Rsad2 (radical S-adenosyl methionine domain containing 2) - Rat Genome Database

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Gene: Rsad2 (radical S-adenosyl methionine domain containing 2) Rattus norvegicus
Analyze
Symbol: Rsad2
Name: radical S-adenosyl methionine domain containing 2
RGD ID: 620495
Description: Predicted to enable 4 iron, 4 sulfur cluster binding activity. Involved in ossification and regulation of ossification. Predicted to be located in several cellular components, including fibrillar center; lipid droplet; and mitochondrial membrane. Predicted to be active in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in respiratory syncytial virus infectious disease. Orthologous to human RSAD2 (radical S-adenosyl methionine domain containing 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Best5; bone-expressed sequence tag 5 protein; radical S-adenosyl methionine domain-containing protein 2; S-adenosylmethionine-dependent nucleotide dehydratase RSAD2; SAND; Vig1; viperin; virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8648,774,985 - 48,788,245 (-)NCBIGRCr8
mRatBN7.2643,046,514 - 43,059,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl643,047,658 - 43,059,699 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx643,359,103 - 43,372,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0643,673,963 - 43,687,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0643,107,103 - 43,120,223 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0645,655,947 - 45,669,083 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl645,655,954 - 45,669,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0654,375,724 - 54,388,860 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4644,100,775 - 44,113,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1644,103,900 - 44,117,036 (-)NCBI
Celera642,313,474 - 42,326,629 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rsad2RatAnimal Disease Models  ISORSAD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:36071497
Rsad2Ratcongestive heart failure  ISORSAD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:36071497
Rsad2RatHuman Influenza  ISORSAD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23326326
Rsad2RatMyocardial Ischemia  ISORSAD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16214533

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Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Rsad2Rat(-)-alpha-phellandrene increases expressionISORSAD2 (Homo sapiens)6480464alpha phellandrene results in increased expression of RSAD2 mRNACTDPMID:25075043
Rsad2Rat(1->4)-beta-D-glucan multiple interactionsISORsad2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RSAD2 mRNACTDPMID:36331819
Rsad2Rat(S)-nicotine multiple interactionsISORSAD2 (Homo sapiens)6480464[nickel chloride co-treated with Nicotine] results in increased expression of RSAD2 mRNACTDPMID:37951547
Rsad2Rat1,2-dichloroethane decreases expressionISORsad2 (Mus musculus)6480464ethylene dichloride results in decreased expression of RSAD2 mRNACTDPMID:28960355
Rsad2Rat1,2-dimethylhydrazine affects expressionISORsad2 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of RSAD2 mRNACTDPMID:22206623
Rsad2Rat17beta-estradiol increases expressionISORSAD2 (Homo sapiens)6480464Estradiol results in increased expression of RSAD2 mRNACTDPMID:21185374
Rsad2Rat17beta-estradiol decreases expressionISORsad2 (Mus musculus)6480464Estradiol results in decreased expression of RSAD2 mRNACTDPMID:39298647
Rsad2Rat2,2',4,4',5,5'-hexachlorobiphenyl increases expressionISORSAD2 (Homo sapiens)64804642 more ...CTDPMID:23146750
Rsad2Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionISORSAD2 (Homo sapiens)64804642 more ...CTDPMID:23146750
Rsad2Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISORsad2 (Mus musculus)64804642 more ...CTDPMID:30294300
Rsad2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORsad2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of RSAD2 mRNACTDPMID:19770486
Rsad2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RSAD2 mRNACTDPMID:19692669 more ...
Rsad2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of RSAD2 mRNACTDPMID:22298810
Rsad2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464AHR protein alternative form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RSAD2 mRNA]CTDPMID:21215274
Rsad2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORSAD2 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of RSAD2 mRNACTDPMID:22298810
Rsad2Rat2,4,6-trinitrotoluene affects expressionEXP 6480464Trinitrotoluene affects the expression of RSAD2 mRNACTDPMID:21346803
Rsad2Rat2,4-diaminotoluene increases expressionISORsad2 (Mus musculus)64804642 and 4-diaminotoluene results in increased expression of RSAD2 mRNACTDPMID:20713471
Rsad2Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISORsad2 (Mus musculus)64804642 more ...CTDPMID:38648751
Rsad2Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of RSAD2 mRNACTDPMID:21346803
Rsad2Rat2-acetamidofluorene decreases expressionISORsad2 (Mus musculus)64804642-Acetylaminofluorene results in decreased expression of RSAD2 mRNACTDPMID:20713471

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Biological Process
1 to 20 of 41 rows

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rsad2RatCD4-positive, alpha-beta T cell activation involved_inISSUniProtKB:Q8CBB91600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2RatCD4-positive, alpha-beta T cell activation involved_inIEAUniProtKB:Q8CBB9 and ensembl:ENSMUSP000000209701600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2RatCD4-positive, alpha-beta T cell activation involved_inISORsad2 (Mus musculus)1624291 PMID:19047684RGDPMID:19047684
Rsad2RatCD4-positive, alpha-beta T cell differentiation involved_inISORsad2 (Mus musculus)1624291 PMID:19047684RGDPMID:19047684
Rsad2RatCD4-positive, alpha-beta T cell differentiation involved_inISSUniProtKB:Q8CBB91600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2RatCD4-positive, alpha-beta T cell differentiation involved_inIEAUniProtKB:Q8CBB9 and ensembl:ENSMUSP000000209701600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratdefense response to virus involved_inISSUniProtKB:Q8WXG11600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2Ratdefense response to virus involved_inIBAMGI:1929628 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rsad2Ratdefense response to virus involved_inIEAUniProtKB-KW:KW-00511600115GO_REF:0000043UniProtGO_REF:0000043
Rsad2Ratdefense response to virus involved_inIEAInterPro:IPR0263721600115GO_REF:0000002InterProGO_REF:0000002
Rsad2Ratdefense response to virus involved_inISORsad2 (Mus musculus)1624291 PMID:17686841RGDPMID:17686841
Rsad2Ratdefense response to virus involved_inISORSAD2 (Homo sapiens)1624291 PMID:16108059 more ...RGDPMID:16108059 more ...
Rsad2Ratdefense response to virus involved_inIEAUniProtKB:Q8CBB9 and ensembl:ENSMUSP000000209701600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratdefense response to virus involved_inIEAUniProtKB:Q8WXG1 and ensembl:ENSP000003714711600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Rsad2Ratinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
Rsad2Ratnegative regulation of protein secretion involved_inISORSAD2 (Homo sapiens)1624291 PMID:19074433RGDPMID:19074433
Rsad2Ratnegative regulation of protein secretion involved_inIEAUniProtKB:Q8WXG1 and ensembl:ENSP000003714711600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratnegative regulation of protein secretion involved_inISSUniProtKB:Q8WXG11600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2Ratnegative regulation of viral genome replication involved_inIEAUniProtKB:Q8CBB9 and ensembl:ENSMUSP000000209701600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 20 of 37 rows

  
Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Rsad2Ratendoplasmic reticulum located_inISORSAD2 (Homo sapiens)1624291 PMID:11752458 and PMID:21527675RGDGO_REF:0000052 more ...
Rsad2Ratendoplasmic reticulum located_inIEAUniProtKB:Q8WXG1 and ensembl:ENSP000003714711600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Rsad2Ratendoplasmic reticulum part_ofIEAUniProtKB:Q8CBB9 and ensembl:ENSMUSP000000209701600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratendoplasmic reticulum is_active_inIBAMGI:1929628 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rsad2Ratendoplasmic reticulum located_inISORsad2 (Mus musculus)1624291 PMID:23160199RGDPMID:23160199
Rsad2Ratendoplasmic reticulum located_inISSUniProtKB:Q8WXG11600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Rsad2Ratendoplasmic reticulum membrane located_inISSUniProtKB:Q8WXG11600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2Ratendoplasmic reticulum membrane located_inIEAInterPro:IPR0263721600115GO_REF:0000002InterProGO_REF:0000002
Rsad2Ratendoplasmic reticulum membrane located_inIEAUniProtKB:Q8WXG1 and ensembl:ENSP000003714711600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2Ratendoplasmic reticulum membrane located_inISORSAD2 (Homo sapiens)1624291 PMID:19074433RGDPMID:19074433
Rsad2Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Rsad2Ratfibrillar center located_inISORSAD2 (Homo sapiens)1624291 RGDGO_REF:0000052
Rsad2Ratfibrillar center located_inIEAUniProtKB:Q8WXG1 and ensembl:ENSP000003714711600115GO_REF:0000107EnsemblGO_REF:0000107
Rsad2RatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Rsad2RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Rsad2Ratlipid droplet located_inISSUniProtKB:Q8CBB91600115GO_REF:0000024UniProtGO_REF:0000024
Rsad2Ratlipid droplet located_inIEAUniProtKB-SubCell:SL-01541600115GO_REF:0000044UniProtGO_REF:0000044
Rsad2Ratlipid droplet located_inIEAUniProtKB-KW:KW-05511600115GO_REF:0000043UniProtGO_REF:0000043
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Molecular Function
1 to 12 of 12 rows

  
1 to 12 of 12 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rsad2Ratinfluenza A pathway  IEA 6907045 KEGGrno:05164

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Best5: a novel interferon-inducible gene expressed during bone formation. Grewal TS, etal., FASEB J 2000 Mar;14(3):523-31.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9391139   PMID:11752458   PMID:16108059   PMID:16982913   PMID:17686841   PMID:19047684   PMID:19074433   PMID:19920176   PMID:20176015   PMID:21435586   PMID:21527675   PMID:21880757  
PMID:21957124   PMID:23160199  



Rsad2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8648,774,985 - 48,788,245 (-)NCBIGRCr8
mRatBN7.2643,046,514 - 43,059,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl643,047,658 - 43,059,699 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx643,359,103 - 43,372,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0643,673,963 - 43,687,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0643,107,103 - 43,120,223 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0645,655,947 - 45,669,083 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl645,655,954 - 45,669,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0654,375,724 - 54,388,860 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4644,100,775 - 44,113,910 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1644,103,900 - 44,117,036 (-)NCBI
Celera642,313,474 - 42,326,629 (-)NCBICelera
Cytogenetic Map6q16NCBI
RSAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3826,865,885 - 6,898,239 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl26,865,557 - 6,898,239 (+)EnsemblGRCh38hg38GRCh38
GRCh3727,006,016 - 7,038,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3626,935,247 - 6,955,814 (+)NCBINCBI36Build 36hg18NCBI36
Build 3426,968,505 - 6,988,515NCBI
Celera26,930,748 - 6,951,316 (+)NCBICelera
Cytogenetic Map2p25.2NCBI
HuRef26,865,409 - 6,885,974 (+)NCBIHuRef
CHM1_126,947,350 - 6,967,911 (+)NCBICHM1_1
T2T-CHM13v2.026,887,387 - 6,919,736 (+)NCBIT2T-CHM13v2.0
Rsad2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391226,492,742 - 26,506,451 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1226,492,745 - 26,506,451 (-)EnsemblGRCm39 Ensembl
GRCm381226,442,743 - 26,456,452 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1226,442,746 - 26,456,452 (-)EnsemblGRCm38mm10GRCm38
MGSCv371227,127,608 - 27,141,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361227,029,021 - 27,042,699 (-)NCBIMGSCv36mm8
Celera1227,901,184 - 27,914,822 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map129.69NCBI
Rsad2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554871,987,405 - 2,001,731 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554871,988,226 - 2,001,731 (-)NCBIChiLan1.0ChiLan1.0
RSAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212119,613,920 - 119,646,167 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A119,617,895 - 119,650,127 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A6,873,821 - 6,906,087 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A7,010,762 - 7,042,500 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A7,021,937 - 7,042,961 (+)Ensemblpanpan1.1panPan2
RSAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1174,488,202 - 4,508,705 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl174,487,957 - 4,507,181 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha174,413,914 - 4,434,446 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0174,590,443 - 4,611,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl174,590,447 - 4,611,103 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1174,478,041 - 4,498,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0174,486,485 - 4,506,800 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0174,500,286 - 4,520,826 (+)NCBIUU_Cfam_GSD_1.0
Rsad2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629249,163,650 - 49,180,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365323,921,807 - 3,936,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365323,921,824 - 3,936,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RSAD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3128,877,186 - 128,897,815 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13128,880,853 - 128,897,809 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23137,666,404 - 137,683,529 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RSAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114100,778,801 - 100,804,205 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14100,778,302 - 100,798,044 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604511,543,806 - 11,563,560 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rsad2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248463,395,406 - 3,408,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248463,395,536 - 3,408,616 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rsad2
65 total Variants

Predicted Target Of
Summary Value
Count of predictions:540
Count of miRNA genes:245
Interacting mature miRNAs:298
Transcripts:ENSRNOT00000010092
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat

1 to 10 of 25 rows
RH130993  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2643,046,750 - 43,046,969 (+)MAPPERmRatBN7.2
Rnor_6.0645,656,184 - 45,656,402NCBIRnor6.0
Rnor_5.0654,375,961 - 54,376,179UniSTSRnor5.0
RGSC_v3.4644,101,012 - 44,101,230UniSTSRGSC3.4
Celera642,313,711 - 42,313,929UniSTS
RH 3.4 Map6257.8UniSTS
Cytogenetic Map6q16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 47 113 91 90 59 25 59 6 216 95 93 45 59 31



Ensembl Acc Id: ENSRNOT00000010092   ⟹   ENSRNOP00000010092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl643,047,658 - 43,059,699 (-)Ensembl
Rnor_6.0 Ensembl645,655,954 - 45,669,148 (-)Ensembl
RefSeq Acc Id: NM_138881   ⟹   NP_620236
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8648,774,985 - 48,788,120 (-)NCBI
mRatBN7.2643,046,514 - 43,059,651 (-)NCBI
Rnor_6.0645,655,947 - 45,669,083 (-)NCBI
Rnor_5.0654,375,724 - 54,388,860 (-)NCBI
RGSC_v3.4644,100,775 - 44,113,910 (-)RGD
Celera642,313,474 - 42,326,629 (-)RGD
Sequence:
RefSeq Acc Id: XM_039112917   ⟹   XP_038968845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8648,777,688 - 48,788,245 (-)NCBI
mRatBN7.2643,050,064 - 43,059,737 (-)NCBI
Protein RefSeqs NP_620236 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968845 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA68971 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010092
  ENSRNOP00000103974
GenBank Protein O70600 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620236   ⟸   NM_138881
- UniProtKB: O70600 (UniProtKB/Swiss-Prot),   A0A0H2UHF4 (UniProtKB/TrEMBL),   A6HAZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010092   ⟸   ENSRNOT00000010092
RefSeq Acc Id: XP_038968845   ⟸   XM_039112917
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHF4 (UniProtKB/TrEMBL),   A6HAZ9 (UniProtKB/TrEMBL)
Radical SAM core

Name Modeler Protein Id AA Range Protein Structure
AF-O70600-F1-model_v2 AlphaFold O70600 1-360 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694528
Promoter ID:EPDNEW_R5051
Type:single initiation site
Name:Rsad2_1
Description:radical S-adenosyl methionine domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0645,669,096 - 45,669,156EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-37995 BioCyc
Ensembl Genes ENSRNOG00000007539 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010092 ENTREZGENE
  ENSRNOT00000157857 ENTREZGENE
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot
InterPro Aldolase_TIM UniProtKB/Swiss-Prot
  Elp3/MiaB/NifB UniProtKB/Swiss-Prot
  RSAD2 UniProtKB/Swiss-Prot
  RSAD2/Viperin_antiviral UniProtKB/Swiss-Prot
  rSAM UniProtKB/Swiss-Prot
KEGG Report rno:65190 UniProtKB/Swiss-Prot
NCBI Gene 65190 ENTREZGENE
PANTHER RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
  RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
Pfam Fer4_12 UniProtKB/Swiss-Prot
  Radical_SAM UniProtKB/Swiss-Prot
PhenoGen Rsad2 PhenoGen
PROSITE RADICAL_SAM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007539 RatGTEx
SMART Elp3 UniProtKB/Swiss-Prot
Superfamily-SCOP Radical SAM enzymes UniProtKB/Swiss-Prot
UniProt A0A0H2UHF4 ENTREZGENE, UniProtKB/TrEMBL
  A6HAZ9 ENTREZGENE, UniProtKB/TrEMBL
  O70600 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-22 Rsad2  radical S-adenosyl methionine domain containing 2  Best5  Best5 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-08-07 Best5  Best5 protein      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_regulation mRNA expression is induced by interferon-alpha (IFN-alpha) or IFN-gamma in osteoblast cultures 631877