SHH (sonic hedgehog signaling molecule) - Rat Genome Database

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Gene: SHH (sonic hedgehog signaling molecule) Canis lupus familiaris
Analyze
Symbol: SHH
Name: sonic hedgehog signaling molecule
RGD ID: 12429705
Description: ENCODES a protein that exhibits hydrolase activity (ortholog); INVOLVED IN alpha-tubulin acetylation (ortholog); anatomical structure formation involved in morphogenesis (ortholog); androgen metabolic process (ortholog); PARTICIPATES IN altered Hedgehog signaling pathway; forkhead class A signaling pathway; glypican signaling pathway; ASSOCIATED WITH acrocallosal syndrome (ortholog); Anorectal Malformations (ortholog); atrioventricular septal defect (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sonic hedgehog; sonic hedgehog homolog; sonic hedgehog protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,650,553 - 18,663,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,484,809 - 18,662,903 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1619,286,449 - 19,295,913 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01620,382,879 - 20,392,367 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1620,382,707 - 20,392,037 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,753,210 - 18,762,671 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01619,333,131 - 19,342,583 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01619,386,812 - 19,396,258 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
acrocallosal syndrome  (ISO)
Anorectal Malformations  (ISO)
atrioventricular septal defect  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
basal cell carcinoma  (ISO)
biliary atresia  (ISO)
brachydactyly type A1  (ISO)
chronic kidney disease  (ISO)
cleft palate  (ISO)
colorectal cancer  (ISO)
Congenital Limb Deformities  (ISO)
demyelinating disease  (ISO)
Desbuquois dysplasia  (ISO)
esophageal atresia/tracheoesophageal fistula  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Eye Abnormalities  (ISO)
Failure to Thrive  (ISO)
Fluoride Poisoning  (ISO)
focal segmental glomerulosclerosis  (ISO)
gastrointestinal stromal tumor  (ISO)
genetic disease  (ISO)
hepatocellular carcinoma  (ISO)
Hirschsprung's disease  (ISO)
holoprosencephaly  (ISO)
holoprosencephaly 3  (ISO)
Hyperoxic Lung Injury  (ISO)
hypoplastic or aplastic tibia with polydactyly  (ISO)
hypothyroidism  (ISO)
IgA glomerulonephritis  (ISO)
Isolated Microphthalmia with Coloboma 5  (ISO)
Kidney Reperfusion Injury  (ISO)
membranous glomerulonephritis  (ISO)
microphthalmia  (ISO)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
neurodevelopmental disorder with dysmorphic facies and distal limb anomalies  (ISO)
nevoid basal cell carcinoma syndrome  (ISO)
ocular hypertension  (ISO)
Parkinsonism  (ISO)
Partial Agenesis of Corpus Callosum  (ISO)
Patterson Stevenson Syndrome  (ISO)
Peripheral Nerve Injuries  (ISO)
Persistent Cloaca  (ISO)
polydactyly  (ISO)
pre-malignant neoplasm  (ISO)
preaxial polydactyly II  (ISO)
primary progressive multiple sclerosis  (ISO)
Schizencephaly  (ISO)
secondary Parkinson disease  (ISO)
septooptic dysplasia  (ISO)
solitary median maxillary central incisor  (ISO)
Spinal Cord Injuries  (ISO)
stomach cancer  (ISO)
Subarachnoid Hemorrhage  (ISO)
syndactyly type 4  (ISO)
temporal lobe epilepsy  (ISO)
Thakker-Donnai Syndrome  (ISO)
transient cerebral ischemia  (ISO)
ureteral obstruction  (ISO)
VACTERL association  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-tubulin acetylation  (ISO)
anatomical structure formation involved in morphogenesis  (ISO)
androgen metabolic process  (ISO)
angiogenesis  (ISO)
animal organ development  (IEA)
animal organ formation  (ISO)
anterior/posterior pattern specification  (ISO)
apoptotic signaling pathway  (IEA)
artery development  (ISO)
axon guidance  (ISO)
Bergmann glial cell differentiation  (ISO)
blood coagulation  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
branching involved in prostate gland morphogenesis  (ISO)
branching involved in salivary gland morphogenesis  (ISO)
branching involved in ureteric bud morphogenesis  (ISO)
branching morphogenesis of an epithelial tube  (ISO)
bud outgrowth involved in lung branching  (ISO)
camera-type eye development  (ISO)
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment  (IEA)
cell development  (IEA,ISO)
cell fate commitment  (IEA,ISO)
cell fate specification  (IBA,ISO)
cell population proliferation  (ISO)
cell proliferation in external granule layer  (ISO)
cell-cell signaling  (IEA,ISO)
cellular response to L-glutamate  (ISO)
cellular response to lithium ion  (ISO)
central nervous system development  (IEA,ISO)
cerebellar granule cell precursor proliferation  (IEA)
commissural neuron axon guidance  (ISO)
determination of left/right asymmetry in lateral mesoderm  (IEA)
determination of left/right symmetry  (ISO)
developmental growth  (ISO)
digestive tract mesoderm development  (ISO)
digestive tract morphogenesis  (ISO)
dorsal/ventral neural tube patterning  (ISO)
dorsal/ventral pattern formation  (ISO)
ectoderm development  (ISO)
embryonic digestive tract morphogenesis  (ISO)
embryonic digit morphogenesis  (IEA,ISO)
embryonic foregut morphogenesis  (ISO)
embryonic forelimb morphogenesis  (ISO)
embryonic hindlimb morphogenesis  (ISO)
embryonic limb morphogenesis  (ISO)
embryonic morphogenesis  (ISO)
embryonic organ development  (ISO)
embryonic skeletal system development  (ISO)
endocytosis  (ISO)
epithelial cell proliferation involved in salivary gland morphogenesis  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
epithelial-mesenchymal cell signaling  (ISO)
establishment of cell polarity  (ISO)
forebrain development  (ISO)
forebrain regionalization  (ISO)
formation of anatomical boundary  (ISO)
fungiform papilla development  (ISO)
fungiform papilla formation  (ISO)
fungiform papilla morphogenesis  (ISO)
gene expression  (ISO)
hair follicle development  (ISO)
hair follicle morphogenesis  (ISO)
heart development  (ISO)
heart looping  (ISO)
hindbrain development  (ISO)
hindgut morphogenesis  (ISO)
inner ear development  (ISO)
intein-mediated protein splicing  (IEA)
intermediate filament organization  (ISO)
kidney development  (ISO)
lateral motor column neuron differentiation  (ISO)
left lung development  (ISO)
limb bud formation  (ISO)
limb development  (ISO)
liver regeneration  (ISO)
lung development  (ISO)
lung epithelium development  (ISO)
lung lobe morphogenesis  (ISO)
lung morphogenesis  (ISO)
lung-associated mesenchyme development  (ISO)
lymphoid progenitor cell differentiation  (IEA)
male genitalia development  (ISO)
male genitalia morphogenesis  (ISO)
mesenchymal cell proliferation  (ISO)
mesenchymal cell proliferation involved in lung development  (ISO)
mesenchymal smoothened signaling pathway involved in prostate gland development  (ISO)
metanephric collecting duct development  (IEA)
metanephric mesenchymal cell proliferation involved in metanephros development  (IEA)
metanephros development  (IEA)
midbrain development  (ISO)
myoblast differentiation  (ISO)
myotube differentiation  (ISO)
negative regulation of alpha-beta T cell differentiation  (ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cellular process  (ISO)
negative regulation of cholesterol efflux  (IEA)
negative regulation of dopaminergic neuron differentiation  (IEA)
negative regulation of gene expression  (IEA)
negative regulation of kidney smooth muscle cell differentiation  (IEA)
negative regulation of mesenchymal cell apoptotic process  (ISO)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
negative regulation of protein catabolic process  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription elongation by RNA polymerase II  (ISO)
negative regulation of ureter smooth muscle cell differentiation  (IEA)
negative regulation of Wnt signaling pathway  (ISO)
negative thymic T cell selection  (IEA)
neural crest cell migration  (ISO)
neural tube formation  (ISO)
neuroblast proliferation  (ISO)
neuron differentiation  (IEA)
neuron fate commitment  (ISO)
odontogenesis  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
oligodendrocyte development  (ISO)
oligodendrocyte differentiation  (IBA,ISO)
osteoblast development  (ISO)
pancreas development  (ISO)
pattern specification process  (IEA,ISO)
polarity specification of anterior/posterior axis  (IEA)
positive regulation of alpha-beta T cell differentiation  (IEA)
positive regulation of cell differentiation  (ISO)
positive regulation of cell division  (IEA)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of cerebellar granule cell precursor proliferation  (ISO)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of endothelial cell chemotaxis  (ISO)
positive regulation of epithelial cell proliferation involved in prostate gland development  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of immature T cell proliferation in thymus  (IEA)
positive regulation of kidney smooth muscle cell differentiation  (IEA)
positive regulation of mesenchymal cell proliferation  (ISO)
positive regulation of mesenchymal cell proliferation involved in ureter development  (IEA)
positive regulation of neuroblast proliferation  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of neurotrophin production  (ISO)
positive regulation of oligodendrocyte differentiation  (ISO)
positive regulation of oligodendrocyte progenitor proliferation  (ISO)
positive regulation of penile erection  (ISO)
positive regulation of photoreceptor cell differentiation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of sclerotome development  (IEA)
positive regulation of skeletal muscle cell proliferation  (ISO)
positive regulation of skeletal muscle tissue development  (ISO)
positive regulation of smoothened signaling pathway  (IEA)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of striated muscle cell differentiation  (ISO)
positive regulation of T cell differentiation in thymus  (IEA)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of ureter smooth muscle cell differentiation  (IEA)
positive regulation of Wnt signaling pathway  (ISO)
positive thymic T cell selection  (IEA)
primary prostatic bud elongation  (ISO)
prostate epithelial cord elongation  (ISO)
prostate gland development  (ISO)
protein autoprocessing  (IEA)
protein localization to nucleus  (ISO)
proteolysis  (IEA)
regulation of cell population proliferation  (IEA,ISO)
regulation of developmental process  (IEA)
regulation of DNA-templated transcription  (ISO)
regulation of epithelial cell differentiation  (ISO)
regulation of epithelial cell proliferation involved in prostate gland development  (ISO)
regulation of gene expression  (IBA,ISO)
regulation of mesenchymal cell proliferation involved in prostate gland development  (ISO)
regulation of odontogenesis  (IEA)
regulation of prostatic bud formation  (ISO)
regulation of protein localization to nucleus  (IEA)
regulation of proteolysis  (ISO)
respiratory tube development  (ISO)
response to axon injury  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to retinoic acid  (ISO)
right lung development  (ISO)
roof of mouth development  (ISO)
salivary gland cavitation  (ISO)
self proteolysis  (IEA)
skin development  (ISO)
smooth muscle tissue development  (IEA)
smoothened signaling pathway  (IBA,IEA,ISO)
somite development  (IEA)
spinal cord dorsal/ventral patterning  (ISO)
spinal cord motor neuron differentiation  (ISO)
stem cell development  (IEA)
striated muscle cell differentiation  (ISO)
striated muscle tissue development  (ISO)
system development  (IEA)
T cell differentiation in thymus  (IEA)
telencephalon regionalization  (ISO)
thalamus development  (ISO)
thymus development  (IEA)
thyroid gland development  (ISO)
tissue development  (IEA)
tongue development  (ISO)
tongue morphogenesis  (ISO)
trachea development  (ISO)
trachea morphogenesis  (ISO)
tracheoesophageal septum formation  (ISO)
tube development  (IEA)
vasculature development  (ISO)
vasculogenesis  (ISO)
ventral spinal cord interneuron specification  (ISO)
zona limitans intrathalamica formation  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16687440   PMID:19194078   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SHH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,650,553 - 18,663,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,484,809 - 18,662,903 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1619,286,449 - 19,295,913 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01620,382,879 - 20,392,367 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1620,382,707 - 20,392,037 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,753,210 - 18,762,671 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01619,333,131 - 19,342,583 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01619,386,812 - 19,396,258 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
SHH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387155,799,980 - 155,812,463 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7155,799,980 - 155,812,463 (-)Ensemblhg38GRCh38
GRCh377155,592,674 - 155,605,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367155,288,319 - 155,297,728 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347155,095,033 - 155,104,443NCBI
Celera7150,021,217 - 150,030,626 (-)NCBICelera
Cytogenetic Map7q36.3NCBI
HuRef7149,327,101 - 149,336,513 (-)NCBIHuRef
CHM1_17155,604,000 - 155,613,409 (-)NCBICHM1_1
T2T-CHM13v2.07156,983,127 - 156,995,607 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27154,827,119 - 154,836,528 (-)NCBI
Shh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,661,838 - 28,672,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl528,661,813 - 28,672,254 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38528,456,840 - 28,467,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl528,456,815 - 28,467,256 (-)Ensemblmm10GRCm38
MGSCv37528,783,380 - 28,793,641 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36528,787,627 - 28,797,875 (-)NCBIMGSCv36mm8
Celera525,997,895 - 26,008,156 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map514.39NCBI
Shh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr847,687,872 - 7,697,025 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl47,687,846 - 7,697,901 (+)EnsemblGRCr8
mRatBN7.246,954,017 - 6,963,170 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl46,954,017 - 6,963,170 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx411,962,609 - 11,971,762 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.047,776,827 - 7,785,980 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,123,054 - 6,132,207 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04718,538 - 727,691 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4718,538 - 727,691 (-)Ensemblrn6Rnor6.0
Rnor_5.04711,420 - 720,573 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.442,200,504 - 2,209,657 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera43,316,537 - 3,325,690 (-)NCBICelera
RGSC_v3.142,200,503 - 2,209,657 (+)NCBI
Cytogenetic Map4q11NCBI
Shh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554918,648,150 - 8,656,791 (-)Ensembl
ChiLan1.0NW_0049554918,647,133 - 8,657,381 (-)NCBIChiLan1.0ChiLan1.0
SHH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26192,227,225 - 192,240,917 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1744,237,491 - 44,251,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07147,400,112 - 147,414,036 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17159,116,966 - 159,126,660 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7159,114,666 - 159,126,651 (-)EnsemblpanPan2panpan1.1
Shh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051182,860,455 - 2,871,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652710,033,299 - 10,042,599 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493652710,033,095 - 10,042,713 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,545,994 - 2,555,484 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1182,546,202 - 2,555,484 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2182,664,794 - 2,673,805 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SHH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121123,929,937 - 123,942,451 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21123,932,900 - 123,942,395 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607220,134,625 - 20,147,164 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,203,393 - 2,212,068 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248002,202,986 - 2,215,309 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Shh
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16157,238,760 - 157,248,931 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in SHH
133 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
3 5 4 23 22 16 6 6 6 6 28 17 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000044474   ⟹   ENSCAFP00000038369
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,653,509 - 18,662,903 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000067884   ⟹   ENSCAFP00000050657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,484,809 - 18,662,903 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000072819   ⟹   ENSCAFP00000055263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,653,337 - 18,660,684 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845023574   ⟹   ENSCAFP00845018508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1620,382,707 - 20,392,037 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845023589   ⟹   ENSCAFP00845018515
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1620,382,707 - 20,389,689 (-)Ensembl
RefSeq Acc Id: XM_038497393   ⟹   XP_038353321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11618,753,210 - 18,762,671 (-)NCBI
RefSeq Acc Id: XM_038559814   ⟹   XP_038415742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01619,386,812 - 19,396,258 (-)NCBI
RefSeq Acc Id: XM_038623817   ⟹   XP_038479745
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01619,333,131 - 19,342,583 (-)NCBI
RefSeq Acc Id: XM_038689583   ⟹   XP_038545511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01620,382,879 - 20,392,367 (-)NCBI
RefSeq Acc Id: XM_845357   ⟹   XP_850450
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11618,650,553 - 18,663,571 (-)NCBI
Dog10K_Boxer_Tasha1619,286,449 - 19,295,913 (-)NCBI
Sequence:
RefSeq Acc Id: XP_850450   ⟸   XM_845357
- UniProtKB: A0A8C0NU16 (UniProtKB/TrEMBL),   A0A8C0JX79 (UniProtKB/TrEMBL),   A0A8I3NQ51 (UniProtKB/TrEMBL),   A0A8C0JXL5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000050657   ⟸   ENSCAFT00000067884
Ensembl Acc Id: ENSCAFP00000038369   ⟸   ENSCAFT00000044474
Ensembl Acc Id: ENSCAFP00000055263   ⟸   ENSCAFT00000072819
RefSeq Acc Id: XP_038353321   ⟸   XM_038497393
RefSeq Acc Id: XP_038479745   ⟸   XM_038623817
RefSeq Acc Id: XP_038545511   ⟸   XM_038689583
- UniProtKB: A0A8C0NU16 (UniProtKB/TrEMBL),   A0A8C0JX79 (UniProtKB/TrEMBL),   A0A8I3NQ51 (UniProtKB/TrEMBL),   A0A8C0JXL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415742   ⟸   XM_038559814
- UniProtKB: A0A8C0JX79 (UniProtKB/TrEMBL),   A0A8C0JXL5 (UniProtKB/TrEMBL),   A0A8C0NU16 (UniProtKB/TrEMBL),   A0A8I3NQ51 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845018508   ⟸   ENSCAFT00845023574
Ensembl Acc Id: ENSCAFP00845018515   ⟸   ENSCAFT00845023589
Protein Domains
Hint


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029968 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018346 UniProtKB/TrEMBL
  ENSCAFG00040011805 UniProtKB/TrEMBL
  ENSCAFG00845013237 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000044474.3 UniProtKB/TrEMBL
  ENSCAFT00000072819.2 UniProtKB/TrEMBL
  ENSCAFT00030033785.1 UniProtKB/TrEMBL
  ENSCAFT00040021768.1 UniProtKB/TrEMBL
  ENSCAFT00845023574 ENTREZGENE
  ENSCAFT00845023574.1 UniProtKB/TrEMBL
  ENSCAFT00845023589.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1380.10 UniProtKB/TrEMBL
  Hedgehog/Intein (Hint) domain UniProtKB/TrEMBL
InterPro Hedgehog UniProtKB/TrEMBL
  Hedgehog_Hint UniProtKB/TrEMBL
  Hedgehog_sig/DD-Pept_Zn-bd_sf UniProtKB/TrEMBL
  Hedgehog_Signaling UniProtKB/TrEMBL
  Hedgehog_signalling_dom UniProtKB/TrEMBL
  Hint_dom_C UniProtKB/TrEMBL
  Hint_dom_N UniProtKB/TrEMBL
  Hint_dom_sf UniProtKB/TrEMBL
  Intein_N UniProtKB/TrEMBL
KEGG Report cfa:608860 UniProtKB/TrEMBL
NCBI Gene SHH ENTREZGENE
PANTHER HEDGEHOG UniProtKB/TrEMBL
  SONIC HEDGEHOG PROTEIN UniProtKB/TrEMBL
Pfam HH_signal UniProtKB/TrEMBL
  Hint UniProtKB/TrEMBL
PIRSF Peptidase_C46 UniProtKB/TrEMBL
PRINTS SONICHHOG UniProtKB/TrEMBL
PROSITE INTEIN_N_TER UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART HintC UniProtKB/TrEMBL
  HintN UniProtKB/TrEMBL
Superfamily-SCOP SSF51294 UniProtKB/TrEMBL
  SSF55166 UniProtKB/TrEMBL
UniProt A0A8C0JX79 ENTREZGENE
  A0A8C0JXL5 ENTREZGENE
  A0A8C0NU16 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQ51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NRD7_CANLF UniProtKB/TrEMBL
  A0A8P0P4N0_CANLF UniProtKB/TrEMBL
  F5ANK3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46147 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-20 SHH  sonic hedgehog signaling molecule    sonic hedgehog  Symbol and/or name change 5135510 APPROVED