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Gene: Dtx3 (deltex 3, E3 ubiquitin ligase) Mus musculus
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Symbol: Dtx3
Name: deltex 3, E3 ubiquitin ligase
Description: Predicted to have ubiquitin protein ligase activity. Involved in Notch signaling pathway. Predicted to localize to nucleoplasm. Is expressed in bladder; brain; ureter; and urethra of male. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deltex 3 homolog; Deltex3; mDTX3; mg310; MGC106339; probable E3 ubiquitin-protein ligase DTX3; protein deltex-3; RING-type E3 ubiquitin transferase DTX3
Orthologs:
Homo sapiens (human) : DTX3 (deltex E3 ubiquitin ligase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dtx3 (deltex E3 ubiquitin ligase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dtx3 (deltex E3 ubiquitin ligase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DTX3 (deltex E3 ubiquitin ligase 3)
Canis lupus familiaris (dog) : DTX3 (deltex E3 ubiquitin ligase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dtx3 (deltex E3 ubiquitin ligase 3)
Sus scrofa (pig) : DTX3 (deltex E3 ubiquitin ligase 3)
Chlorocebus sabaeus (African green monkey) : DTX3 (deltex E3 ubiquitin ligase 3)
Heterocephalus glaber (naked mole-rat) : Dtx3 (deltex E3 ubiquitin ligase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl10127,190,378 - 127,195,728 (-)EnsemblGRCm38mm10GRCm38
GRCm3810127,190,373 - 127,196,498 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,627,434 - 126,632,765 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610126,593,327 - 126,598,658 (-)NCBImm8
Celera10129,583,408 - 129,588,773 (-)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Dtx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557271
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.