Pilrb2l3 (paired immunoglobin like type 2 receptor beta 2 like 3) - Rat Genome Database

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Gene: Pilrb2l3 (paired immunoglobin like type 2 receptor beta 2 like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Pilrb2l3 (Ensembl: RGD1563400)
Name: paired immunoglobin like type 2 receptor beta 2 like 3 (Ensembl:similar to paired immunoglobin-like type 2 receptor beta)
RGD ID: 1561730
Description: Predicted to be located in cell periphery and membrane. Orthologous to human PILRA (paired immunoglobin like type 2 receptor alpha); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC498169; paired immunoglobulin-like type 2 receptor beta; paired immunoglobulin-like type 2 receptor beta-2; RGD1561730; similar to cell surface receptor FDFACT
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81223,125,397 - 23,132,038 (-)NCBIGRCr8
mRatBN7.21218,210,535 - 18,216,471 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,210,535 - 18,216,443 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01220,592,922 - 20,660,658 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,592,216 - 20,660,304 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,696,309 - 22,702,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,433,500 - 20,442,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1219,811,760 - 19,818,206 (+)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell periphery  (IEA)
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Pilrb2l3
72 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 33 97 79 78 47 25 47 6 182 81 77 37 52 31

Sequence


Ensembl Acc Id: ENSRNOT00000091323   ⟹   ENSRNOP00000074039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1220,592,216 - 20,660,304 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098725   ⟹   ENSRNOP00000090856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,210,535 - 18,216,443 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119260   ⟹   ENSRNOP00000090991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,210,535 - 18,216,443 (-)Ensembl
RefSeq Acc Id: XM_006249057   ⟹   XP_006249119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81223,125,405 - 23,131,921 (-)NCBI
mRatBN7.21218,210,535 - 18,216,465 (-)NCBI
Rnor_6.01220,654,206 - 20,660,658 (-)NCBI
Rnor_5.01222,696,309 - 22,702,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769088   ⟹   XP_008767310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81223,125,397 - 23,132,038 (-)NCBI
mRatBN7.21218,210,535 - 18,216,469 (-)NCBI
Rnor_6.01220,654,206 - 20,660,658 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090015   ⟹   XP_038945943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81223,125,811 - 23,131,916 (-)NCBI
mRatBN7.21218,210,535 - 18,216,460 (-)NCBI
Protein Sequences
Protein RefSeqs XP_006249119 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767310 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945943 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000082370.1
  ENSRNOP00000090856.1
  ENSRNOP00000090991.1
RefSeq Acc Id: XP_006249119   ⟸   XM_006249057
- Peptide Label: isoform X2
- UniProtKB: A0A8I6APL2 (UniProtKB/TrEMBL),   A0A8I5ZX13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008767310   ⟸   XM_008769088
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ABT8 (UniProtKB/TrEMBL),   A0A8I5ZX13 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074039   ⟸   ENSRNOT00000091323
RefSeq Acc Id: XP_038945943   ⟸   XM_039090015
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000090991   ⟸   ENSRNOT00000119260
Ensembl Acc Id: ENSRNOP00000090856   ⟸   ENSRNOT00000098725

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K729-F1-model_v2 AlphaFold A0A0G2K729 1-217 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561730 AgrOrtholog
BioCyc Gene G2FUF-19750 BioCyc
Ensembl Genes ENSRNOG00000048881 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000057141 Ensembl
  ENSRNOG00000063533 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098725.1 UniProtKB/TrEMBL
  ENSRNOT00000101564.1 UniProtKB/TrEMBL
  ENSRNOT00000119260.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Immunoregulatory_rcpt-like UniProtKB/TrEMBL
KEGG Report rno:498169 UniProtKB/TrEMBL
NCBI Gene 498169 ENTREZGENE
PANTHER PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR UniProtKB/TrEMBL
  PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA-RELATED UniProtKB/TrEMBL
PhenoGen Pilrb2l3 PhenoGen
RatGTEx ENSRNOG00000048881 RatGTEx
  ENSRNOG00000057141 RatGTEx
  ENSRNOG00000063533 RatGTEx
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZX13 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APL2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Pilrb2l3  paired immunoglobin like type 2 receptor beta 2 like 3  RGD1561730  similar to cell surface receptor FDFACT  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1561730  similar to cell surface receptor FDFACT   RGD1561730_predicted  similar to cell surface receptor FDFACT (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561730_predicted  similar to cell surface receptor FDFACT (predicted)  LOC498169  similar to cell surface receptor FDFACT  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498169  similar to cell surface receptor FDFACT      Symbol and Name status set to provisional 70820 PROVISIONAL