MBD6 (methyl-CpG binding domain protein 6) - Rat Genome Database

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Gene: MBD6 (methyl-CpG binding domain protein 6) Pan paniscus
Analyze
Symbol: MBD6
Name: methyl-CpG binding domain protein 6
RGD ID: 11928189
Description: ENCODES a protein that exhibits DNA binding (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); familial melanoma (ortholog); FOUND IN chromocenter (inferred); fibrillar center (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methyl-CpG-binding domain protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,810,961 - 36,818,440 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,807,732 - 36,817,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,655,461 - 31,664,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,655,461 - 31,664,638 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MBD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,810,961 - 36,818,440 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,807,732 - 36,817,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,655,461 - 31,664,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,655,461 - 31,664,638 (-)Ensemblpanpan1.1panPan2
MBD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,520,715 - 57,531,545 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,520,710 - 57,530,148 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,916,607 - 57,923,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,202,926 - 56,210,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,202,925 - 56,210,198NCBI
Celera1257,572,491 - 57,579,763 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,932,323 - 54,961,829 (+)NCBIHuRef
CHM1_11257,884,526 - 57,891,756 (+)NCBICHM1_1
T2T-CHM13v2.01257,488,889 - 57,498,388 (+)NCBIT2T-CHM13v2.0
Mbd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,117,825 - 127,126,738 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,117,825 - 127,124,887 (-)EnsemblGRCm39 Ensembl
GRCm3810127,281,956 - 127,290,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,281,956 - 127,289,018 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,719,012 - 126,725,827 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,684,905 - 126,691,720 (-)NCBIMGSCv36mm8
Celera10129,674,397 - 129,680,132 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Mbd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,992,877 - 65,001,274 (-)NCBIGRCr8
mRatBN7.2763,107,562 - 63,115,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,107,562 - 63,113,274 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,996,836 - 65,002,548 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,199,256 - 67,204,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,000,607 - 67,006,319 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,571,435 - 70,580,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,571,435 - 70,577,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,745,585 - 70,752,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,239,304 - 67,245,037 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,260,033 - 67,265,767 (-)NCBI
Celera760,248,101 - 60,253,813 (-)NCBICelera
Cytogenetic Map7q22NCBI
Mbd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,238,570 - 5,247,711 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,238,570 - 5,247,711 (+)NCBIChiLan1.0ChiLan1.0
MBD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,611,462 - 1,620,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,613,643 - 1,619,745 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,674,704 - 1,683,709 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,620,536 - 1,629,548 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,621,929 - 1,629,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,598,546 - 1,607,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,840,434 - 1,849,437 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,965,429 - 1,974,435 (+)NCBIUU_Cfam_GSD_1.0
Mbd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,791,437 - 22,799,126 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,790,220 - 22,799,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,754,021 - 24,761,374 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MBD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,431,423 - 53,438,719 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,432,903 - 53,437,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,524,292 - 192,532,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,428,782 - 10,437,777 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,428,782 - 10,437,992 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000060480   ⟹   ENSPPAP00000037580
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1231,655,461 - 31,664,638 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060490   ⟹   ENSPPAP00000037590
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1231,655,461 - 31,662,353 (-)Ensembl
RefSeq Acc Id: XM_034935569   ⟹   XP_034791460
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,440 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,128 (-)NCBI
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBI
RefSeq Acc Id: XM_034935570   ⟹   XP_034791461
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,428 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,164 (-)NCBI
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBI
RefSeq Acc Id: XR_004665652
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,396 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,128 (-)NCBI
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBI
RefSeq Acc Id: XR_004665653
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,396 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,128 (-)NCBI
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBI
RefSeq Acc Id: XR_004665654
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,396 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,128 (-)NCBI
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBI
RefSeq Acc Id: XR_008620393
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,399 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,127 (-)NCBI
RefSeq Acc Id: XR_008620394
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,399 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,127 (-)NCBI
RefSeq Acc Id: XR_008620395
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,810,961 - 36,818,399 (-)NCBI
NHGRI_mPanPan11236,807,732 - 36,815,127 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034791460 (Get FASTA)   NCBI Sequence Viewer  
  XP_034791461 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037580.1
  ENSPPAP00000037590.1
Reference Protein Sequences
RefSeq Acc Id: XP_034791461   ⟸   XM_034935570
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C6L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034791460   ⟸   XM_034935569
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000037590   ⟸   ENSPPAT00000060490
RefSeq Acc Id: ENSPPAP00000037580   ⟸   ENSPPAT00000060480
Protein Domains
MBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041542 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060480.1 UniProtKB/TrEMBL
  ENSPPAT00000060490.1 UniProtKB/TrEMBL
InterPro DNA-bd_dom_sf UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
NCBI Gene MBD6 ENTREZGENE
PANTHER METHYL-CPG-BINDING DOMAIN PROTEIN 6 UniProtKB/TrEMBL
  PTHR16112 UniProtKB/TrEMBL
PROSITE MBD UniProtKB/TrEMBL
SMART MBD UniProtKB/TrEMBL
Superfamily-SCOP SSF54171 UniProtKB/TrEMBL
UniProt A0A2R9C6L7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C6N4_PANPA UniProtKB/TrEMBL