomiRDBexternal_infoNANA21593139
YAP1hsa-miR-375OncomiRDBexternal_infoNANA20226166
PDK1hsa-miR-375OncomiRDBexternal_infoNANA21533613
RASD1hsa-miR-375OncomiRDBexternal_infoNANA20978187
JAK2hsa-miR-375OncomiRDBexternal_infoNANA20548334
YWHAZhsa-miR-375OncomiRDBexternal_infoNANA20215506

Predicted Targets
Summary Value
Count of predictions:3706
Count of gene targets:1924
Count of transcripts:3172
Interacting mature miRNAs:hsa-miR-375
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293458PRSTS291_HProstate tumor susceptibility QTL 291 (human)0.012Prostate tumor susceptibility2200715236226715236Human
1643053BW117_HBody Weight QTL 117 (human)2.40.00044Body weight2200715236226715236Human
2289332BW376_HBody weight QTL 376 (human)1.870.00168Body fat amountabdominal2213765566239765566Human
1643254BW125_HBody Weight QTL 125 (human)1.450.005Body weightbody mass index2200715236226715236Human


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
37 177 166 153 114 34 116 2 6 58 4 55 410 333 2 99 23 61 95 3

Sequence


Ensembl Acc Id: ENST00000362103
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2219,001,645 - 219,001,708 (-)Ensembl
RefSeq Acc Id: NR_029867
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382219,001,645 - 219,001,708 (-)NCBI
GRCh372219,866,367 - 219,866,430 (-)RGD
Celera2213,636,080 - 213,636,143 (-)RGD
HuRef2211,720,395 - 211,720,458 (-)ENTREZGENE
CHM1_12219,873,820 - 219,873,883 (-)NCBI
T2T-CHM13v2.02219,490,020 - 219,490,083 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31868 AgrOrtholog
COSMIC MIR375 COSMIC
Ensembl Genes ENSG00000198973 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000362103 ENTREZGENE
GTEx ENSG00000198973 GTEx
HGNC ID HGNC:31868 ENTREZGENE
Human Proteome Map MIR375 Human Proteome Map
miRBase MI0000783 ENTREZGENE
NCBI Gene 494324 ENTREZGENE
OMIM 611173 OMIM
PharmGKB PA164722691 PharmGKB
RNAcentral URS00000ED600 RNACentral
  URS000075BCF9 RNACentral
  URS000075CCDA RNACentral