Symbol:
Trpc3
Name:
transient receptor potential cation channel, subfamily C, member 3
RGD ID:
61973
Description:
Enables calcium-activated cation channel activity. Predicted to be involved in several processes, including positive regulation of calcium ion transport into cytosol; positive regulation of cardiac muscle hypertrophy in response to stress; and response to ATP. Predicted to be located in membrane. Predicted to be part of cation channel complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
ion channel protein; short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor protein 3; trp-related protein 3; TrpC3c; Trrp3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TRPC3 (transient receptor potential cation channel subfamily C member 3) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Trpc3 (transient receptor potential cation channel, subfamily C, member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Trpc3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TRPC3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TRPC3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Trpc3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TRPC3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TRPC3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Trpc3 (transient receptor potential cation channel subfamily C member 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Trpc3 (transient receptor potential cation channel, subfamily C, member 3)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
TRPC3 (transient receptor potential cation channel subfamily C member 3)
Alliance
DIOPT (HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
trpc3 (transient receptor potential cation channel, subfamily C, member 3)
Alliance
DIOPT (Hieranoid|OMA|OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
spe-41
Alliance
DIOPT (Ensembl Compara|PANTHER)
Caenorhabditis elegans (roundworm):
trp-1
Alliance
DIOPT (OMA|PANTHER)
Xenopus tropicalis (tropical clawed frog):
trpc3
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER)
Allele / Splice:
Trpc3em2Mcwi
Trpc3em1Mcwi
Genetic Models:
SS-Trpc3em1Mcwi
SS-Trpc3em2Mcwi
Candidate Gene For:
Cm49
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 121,409,436 - 121,487,095 (-) NCBI GRCr8 mRatBN7.2 2 119,481,313 - 119,619,333 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 119,481,400 - 119,558,855 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 126,036,120 - 126,102,387 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 124,148,616 - 124,214,886 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 118,777,565 - 118,843,835 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 123,329,954 - 123,467,574 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 123,329,875 - 123,407,496 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 142,945,309 - 143,022,844 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 123,117,180 - 123,184,016 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 123,062,239 - 123,110,364 (-) NCBI Celera 2 114,439,430 - 114,505,661 (-) NCBI Celera Cytogenetic Map 2 q25 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Trpc3 Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of TRPC3 mRNA CTD PMID:30723492 Trpc3 Rat 1-Oleoyl-2-acetyl-sn-glycerol increases activity ISO Trpc3 (Mus musculus) 6480464 1-oleoyl-2-acetylglycerol results in increased activity of TRPC3 protein CTD PMID:18316702 and PMID:19289841 Trpc3 Rat 1-Oleoyl-2-acetyl-sn-glycerol multiple interactions ISO Trpc3 (Mus musculus) 6480464 ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC3 protein] CTD PMID:19289841 Trpc3 Rat 1-Oleoyl-2-acetyl-sn-glycerol multiple interactions ISO TRPC3 (Homo sapiens) 6480464 1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium] more ... CTD PMID:11042129 more ... Trpc3 Rat 1-Oleoyl-2-acetyl-sn-glycerol increases activity ISO TRPC3 (Homo sapiens) 6480464 1-oleoyl-2-acetylglycerol results in increased activity of TRPC3 protein CTD PMID:16522635 Trpc3 Rat 17beta-estradiol increases expression ISO Trpc3 (Mus musculus) 6480464 Estradiol results in increased expression of TRPC3 mRNA CTD PMID:19484750 Trpc3 Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TRPC3 mRNA and [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TRPC3 mRNA CTD PMID:26496021 and PMID:32741896 Trpc3 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TRPC3 mRNA CTD PMID:32741896 Trpc3 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:27291303 Trpc3 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TRPC3 mRNA CTD PMID:33387578 Trpc3 Rat 2,4,6-trinitrobenzenesulfonic acid decreases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA CTD PMID:23537331 Trpc3 Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Trpc3 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TRPC3 mRNA CTD PMID:26251327 Trpc3 Rat 4,4'-diaminodiphenylmethane increases expression ISO Trpc3 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of TRPC3 mRNA CTD PMID:18648102 Trpc3 Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of TRPC3 mRNA CTD PMID:28959563 Trpc3 Rat aflatoxin B1 decreases expression ISO TRPC3 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of TRPC3 mRNA CTD PMID:22100608 Trpc3 Rat aflatoxin B1 increases expression ISO TRPC3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of TRPC3 protein CTD PMID:27818125 Trpc3 Rat all-trans-retinoic acid increases expression ISO TRPC3 (Homo sapiens) 6480464 Tretinoin results in increased expression of TRPC3 mRNA CTD PMID:21934132 Trpc3 Rat allethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRPC3 protein CTD PMID:34896426 Trpc3 Rat alpha-Zearalanol increases expression ISO TRPC3 (Homo sapiens) 6480464 Zeranol results in increased expression of TRPC3 protein CTD PMID:27224899 Trpc3 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of TRPC3 mRNA CTD PMID:38685447 Trpc3 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TRPC3 mRNA CTD PMID:16483693 Trpc3 Rat aristolochic acid A decreases expression ISO TRPC3 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of TRPC3 mRNA CTD PMID:33212167 Trpc3 Rat arsenite(3-) decreases expression ISO Trpc3 (Mus musculus) 6480464 arsenite results in decreased expression of TRPC3 mRNA CTD PMID:33053406 Trpc3 Rat asbestos affects methylation ISO TRPC3 (Homo sapiens) 6480464 Asbestos affects the methylation of TRPC3 gene CTD PMID:28722770 Trpc3 Rat ATP increases activity ISO Trpc3 (Mus musculus) 6480464 Adenosine Triphosphate results in increased activity of TRPC3 protein CTD PMID:19289841 Trpc3 Rat ATP multiple interactions ISO Trpc3 (Mus musculus) 6480464 ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Adenosine Triphosphate results in increased activity of TRPC3 protein] CTD PMID:19289841 Trpc3 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of TRPC3 gene CTD PMID:35440735 Trpc3 Rat Azoxymethane multiple interactions ISO Trpc3 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPC3 mRNA CTD PMID:29950665 Trpc3 Rat barium(0) multiple interactions ISO Trpc3 (Mus musculus) 6480464 1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC3 protein results in increased transport of Barium] CTD PMID:16055711 Trpc3 Rat barium(0) increases transport ISO Trpc3 (Mus musculus) 6480464 TRPC3 protein results in increased transport of Barium CTD PMID:16055711 Trpc3 Rat barium(0) increases transport ISO TRPC3 (Homo sapiens) 6480464 TRPC3 protein results in increased transport of Barium CTD PMID:11042129 Trpc3 Rat barium(0) multiple interactions ISO TRPC3 (Homo sapiens) 6480464 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium] CTD PMID:11042129 Trpc3 Rat benzene decreases expression ISO Trpc3 (Mus musculus) 6480464 Benzene results in decreased expression of TRPC3 mRNA CTD PMID:37084897 Trpc3 Rat benzo[a]pyrene decreases expression ISO Trpc3 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of TRPC3 mRNA CTD PMID:22228805 Trpc3 Rat benzo[a]pyrene decreases expression ISO TRPC3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of TRPC3 mRNA CTD PMID:32234424 Trpc3 Rat benzo[a]pyrene affects methylation ISO TRPC3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TRPC3 promoter CTD PMID:27901495 Trpc3 Rat benzo[a]pyrene increases methylation ISO TRPC3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of TRPC3 exon CTD PMID:27901495 Trpc3 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of TRPC3 mRNA CTD PMID:26496021 Trpc3 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of TRPC3 gene CTD PMID:28505145 Trpc3 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TRPC3 mRNA CTD PMID:25181051 more ... Trpc3 Rat caffeine multiple interactions ISO Trpc3 (Mus musculus) 6480464 TRPC3 protein affects the reaction [Caffeine results in increased activity of RYR1 protein] CTD PMID:16484216 Trpc3 Rat calcium atom multiple interactions ISO TRPC3 (Homo sapiens) 6480464 1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium] more ... CTD PMID:12700192 and PMID:17351372 Trpc3 Rat calcium atom increases transport EXP 6480464 TRPC3 protein results in increased transport of Calcium CTD PMID:18822394 Trpc3 Rat calcium atom affects transport EXP 6480464 TRPC3 protein affects the transport of Calcium CTD PMID:15672411 Trpc3 Rat calcium atom affects secretion ISO Trpc3 (Mus musculus) 6480464 TRPC3 protein affects the secretion of Calcium CTD PMID:16484216 Trpc3 Rat calcium atom multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium] more ... CTD PMID:15672411 and PMID:19244478 Trpc3 Rat calcium atom increases transport ISO TRPC3 (Homo sapiens) 6480464 TRPC3 protein results in increased transport of Calcium CTD PMID:12700192 and PMID:12736256 Trpc3 Rat calcium atom affects transport ISO TRPC3 (Homo sapiens) 6480464 TRPC3 protein affects the transport of Calcium CTD PMID:17351372 Trpc3 Rat calcium(0) multiple interactions ISO TRPC3 (Homo sapiens) 6480464 1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium] more ... CTD PMID:12700192 and PMID:17351372 Trpc3 Rat calcium(0) increases transport EXP 6480464 TRPC3 protein results in increased transport of Calcium CTD PMID:18822394 Trpc3 Rat calcium(0) affects transport EXP 6480464 TRPC3 protein affects the transport of Calcium CTD PMID:15672411 Trpc3 Rat calcium(0) affects secretion ISO Trpc3 (Mus musculus) 6480464 TRPC3 protein affects the secretion of Calcium CTD PMID:16484216 Trpc3 Rat calcium(0) multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium] more ... CTD PMID:15672411 and PMID:19244478 Trpc3 Rat calcium(0) increases transport ISO TRPC3 (Homo sapiens) 6480464 TRPC3 protein results in increased transport of Calcium CTD PMID:12700192 and PMID:12736256 Trpc3 Rat calcium(0) affects transport ISO TRPC3 (Homo sapiens) 6480464 TRPC3 protein affects the transport of Calcium CTD PMID:17351372 Trpc3 Rat carbachol multiple interactions ISO Trpc3 (Mus musculus) 6480464 ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Carbachol results in increased activity of TRPC3 protein] CTD PMID:19289841 Trpc3 Rat carbachol increases activity ISO Trpc3 (Mus musculus) 6480464 Carbachol results in increased activity of TRPC3 protein CTD PMID:19289841 Trpc3 Rat carbon nanotube decreases expression ISO Trpc3 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Trpc3 Rat CGP 52608 multiple interactions ISO TRPC3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TRPC3 gene] CTD PMID:28238834 Trpc3 Rat CHIR 99021 multiple interactions EXP 6480464 Chir 99021 promotes the reaction [Ketamine results in decreased expression of TRPC3 protein] CTD PMID:36334642 Trpc3 Rat chlorpyrifos increases expression ISO Trpc3 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of TRPC3 mRNA CTD PMID:37019170 Trpc3 Rat cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Thapsigargin results in increased expression of TRPC3 mRNA] CTD PMID:19244478 Trpc3 Rat cyhalothrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRPC3 protein CTD PMID:34896426 Trpc3 Rat cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRPC3 protein CTD PMID:34896426 Trpc3 Rat DDE increases expression ISO TRPC3 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of TRPC3 mRNA CTD PMID:38568856 Trpc3 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of TRPC3 mRNA CTD PMID:23640034 Trpc3 Rat dextran sulfate multiple interactions ISO Trpc3 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPC3 mRNA CTD PMID:29950665 Trpc3 Rat dimethylarsinic acid multiple interactions ISO Trpc3 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPC3 mRNA CTD PMID:34876320 Trpc3 Rat doxorubicin multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Doxorubicin results in increased expression of TRPC3 protein] CTD PMID:28495616 Trpc3 Rat doxorubicin decreases expression ISO TRPC3 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of TRPC3 mRNA CTD PMID:29803840 Trpc3 Rat doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of TRPC3 protein CTD PMID:28495616 Trpc3 Rat fenvalerate multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRPC3 protein CTD PMID:34896426 Trpc3 Rat gadolinium atom multiple interactions ISO TRPC3 (Homo sapiens) 6480464 Gadolinium affects the localization of and results in decreased activity of TRPC3 protein CTD PMID:16522635 Trpc3 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TRPC3 mRNA CTD PMID:33387578 Trpc3 Rat GW 4064 decreases expression ISO Trpc3 (Mus musculus) 6480464 GW 4064 results in decreased expression of TRPC3 mRNA CTD PMID:26655953 Trpc3 Rat ketamine multiple interactions EXP 6480464 Chir 99021 promotes the reaction [Ketamine results in decreased expression of TRPC3 protein] CTD PMID:36334642 Trpc3 Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of TRPC3 mRNA and Ketamine results in decreased expression of TRPC3 protein CTD PMID:36334642 Trpc3 Rat maneb multiple interactions ISO Trpc3 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of TRPC3 mRNA CTD PMID:36117858 Trpc3 Rat methacholine chloride increases activity ISO TRPC3 (Homo sapiens) 6480464 Methacholine Chloride results in increased activity of TRPC3 protein CTD PMID:16522635 Trpc3 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of TRPC3 gene CTD PMID:35440735 Trpc3 Rat methylarsonic acid multiple interactions ISO Trpc3 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPC3 mRNA CTD PMID:34876320 Trpc3 Rat ozone multiple interactions ISO Trpc3 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TRPC3 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of TRPC3 mRNA CTD PMID:27106289 and PMID:34911549 Trpc3 Rat paclitaxel increases expression ISO TRPC3 (Homo sapiens) 6480464 Paclitaxel results in increased expression of TRPC3 protein CTD PMID:15907983 Trpc3 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TRPC3 mRNA and Paraquat results in decreased expression of TRPC3 protein CTD PMID:23602965 Trpc3 Rat paraquat multiple interactions ISO Trpc3 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of TRPC3 mRNA CTD PMID:36117858 Trpc3 Rat phenylephrine multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium] more ... CTD PMID:15672411 and PMID:19244478 Trpc3 Rat phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of TRPC3 mRNA and Phenylephrine results in increased expression of TRPC3 protein CTD PMID:19244478 Trpc3 Rat phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of TRPC3 mRNA CTD PMID:19244478 Trpc3 Rat pioglitazone multiple interactions ISO Trpc3 (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRPC3 mRNA CTD PMID:27935865 Trpc3 Rat pyrethrins decreases expression EXP 6480464 Pyrethrins results in decreased expression of TRPC3 protein CTD PMID:34896426 Trpc3 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of TRPC3 mRNA and Rotenone results in decreased expression of TRPC3 protein CTD PMID:23602965 Trpc3 Rat salvianolic acid B multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Doxorubicin results in increased expression of TRPC3 protein] CTD PMID:28495616 Trpc3 Rat SKF-96365 hydrochloride multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium] CTD PMID:19244478 Trpc3 Rat sodium arsenate multiple interactions ISO Trpc3 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPC3 mRNA CTD PMID:34876320 Trpc3 Rat sodium arsenite multiple interactions ISO Trpc3 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPC3 mRNA CTD PMID:34876320 Trpc3 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TRPC3 mRNA CTD PMID:32741896 Trpc3 Rat tetraphene increases expression ISO Trpc3 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of TRPC3 mRNA CTD PMID:26377693 Trpc3 Rat thapsigargin multiple interactions ISO TRPC3 (Homo sapiens) 6480464 Thapsigargin promotes the reaction [TRPC3 protein results in increased transport of Calcium] CTD PMID:12700192 Trpc3 Rat thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of TRPC3 mRNA CTD PMID:19244478 Trpc3 Rat thapsigargin multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Thapsigargin results in increased expression of TRPC3 mRNA] and TRPC3 protein promotes the reaction [Thapsigargin results in increased transport of Calcium] CTD PMID:15672411 and PMID:19244478 Trpc3 Rat titanium dioxide multiple interactions ISO Trpc3 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPC3 mRNA CTD PMID:29950665 Trpc3 Rat titanium dioxide increases methylation ISO Trpc3 (Mus musculus) 6480464 titanium dioxide results in increased methylation of TRPC3 gene CTD PMID:35295148 Trpc3 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of TRPC3 mRNA CTD PMID:33387578 Trpc3 Rat triclosan decreases expression ISO TRPC3 (Homo sapiens) 6480464 Triclosan results in decreased expression of TRPC3 mRNA CTD PMID:30510588 Trpc3 Rat trimellitic anhydride decreases expression ISO Trpc3 (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of TRPC3 mRNA CTD PMID:19042947 Trpc3 Rat triptonide increases expression ISO Trpc3 (Mus musculus) 6480464 triptonide results in increased expression of TRPC3 mRNA CTD PMID:33045310 Trpc3 Rat troglitazone decreases expression ISO Trpc3 (Mus musculus) 6480464 troglitazone results in decreased expression of TRPC3 mRNA CTD PMID:28973697 Trpc3 Rat UTP increases activity ISO Trpc3 (Mus musculus) 6480464 Uridine Triphosphate results in increased activity of TRPC3 protein CTD PMID:19289841 Trpc3 Rat UTP multiple interactions ISO Trpc3 (Mus musculus) 6480464 ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Uridine Triphosphate results in increased activity of TRPC3 protein] CTD PMID:19289841 Trpc3 Rat valproic acid decreases methylation ISO TRPC3 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of TRPC3 gene CTD PMID:29154799 Trpc3 Rat valproic acid affects expression ISO TRPC3 (Homo sapiens) 6480464 Valproic Acid affects the expression of TRPC3 mRNA CTD PMID:25979313 Trpc3 Rat vinclozolin decreases methylation EXP 6480464 vinclozolin results in decreased methylation of TRPC3 gene CTD PMID:31682807 Trpc3 Rat vorinostat increases expression ISO TRPC3 (Homo sapiens) 6480464 vorinostat results in increased expression of TRPC3 mRNA CTD PMID:27188386
1-naphthyl isothiocyanate (EXP) 1-Oleoyl-2-acetyl-sn-glycerol (ISO) 17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,2',4,4'-Tetrabromodiphenyl ether (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP) 2,4,6-trinitrobenzenesulfonic acid (EXP) 3,4-methylenedioxymethamphetamine (ISO) 4,4'-diaminodiphenylmethane (ISO) acrylamide (EXP) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) allethrin (EXP) alpha-Zearalanol (ISO) amitrole (EXP) ammonium chloride (EXP) aristolochic acid A (ISO) arsenite(3-) (ISO) asbestos (ISO) ATP (ISO) atrazine (EXP) Azoxymethane (ISO) barium(0) (ISO) benzene (ISO) benzo[a]pyrene (ISO) bisphenol A (EXP) caffeine (ISO) calcium atom (EXP,ISO) calcium(0) (EXP,ISO) carbachol (ISO) carbon nanotube (ISO) CGP 52608 (ISO) CHIR 99021 (EXP) chlorpyrifos (ISO) cyclosporin A (EXP) cyhalothrin (EXP) cypermethrin (EXP) DDE (ISO) decabromodiphenyl ether (EXP) dextran sulfate (ISO) dimethylarsinic acid (ISO) doxorubicin (EXP,ISO) fenvalerate (EXP) gadolinium atom (ISO) gentamycin (EXP) GW 4064 (ISO) ketamine (EXP) maneb (ISO) methacholine chloride (ISO) methoxychlor (EXP) methylarsonic acid (ISO) ozone (ISO) paclitaxel (ISO) paraquat (EXP,ISO) phenylephrine (EXP) phorbol 13-acetate 12-myristate (EXP) pioglitazone (ISO) pyrethrins (EXP) rotenone (EXP) salvianolic acid B (EXP) SKF-96365 hydrochloride (EXP) sodium arsenate (ISO) sodium arsenite (ISO) testosterone (EXP) tetraphene (ISO) thapsigargin (EXP,ISO) titanium dioxide (ISO) trichloroethene (EXP) triclosan (ISO) trimellitic anhydride (ISO) triptonide (ISO) troglitazone (ISO) UTP (ISO) valproic acid (ISO) vinclozolin (EXP) vorinostat (ISO)
1.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
3.
Tissue expression of TRPC3 and TRPC6 in hypertensive Munich Wistar Fromter rats showing proteinuria.
Liu Y, etal., Am J Nephrol. 2010;31(1):36-44. doi: 10.1159/000254060. Epub 2009 Oct 30.
4.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
5.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.
A calcium-activated cation current by an alternatively spliced form of Trp3 in the heart.
Ohki G, etal., J Biol Chem 2000 Dec 15;275(50):39055-60.
7.
GOA pipeline
RGD automated data pipeline
8.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
9.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10.
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.
Yu Y, etal., Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13861-6. Epub 2004 Sep 9.
Trpc3 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 121,409,436 - 121,487,095 (-) NCBI GRCr8 mRatBN7.2 2 119,481,313 - 119,619,333 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 119,481,400 - 119,558,855 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 2 126,036,120 - 126,102,387 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 124,148,616 - 124,214,886 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 118,777,565 - 118,843,835 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 123,329,954 - 123,467,574 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 123,329,875 - 123,407,496 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 2 142,945,309 - 143,022,844 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 2 123,117,180 - 123,184,016 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 2 123,062,239 - 123,110,364 (-) NCBI Celera 2 114,439,430 - 114,505,661 (-) NCBI Celera Cytogenetic Map 2 q25 NCBI
TRPC3 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 4 121,874,481 - 121,952,060 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 4 121,874,481 - 121,952,060 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 4 122,795,636 - 122,873,215 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 4 123,019,882 - 123,074,061 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 4 123,158,037 - 123,212,216 NCBI Celera 4 120,186,020 - 120,258,701 (-) NCBI Celera Cytogenetic Map 4 q27 NCBI HuRef 4 118,526,892 - 118,599,598 (-) NCBI HuRef CHM1_1 4 122,776,636 - 122,849,349 (-) NCBI CHM1_1 T2T-CHM13v2.0 4 125,178,529 - 125,256,098 (-) NCBI T2T-CHM13v2.0
Trpc3 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 3 36,674,626 - 36,744,276 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 3 36,674,631 - 36,744,316 (-) Ensembl GRCm39 Ensembl GRCm38 3 36,620,482 - 36,690,429 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 3 36,620,482 - 36,690,167 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 3 36,519,404 - 36,589,089 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 3 36,812,122 - 36,863,152 (-) NCBI MGSCv36 mm8 Celera 3 36,505,427 - 36,575,273 (-) NCBI Celera Cytogenetic Map 3 B NCBI cM Map 3 17.93 NCBI
Trpc3 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955428 18,628,890 - 18,678,906 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955428 18,628,951 - 18,678,525 (+) NCBI ChiLan1.0 ChiLan1.0
TRPC3 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 3 119,675,137 - 119,748,732 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 4 119,944,205 - 120,017,773 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 4 114,079,395 - 114,153,014 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 4 125,217,086 - 125,288,918 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 4 125,217,086 - 125,289,014 (-) Ensembl panpan1.1 panPan2
TRPC3 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 19 18,207,565 - 18,272,551 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 19 18,207,417 - 18,271,828 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 19 18,424,474 - 18,489,427 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 19 18,325,131 - 18,390,132 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 19 18,257,209 - 18,389,851 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 19 18,276,335 - 18,341,249 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 19 18,557,985 - 18,622,931 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 19 19,033,797 - 19,098,726 (+) NCBI UU_Cfam_GSD_1.0
Trpc3 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405301 65,875,569 - 65,989,487 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936662 1,129,278 - 1,171,378 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936662 1,130,555 - 1,171,352 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TRPC3 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 8 102,129,611 - 102,206,946 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 8 102,129,539 - 102,206,512 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 8 109,324,967 - 109,402,046 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TRPC3 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 7 69,160,569 - 69,233,322 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 7 69,158,867 - 69,231,858 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666037 48,122,249 - 48,196,700 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Trpc3
.
Predicted Target Of
Count of predictions: 69 Count of miRNA genes: 60 Interacting mature miRNAs: 68 Transcripts: ENSRNOT00000046700 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1578648 Bss11 Bone structure and strength QTL 11 4.7 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 2 114837527 211674221 Rat 2293671 Bss44 Bone structure and strength QTL 44 10.97 0.0001 lumbar vertebra morphology trait (VT:0010494) lumbar vertebra cortical cross-sectional area (CMO:0001690) 2 43162366 148478373 Rat 631566 Bp90 Blood pressure QTL 90 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 102803808 147803808 Rat 1298074 Bp164 Blood pressure QTL 164 0.003 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 42804607 202447032 Rat 1598865 Bp296 Blood pressure QTL 296 2.1 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 81018907 126018907 Rat 1354648 Bp239 Blood pressure QTL 239 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 66118463 226797303 Rat 1578772 Stresp14 Stress response QTL 14 5 0.001 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 2 82345893 130923501 Rat 1354649 Kidm17 Kidney mass QTL 17 2.9 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 2 81754530 227146641 Rat 10755499 Bp389 Blood pressure QTL 389 2.61 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 18960362 228801039 Rat 152025242 Bw191 Body weight QTL 191 3.62 body mass (VT:0001259) 2 38573329 122609194 Rat 1598862 Glom9 Glomerulus QTL 9 3.5 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 2 92337601 137337601 Rat 631198 Cm22 Cardiac mass QTL 22 4.3 0.0008 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 2 76539322 150540526 Rat 1598863 Cm65 Cardiac mass QTL 65 2.3 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 92337601 137337601 Rat 1554319 Bmd2 Bone mineral density QTL 2 13.4 0.0001 lumbar vertebra area (VT:0010570) lumbar vertebra cross-sectional area (CMO:0001689) 2 114837675 212549332 Rat 1302794 Stl27 Serum triglyceride level QTL 27 4.4 0.0001 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 2 25413423 143657569 Rat 1581569 Uae32 Urinary albumin excretion QTL 32 0.0001 urine protein amount (VT:0005160) urine albumin excretion rate (CMO:0000757) 2 78665619 219826953 Rat 61467 Bp14 Blood pressure QTL 14 2.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 43154682 202446871 Rat 1358901 Cm38 Cardiac mass QTL 38 2 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 157142209 Rat 1359030 Bp277 Blood pressure QTL 277 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 114837527 185876470 Rat 1331760 Bp206 Blood pressure QTL 206 3.62454 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 56043031 202447032 Rat 2300165 Bmd49 Bone mineral density QTL 49 4.8 0.0001 lumbar vertebra mineral mass (VT:0010511) bone mineral density (CMO:0001226) 2 88862519 133862519 Rat 1358899 Kidm23 Kidney mass QTL 23 3.88 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 25413423 157142209 Rat 1358908 Bw49 Body weight QTL 49 3.36 body mass (VT:0001259) body weight (CMO:0000012) 2 25413652 157142078 Rat 2300170 Bmd45 Bone mineral density QTL 45 12.1 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 2 88862519 133862519 Rat 1582257 Gluco21 Glucose level QTL 21 3.1 0.0035 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 2 118111229 157142209 Rat 1358910 Kidm27 Kidney mass QTL 27 5.77 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 25413423 157142209 Rat 1358911 Kidm28 Kidney mass QTL 28 5.42 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 25413423 157142209 Rat 1358904 Cm39 Cardiac mass QTL 39 2.26 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 157142209 Rat 1359035 Bp276 Blood pressure QTL 276 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 114837527 143657569 Rat 8662836 Vetf8 Vascular elastic tissue fragility QTL 8 0.66 thoracic aorta molecular composition trait (VT:0010568) aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003) 2 104559726 149559726 Rat 1358887 Bw50 Body weight QTL 50 2.39 body mass (VT:0001259) body weight (CMO:0000012) 2 25413652 157142078 Rat 1298080 Bp163 Blood pressure QTL 163 0.02 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 66118275 202447032 Rat 8662832 Vetf7 Vascular elastic tissue fragility QTL 7 3.5 aorta elastin amount (VT:0003905) aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002) 2 81689826 221035911 Rat 5135226 Leukc2 Leukocyte quantity QTL 2 eosinophil quantity (VT:0002602) blood eosinophil count (CMO:0000033) 2 118111229 149559726 Rat 1298085 Bp165 Blood pressure QTL 165 0.0006 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 42804607 202447032 Rat 2290453 Scl55 Serum cholesterol level QTL 55 2.83 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 2 26917817 136917119 Rat 2299162 Iddm32 Insulin dependent diabetes mellitus QTL 32 2.36 blood glucose amount (VT:0000188) age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140) 2 78665616 143657569 Rat 1358894 Kidm24 Kidney mass QTL 24 4.03 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 2 25413423 157142209 Rat 2300185 Bmd46 Bone mineral density QTL 46 8.4 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 2 88862519 133862519 Rat 724534 Uae6 Urinary albumin excretion QTL 6 10 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 2 78665619 249053267 Rat 61374 Edpm2 Estrogen-dependent pituitary mass QTL 2 4.42 0.86 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 2 76539322 202447032 Rat 634308 Sach6 Saccharin preference QTL 6 4.9 taste sensitivity trait (VT:0001986) saccharin intake volume to total fluid intake volume ratio (CMO:0001601) 2 112456140 212696837 Rat 61392 Bp6 Blood pressure QTL 6 7 arterial blood pressure trait (VT:2000000) pulse pressure (CMO:0000292) 2 80270434 125270434 Rat 1358917 Cm42 Cardiac mass QTL 42 2.82 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 203928301 Rat 1358913 Cm41 Cardiac mass QTL 41 2.73 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 2 25413423 203928301 Rat 631507 Bp105 Blood pressure QTL 105 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 2 112456140 212696837 Rat 738007 Anxrr7 Anxiety related response QTL 7 4.4 exploratory behavior trait (VT:0010471) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 2 118189491 163189491 Rat 2293835 Kiddil5 Kidney dilation QTL 5 3.8 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 42804607 157142209 Rat 1581552 Pur12 Proteinuria QTL 12 5.19 0.0009 urine total protein amount (VT:0000032) urine protein excretion rate (CMO:0000759) 2 112103657 148076632 Rat 1558653 Prcr1 Prostate cancer resistance QTL 1 5 prostate integrity trait (VT:0010571) area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899) 2 72532993 157142209 Rat 1354622 Kidm16 Kidney mass QTL 16 3 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 2 81754530 222436696 Rat 631266 Bp132 Blood pressure QTL 132 0.0005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 2 46123260 202447032 Rat 7207808 Bmd89 Bone mineral density QTL 89 4.1 femur strength trait (VT:0010010) femoral neck ultimate force (CMO:0001703) 2 88862519 133862519 Rat 1558648 Smcn1 Smooth muscle cell number QTL 1 0.039 blood vessel smooth muscle cell quantity (VT:0010525) aorta smooth muscle cell count per unit vessel length (CMO:0001646) 2 59134147 127460910 Rat 2293843 Kiddil6 Kidney dilation QTL 6 3.1 kidney pelvis morphology trait (VT:0004194) hydronephrosis severity score (CMO:0001208) 2 42804607 182042367 Rat 1354594 Despr10 Despair related QTL 10 2e-06 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 2 114654253 159654253 Rat 152025206 Hrtrt23 Heart rate QTL 23 5.98 heart pumping trait (VT:2000009) 2 28484589 169504100 Rat 1354605 Rf48 Renal function QTL 48 2.9 blood creatinine amount (VT:0005328) plasma creatinine level (CMO:0000537) 2 74786664 206665859 Rat 152025204 Hrtrt22 Heart rate QTL 22 5.6 heart pumping trait (VT:2000009) 2 28484589 169504100 Rat 1354601 Slep1 Serum leptin concentration QTL 1 5.39 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 2 43171017 184114403 Rat 61438 Cia7 Collagen induced arthritis QTL 7 4.6 0.0001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 2 59324377 141596857 Rat 1354603 Bp243 Blood pressure QTL 243 3.9 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 2 26917817 127469484 Rat
D2Rat340
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 2 121,439,886 - 121,440,099 (+) Marker Load Pipeline Rnor_6.0 2 123,360,405 - 123,360,640 NCBI Rnor6.0 Rnor_5.0 2 142,975,758 - 142,975,970 UniSTS Rnor5.0 RGSC_v3.4 2 123,147,918 - 123,148,131 RGD RGSC3.4 RGSC_v3.4 2 123,147,919 - 123,148,131 UniSTS RGSC3.4 RGSC_v3.1 2 123,092,880 - 123,093,093 RGD Celera 2 114,469,851 - 114,470,051 UniSTS SHRSP x BN Map 2 44.4298 RGD SHRSP x BN Map 2 44.4298 UniSTS Cytogenetic Map 2 q25 UniSTS
D2Got77
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 119,519,366 - 119,519,543 (+) MAPPER mRatBN7.2 Rnor_6.0 2 123,368,030 - 123,368,208 NCBI Rnor6.0 Rnor_5.0 2 142,983,360 - 142,983,536 UniSTS Rnor5.0 RGSC_v3.4 2 123,155,520 - 123,155,699 RGD RGSC3.4 RGSC_v3.4 2 123,155,521 - 123,155,699 UniSTS RGSC3.4 RGSC_v3.1 2 123,100,483 - 123,100,661 RGD Celera 2 114,477,427 - 114,477,605 UniSTS RH 3.4 Map 2 675.0 RGD RH 3.4 Map 2 675.0 UniSTS Cytogenetic Map 2 q25 UniSTS
RH129709
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 119,549,285 - 119,549,473 (+) MAPPER mRatBN7.2 Rnor_6.0 2 123,397,941 - 123,398,128 NCBI Rnor6.0 Rnor_5.0 2 143,013,259 - 143,013,446 UniSTS Rnor5.0 RGSC_v3.4 2 123,186,812 - 123,186,999 UniSTS RGSC3.4 Celera 2 114,507,201 - 114,507,388 UniSTS RH 3.4 Map 2 673.4 UniSTS Cytogenetic Map 2 q25 UniSTS
RH144026
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 119,481,538 - 119,481,642 (+) MAPPER mRatBN7.2 Rnor_6.0 2 123,330,180 - 123,330,283 NCBI Rnor6.0 Rnor_5.0 2 142,945,535 - 142,945,638 UniSTS Rnor5.0 RGSC_v3.4 2 123,117,319 - 123,117,422 UniSTS RGSC3.4 Celera 2 114,439,569 - 114,439,672 UniSTS RH 3.4 Map 2 675.3 UniSTS Cytogenetic Map 2 q25 UniSTS
BE116826
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 119,496,187 - 119,496,392 (+) MAPPER mRatBN7.2 Rnor_6.0 2 123,344,829 - 123,345,033 NCBI Rnor6.0 Rnor_5.0 2 142,960,184 - 142,960,388 UniSTS Rnor5.0 RGSC_v3.4 2 123,132,341 - 123,132,545 UniSTS RGSC3.4 Celera 2 114,454,216 - 114,454,420 UniSTS RH 3.4 Map 2 673.4 UniSTS Cytogenetic Map 2 q25 UniSTS
RH139923
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 119,499,847 - 119,500,049 (+) MAPPER mRatBN7.2 Rnor_6.0 2 123,348,489 - 123,348,690 NCBI Rnor6.0 Rnor_5.0 2 142,963,844 - 142,964,045 UniSTS Rnor5.0 RGSC_v3.4 2 123,136,001 - 123,136,202 UniSTS RGSC3.4 Celera 2 114,457,934 - 114,458,135 UniSTS RH 3.4 Map 2 676.5 UniSTS Cytogenetic Map 2 q25 UniSTS
This gene Trpc3 is modified in the following models/strains:
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
64
63
32
25
32
6
191
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000046700 ⟹ ENSRNOP00000046270
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 119,481,400 - 119,547,707 (-) Ensembl Rnor_6.0 Ensembl 2 123,330,041 - 123,396,386 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000079004 ⟹ ENSRNOP00000071693
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 119,481,400 - 119,529,783 (-) Ensembl Rnor_6.0 Ensembl 2 123,330,705 - 123,396,147 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000080207 ⟹ ENSRNOP00000075444
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 119,481,400 - 119,558,855 (-) Ensembl Rnor_6.0 Ensembl 2 123,329,875 - 123,407,496 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000109104 ⟹ ENSRNOP00000095733
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 2 119,481,400 - 119,547,707 (-) Ensembl
RefSeq Acc Id:
NM_001415005 ⟹ NP_001401934
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 121,409,436 - 121,475,823 (-) NCBI mRatBN7.2 2 119,481,313 - 119,547,704 (-) NCBI
RefSeq Acc Id:
XM_008760941 ⟹ XP_008759163
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 121,409,436 - 121,475,847 (-) NCBI mRatBN7.2 2 119,481,313 - 119,547,750 (-) NCBI Rnor_6.0 2 123,329,954 - 123,396,403 (-) NCBI
Sequence:
AGGGAAACCGCGCCGTCTCGCCGCGATGCTGTCGGACCGGCAGACCACGCACAGCCGGCATCGCGGCCGCGGACCCCGAGCTCCGCTGCAGGTCGCGCGCTCGGCCCGGGCGGCCCCGGCGCCGCGGC
hide sequence
RefSeq Acc Id:
XM_039103014 ⟹ XP_038958942
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 121,409,436 - 121,475,847 (-) NCBI mRatBN7.2 2 119,481,313 - 119,547,750 (-) NCBI
RefSeq Acc Id:
XM_039103015 ⟹ XP_038958943
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 121,409,436 - 121,487,095 (-) NCBI mRatBN7.2 2 119,481,313 - 119,558,823 (-) NCBI
RefSeq Acc Id:
XM_063282439 ⟹ XP_063138509
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 2 121,434,312 - 121,475,849 (-) NCBI
RefSeq Acc Id:
XP_008759163 ⟸ XM_008760941
- Peptide Label:
isoform X2
- UniProtKB:
A0A0G2KAL8 (UniProtKB/TrEMBL)
- Sequence:
MSTKVKKCREPARVTLPAPEEEDGEAEGAEPQRRRRGWRGVNGGLEPPCPRAPPSPGPDASSEGSPSRWRTAGMRDKGRRQAVRGPAFMFGARGPSLTAEEERFLDAAEYGNIPVVRKMLEESRTLNV
hide sequence
Ensembl Acc Id:
ENSRNOP00000071693 ⟸ ENSRNOT00000079004
Ensembl Acc Id:
ENSRNOP00000075444 ⟸ ENSRNOT00000080207
Ensembl Acc Id:
ENSRNOP00000046270 ⟸ ENSRNOT00000046700
RefSeq Acc Id:
XP_038958943 ⟸ XM_039103015
- Peptide Label:
isoform X3
- UniProtKB:
A0A0G2KAL8 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038958942 ⟸ XM_039103014
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2KAL8 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000095733 ⟸ ENSRNOT00000109104
RefSeq Acc Id:
NP_001401934 ⟸ NM_001415005
- UniProtKB:
Q9JMI9 (UniProtKB/Swiss-Prot), F1LNQ7 (UniProtKB/Swiss-Prot), A0A0G2KAL8 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063138509 ⟸ XM_063282439
- Peptide Label:
isoform X4
RGD ID: 13691293 Promoter ID: EPDNEW_R1818 Type: single initiation site Name: Trpc3_1 Description: transient receptor potential cation channel, subfamily C, member3 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 2 123,396,362 - 123,396,422 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2004-09-10
Trpc3
transient receptor potential cation channel, subfamily C, member 3
transient receptor protein 3
Name updated
1299863 APPROVED
2002-06-10
Trpc3
transient receptor protein 3
Name updated
70584 APPROVED
2001-12-06
Trpc3
transient receptor protein 3
Symbol updated to reflect Human and Mouse nomenclature
69665 APPROVED
Note Type
Note
Reference
gene_transcript
alternatively spliced form of a rat Trp3 exists which is designated Trp3sv
61774
