Myot (myotilin) - Rat Genome Database

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Gene: Myot (myotilin) Rattus norvegicus
Analyze
Symbol: Myot
Name: myotilin
RGD ID: 1310569
Description: Predicted to enable alpha-actinin binding activity and cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Z disc. Predicted to be active in axon and plasma membrane. Human ortholog(s) of this gene implicated in muscular dystrophy and myofibrillar myopathy 3. Orthologous to human MYOT (myotilin); INTERACTS WITH acrylamide; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100909761; LOC291605; myotilin-like; titin immunoglobulin domain protein (myotilin); Ttid
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81836,956,119 - 36,975,728 (+)NCBIGRCr8
mRatBN7.21836,705,244 - 36,724,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1836,705,314 - 36,724,841 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1836,809,300 - 36,828,821 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01837,527,651 - 37,547,177 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01836,904,570 - 36,924,088 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01835,573,978 - 35,593,541 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,574,002 - 35,593,541 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl937,727,942 - 37,747,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01835,239,617 - 35,259,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,004,000 - 38,023,531 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map18q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRatmuscular dystrophy  ISOMYOT (Homo sapiens)1599673Limb-Girdle Muscular Dystrophy LGMD1A and OMIM:159000RGD 
1 to 14 of 14 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRatautosomal dominant intellectual developmental disorder 31  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: NEURODEVELOPMENTAL DISORDER WITH NEONATAL RESPIRATORY INSUFFICIENCY more ...ClinVarPMID:28492532
MyotRatcardiomyopathy  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: CardiomyopathyClinVarPMID:25741868 more ...
MyotRatcongestive heart failure  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Heart failureClinVarPMID:19240791 more ...
MyotRatfamilial adenomatous polyposis 1  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Familial adenomatous polyposis 1ClinVarPMID:17963004 more ...
MyotRatgenetic disease  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
MyotRatHereditary Neoplastic Syndromes  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary Cancer SyndromeClinVarPMID:18487285 more ...
MyotRatHereditary Neoplastic Syndromes  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary cancer-predisposing syndromeClinVarPMID:17963004 more ...
MyotRatlimb-girdle muscular dystrophy  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Limb-Girdle Muscular Dystrophy and DominantClinVarPMID:25741868 more ...
MyotRatMuscle Weakness  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Muscle weaknessClinVar 
MyotRatmyofibrillar myopathy  ISOMYOT (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15111675 more ...
MyotRatmyofibrillar myopathy 3  ISOMYOT (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10958653 more ...
MyotRatNeurodevelopmental Disorders  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
MyotRatprostate cancer  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:23265383
MyotRatSTING-associated vasculopathy with onset in infancy  ISOMYOT (Homo sapiens)8554872ClinVar Annotator: match by term: STING-associated vasculopathy with onset in infancyClinVarPMID:28492532
1 to 14 of 14 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRatatrial fibrillation  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:30061737
MyotRatcardiomyopathy  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15111675
MyotRatlimb-girdle muscular dystrophy  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21336781
MyotRatMuscle Weakness  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15111675
MyotRatmyofibrillar myopathy 3  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15111675
MyotRatperipheral nervous system disease  ISOMYOT (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15111675
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRatmyofibrillar myopathy 3  ISOMYOT (Homo sapiens)7240710 OMIM 

1 to 20 of 44 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRat17beta-estradiol decreases expressionISOMyot (Mus musculus)6480464Estradiol results in decreased expression of MYOT mRNACTDPMID:19484750
MyotRat17beta-estradiol multiple interactionsISOMYOT (Homo sapiens)6480464[Estradiol binds to ESR2 protein] which results in increased expression of MYOT mRNACTDPMID:20404318
MyotRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMyot (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MYOT mRNACTDPMID:21570461
MyotRat4,4'-sulfonyldiphenol decreases expressionISOMyot (Mus musculus)6480464bisphenol S results in decreased expression of MYOT mRNACTDPMID:30951980
MyotRat6-propyl-2-thiouracil multiple interactionsISOMyot (Mus musculus)6480464[Propylthiouracil co-treated with Iodine deficiency] results in increased expression of MYOT mRNACTDPMID:36706583
MyotRatacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of MYOT mRNACTDPMID:28959563
MyotRataflatoxin B1 decreases methylationISOMYOT (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of MYOT geneCTDPMID:27153756
MyotRataflatoxin B1 decreases expressionISOMYOT (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of MYOT mRNACTDPMID:32234424
MyotRatbenzo[a]pyrene increases expressionISOMYOT (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of MYOT mRNACTDPMID:22316170
MyotRatbenzo[a]pyrene increases methylationISOMyot (Mus musculus)6480464Benzo(a)pyrene results in increased methylation of MYOT exon and Benzo(a)pyrene results in increased methylation of MYOT intronCTDPMID:27901495
MyotRatbenzo[a]pyrene affects methylationISOMYOT (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of MYOT promoterCTDPMID:27901495
MyotRatbis(2-ethylhexyl) phthalate increases expressionISOMyot (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of MYOT mRNACTDPMID:28085963
MyotRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of MYOT mRNACTDPMID:25181051 and PMID:27178563
MyotRatbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of MYOT geneCTDPMID:28505145
MyotRatbisphenol F decreases expressionISOMyot (Mus musculus)6480464bisphenol F results in decreased expression of MYOT mRNACTDPMID:30951980
MyotRatbutanal increases expressionISOMYOT (Homo sapiens)6480464butyraldehyde results in increased expression of MYOT mRNACTDPMID:26079696
MyotRatCGP 52608 multiple interactionsISOMYOT (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to MYOT gene]CTDPMID:28238834
MyotRatdibutyl phthalate decreases expressionEXP 6480464Dibutyl Phthalate results in decreased expression of MYOT mRNACTDPMID:21266533
MyotRatdiiodine multiple interactionsISOMyot (Mus musculus)6480464[Propylthiouracil co-treated with Iodine deficiency] results in increased expression of MYOT mRNACTDPMID:36706583
MyotRatdimethylarsinic acid multiple interactionsISOMyot (Mus musculus)6480464[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of MYOT mRNACTDPMID:34876320

1 to 20 of 44 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRataxon guidance involved_inIBAFB:FBgn0000635 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MyotRatbiological_process  ND 15984072/2007: no relevant rat dataRGD 
MyotRatdendrite self-avoidance involved_inIBAFB:FBgn0010473 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MyotRathomophilic cell adhesion via plasma membrane adhesion molecules involved_inIBAFB:FBgn0000635 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MyotRataxon is_active_inIBAFB:FBgn0000635 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MyotRatplasma membrane is_active_inIBAFB:FBgn0000635 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MyotRatZ disc located_inISOMYOT (Homo sapiens)1624291 PMID:10958653RGDPMID:10958653
MyotRatZ disc located_inIEAUniProtKB:Q9JIF9 and ensembl:ENSMUSP000000253491600115GO_REF:0000107EnsemblGO_REF:0000107
MyotRatZ disc located_inISOMyot (Mus musculus)1624291 PMID:19047374RGDPMID:19047374
MyotRatZ disc part_ofISOMYOT (Homo sapiens)1624291 PMID:10958653RGDPMID:10958653

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Myotilin is mutated in limb girdle muscular dystrophy 1A. Hauser MA, etal., Hum Mol Genet. 2000 Sep 1;9(14):2141-7.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:19047374  



Myot
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81836,956,119 - 36,975,728 (+)NCBIGRCr8
mRatBN7.21836,705,244 - 36,724,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1836,705,314 - 36,724,841 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1836,809,300 - 36,828,821 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01837,527,651 - 37,547,177 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01836,904,570 - 36,924,088 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01835,573,978 - 35,593,541 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,574,002 - 35,593,541 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl937,727,942 - 37,747,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01835,239,617 - 35,259,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,004,000 - 38,023,531 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map18q11NCBI
MYOT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385137,867,860 - 137,887,851 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5137,867,858 - 137,887,851 (+)EnsemblGRCh38hg38GRCh38
GRCh375137,203,549 - 137,223,540 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365137,231,473 - 137,251,440 (+)NCBINCBI36Build 36hg18NCBI36
Build 345137,231,472 - 137,251,440NCBI
Celera5133,325,839 - 133,345,837 (+)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5132,395,358 - 132,415,358 (+)NCBIHuRef
CHM1_15136,636,150 - 136,656,170 (+)NCBICHM1_1
T2T-CHM13v2.05138,394,286 - 138,414,287 (+)NCBIT2T-CHM13v2.0
Myot
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391844,467,126 - 44,488,795 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1844,467,141 - 44,488,791 (+)EnsemblGRCm39 Ensembl
GRCm381844,334,053 - 44,355,740 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1844,334,074 - 44,355,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv371844,493,728 - 44,515,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361844,459,405 - 44,481,053 (+)NCBIMGSCv36mm8
Celera1845,713,780 - 45,735,414 (+)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1823.74NCBI
Myot
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540832,790,095 - 32,838,258 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540832,816,133 - 32,835,230 (+)NCBIChiLan1.0ChiLan1.0
MYOT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24133,143,300 - 133,170,336 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15131,282,853 - 131,309,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05133,254,644 - 133,274,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15139,386,101 - 139,411,960 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5139,386,101 - 139,411,960 (+)Ensemblpanpan1.1panPan2
MYOT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11125,574,087 - 25,592,767 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1125,564,136 - 25,592,339 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1124,338,045 - 24,356,731 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01126,424,036 - 26,442,735 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1126,424,113 - 26,442,730 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11125,131,713 - 25,150,406 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01124,955,437 - 24,974,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01125,618,123 - 25,636,808 (+)NCBIUU_Cfam_GSD_1.0
Myot
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213125,805,178 - 125,822,515 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365974,830,027 - 4,847,421 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365974,830,111 - 4,847,409 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2139,861,004 - 139,919,089 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12139,899,245 - 139,919,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22145,621,343 - 145,642,087 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYOT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12340,542,153 - 40,567,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2340,548,100 - 40,568,217 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603437,323,439 - 37,340,122 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myot
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247339,130,399 - 9,160,908 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247339,131,051 - 9,160,813 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Myot
66 total Variants

Predicted Target Of
Summary Value
Count of predictions:274
Count of miRNA genes:168
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000016511, ENSRNOT00000070817, ENSRNOT00000074276
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 43 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat

1 to 10 of 43 rows
RH131870  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01835,258,730 - 35,258,910NCBIRnor5.0
Rnor_5.0936,550,983 - 36,551,163NCBIRnor5.0
Rnor_5.01877,723,174 - 77,723,354NCBIRnor5.0
Rnor_5.01877,736,706 - 77,736,886NCBIRnor5.0
RGSC_v3.41838,023,106 - 38,023,285UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
5 12 9 20 18 22 6 5 6 6 50 28 10 3 14 16



Ensembl Acc Id: ENSRNOT00000070817   ⟹   ENSRNOP00000066839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1836,705,314 - 36,724,841 (+)Ensembl
Rnor_6.0 Ensembl1835,574,003 - 35,593,533 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093356   ⟹   ENSRNOP00000076325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,574,052 - 35,581,523 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093442   ⟹   ENSRNOP00000076167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,574,002 - 35,593,541 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,582,341 - 35,593,541 (+)Ensembl
RefSeq Acc Id: NM_001106148   ⟹   NP_001099618
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81836,956,191 - 36,975,722 (+)NCBI
mRatBN7.21836,705,314 - 36,724,841 (+)NCBI
Rnor_6.01835,574,003 - 35,593,533 (+)NCBI
Rnor_5.01835,239,617 - 35,259,164 (+)NCBI
RGSC_v3.41838,004,000 - 38,023,531 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254666   ⟹   XP_006254728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81836,956,119 - 36,975,728 (+)NCBI
mRatBN7.21836,705,244 - 36,724,849 (+)NCBI
Rnor_6.01835,573,978 - 35,593,539 (+)NCBI
Rnor_5.01835,239,617 - 35,259,164 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254667   ⟹   XP_006254729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81836,956,125 - 36,975,728 (+)NCBI
mRatBN7.21836,705,247 - 36,724,849 (+)NCBI
Rnor_6.01835,573,978 - 35,593,539 (+)NCBI
Rnor_5.01835,239,617 - 35,259,164 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254668   ⟹   XP_006254730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81836,956,119 - 36,975,728 (+)NCBI
mRatBN7.21836,705,244 - 36,724,849 (+)NCBI
Rnor_6.01835,573,979 - 35,593,541 (+)NCBI
Rnor_5.01835,239,617 - 35,259,164 (+)NCBI
Sequence:
Protein RefSeqs NP_001099618 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254728 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254729 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84754 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066839
  ENSRNOP00000066839.2
RefSeq Acc Id: NP_001099618   ⟸   NM_001106148
- UniProtKB: A6KUC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254729   ⟸   XM_006254667
- Peptide Label: isoform X1
- UniProtKB: M0RCF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254728   ⟸   XM_006254666
- Peptide Label: isoform X1
- UniProtKB: M0RCF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254730   ⟸   XM_006254668
- Peptide Label: isoform X2
- UniProtKB: A6KUC3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066839   ⟸   ENSRNOT00000070817
Ig-like

Name Modeler Protein Id AA Range Protein Structure
AF-M0RCF7-F1-model_v2 AlphaFold M0RCF7 1-497 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-7663 BioCyc
Ensembl Genes ENSRNOG00000047186 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000050004 Ensembl
Ensembl Transcript ENSRNOT00000070817 ENTREZGENE
  ENSRNOT00000070817.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
KEGG Report rno:291605 UniProtKB/TrEMBL
NCBI Gene 291605 ENTREZGENE
PANTHER BASIGIN RELATED UniProtKB/TrEMBL
  MYOTILIN UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
PhenoGen Myot PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047186 RatGTEx
  ENSRNOG00000050004 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A6KUC3 ENTREZGENE, UniProtKB/TrEMBL
  M0RCF7 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Myot  myotilin  LOC100909761  myotilin-like  Data merged from RGD:6502123 737654 PROVISIONAL
2012-07-05 LOC100909761  myotilin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Myot  myotilin   Myot_predicted  myotilin (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Myot_predicted  myotilin (predicted)  Ttid_predicted  titin immunoglobulin domain protein (myotilin) (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Ttid_predicted  titin immunoglobulin domain protein (myotilin) (predicted)      Symbol and Name status set to approved 70820 APPROVED