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Gene: Slc30a8 (solute carrier family 30 member 8) Rattus norvegicus

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Symbol:

Slc30a8

Name:

solute carrier family 30 member 8

RGD ID:

1308282

Description:

Enables zinc ion transmembrane transporter activity. Involved in several processes, including intracellular zinc ion homeostasis; positive regulation of insulin secretion; and zinc ion import across plasma membrane. Predicted to be located in secretory granule membrane. Predicted to be active in plasma membrane and secretory granule. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC30A8 (solute carrier family 30 member 8); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; aldehydo-D-glucose; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC299903; proton-coupled zinc antiporter SLC30A8; solute carrier family 30 (zinc transporter), member 8; zinc transporter 8; ZnT-8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC30A8 (solute carrier family 30 member 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc30a8 (solute carrier family 30 (zinc transporter), member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc30a8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC30A8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC30A8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc30a8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC30A8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC30A8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc30a8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Slc30a8 (solute carrier family 30 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC30A8 (solute carrier family 30 member 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc30a8 (solute carrier family 30 (zinc transporter), member 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc30a8 (solute carrier family 30 member 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc30a8 (solute carrier family 30 member 8)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	cdf-2	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ZnT33D	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	ZnT33D	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ZnT35C	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc30a8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Slc30a8^em1Mcwi ; Slc30a8^em2Mcwi

Genetic Models:

SS-Slc30a8^em1Mcwi ; SS-Slc30a8^em2Mcwi

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	85,481,864 - 85,517,177 (+)	Ensembl				GRCr8
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	85,509,786 - 85,542,609 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	87,710,991 - 87,743,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	87,515,694 - 87,548,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	91,832,988 - 91,867,300 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	80,455,350 - 80,488,134 (+)	NCBI		Celera
RGSC_v3.1	7	88,604,575 - 88,639,923 (+)	NCBI
Cytogenetic Map	7	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

maturity-onset diabetes of the young type 1 (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3-iodothyronamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (EXP,ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

D-glucose (EXP,ISO)

dichloroacetic acid (ISO)

diquat (ISO)

entinostat (ISO)

epoxiconazole (ISO)

fulvestrant (ISO)

glucose (EXP,ISO)

glyphosate (EXP)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (EXP)

paracetamol (ISO)

potassium chloride (EXP)

sodium arsenite (ISO)

trichloroethene (EXP)

triclosan (ISO)

valproic acid (ISO)

zinc atom (EXP,ISO)

zinc(0) (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glucose homeostasis (ISO)

insulin processing (IEA,ISO)

insulin secretion (IBA,IEA,IMP,ISO)

intracellular zinc ion homeostasis (IEA,IMP,ISO)

monoatomic cation transport (IEA)

monoatomic ion transport (IEA)

positive regulation of insulin secretion (IMP)

regulation of vesicle-mediated transport (IMP)

response to glucose (IBA,IEA,IMP,ISO)

response to interleukin-1 (IEP)

response to type II interferon (IEP)

response to zinc ion (IBA)

transmembrane transport (IEA)

zinc ion import across plasma membrane (IMP)

zinc ion import into organelle (IEA,ISO,ISS)

zinc ion transmembrane transport (IBA)

zinc ion transport (IEA,ISO)

Cellular Component

cytoplasmic vesicle (IEA,ISO)

Golgi apparatus (ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

secretory granule (IEA,ISO)

secretory granule membrane (IEA,ISO,ISS)

transmembrane transporter complex (IEA,ISO)

transport vesicle membrane (IEA)

Molecular Function

antiporter activity (IEA)

metal ion binding (IEA)

monoatomic cation transmembrane transporter activity (IEA)

protein binding (ISO)

protein homodimerization activity (IEA,ISO)

zinc ion transmembrane transporter activity (IBA,IEA,IMP,ISO)

zinc:proton antiporter activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?	Egefjord L, etal., BMC Endocr Disord. 2009 Feb 25;9(1):7.
2.	Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion.	Fu Y, etal., PLoS One. 2009 May 25;4(5):e5679.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands.	Murgia C, etal., Nutr Metab Cardiovasc Dis. 2009 Jul;19(6):431-9. Epub 2008 Dec 17.
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:15331542	PMID:16984975	PMID:19450229	PMID:19706465	PMID:21208276	PMID:23209723	PMID:26281917	PMID:26720469

Genomics

Comparative Map Data

Slc30a8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	85,481,864 - 85,517,177 (+)	Ensembl				GRCr8
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	85,509,786 - 85,542,609 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	87,710,991 - 87,743,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	87,515,694 - 87,548,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	91,832,988 - 91,867,300 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	80,455,350 - 80,488,134 (+)	NCBI		Celera
RGSC_v3.1	7	88,604,575 - 88,639,923 (+)	NCBI
Cytogenetic Map	7	q31	NCBI

SLC30A8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	116,950,217 - 117,176,714 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	116,950,273 - 117,176,714 (+)	Ensembl			hg38	GRCh38
GRCh37	8	117,962,456 - 118,188,953 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	118,216,518 - 118,258,134 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	118,216,747 - 118,254,101	NCBI
Celera	8	114,151,202 - 114,377,691 (+)	NCBI		Celera
Cytogenetic Map	8	q24.11	NCBI
HuRef	8	113,288,921 - 113,515,635 (+)	NCBI		HuRef
CHM1_1	8	118,002,722 - 118,228,963 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	118,078,388 - 118,305,142 (+)	NCBI		T2T-CHM13v2.0

Slc30a8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	52,158,949 - 52,199,194 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	52,158,949 - 52,199,194 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	52,295,553 - 52,335,798 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	52,295,553 - 52,335,798 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	52,127,108 - 52,167,288 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	52,125,636 - 52,165,816 (+)	NCBI		MGSCv36	mm8
Celera	15	53,863,656 - 53,904,335 (+)	NCBI		Celera
Cytogenetic Map	15	C	NCBI
cM Map	15	19.88	NCBI

Slc30a8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	23,207,146 - 23,236,874 (+)	Ensembl
ChiLan1.0	NW_004955417	23,207,146 - 23,239,170 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC30A8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	134,356,700 - 134,583,629 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	109,872,083 - 110,098,929 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	113,624,785 - 113,851,633 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	116,167,700 - 116,394,095 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	116,223,595 - 116,394,095 (+)	Ensembl			panPan2	panpan1.1

SLC30A8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	16,602,255 - 16,637,299 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	16,601,912 - 16,635,880 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	16,603,610 - 16,638,559 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	16,898,497 - 16,933,443 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	16,898,295 - 16,932,026 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	16,635,055 - 16,670,008 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	16,734,977 - 16,770,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	16,978,714 - 17,013,658 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc30a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	21,687,819 - 21,725,947 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	29,114,713 - 29,151,993 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	29,114,713 - 29,151,993 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC30A8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	21,517,486 - 21,555,746 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	21,517,009 - 21,557,747 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	22,786,105 - 22,824,455 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC30A8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	111,588,517 - 111,819,908 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	111,769,181 - 111,815,885 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	28,509,132 - 28,557,839 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc30a8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	15,431,806 - 15,461,833 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624763	15,393,221 - 15,469,819 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc30a8
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	226,830,416 - 226,864,732 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc30a8
261 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	112
Count of miRNA genes:	92
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000006410
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	45113903	90113903	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	71103011	106126789	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	51700643	96700643	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
1298525	Cm1	Cardiac mass QTL 1	2.7		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	7	56625161	101625161	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	63889858	108889858	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	55498584	105834451	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	48475049	93475049	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
1641908	Teswt1	Testicular weight QTL 1	3.28		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	7	82111245	96700643	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
724537	Niddm52	Non-insulin dependent diabetes mellitus QTL 52		0.02	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	82111245	95485241	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	62963207	107963207	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	63889858	108889858	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
2303582	Gluco53	Glucose level QTL 53	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	7	48603087	93603087	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

D7Rat141

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	83,591,953 - 83,592,070 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	91,832,949 - 91,833,065	NCBI	Rnor6.0
Rnor_5.0	7	92,475,985 - 92,476,101	UniSTS	Rnor5.0
RGSC_v3.4	7	88,583,730 - 88,583,847	RGD	RGSC3.4
RGSC_v3.4	7	88,583,731 - 88,583,847	UniSTS	RGSC3.4
Celera	7	80,455,311 - 80,455,427	UniSTS
RGSC_v3.1	7	88,604,461 - 88,604,577	RGD
RH 3.4 Map	7	573.4	RGD
RH 3.4 Map	7	573.4	UniSTS
RH 2.0 Map	7	490.3	RGD
SHRSP x BN Map	7	50.08	RGD
Cytogenetic Map	7	q31	UniSTS

Genetic Models

This gene Slc30a8 is modified in the following models/strains:

SS-Slc30a8^em1Mcwi SS-Slc30a8^em2Mcwi

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	6	38	86	68	66	39	22	39	6	150	79	1	65	16	60	27	8	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001130538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006410 ⟹ ENSRNOP00000006410

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	85,481,864 - 85,517,177 (+)	Ensembl
mRatBN7.2 Ensembl	7	83,591,993 - 83,626,305 (+)	Ensembl
Rnor_6.0 Ensembl	7	91,832,988 - 91,865,774 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079792 ⟹ ENSRNOP00000069455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	91,833,297 - 91,867,300 (+)	Ensembl

RefSeq Acc Id:

NM_001130538 ⟹ NP_001124010

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,481,864 - 85,514,650 (+)	NCBI
mRatBN7.2	7	83,591,993 - 83,624,779 (+)	NCBI
Rnor_6.0	7	91,832,988 - 91,865,774 (+)	NCBI
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI
RGSC_v3.4	7	88,583,770 - 88,617,145 (+)	RGD
Celera	7	80,455,350 - 80,488,134 (+)	RGD

Sequence:

show sequence

ATGTGTACACACACACACACACACACACACACACACACACTTTTTAGGATTCCATTTTCCAGTC
TCCCAGAAAAGCAGTTTCTGTGGGTGATAGAATGAGTCCAAGTGATCATCCAAGAAGACCGTTA
ATTTTCACAGACCTACCAACAGCACTGATGTAGGACGCACTATTAACTCAAGTACTGGAAGGAT
TTTTCTATTTTCTTAGGAAGTTGTGTGAATATAATAATCTCAGTGCTTCTTTACTTCCAAAACT
GGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCCCTGCTACCATGGAGTTTCT
TGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGCCTTCACTTCAGACAGAGAA
CGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGACGGGCCAGAGCGTCCGGAGGCAG
GAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGAACAGGTCGAGCAAGCAAGTGCA
TGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTTCTTTATGGTGGCAGAGGTGGTG
GGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCTGCTCATCTCTTAATTGACCTGA
CTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAAGGCCCCCTTCCAAGCGGCTGAC
ATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTCTGTCCTTTGCATCTGGGTGGTG
ACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTATCCTGATTACCAGATCCAAGCAG
GCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACATTGTACTAACTCTGATTTTGCA
CCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAATGCCAGCGTTCGAGCGGCCTTT
GTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTAATTAGTGCTCTCATTATCTACT
TTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTATCTCTTCCGTCTTGGCTTTGGC
CAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCATGGAAGGTGTTCCAAAGGGCCTG
AGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGCGTGATCTCCGTGCACAATCTAC
ACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTCATGTTGCTACAGGTCAGTGA

hide sequence

RefSeq Acc Id:

XM_006241645 ⟹ XP_006241707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,481,864 - 85,517,255 (+)	NCBI
mRatBN7.2	7	83,591,993 - 83,627,786 (+)	NCBI
Rnor_6.0	7	91,832,988 - 91,869,329 (+)	NCBI
Rnor_5.0	7	92,476,024 - 92,512,365 (+)	NCBI

Sequence:

show sequence

ATGTGTACACACACACACACACACACACACACACACACACTTTTTAGGATTCCATTTTCCAGTC
TCCCAGAAAAGCAGTTTCTGTGGGTGATAGAATGAGTCCAAGTGATCATCCAAGAAGACCGTTA
ATTTTCACAGACCTACCAACAGCACTGATGTAGGACGCACTATTAACTCAAGTACTGGAAGGAT
TTTTCTATTTTCTTAGGAAGTTGTGTGAATATAATAATCTCAGTGCTTCTTTACTTCCAAAACT
GGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCCCTGCTACCATGGAGTTTCT
TGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGCCTTCACTTCAGACAGAGAA
CGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGACGGGCCAGAGCGTCCGGAGGCAG
GAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGAACAGGTCGAGCAAGCAAGTGCA
TGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTTCTTTATGGTGGCAGAGGTGGTG
GGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCTGCTCATCTCTTAATTGACCTGA
CTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAAGGCCCCCTTCCAAGCGGCTGAC
ATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTCTGTCCTTTGCATCTGGGTGGTG
ACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTATCCTGATTACCAGATCCAAGCAG
GCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACATTGTACTAACTCTGATTTTGCA
CCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAATGCCAGCGTTCGAGCGGCCTTT
GTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTAATTAGTGCTCTCATTATCTACT
TTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTATCTCTTCCGTCTTGGCTTTGGC
CAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCATGGAAGGTGTTCCAAAGGGCCTG
AGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGCGTGATCTCCGTGCACAATCTAC
ACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTCATGTTGCTACAGCTGCGAGCCA
GGACAGCCAGTCTGTGCGGACAGGAATTGCTTGCGCTCTCAGCAGTAGCTTTGATCTGCACTCT
CTTACCATTCAGATCGAATCTGCGGCAGATCAGGACCCCAGCTGCCTTCTCTGTGAAGACCCAC
AGGACTAGCTCGCTCACTGTCAGCTTCCAGTGTTTCCTAGGCCATGATAAACTGCAGCAAAGTC
TCTGCAATGCACAATTAAGCAACCAGCAGAACAGATTTGAGAAAATCATGACAATGCACTGTGC
ACGCTCTTCCATTGTGTTTGTCTCCATCCACCATGAATGAGGATGCATGGGCTTCATCAGCGTC
TTGGATTACATACTTAATCAGTAGTCGTGCTCAATGATAGTATACATAGATTATTCCTAACTGG
GGTTGAAATAGCAGATGTTGGCCACCATAGGTAATGAATGACTCACTTCCCTACAGTAGTGGGT
ACAGCTGAATTCAGGAATGCCTTTGTAGGGATCCACAGCAGGAGAAACAAATATTTGAAGAGGA
TCTCGAGGCTTGGGGATTTGACTCTTGTGCCATCCTCAGTGAAATCTCCATTATTTGTGAAACA
GTGAACCCCCCTTTTTATCTTGCATGTAAATTACGCTGTGAAGGATTGAATTATACTTTAATGC
TATGTGCAAAGGGTATGGAAAGTGGGAAAAATTTCTGAAATTGCTAACTTTTGAATGTTTTCAT
AAAGTAGAATTTAATAATGGAAGAAAACGAGGAGATGGCTTTTCTCCAGGTCACACACAAGGAA
ATTTAGTTTAAGAATTAAGATAACTCTCAAATTTTGCACACTATTCATGAATCACCATCATTCA
ATTGCTGTACTTTATTTCCCAACAAAATAACTTTTAGAATGTCAACTTATTACTATTTTTACTA
GGTAGACAGAACATAAAAATCAAAGAGGATCAGTAATTTTTAAAGTGTCATTTAGTCACAATTT
TGATGCTAGACTTGGGAAGAGGGCAGGGGAAGAGCTTTTTTTATTTCTGTAACTGAATTATACT
GGGTCATTAAAAAGGAAACAGAACTTTATATAGCTCATGGCTCTGAAGGCTGGGAGTCTGTATG
CGAGTGGCTGCTGCATGGGATGGTAATGGATGTGTGTAGAATCCCTAGGCAGAGCAGAGCATCA
TACGATGACAGGGACAAACATCTTGGCTTGCTTTTCTTCTTCATATAAAGCCACATTTTCACTG
AATTAGGTCTCTGTGTTTGTGTTCCTTTTGAACATTACCTCCCAGTGGTTTTATCCGCCCAAAC
CCAGGTTTCTAGTCTCTCAAGAGTCCACCAGGGGCATTAAATTTCAACATTAGTTTTAGTGGGG
TTGTTTAAACTGTTATCAGTGGACGGAGGTAACGTTAACACCGGCACAAATCGTGCTATTTTTC
TTGGGTTGGGGAGACATACACTATAGAGATAAAAACAACTGAGAAGTACTTTAAGAACTAGCCA
ATAATCTGAAGTAAGAGAGGCTGTGAGACTAAGGCAGGTCCATGAAGAATTTCTCAAAGAAAAC
CAAATTTGAAGGGAACAACAACAATAACAACAACAAATGTGTGTTAGCCAGATGGAATGTAGGA
GGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAG
GAGGAGCCAGATGGAATGTAGGAGAAGGCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTA
GGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATG
TAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAA
TGTAGGAGGAGGCAGGATGGGATGTAGGAGGAGCCAGGATCTATAAGAACCAAACCAGGTTGAA
ATCCATGCCACAAGAAGGTGCCCGCCTTTGACACTGCCTGGTCAGGGCAGGCTGGATAGCCCAC
AGACTTAAGATAGAACTAAACATGACTGGCAAATAAAAAAAGTCCTCGATGAAATGAAAACACA
CGGTTGCCACCCACATTAGAATAAAAACTAAACTCAGCATGTGTTGGTCCATTGCTTTAGTGAG
CAGATCACCCTCTTGATCAAGAGTAAAGTTTTGCCTTGTTGCAAGAAACTTGA

hide sequence

RefSeq Acc Id:

XM_008765500 ⟹ XP_008763722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	85,482,173 - 85,517,255 (+)	NCBI
mRatBN7.2	7	83,592,302 - 83,627,786 (+)	NCBI
Rnor_6.0	7	91,833,225 - 91,869,329 (+)	NCBI

Sequence:

show sequence

CTTCTTTACTTCCAAAACTGGACAGCAGGTCATATATCAAAAACAACAGTGTCAGCTCCTGTCC
CTGCTACCATGGAGTTTCTTGAGAGGACTTACCTTGTGAATGATCAAGCCACCAAGATGTATGC
CTTCACTTCAGACAGCAGAGAACGTGGACAGAAGCCTGTGAATAAAGATCAGTGTCCTGGAGAC
GGGCCAGAGCGTCCGGAGGCAGGAGCCATCTATCACTGCCACAACAGCTTCAAGGCCACAGGGA
ACAGGTCGAGCAAGCAAGTGCATGCCAAGTGGAGACTCTGTGCTGCTTCAGCAATATGCTTCTT
CTTTATGGTGGCAGAGGTGGTGGGTGGACATGTTGCTGGGAGTCTGGCGGTCCTCACTGATGCT
GCTCATCTCTTAATTGACCTGACTAGTTTCCTGCTCAGTCTCTTTTCTTTGTGGTTATCTTCAA
GGCCCCCTTCCAAGCGGCTGACATTTGGGTGGTATCGAGCAGAGATCCTCGGTGCCCTGCTGTC
TGTCCTTTGCATCTGGGTGGTGACTGGTGTGCTGGTGTACCTTGCCTGTGAGCGCCTCTTGTAT
CCTGATTACCAGATCCAAGCAGGCATCATGATCACTGTTTCAGGCTGTGCAGTGGCAGCCAACA
TTGTACTAACTCTGATTTTGCACCAACGGCATCTTGGCCACAACCACAAGGATGCACAAGCTAA
TGCCAGCGTTCGAGCGGCCTTTGTGCATGCCCTGGGGGATGTGTTTCAGAGCACCAGTGTGCTA
ATTAGTGCTCTCATTATCTACTTTAAGCCCGACTACAAAATGGCTGATCCAGTGTGCACATTTA
TCTCTTCCGTCTTGGCTTTGGCCAGCACCGTCATGATCTTAAAAGACTTCTCCATCTTACTCAT
GGAAGGTGTTCCAAAGGGCCTGAGTTACAACAGTGTGAAAGAACTCCTCCTCACAGTCGATGGC
GTGATCTCCGTGCACAATCTACACATCTGGTCGCTGACAGTGAACCAAGTGATTCTCTCTGTTC
ATGTTGCTACAGCTGCGAGCCAGGACAGCCAGTCTGTGCGGACAGGAATTGCTTGCGCTCTCAG
CAGTAGCTTTGATCTGCACTCTCTTACCATTCAGATCGAATCTGCGGCAGATCAGGACCCCAGC
TGCCTTCTCTGTGAAGACCCACAGGACTAGCTCGCTCACTGTCAGCTTCCAGTGTTTCCTAGGC
CATGATAAACTGCAGCAAAGTCTCTGCAATGCACAATTAAGCAACCAGCAGAACAGATTTGAGA
AAATCATGACAATGCACTGTGCACGCTCTTCCATTGTGTTTGTCTCCATCCACCATGAATGAGG
ATGCATGGGCTTCATCAGCGTCTTGGATTACATACTTAATCAGTAGTCGTGCTCAATGATAGTA
TACATAGATTATTCCTAACTGGGGTTGAAATAGCAGATGTTGGCCACCATAGGTAATGAATGAC
TCACTTCCCTACAGTAGTGGGTACAGCTGAATTCAGGAATGCCTTTGTAGGGATCCACAGCAGG
AGAAACAAATATTTGAAGAGGATCTCGAGGCTTGGGGATTTGACTCTTGTGCCATCCTCAGTGA
AATCTCCATTATTTGTGAAACAGTGAACCCCCCTTTTTATCTTGCATGTAAATTACGCTGTGAA
GGATTGAATTATACTTTAATGCTATGTGCAAAGGGTATGGAAAGTGGGAAAAATTTCTGAAATT
GCTAACTTTTGAATGTTTTCATAAAGTAGAATTTAATAATGGAAGAAAACGAGGAGATGGCTTT
TCTCCAGGTCACACACAAGGAAATTTAGTTTAAGAATTAAGATAACTCTCAAATTTTGCACACT
ATTCATGAATCACCATCATTCAATTGCTGTACTTTATTTCCCAACAAAATAACTTTTAGAATGT
CAACTTATTACTATTTTTACTAGGTAGACAGAACATAAAAATCAAAGAGGATCAGTAATTTTTA
AAGTGTCATTTAGTCACAATTTTGATGCTAGACTTGGGAAGAGGGCAGGGGAAGAGCTTTTTTT
ATTTCTGTAACTGAATTATACTGGGTCATTAAAAAGGAAACAGAACTTTATATAGCTCATGGCT
CTGAAGGCTGGGAGTCTGTATGCGAGTGGCTGCTGCATGGGATGGTAATGGATGTGTGTAGAAT
CCCTAGGCAGAGCAGAGCATCATACGATGACAGGGACAAACATCTTGGCTTGCTTTTCTTCTTC
ATATAAAGCCACATTTTCACTGAATTAGGTCTCTGTGTTTGTGTTCCTTTTGAACATTACCTCC
CAGTGGTTTTATCCGCCCAAACCCAGGTTTCTAGTCTCTCAAGAGTCCACCAGGGGCATTAAAT
TTCAACATTAGTTTTAGTGGGGTTGTTTAAACTGTTATCAGTGGACGGAGGTAACGTTAACACC
GGCACAAATCGTGCTATTTTTCTTGGGTTGGGGAGACATACACTATAGAGATAAAAACAACTGA
GAAGTACTTTAAGAACTAGCCAATAATCTGAAGTAAGAGAGGCTGTGAGACTAAGGCAGGTCCA
TGAAGAATTTCTCAAAGAAAACCAAATTTGAAGGGAACAACAACAATAACAACAACAAATGTGT
GTTAGCCAGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAG
GAGGAGCCAGGATGGAATGTAGGAGGAGCCAGATGGAATGTAGGAGAAGGCAGGATGGAATGTA
GGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATG
TAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGCCAGGATGGAA
TGTAGGAGGAGCCAGGATGGAATGTAGGAGGAGGCAGGATGGGATGTAGGAGGAGCCAGGATCT
ATAAGAACCAAACCAGGTTGAAATCCATGCCACAAGAAGGTGCCCGCCTTTGACACTGCCTGGT
CAGGGCAGGCTGGATAGCCCACAGACTTAAGATAGAACTAAACATGACTGGCAAATAAAAAAAG
TCCTCGATGAAATGAAAACACACGGTTGCCACCCACATTAGAATAAAAACTAAACTCAGCATGT
GTTGGTCCATTGCTTTAGTGAGCAGATCACCCTCTTGATCAAGAGTAAAGTTTTGCCTTGTTGC
AAGAAACTTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001124010	(Get FASTA)	NCBI Sequence Viewer
	XP_006241707	(Get FASTA)	NCBI Sequence Viewer
	XP_008763722	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16273	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006410
	ENSRNOP00000006410.7
GenBank Protein	P0CE46	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001124010 ⟸ NM_001130538

- UniProtKB:

P0CE46 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSS
KQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPS
KRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLT
LILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSV
LALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVAT
GQ

hide sequence

RefSeq Acc Id:

XP_006241707 ⟸ XM_006241645

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEFLERTYLVNDQATKMYAFTSDRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRSS
KQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPPS
KRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVLT
LILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISSV
LALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVAT
AASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD

hide sequence

RefSeq Acc Id:

XP_008763722 ⟸ XM_008765500

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEFLERTYLVNDQATKMYAFTSDSRERGQKPVNKDQCPGDGPERPEAGAIYHCHNSFKATGNRS
SKQVHAKWRLCAASAICFFFMVAEVVGGHVAGSLAVLTDAAHLLIDLTSFLLSLFSLWLSSRPP
SKRLTFGWYRAEILGALLSVLCIWVVTGVLVYLACERLLYPDYQIQAGIMITVSGCAVAANIVL
TLILHQRHLGHNHKDAQANASVRAAFVHALGDVFQSTSVLISALIIYFKPDYKMADPVCTFISS
VLALASTVMILKDFSILLMEGVPKGLSYNSVKELLLTVDGVISVHNLHIWSLTVNQVILSVHVA
TAASQDSQSVRTGIACALSSSFDLHSLTIQIESAADQDPSCLLCEDPQD

hide sequence

Ensembl Acc Id:

ENSRNOP00000006410 ⟸ ENSRNOT00000006410

Ensembl Acc Id:

ENSRNOP00000069455 ⟸ ENSRNOT00000079792

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0CE46-F1-model_v2	AlphaFold	P0CE46	1-368	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308282	AgrOrtholog
BioCyc Gene	G2FUF-33421	BioCyc
Ensembl Genes	ENSRNOG00000004747	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006410	ENTREZGENE
	ENSRNOT00000006410.7	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1510.10	UniProtKB/Swiss-Prot
InterPro	Cation_efflux	UniProtKB/Swiss-Prot
	Cation_efflux_CTD_sf	UniProtKB/Swiss-Prot
	Cation_efflux_TMD_sf	UniProtKB/Swiss-Prot
	CDF/SLC30A	UniProtKB/Swiss-Prot
KEGG Report	rno:299903	UniProtKB/Swiss-Prot
NCBI Gene	299903	ENTREZGENE
PANTHER	CATION EFFLUX PROTEIN/ ZINC TRANSPORTER	UniProtKB/Swiss-Prot
	PTHR11562:SF37	UniProtKB/Swiss-Prot
Pfam	Cation_efflux	UniProtKB/Swiss-Prot
PhenoGen	Slc30a8	PhenoGen
RatGTEx	ENSRNOG00000004747	RatGTEx
Superfamily-SCOP	SSF160240	UniProtKB/Swiss-Prot
	SSF161111	UniProtKB/Swiss-Prot
UniProt	P0CE46	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Slc30a8	solute carrier family 30 (zinc transporter), member 8	Slc30a8_predicted	solute carrier family 30 (zinc transporter), member 8 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Slc30a8_predicted	solute carrier family 30 (zinc transporter), member 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM