Cdca8 (cell division cycle associated 8) - Rat Genome Database

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Gene: Cdca8 (cell division cycle associated 8) Rattus norvegicus
Analyze
Symbol: Cdca8
Name: cell division cycle associated 8
RGD ID: 1566306
Description: Predicted to be involved in mitotic metaphase chromosome alignment. Predicted to be located in several cellular components, including chromocenter; midbody; and nuclear lumen. Predicted to be part of chromosome passenger complex. Predicted to be active in chromosome, centromeric region and spindle midzone. Orthologous to human CDCA8 (cell division cycle associated 8); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: borealin; cell division cycle-associated protein 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85142,461,082 - 142,483,336 (-)NCBIGRCr8
mRatBN7.25137,176,414 - 137,198,686 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5137,176,417 - 137,198,629 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5139,879,673 - 139,902,403 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05141,649,678 - 141,672,408 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05141,656,859 - 141,679,587 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05142,911,310 - 142,933,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5142,911,305 - 142,933,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05146,680,981 - 146,700,067 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45144,251,164 - 144,276,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5135,697,190 - 135,716,709 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8RatCOVID-19  ISOCDCA8 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Cdca8Rathepatocellular carcinoma disease_progressionISOCDCA8 (Homo sapiens)153344586mRNA:increased expression:liver (human)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8RatCharcot-Marie-Tooth disease dominant intermediate C  ISOCDCA8 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate CClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8Rathepatocellular carcinoma  ISOCDCA8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560

1 to 20 of 169 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8Rat(1->4)-beta-D-glucan multiple interactionsISOCdca8 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CDCA8 mRNACTDPMID:36331819
Cdca8Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expressionISOCDCA8 (Homo sapiens)6480464o and p'-DDT results in decreased expression of CDCA8 mRNACTDPMID:18204070
Cdca8Rat1,1-dichloroethene increases expressionISOCdca8 (Mus musculus)6480464vinylidene chloride results in increased expression of CDCA8 mRNACTDPMID:26682919
Cdca8Rat1,2-dichloroethane decreases expressionISOCdca8 (Mus musculus)6480464ethylene dichloride results in decreased expression of CDCA8 mRNACTDPMID:28960355
Cdca8Rat1,2-dimethylhydrazine multiple interactionsISOCdca8 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDCA8 mRNACTDPMID:22206623
Cdca8Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of CDCA8 mRNACTDPMID:30723492
Cdca8Rat17alpha-ethynylestradiol increases expressionISOCdca8 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CDCA8 mRNACTDPMID:17942748
Cdca8Rat17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of CDCA8 mRNACTDPMID:17351261
Cdca8Rat17alpha-ethynylestradiol multiple interactionsISOCdca8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDCA8 mRNACTDPMID:17942748
Cdca8Rat17beta-estradiol increases expressionISOCdca8 (Mus musculus)6480464Estradiol results in increased expression of CDCA8 mRNACTDPMID:25210133
Cdca8Rat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of CDCA8 mRNACTDPMID:32145629
Cdca8Rat17beta-estradiol increases expressionISOCDCA8 (Homo sapiens)6480464Estradiol results in increased expression of CDCA8 mRNACTDPMID:19167446
Cdca8Rat17beta-estradiol multiple interactionsISOCdca8 (Mus musculus)6480464ESR1 protein promotes the reaction [Estradiol results in increased expression of CDCA8 mRNA]CTDPMID:25210133
Cdca8Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOCdca8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Cdca8Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionEXP 64804642 more ...CTDPMID:27291303
Cdca8Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOCDCA8 (Homo sapiens)64804642 more ...CTDPMID:31173147
Cdca8Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOCdca8 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Cdca8Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCdca8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDCA8 mRNA and AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDCA8 mRNA]CTDPMID:15034205 and PMID:17942748
Cdca8Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CDCA8 mRNACTDPMID:34747641
Cdca8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCdca8 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of CDCA8 mRNACTDPMID:15034205

1 to 20 of 169 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Cdca8Ratchromosome organization involved_inISOCDCA8 (Homo sapiens)1624291 PMID:15260989RGDPMID:15260989
Cdca8Ratchromosome organization involved_inIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratmitotic metaphase chromosome alignment involved_inISOCDCA8 (Homo sapiens)1624291 PMID:15260989RGDPMID:15260989
Cdca8Ratmitotic metaphase chromosome alignment involved_inIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratmitotic sister chromatid segregation involved_inIBAFB:FBgn0032105 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component
1 to 20 of 32 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8Ratchromocenter located_inISOCdca8 (Mus musculus)1624291 PMID:19283064RGDPMID:19283064
Cdca8Ratchromocenter located_inIEAUniProtKB:Q8BHX3 and ensembl:ENSMUSP000000813191600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratchromosome located_inIEAUniProtKB-KW:KW-01581600115GO_REF:0000043UniProtGO_REF:0000043
Cdca8Ratchromosome passenger complex part_ofISOCDCA8 (Homo sapiens)1624291UniProtKB:O15392 more ...RGDPMID:15260989 more ...
Cdca8Ratchromosome passenger complex part_ofIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratchromosome passenger complex part_ofIBAFB:FBgn0032104 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdca8Ratchromosome passenger complex part_ofISSUniProtKB:Q53HL21600115GO_REF:0000024UniProtGO_REF:0000024
Cdca8Ratchromosome, centromeric region located_inISOCDCA8 (Homo sapiens)1624291 PMID:15260989RGDPMID:15260989
Cdca8Ratchromosome, centromeric region located_inIEAUniProtKB-SubCell:SL-00471600115GO_REF:0000044UniProtGO_REF:0000044
Cdca8Ratchromosome, centromeric region is_active_inIBAFB:FBgn0032104 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdca8Ratchromosome, centromeric region located_inIEAUniProtKB-KW:KW-01371600115GO_REF:0000043UniProtGO_REF:0000043
Cdca8Ratchromosome, centromeric region located_inIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Cdca8Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Cdca8Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Cdca8Ratintercellular bridge located_inIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratintercellular bridge located_inISOCDCA8 (Homo sapiens)1624291 RGDGO_REF:0000052
Cdca8Ratmicrotubule cytoskeleton located_inISOCDCA8 (Homo sapiens)1624291 PMID:9859993RGDPMID:9859993
Cdca8Ratmicrotubule cytoskeleton located_inIEAUniProtKB:Q53HL2 and ensembl:ENSP000003621461600115GO_REF:0000107EnsemblGO_REF:0000107
Cdca8Ratmidbody located_inISOCDCA8 (Homo sapiens)1624291 PMID:22724069RGDPMID:22724069
1 to 20 of 32 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cdca8Ratprotein binding enablesISOCDCA8 (Homo sapiens)1624291UniProtKB:E7CU85 more ...RGDPMID:16239925 more ...
Cdca8Ratprotein binding enablesISOCdca8 (Mus musculus)1624291PR:O70201 PMID:17881355RGDPMID:17881355


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
5. Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm. Wang T, etal., Front Immunol. 2022 May 27;13:843408. doi: 10.3389/fimmu.2022.843408. eCollection 2022.
PMID:15260989   PMID:15489334   PMID:16239925   PMID:18591255   PMID:19283064   PMID:22724069  



Cdca8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85142,461,082 - 142,483,336 (-)NCBIGRCr8
mRatBN7.25137,176,414 - 137,198,686 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5137,176,417 - 137,198,629 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5139,879,673 - 139,902,403 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05141,649,678 - 141,672,408 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05141,656,859 - 141,679,587 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05142,911,310 - 142,933,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5142,911,305 - 142,933,526 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05146,680,981 - 146,700,067 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45144,251,164 - 144,276,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5135,697,190 - 135,716,709 (-)NCBICelera
Cytogenetic Map5q36NCBI
CDCA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38137,692,516 - 37,709,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl137,692,481 - 37,709,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37138,158,188 - 38,175,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36137,930,746 - 37,947,978 (+)NCBINCBI36Build 36hg18NCBI36
Build 34137,827,251 - 37,844,482NCBI
Celera136,436,198 - 36,453,412 (+)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef136,275,336 - 36,292,634 (+)NCBIHuRef
CHM1_1138,274,230 - 38,291,508 (+)NCBICHM1_1
T2T-CHM13v2.0137,557,243 - 37,574,423 (+)NCBIT2T-CHM13v2.0
Cdca8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394124,812,258 - 124,830,710 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4124,812,258 - 124,833,104 (-)EnsemblGRCm39 Ensembl
GRCm384124,918,465 - 124,936,917 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4124,918,465 - 124,939,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv374124,595,709 - 124,614,161 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364124,420,769 - 124,439,207 (-)NCBIMGSCv36mm8
Celera4123,240,998 - 123,259,215 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.93NCBI
Cdca8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545215,486,452 - 15,499,867 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545215,486,515 - 15,501,838 (+)NCBIChiLan1.0ChiLan1.0
CDCA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,129,491 - 189,146,874 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,258,572 - 188,275,955 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,965,470 - 36,982,761 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1138,314,597 - 38,331,625 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl138,314,597 - 38,331,625 (+)Ensemblpanpan1.1panPan2
CDCA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,796,980 - 4,809,914 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,798,197 - 4,809,658 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,044,396 - 5,057,330 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,931,395 - 4,944,330 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,931,471 - 4,944,307 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,790,802 - 4,803,734 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,857,151 - 4,870,085 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,873,734 - 4,886,669 (-)NCBIUU_Cfam_GSD_1.0
Cdca8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505854,070,308 - 54,086,901 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647419,895,640 - 19,912,933 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647419,895,681 - 19,912,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDCA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl693,750,689 - 93,764,836 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1693,750,694 - 93,764,845 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CDCA8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12095,151,814 - 95,169,111 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2095,151,752 - 95,169,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603321,640,702 - 21,658,296 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdca8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476420,418,585 - 20,434,026 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476420,418,342 - 20,433,763 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Cdca8
64 total Variants

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:78
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000048293
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat

1 to 10 of 45 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000048293   ⟹   ENSRNOP00000043633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5137,176,417 - 137,198,629 (-)Ensembl
Rnor_6.0 Ensembl5142,911,305 - 142,933,526 (-)Ensembl
RefSeq Acc Id: NM_001025050   ⟹   NP_001020221
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85142,461,087 - 142,483,199 (-)NCBI
mRatBN7.25137,176,419 - 137,198,532 (-)NCBI
Rnor_6.05142,911,319 - 142,933,431 (-)NCBI
Rnor_5.05146,680,981 - 146,700,067 (-)NCBI
RGSC_v3.45144,251,164 - 144,276,352 (-)RGD
Celera5135,697,190 - 135,716,709 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764064   ⟹   XP_008762286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85142,461,082 - 142,483,336 (-)NCBI
mRatBN7.25137,176,414 - 137,198,686 (-)NCBI
Rnor_6.05142,911,310 - 142,933,536 (-)NCBI
Sequence:
Protein RefSeqs NP_001020221 (Get FASTA)   NCBI Sequence Viewer  
  XP_008762286 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79274 (Get FASTA)   NCBI Sequence Viewer  
  AAH79293 (Get FASTA)   NCBI Sequence Viewer  
  EDL80412 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043633
  ENSRNOP00000043633.4
GenBank Protein Q6AXW0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020221   ⟸   NM_001025050
- UniProtKB: Q6AXW0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008762286   ⟸   XM_008764064
- Peptide Label: isoform X1
- UniProtKB: Q6AXW0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043633   ⟸   ENSRNOT00000048293
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXW0-F1-model_v2 AlphaFold Q6AXW0 1-288 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694018
Promoter ID:EPDNEW_R4541
Type:multiple initiation site
Name:Cdca8_1
Description:cell division cycle associated 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05142,933,503 - 142,933,563EPDNEW


1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39942 BioCyc
Ensembl Genes ENSRNOG00000031431 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000048293 ENTREZGENE
  ENSRNOT00000048293.5 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.140.560 UniProtKB/Swiss-Prot
  6.10.250.1900 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134027 IMAGE-MGC_LOAD
  IMAGE:7134482 IMAGE-MGC_LOAD
InterPro Borealin_C UniProtKB/Swiss-Prot
  Borealin_N UniProtKB/Swiss-Prot
  Cell_div_borealin UniProtKB/Swiss-Prot
KEGG Report rno:500545 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94394 IMAGE-MGC_LOAD
  MGC:94429 IMAGE-MGC_LOAD
NCBI Gene 500545 ENTREZGENE
PANTHER AUSTRALIN, ISOFORM A-RELATED UniProtKB/Swiss-Prot
  BOREALIN UniProtKB/Swiss-Prot
Pfam Borealin UniProtKB/Swiss-Prot
  Nbl1_Borealin_N UniProtKB/Swiss-Prot
PhenoGen Cdca8 PhenoGen
RatGTEx ENSRNOG00000031431 RatGTEx
UniProt A6IS61_RAT UniProtKB/TrEMBL
  BOREA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-02-09 Cdca8  cell division cycle associated 8      Symbol and Name status set to provisional 70820 PROVISIONAL