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Gene: Trpc3 (transient receptor potential cation channel, subfamily C, member 3) Mus musculus
Symbol: Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
RGD ID: 62266
Description: Predicted to have calcium activated cation channel activity; inositol 1,4,5 trisphosphate binding activity; and store-operated calcium channel activity. Predicted to be involved in several processes, including metal ion transport; positive regulation of cardiac muscle hypertrophy in response to stress; and response to ATP. Predicted to localize to cation channel complex and integral component of plasma membrane. Is expressed in cochlea; ganglia; limb; spinal cord; and trunk somite. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3); INTERACTS WITH 17beta-estradiol; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC124333; mTrp3; Mwk; receptor-activated cation channel TRP3; short transient receptor potential channel 3; Tr; transient receptor protein 3; Trc; Trcp3; TRP-3; trp-related protein 3; Trp3; Trrp3
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl336,620,482 - 36,690,167 (-)EnsemblGRCm38mm10GRCm38
GRCm38336,620,482 - 36,690,429 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37336,519,404 - 36,589,089 (-)NCBIGRCm37mm9NCBIm37
MGSCv36336,812,122 - 36,863,152 (-)NCBImm8
Celera336,505,427 - 36,575,273 (-)NCBICelera
Cytogenetic Map3BNCBI
cM Map317.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Trpc3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62266
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.