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Gene: Dtx3 (deltex 3, E3 ubiquitin ligase) Mus musculus
Symbol: Dtx3
Name: deltex 3, E3 ubiquitin ligase
Description: Predicted to have ubiquitin protein ligase activity. Involved in Notch signaling pathway. Predicted to localize to nucleoplasm. Is expressed in bladder; brain; ureter; and urethra of male. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deltex 3 homolog; Deltex3; mDTX3; mg310; MGC106339; probable E3 ubiquitin-protein ligase DTX3; protein deltex-3; RING-type E3 ubiquitin transferase DTX3
Homo sapiens (human) : DTX3 (deltex E3 ubiquitin ligase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dtx3 (deltex E3 ubiquitin ligase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dtx3 (deltex E3 ubiquitin ligase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DTX3 (deltex E3 ubiquitin ligase 3)
Canis lupus familiaris (dog) : DTX3 (deltex E3 ubiquitin ligase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dtx3 (deltex E3 ubiquitin ligase 3)
Sus scrofa (pig) : DTX3 (deltex E3 ubiquitin ligase 3)
Chlorocebus sabaeus (African green monkey) : DTX3 (deltex E3 ubiquitin ligase 3)
Heterocephalus glaber (naked mole-rat) : Dtx3 (deltex E3 ubiquitin ligase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10127,190,378 - 127,195,728 (-)EnsemblGRCm38mm10GRCm38
GRCm3810127,190,373 - 127,196,498 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,627,434 - 126,632,765 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610126,593,327 - 126,598,658 (-)NCBImm8
Celera10129,583,408 - 129,588,773 (-)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dtx3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557271
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.