Dtx3 (deltex E3 ubiquitin ligase 3) - Rat Genome Database

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Gene: Dtx3 (deltex E3 ubiquitin ligase 3) Rattus norvegicus
Analyze
Symbol: Dtx3
Name: deltex E3 ubiquitin ligase 3
RGD ID: 1566181
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deltex 3 homolog; deltex 3 homolog (Drosophila); deltex 3, E3 ubiquitin ligase; deltex homolog 3; deltex homolog 3 (Drosophila); LOC500847; probable E3 ubiquitin-protein ligase DTX3; protein deltex-3; RGD1566181; similar to Deltex3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,898,693 - 64,904,636 (-)NCBIGRCr8
mRatBN7.2763,013,769 - 63,018,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,013,371 - 63,018,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,903,070 - 64,907,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,105,474 - 67,110,135 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,906,542 - 66,911,203 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,476,737 - 70,482,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,476,729 - 70,481,796 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,654,378 - 70,660,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,145,276 - 67,149,937 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera760,155,333 - 60,160,117 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3Ratcataract 15 multiple types  ISODTX3 (Homo sapiens)8554872ClinVar Annotator: match by term: Cataract 15 multiple typesClinVarPMID:28492532
Dtx3RatCharcot-Marie-Tooth disease axonal type 2U  ISODTX3 (Homo sapiens)8554872ClinVar Annotator: match by term: CHARCOT-MARIE-TOOTH DISEASE more ...ClinVarPMID:28492532
Dtx3Ratfamilial melanoma  ISODTX3 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial melanomaClinVarPMID:28492532
Dtx3RatINTERSTITIAL LUNG AND LIVER DISEASE  ISODTX3 (Homo sapiens)8554872ClinVar Annotator: match by term: Interstitial lung and liver diseaseClinVarPMID:28492532
Dtx3Ratparaplegia  ISODTX3 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3RatBreast Neoplasms  ISODTX3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25151356

1 to 20 of 56 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3Rat1,2-dimethylhydrazine increases expressionISODtx3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of DTX3 mRNACTDPMID:22206623
Dtx3Rat17alpha-ethynylestradiol increases expressionISODtx3 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of DTX3 mRNACTDPMID:17942748
Dtx3Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of DTX3 mRNACTDPMID:29097150
Dtx3Rat17alpha-ethynylestradiol multiple interactionsISODtx3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DTX3 mRNACTDPMID:17942748
Dtx3Rat17beta-estradiol decreases expressionISODTX3 (Homo sapiens)6480464Estradiol results in decreased expression of DTX3 mRNACTDPMID:31614463
Dtx3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISODtx3 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in increased expression of DTX3 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DTX3 mRNACTDPMID:17942748 and PMID:19465110
Dtx3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of DTX3 mRNACTDPMID:34747641
Dtx3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISODTX3 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of DTX3 mRNACTDPMID:21296121
Dtx3Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of DTX3 mRNACTDPMID:36041667
Dtx3Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of DTX3 mRNACTDPMID:30047161
Dtx3Ratacrolein multiple interactionsISODTX3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of DTX3 mRNACTDPMID:32845096
Dtx3Rataflatoxin B1 decreases methylationISODTX3 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of DTX3 geneCTDPMID:27153756
Dtx3Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of DTX3 mRNACTDPMID:30047161
Dtx3Ratantirheumatic drug increases expressionISODTX3 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of DTX3 mRNACTDPMID:24449571
Dtx3Ratbenzo[a]pyrene increases methylationISODTX3 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of DTX3 promoterCTDPMID:27901495
Dtx3Ratbis(2-ethylhexyl) phthalate decreases expressionISODTX3 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of DTX3 mRNACTDPMID:31163220
Dtx3Ratbis(2-ethylhexyl) phthalate increases expressionISODtx3 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of DTX3 mRNACTDPMID:33754040
Dtx3Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of DTX3 mRNACTDPMID:25181051
Dtx3Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of DTX3 mRNACTDPMID:36041667
Dtx3Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of DTX3 mRNACTDPMID:34947998

1 to 20 of 56 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3RatNotch signaling pathway acts_upstream_of_or_withinISODtx3 (Mus musculus)1624291 PMID:11226752RGDPMID:11226752
Dtx3RatNotch signaling pathway involved_inIBAMGI:1352744 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dtx3RatNotch signaling pathway involved_inIEAInterPro:IPR0393981600115GO_REF:0000002InterProGO_REF:0000002
Dtx3Ratprotein ubiquitination involved_inIEAUniPathway:UPA001431600115GO_REF:0000041UniProtGO_REF:0000041
Dtx3Ratprotein ubiquitination involved_inIEAUniRule:UR0014267731600115GO_REF:0000104UniProtGO_REF:0000104
Dtx3Ratprotein ubiquitination involved_inIEAInterPro:IPR0393981600115GO_REF:0000002InterProGO_REF:0000002
Dtx3Ratprotein ubiquitination involved_inIBAFB:FBgn0000524 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Dtx3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Dtx3Ratcytoplasm located_inIEAUniRule:UR0014267731600115GO_REF:0000104UniProtGO_REF:0000104
Dtx3Ratnucleoplasm is_active_inIBAPANTHER:PTN000289912 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Dtx3Ratprotein binding enablesISODTX3 (Homo sapiens)1624291UniProtKB:O14933 more ...RGDPMID:19549727 more ...
Dtx3Ratprotein binding enablesISODtx3 (Mus musculus)1624291PR:Q8R3P2 PMID:11226752RGDPMID:11226752
Dtx3Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Dtx3Ratubiquitin protein ligase activity enablesIEAUniRule:UR0014267731600115GO_REF:0000104UniProtGO_REF:0000104
Dtx3Ratubiquitin protein ligase activity enablesIBAFB:FBgn0000524 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dtx3Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dtx3RatNotch signaling pathway   IEA 6907045 KEGGrno:04330

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11226752  



Dtx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,898,693 - 64,904,636 (-)NCBIGRCr8
mRatBN7.2763,013,769 - 63,018,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,013,371 - 63,018,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,903,070 - 64,907,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,105,474 - 67,110,135 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,906,542 - 66,911,203 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,476,737 - 70,482,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,476,729 - 70,481,796 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,654,378 - 70,660,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,145,276 - 67,149,937 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera760,155,333 - 60,160,117 (-)NCBICelera
Cytogenetic Map7q22NCBI
DTX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,604,824 - 57,609,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,604,622 - 57,609,804 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,998,607 - 58,003,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,284,871 - 56,289,850 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,284,870 - 56,289,850NCBI
Celera1257,654,419 - 57,659,398 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1255,036,290 - 55,041,268 (+)NCBIHuRef
CHM1_11257,966,420 - 57,971,399 (+)NCBICHM1_1
T2T-CHM13v2.01257,572,308 - 57,578,021 (+)NCBIT2T-CHM13v2.0
Dtx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,026,242 - 127,032,367 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,026,247 - 127,031,597 (-)EnsemblGRCm39 Ensembl
GRCm3810127,190,373 - 127,196,498 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,190,378 - 127,195,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,627,434 - 126,632,765 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,593,327 - 126,598,658 (-)NCBIMGSCv36mm8
Celera10129,583,408 - 129,588,773 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Dtx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,328,725 - 5,334,092 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,328,723 - 5,334,092 (+)NCBIChiLan1.0ChiLan1.0
DTX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,731,185 - 36,734,797 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,727,956 - 36,731,568 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,316,968 - 31,322,340 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,576,351 - 31,581,819 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,577,001 - 31,579,669 (-)Ensemblpanpan1.1panPan2
DTX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,684,394 - 1,687,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,683,410 - 1,686,814 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,745,460 - 1,750,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,691,642 - 1,696,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,691,625 - 1,696,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,669,425 - 1,674,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,911,185 - 1,916,104 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0102,036,415 - 2,041,352 (+)NCBIUU_Cfam_GSD_1.0
Dtx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,115,836 - 57,121,204 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,751,387 - 1,754,353 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,749,061 - 1,754,399 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,867,711 - 22,873,393 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,867,691 - 22,873,413 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,734,097 - 24,820,351 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,512,657 - 53,517,978 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,515,043 - 53,517,330 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,444,161 - 192,449,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,354,077 - 10,359,769 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,353,488 - 10,359,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Dtx3
10 total Variants

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:99
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000006815
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat

1 to 10 of 35 rows
RH137001  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,020,091 - 63,020,271 (+)MAPPERmRatBN7.2
Rnor_6.0770,484,032 - 70,484,211NCBIRnor6.0
Rnor_5.0770,661,276 - 70,661,455UniSTSRnor5.0
RGSC_v3.4767,151,552 - 67,151,731UniSTSRGSC3.4
Celera760,161,688 - 60,161,867UniSTS
Cytogenetic Map7q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000006815   ⟹   ENSRNOP00000006815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl770,477,135 - 70,481,796 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090057   ⟹   ENSRNOP00000070751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,013,371 - 63,018,522 (-)Ensembl
Rnor_6.0 Ensembl770,476,729 - 70,480,724 (-)Ensembl
RefSeq Acc Id: NM_001191989   ⟹   NP_001178918
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,899,091 - 64,903,752 (-)NCBI
mRatBN7.2763,013,769 - 63,018,431 (-)NCBI
Rnor_6.0770,477,135 - 70,481,796 (-)NCBI
Rnor_5.0770,654,378 - 70,660,222 (-)NCBI
Celera760,155,333 - 60,160,117 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063264107   ⟹   XP_063120177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,904,635 (-)NCBI
RefSeq Acc Id: XM_063264108   ⟹   XP_063120178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,904,636 (-)NCBI
RefSeq Acc Id: XM_063264109   ⟹   XP_063120179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,904,631 (-)NCBI
RefSeq Acc Id: XM_063264110   ⟹   XP_063120180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,904,626 (-)NCBI
RefSeq Acc Id: XM_063264111   ⟹   XP_063120181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,903,685 (-)NCBI
RefSeq Acc Id: XM_063264112   ⟹   XP_063120182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,898,693 - 64,904,627 (-)NCBI
RefSeq Acc Id: NP_001178918   ⟸   NM_001191989
- UniProtKB: F1LY78 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070751   ⟸   ENSRNOT00000090057
Ensembl Acc Id: ENSRNOP00000006815   ⟸   ENSRNOT00000006815
RefSeq Acc Id: XP_063120178   ⟸   XM_063264108
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120177   ⟸   XM_063264107
- Peptide Label: isoform X1
RING-type

Name Modeler Protein Id AA Range Protein Structure
AF-F1LY78-F1-model_v2 AlphaFold F1LY78 1-347 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695252
Promoter ID:EPDNEW_R5777
Type:multiple initiation site
Name:Dtx3_1
Description:deltex E3 ubiquitin ligase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0770,481,810 - 70,481,870EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-33759 BioCyc
Ensembl Genes ENSRNOG00000005129 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090057 ENTREZGENE
  ENSRNOT00000090057.2 UniProtKB/TrEMBL
  ENSRNOT00000159022 ENTREZGENE
Gene3D-CATH 3.30.390.130 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro Deltex_C UniProtKB/TrEMBL
  Deltex_C_sf UniProtKB/TrEMBL
  Deltex_fam UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene 500847 ENTREZGENE
PANTHER PTHR12622 UniProtKB/TrEMBL
Pfam DTC UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/TrEMBL
PhenoGen Dtx3 PhenoGen
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005129 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A0G2JYQ5 ENTREZGENE, UniProtKB/TrEMBL
  F1LY78 ENTREZGENE
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Dtx3  deltex E3 ubiquitin ligase 3  Dtx3  deltex 3, E3 ubiquitin ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-02-06 Dtx3  deltex 3, E3 ubiquitin ligase  Dtx3  deltex homolog 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-03-24 Dtx3  deltex homolog 3 (Drosophila)  Dtx3  deltex 3 homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Dtx3  deltex 3 homolog (Drosophila)  RGD1566181_predicted  similar to Deltex3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566181_predicted  similar to Deltex3 (predicted)  LOC500847  similar to Deltex3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500847  similar to Deltex3      Symbol and Name status set to provisional 70820 PROVISIONAL