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70 records found for search term Pdcd1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1311658Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); PARTI9101866124101879278Rat178symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1323231PDCD1programmed cell death 1Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiatio2241849884241858894Human256symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1323232Pdcd1programmed cell death 1Predicted to enable signaling receptor activity. Involved in negative regulation of immune response. Acts upstream of or within negative regulation of B cell apoptotic process; negative regulation of tolerance induction; and positive regulation of T cell apoptotic process. Located in external side o19396602793980278Mouse270symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8979025Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOCNW_0049555424929057747Chinchilla109symbolgene, protein-coding, MODEL [RefSeq]
12157317PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of T cell activation (ortholog); negative regulation of T cell mediated immune response t255160655951618903Dog112symbolgene, protein-coding, PROVISIONAL [RefSeq]
12508258Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); ANW_004936745152571163712Squirrel114symbolgene, protein-coding, MODEL [RefSeq]
13906369PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); APig113symbolgene, protein-coding, PROVISIONAL [RefSeq]
18493263PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of tolerance induction (ortholog); positive regulation of apoptotic process (ortholog); AGreen Monkey120symbolgene, protein-coding, MODEL [RefSeq]
18932577Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of T cell activation (ortholog); negative regulation of T cell mediated immune response tNaked Mole-Rat112symbolgene, protein-coding, MODEL [RefSeq]
32728868PDCD1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOC12130849353130858776Bonobo109symbolgene, protein-coding, MODEL [RefSeq]
287996291pdcd1Tropical Clawed Frogsymbolgene, null
625834270Pdcd1programmed cell death 1ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); ASSOCBlack Rat109symbolgene, protein-coding, MODEL [RefSeq]
287996237pdcd1.LAfrican Clawed Frogsymbolgene, null
329329968pdcd1.SAfrican Clawed Frogsymbolgene, null
32729585LOC117975274programmed cell death protein 1-like12130940566130951059Bonoboold_gene_symbolgene, protein-coding, MODEL [RefSeq]
1605963VSIRV-set immunoregulatory receptorEnables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of metabolic process; and regulation of T cell activation. Located in plasma membrane. [107174755671773520Human109old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1553554Cd274CD274 antigenThe protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domai192933942829365495Mouse404old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1605684CD274CD274 moleculeThis gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of954505425470554Human325old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1306403Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH Spinal Cord Injuries; a1236572497236637490Rat82symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1314998PDCD1LG2programmed cell death 1 ligand 2Involved in negative regulation of activated T cell proliferation; negative regulation of interleukin-10 production; and negative regulation of type II interferon production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonar955105315571282Human87symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1552436Pdcd1lg2programmed cell death 1 ligand 2Acts upstream of or within negative regulation of T cell proliferation and positive regulation of T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system epithelium; 192938831929450327Mouse110symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1351056PDCD10programmed cell death 10This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, an3167683298167734892Human250symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1359329Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia; negative regulation of inflammatory response; positive regulation of mesenchymal cell apoptotic process; ASSOCIATED WITH Subarachnoid Hemorrhage; varicocele; arteriovenous malformat2162602516162644690Rat169symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1550654Pdcd10programmed cell death 10Predicted to enable protein homodimerization activity and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in Golgi membrane; cell periphery; and cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Is expressed37542379775464159Mouse237symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8990026Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthNW_0049554481686657716887215Chinchilla76symbolgene, protein-coding, MODEL [RefSeq]
11708405PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH ar3164703909164755085Bonobo82symbolgene, protein-coding, MODEL [RefSeq]
12209768PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arteriovenous malformations of the br343251210932553524Dog82symbolgene, protein-coding, MODEL [RefSeq]
12662444Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arNW_00493659346506244693387Squirrel82symbolgene, protein-coding, MODEL [RefSeq]
13955217PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arteriovenous malformations of the brPig82symbolgene, protein-coding, PROVISIONAL [RefSeq]
18751208PDCD10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH arGreen Monkey82symbolgene, protein-coding, MODEL [RefSeq]
18926511Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthNaked Mole-Rat82symbolgene, protein-coding, MODEL [RefSeq]
155257051pdcd10Tropical Clawed Frogsymbolgene, null
625928641Pdcd10programmed cell death 10ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia (ortholog); cellular response to leukemia inhibitory factor (ortholog); establishment of Golgi localization (ortholog); ASSOCIATED WITH arteriovenous malformations of the brain (orthBlack Rat76symbolgene, protein-coding, MODEL [RefSeq]
1304933Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodi1255922198255963336Rat102symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1312660Pdcd11programmed cell death 11Predicted to enable NF-kappaB binding activity and RNA binding activity. Predicted to be involved in rRNA processing. Located in cytosol. Is expressed in several structures, including blastocyst; brain; early embryo; olfactory epithelium; and thymus primordium. Orthologous to human PDCD1194707918347119585Mouse99symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1354347PDCD11programmed cell death 11PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplie10103396626103446294Human100symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
9019729Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog)NW_00495548571107047152301Chinchilla6symbolgene, protein-coding, MODEL [RefSeq]
11885633PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)1099994509100043784Bonobo15symbolgene, protein-coding, MODEL [RefSeq]
12421525PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)281576793615812285Dog15symbolgene, protein-coding, MODEL [RefSeq]
12534979Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)NW_00493660026315202676315Squirrel15symbolgene, protein-coding, MODEL [RefSeq]
14131051PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)Pig15symbolgene, protein-coding, MODEL [RefSeq]
18665441PDCD11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)Green Monkey15symbolgene, protein-coding, MODEL [RefSeq]
18910497Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog)Naked Mole-Rat13symbolgene, protein-coding, MODEL [RefSeq]
155242245pdcd11Tropical Clawed Frogsymbolgene, null
625868617Pdcd11programmed cell death 11ENCODES a protein that exhibits NF-kappaB binding (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog)Black Rat6symbolgene, protein-coding, MODEL [RefSeq]
155253770pdcd10.LAfrican Clawed Frogsymbolgene, null
155243231pdcd10.SAfrican Clawed Frogsymbolgene, null
155233812pdcd11.LAfrican Clawed Frogsymbolgene, null
8805014Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oNW_00495543495400479559335Chinchilla21symbolgene, protein-coding, MODEL [RefSeq]
12012241PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmania953130715391676Bonobo32symbolgene, protein-coding, MODEL [RefSeq]
12115593PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmania19363167693698560Dog33symbolgene, protein-coding, MODEL [RefSeq]
12602259Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaNW_004936539190583229936Squirrel29symbolgene, protein-coding, MODEL [RefSeq]
13859274PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaPig33symbolgene, protein-coding, PROVISIONAL [RefSeq]
18542162PDCD1LG2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN negative regulation of T cell proliferation (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH autoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); cutaneous leishmaniaGreen Monkey32symbolgene, protein-coding, MODEL [RefSeq]
18918713Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oNaked Mole-Rat21symbolgene, protein-coding, MODEL [RefSeq]
285812707pdcd1lg2Tropical Clawed Frogsymbolgene, null
626064547Pdcd1lg2programmed cell death 1 ligand 2ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH autoimmune hepatitis (oBlack Rat21symbolgene, protein-coding, MODEL [RefSeq]
284378902pdcd1lg2.LAfrican Clawed Frogsymbolgene, null
287692237pdcd1lg2.SAfrican Clawed Frogsymbolgene, null
1320536AVENapoptosis and caspase activation inhibitorInvolved in negative regulation of apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]153385178134075325Human94old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1566211Cd274CD274 moleculeENCODES a protein that exhibits receptor ligand activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN positive regulation of cell migration; positive regulation of T cell proliferation; cell surface receptor signaling pathway (ortholog); ASSOCIATED WITH Corneal Graft Reject1236526215236549956Rat314old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1561612Pgcka1PDCD10 and GCKIII kinases associated 1ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); 3-methylcholanthrene (ortholog); 4,4'-sulfonyldiphenol (ortholog)144474096544832180Rat53old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1602474PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle; ASSOCIATED WITH cholestasis; FOUND IN cell periphery; INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; 4,4'-sulfonyldiphenol43745325537593510Human52old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1617462Pgcka1PDCD10 and GCKIII kinases associated 1Is expressed in brain; gut; respiratory system; submandibular gland primordium; and urinary system. Orthologous to human PGCKA1 (PDCD10 and GCKIII kinases associated 1). [provided by Alliance of Genome Resources, Apr 2025]56396983364056968Mouse64old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
8981616Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog)NW_00495544395400479628483Chinchilla7namegene, protein-coding, MODEL [RefSeq]
11704093PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)43178151531922413Bonobo7namegene, protein-coding, MODEL [RefSeq]
12692554Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)NW_00493648255926675614527Squirrel7namegene, protein-coding, MODEL [RefSeq]
18725637PGCKA1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (inferred); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (inferred)Green Monkey7namegene, protein-coding, MODEL [RefSeq]
626163965Pgcka1PDCD10 and GCKIII kinases associated 1INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog)Black Rat7namegene, protein-coding, MODEL [RefSeq]
16559702AC087272.1programmed cell death 10 (PDCD10) pseudogeneHumannamegene, processed_pseudogene