Mbd6 (methyl-CpG binding domain protein 6) - Rat Genome Database

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Gene: Mbd6 (methyl-CpG binding domain protein 6) Rattus norvegicus
Analyze
Symbol: Mbd6
Name: methyl-CpG binding domain protein 6
RGD ID: 1311050
Description: Predicted to enable chromatin binding activity. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in chromocenter and nucleus. Human ortholog(s) of this gene implicated in autism spectrum disorder. Orthologous to human MBD6 (methyl-CpG binding domain protein 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102553371; LOC362892; methyl-CpG-binding domain protein 6; WAS/WASL-interacting protein family member 1-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,992,877 - 65,001,274 (-)NCBIGRCr8
mRatBN7.2763,107,562 - 63,115,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,107,562 - 63,113,274 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,996,836 - 65,002,548 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,199,256 - 67,204,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,000,607 - 67,006,319 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,571,435 - 70,580,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,571,435 - 70,577,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,745,585 - 70,752,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,239,304 - 67,245,037 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,260,033 - 67,265,767 (-)NCBI
Celera760,248,101 - 60,253,813 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromocenter  (IBA,ISO)
fibrillar center  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1. Cukier HN, etal., Autism Res. 2012 Dec;5(6):385-97. doi: 10.1002/aur.1251. Epub 2012 Oct 10.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:20700456   PMID:30361391  


Genomics

Comparative Map Data
Mbd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,992,877 - 65,001,274 (-)NCBIGRCr8
mRatBN7.2763,107,562 - 63,115,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,107,562 - 63,113,274 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,996,836 - 65,002,548 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,199,256 - 67,204,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,000,607 - 67,006,319 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,571,435 - 70,580,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,571,435 - 70,577,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,745,585 - 70,752,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,239,304 - 67,245,037 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,260,033 - 67,265,767 (-)NCBI
Celera760,248,101 - 60,253,813 (-)NCBICelera
Cytogenetic Map7q22NCBI
MBD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,520,715 - 57,531,545 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,520,710 - 57,530,148 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,916,607 - 57,923,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,202,926 - 56,210,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,202,925 - 56,210,198NCBI
Celera1257,572,491 - 57,579,763 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,932,323 - 54,961,829 (+)NCBIHuRef
CHM1_11257,884,526 - 57,891,756 (+)NCBICHM1_1
T2T-CHM13v2.01257,488,889 - 57,498,388 (+)NCBIT2T-CHM13v2.0
Mbd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,117,825 - 127,126,738 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,117,825 - 127,124,887 (-)EnsemblGRCm39 Ensembl
GRCm3810127,281,956 - 127,290,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,281,956 - 127,289,018 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,719,012 - 126,725,827 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,684,905 - 126,691,720 (-)NCBIMGSCv36mm8
Celera10129,674,397 - 129,680,132 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Mbd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,238,570 - 5,247,711 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,238,570 - 5,247,711 (+)NCBIChiLan1.0ChiLan1.0
MBD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,810,961 - 36,818,440 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,807,732 - 36,817,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,655,461 - 31,664,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,655,461 - 31,664,638 (-)Ensemblpanpan1.1panPan2
MBD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,611,462 - 1,620,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,613,643 - 1,619,745 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,674,704 - 1,683,709 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,620,536 - 1,629,548 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,621,929 - 1,629,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,598,546 - 1,607,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,840,434 - 1,849,437 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,965,429 - 1,974,435 (+)NCBIUU_Cfam_GSD_1.0
Mbd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,791,437 - 22,799,126 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,790,220 - 22,799,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,754,021 - 24,761,374 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MBD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,431,423 - 53,438,719 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,432,903 - 53,437,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,524,292 - 192,532,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,428,782 - 10,437,777 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,428,782 - 10,437,992 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mbd6
13 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:509
Count of miRNA genes:223
Interacting mature miRNAs:272
Transcripts:ENSRNOT00000008854
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat

Markers in Region
D10Wsu93e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,661 - 63,107,912 (+)MAPPERmRatBN7.2
Rnor_6.0770,571,535 - 70,571,785NCBIRnor6.0
Rnor_5.0770,745,685 - 70,745,935UniSTSRnor5.0
RGSC_v3.4767,239,405 - 67,239,655UniSTSRGSC3.4
Celera760,248,201 - 60,248,451UniSTS
Cytogenetic Map7q22UniSTS
RH127945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,133 - 63,107,316 (+)MAPPERmRatBN7.2
Rnor_6.0770,571,007 - 70,571,189NCBIRnor6.0
Rnor_5.0770,745,157 - 70,745,339UniSTSRnor5.0
RGSC_v3.4767,238,876 - 67,239,058UniSTSRGSC3.4
Celera760,247,673 - 60,247,855UniSTS
Cytogenetic Map7q22UniSTS
C87049  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,063 - 63,107,319 (+)MAPPERmRatBN7.2
Rnor_6.0770,570,937 - 70,571,192NCBIRnor6.0
Rnor_5.0770,745,087 - 70,745,342UniSTSRnor5.0
RGSC_v3.4767,238,806 - 67,239,061UniSTSRGSC3.4
Celera760,247,603 - 60,247,858UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_355570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI296976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB777944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY314707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000008854   ⟹   ENSRNOP00000008854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,107,562 - 63,113,274 (-)Ensembl
Rnor_6.0 Ensembl770,571,435 - 70,577,147 (-)Ensembl
RefSeq Acc Id: NM_001170566   ⟹   NP_001164037
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,998,589 (-)NCBI
mRatBN7.2763,107,562 - 63,113,274 (-)NCBI
Rnor_6.0770,571,435 - 70,577,147 (-)NCBI
Rnor_5.0770,745,585 - 70,752,317 (-)NCBI
Celera760,248,101 - 60,253,813 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241463   ⟹   XP_006241525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,525 (-)NCBI
mRatBN7.2763,107,562 - 63,114,208 (-)NCBI
Rnor_6.0770,571,435 - 70,578,118 (-)NCBI
Rnor_5.0770,745,585 - 70,752,317 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765404   ⟹   XP_008763626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,428 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765405   ⟹   XP_008763627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,525 (-)NCBI
mRatBN7.2763,107,562 - 63,114,208 (-)NCBI
Rnor_6.0770,571,435 - 70,578,118 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765407   ⟹   XP_008763629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,428 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594925   ⟹   XP_017450414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,430 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079488   ⟹   XP_038935416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 65,001,274 (-)NCBI
mRatBN7.2763,107,562 - 63,115,841 (-)NCBI
RefSeq Acc Id: XM_063263801   ⟹   XP_063119871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,526 (-)NCBI
RefSeq Acc Id: XM_063263802   ⟹   XP_063119872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,993,978 - 64,999,745 (-)NCBI
RefSeq Acc Id: XR_010053002
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
RefSeq Acc Id: XR_355568
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,428 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Rnor_5.0770,745,585 - 70,752,317 (-)NCBI
Sequence:
RefSeq Acc Id: XR_355569
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,428 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Rnor_5.0770,745,585 - 70,752,317 (-)NCBI
Sequence:
RefSeq Acc Id: XR_355570
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,992,877 - 64,999,745 (-)NCBI
mRatBN7.2763,107,562 - 63,114,428 (-)NCBI
Rnor_6.0770,571,435 - 70,578,471 (-)NCBI
Rnor_5.0770,745,585 - 70,752,317 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001164037   ⟸   NM_001170566
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241525   ⟸   XM_006241463
- Peptide Label: isoform X1
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763629   ⟸   XM_008765407
- Peptide Label: isoform X2
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763626   ⟸   XM_008765404
- Peptide Label: isoform X1
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763627   ⟸   XM_008765405
- Peptide Label: isoform X1
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450414   ⟸   XM_017594925
- Peptide Label: isoform X1
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008854   ⟸   ENSRNOT00000008854
RefSeq Acc Id: XP_038935416   ⟸   XM_039079488
- Peptide Label: isoform X1
- UniProtKB: D3ZCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119871   ⟸   XM_063263801
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063119872   ⟸   XM_063263802
- Peptide Label: isoform X3
Protein Domains
MBD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZCX1-F1-model_v2 AlphaFold D3ZCX1 1-1005 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311050 AgrOrtholog
BioCyc Gene G2FUF-33755 BioCyc
Ensembl Genes ENSRNOG00000006209 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008854.7 UniProtKB/TrEMBL
InterPro DNA-bd_dom UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
NCBI Gene 362892 ENTREZGENE
PANTHER METHYL-CPG-BINDING DOMAIN PROTEIN 6 UniProtKB/TrEMBL
  PTHR16112 UniProtKB/TrEMBL
PhenoGen Mbd6 PhenoGen
PROSITE MBD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006209 RatGTEx
SMART MBD UniProtKB/TrEMBL
Superfamily-SCOP SSF54171 UniProtKB/TrEMBL
UniProt D3ZCX1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Mbd6  methyl-CpG binding domain protein 6  LOC102553371  WAS/WASL-interacting protein family member 1-like  Data merged from RGD:7670708 737654 PROVISIONAL
2013-12-18 LOC102553371  WAS/WASL-interacting protein family member 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Mbd6  methyl-CpG binding domain protein 6   Mbd6_predicted  methyl-CpG binding domain protein 6 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mbd6_predicted  methyl-CpG binding domain protein 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED