Rlbp1 (retinaldehyde binding protein 1) - Rat Genome Database

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Gene: Rlbp1 (retinaldehyde binding protein 1) Rattus norvegicus
Analyze
Symbol: Rlbp1
Name: retinaldehyde binding protein 1
RGD ID: 1309649
Description: Predicted to enable 11-cis retinal binding activity and phosphatidylinositol bisphosphate binding activity. Located in cell body. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to human RLBP1 (retinaldehyde binding protein 1); PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoid cycle metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293049; retinaldehyde-binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Arrd1
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,718,262 - 142,731,621 (-)NCBIGRCr8
mRatBN7.21133,308,920 - 133,322,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,308,938 - 133,322,296 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,217,953 - 141,231,346 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,387,376 - 148,400,769 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,305,075 - 141,318,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01141,097,789 - 141,111,375 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,097,695 - 141,111,400 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,059,882 - 142,073,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,122,063 - 135,135,420 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,201,061 - 135,219,115 (-)NCBI
Celera1125,372,094 - 125,385,448 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1Ratnight blindness  ISORLBP1 (Homo sapiens)1599620Fundus albipunctatus and OMIM:180090RGD 
Rlbp1Ratretinitis pigmentosa  ISORLBP1 (Homo sapiens)8547535 RGD 
Rlbp1Ratretinitis pigmentosa  ISORLBP1 (Homo sapiens)1599618bothnia dystrophy and OMIM:180090RGD 
1 to 17 of 17 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1RatAlpers-Huttenlocher syndrome  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive sclerosing poliodystrophyClinVarPMID:11301032 more ...
Rlbp1RatBloom syndrome  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:17407155 and PMID:28492532
Rlbp1RatBothnia retinal dystrophy  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratcolorectal cancer  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532
Rlbp1Ratcongenital stationary night blindness  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital stationary night blindnessClinVarPMID:25741868 more ...
Rlbp1RatD-2-hydroxyglutaric aciduria 2  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: D-2-hydroxyglutaric aciduria 2ClinVarPMID:17407155 and PMID:28492532
Rlbp1RatEye Abnormalities  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Abnormality of the eyeClinVarPMID:25326637 more ...
Rlbp1Ratfundus albipunctatus  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratfundus albipunctatus  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratfundus albipunctatus  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratfundus dystrophy  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Retinal dystrophyClinVarPMID:10102298 more ...
Rlbp1Ratgenetic disease  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Rlbp1RatNewfoundland cone-rod dystrophy  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Newfoundland cone-rod dystrophyClinVarPMID:10102298 more ...
Rlbp1Ratoptic atrophy  ISORLBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Optic atrophyClinVarPMID:25741868 and PMID:28492532
Rlbp1Ratretinitis pigmentosa  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratretinitis pigmentosa  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
Rlbp1Ratretinitis pigmentosa  ISORLBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10102298 more ...
1 to 17 of 17 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1RatBothnia retinal dystrophy  ISORLBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Rlbp1Ratfundus albipunctatus  ISORLBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Rlbp1RatHereditary Eye Diseases  ISORLBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16968212
Rlbp1Ratmacular degeneration  ISORLBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:30742112
Rlbp1RatNewfoundland cone-rod dystrophy  ISORLBP1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1RatBothnia retinal dystrophy  ISSRlbp1 (Mus musculus)13592920OMIM:607475MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1RatBothnia retinal dystrophy  ISORLBP1 (Homo sapiens)7240710 OMIM 
Rlbp1Ratfundus albipunctatus  ISORLBP1 (Homo sapiens)7240710 OMIM 
Rlbp1RatNewfoundland cone-rod dystrophy  ISORLBP1 (Homo sapiens)7240710 OMIM 

1 to 20 of 28 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1Rat(S)-nicotine increases expressionISORlbp1 (Mus musculus)6480464Nicotine results in increased expression of RLBP1 mRNACTDPMID:17997037
Rlbp1Rat17alpha-ethynylestradiol increases expressionISORlbp1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of RLBP1 mRNACTDPMID:17942748
Rlbp1Rat17alpha-ethynylestradiol affects expressionISORlbp1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of RLBP1 mRNACTDPMID:17555576
Rlbp1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORlbp1 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RLBP1 promoter]CTDPMID:19654925
Rlbp1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORlbp1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RLBP1 mRNACTDPMID:21570461
Rlbp1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of RLBP1 mRNACTDPMID:25825206
Rlbp1Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of RLBP1 mRNACTDPMID:38685447
Rlbp1Ratbenzo[a]pyrene affects methylationISORLBP1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of RLBP1 3' UTRCTDPMID:27901495
Rlbp1Ratbeta-lapachone increases expressionISORLBP1 (Homo sapiens)6480464beta-lapachone results in increased expression of RLBP1 mRNACTDPMID:38218311
Rlbp1Ratbis(2-ethylhexyl) phthalate decreases expressionISORLBP1 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of RLBP1 mRNACTDPMID:31163220
Rlbp1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of RLBP1 mRNACTDPMID:25181051
Rlbp1Ratbisphenol A decreases expressionISORlbp1 (Mus musculus)6480464bisphenol A results in decreased expression of RLBP1 mRNACTDPMID:32156529
Rlbp1Ratbisphenol A decreases methylationISORLBP1 (Homo sapiens)6480464bisphenol A results in decreased methylation of RLBP1 geneCTDPMID:31601247
Rlbp1Ratchlorpyrifos decreases expressionISORlbp1 (Mus musculus)6480464Chlorpyrifos results in decreased expression of RLBP1 mRNACTDPMID:37019170
Rlbp1RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of RLBP1 mRNACTDPMID:26577399
Rlbp1Ratdichloroacetic acid increases expressionISORlbp1 (Mus musculus)6480464Dichloroacetic Acid results in increased expression of RLBP1 mRNACTDPMID:28962523
Rlbp1Ratethanol affects expressionISORlbp1 (Mus musculus)6480464Ethanol affects the expression of RLBP1 mRNACTDPMID:30319688
Rlbp1Ratethanol increases expressionISORlbp1 (Mus musculus)6480464Ethanol results in increased expression of RLBP1 mRNACTDPMID:30319688
Rlbp1Ratethanol affects splicingISORlbp1 (Mus musculus)6480464Ethanol affects the splicing of RLBP1 mRNACTDPMID:30319688
Rlbp1Ratethylparaben decreases expressionISORLBP1 (Homo sapiens)6480464ethyl-p-hydroxybenzoate results in decreased expression of RLBP1 mRNACTDPMID:37690743

1 to 20 of 28 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1Ratbiological_process  ND 159840702/07: no relevant rat dataRGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rlbp1Ratcell body  IDA 6893662 RGD 
Rlbp1Ratcentrosome located_inIEAUniProtKB:P12271 and ensembl:ENSP000002681251600115GO_REF:0000107EnsemblGO_REF:0000107
Rlbp1Ratcentrosome located_inISORLBP1 (Homo sapiens)1624291 RGDGO_REF:0000052
Rlbp1Ratcytosol located_inIEAUniProtKB:P12271 and ensembl:ENSP000002681251600115GO_REF:0000107EnsemblGO_REF:0000107
Rlbp1Ratcytosol located_inISORLBP1 (Homo sapiens)1624291 RGDGO_REF:0000052
Rlbp1Ratnucleoplasm located_inIEAUniProtKB:P12271 and ensembl:ENSP000002681251600115GO_REF:0000107EnsemblGO_REF:0000107
Rlbp1Ratnucleoplasm located_inISORLBP1 (Homo sapiens)1624291 RGDGO_REF:0000052

Molecular Function

  

RGD Manual Annotations


  

1 to 13 of 13 rows
#
Reference Title
Reference Citation
1. Ocular phenotype of bothnia dystrophy, an autosomal recessive retinitis pigmentosa associated with an R234W mutation in the RLBP1 gene. Burstedt MS, etal., Arch Ophthalmol. 2001 Feb;119(2):260-7.
2. Genes and mutations causing retinitis pigmentosa. Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Localizations of visual cycle components in retinal pigment epithelium. Huang J, etal., Mol Vis. 2009;15:223-34. Epub 2009 Jan 26.
6. Fundus albipunctatus and retinitis punctata albescens in a pedigree with an R150Q mutation in RLBP1. Katsanis N, etal., Clin Genet. 2001 Jun;59(6):424-9.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision. von Lintig J, etal., Trends Biochem Sci. 2010 Jul;35(7):400-10. Epub 2010 Feb 24.
13. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait. Wright AF, etal., Nat Rev Genet. 2010 Apr;11(4):273-84. doi: 10.1038/nrg2717.
1 to 13 of 13 rows
PMID:9326942  



Rlbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,718,262 - 142,731,621 (-)NCBIGRCr8
mRatBN7.21133,308,920 - 133,322,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,308,938 - 133,322,296 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,217,953 - 141,231,346 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,387,376 - 148,400,769 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,305,075 - 141,318,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01141,097,789 - 141,111,375 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,097,695 - 141,111,400 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,059,882 - 142,073,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,122,063 - 135,135,420 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,201,061 - 135,219,115 (-)NCBI
Celera1125,372,094 - 125,385,448 (-)NCBICelera
Cytogenetic Map1q31NCBI
RLBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,209,869 - 89,221,579 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,209,869 - 89,221,614 (-)EnsemblGRCh38hg38GRCh38
GRCh371589,753,100 - 89,764,810 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,554,102 - 87,565,926 (-)NCBINCBI36Build 36hg18NCBI36
Build 341587,554,102 - 87,565,926NCBI
Celera1566,154,386 - 66,166,204 (-)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,865,051 - 65,876,811 (-)NCBIHuRef
CHM1_11589,594,080 - 89,605,905 (-)NCBICHM1_1
T2T-CHM13v2.01586,964,701 - 86,976,409 (-)NCBIT2T-CHM13v2.0
Rlbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,024,613 - 79,041,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,024,618 - 79,036,796 (-)EnsemblGRCm39 Ensembl
GRCm38779,374,865 - 79,392,250 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,374,870 - 79,387,048 (-)EnsemblGRCm38mm10GRCm38
MGSCv37786,519,756 - 86,531,913 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,248,384 - 79,258,298 (-)NCBIMGSCv36mm8
Celera776,771,983 - 76,784,152 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.0NCBI
Rlbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,862,426 - 15,873,327 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,862,510 - 15,873,261 (+)NCBIChiLan1.0ChiLan1.0
RLBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21678,756,312 - 78,769,640 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,460,801 - 82,474,300 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,901,276 - 67,913,911 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,108,815 - 87,117,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,108,815 - 87,117,971 (-)Ensemblpanpan1.1panPan2
RLBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,260,872 - 52,282,532 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,260,944 - 52,282,134 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,896,890 - 54,917,412 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,679,708 - 52,700,241 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,679,781 - 52,700,236 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,202,149 - 52,222,270 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,412,790 - 52,432,911 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,751,756 - 52,772,280 (-)NCBIUU_Cfam_GSD_1.0
Rlbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,236,419 - 131,247,998 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,084,756 - 15,096,072 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,086,485 - 15,097,980 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RLBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,776,113 - 54,889,014 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,783,965 - 54,800,008 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,759,346 - 59,775,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RLBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,756,742 - 7,769,061 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,757,158 - 7,765,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605939,059,553 - 39,071,474 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rlbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,406,925 - 16,421,385 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,410,328 - 16,423,722 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rlbp1
71 total Variants

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:83
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000022962
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 58 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat

1 to 10 of 58 rows
RH134202  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,309,023 - 133,309,231 (+)MAPPERmRatBN7.2
Rnor_6.01141,097,881 - 141,098,088NCBIRnor6.0
Rnor_5.01142,059,969 - 142,060,176UniSTSRnor5.0
RGSC_v3.41135,122,149 - 135,122,356UniSTSRGSC3.4
Celera1125,372,180 - 125,372,387UniSTS
RH 3.4 Map11060.8UniSTS
Cytogenetic Map1q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 43 113 76 75 45 25 45 6 189 88 93 39 60 30



Ensembl Acc Id: ENSRNOT00000022962   ⟹   ENSRNOP00000022962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,308,938 - 133,322,296 (-)Ensembl
Rnor_6.0 Ensembl1141,097,695 - 141,111,400 (-)Ensembl
RefSeq Acc Id: NM_001106274   ⟹   NP_001099744
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81142,718,262 - 142,731,621 (-)NCBI
mRatBN7.21133,308,937 - 133,322,296 (-)NCBI
Rnor_6.01141,097,795 - 141,111,375 (-)NCBI
Rnor_5.01142,059,882 - 142,073,463 (-)NCBI
RGSC_v3.41135,122,063 - 135,135,420 (-)RGD
Celera1125,372,094 - 125,385,448 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105632   ⟹   XP_038961560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81142,718,262 - 142,731,571 (-)NCBI
mRatBN7.21133,308,920 - 133,322,253 (-)NCBI
Protein RefSeqs NP_001099744 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961560 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM08575 (Get FASTA)   NCBI Sequence Viewer  
  EDM08576 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022962
  ENSRNOP00000022962.5
RefSeq Acc Id: NP_001099744   ⟸   NM_001106274
- UniProtKB: D3Z956 (UniProtKB/TrEMBL),   A6JC48 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022962   ⟸   ENSRNOT00000022962
RefSeq Acc Id: XP_038961560   ⟸   XM_039105632
- Peptide Label: isoform X1
CRAL-TRIO

Name Modeler Protein Id AA Range Protein Structure
AF-D3Z956-F1-model_v2 AlphaFold D3Z956 1-317 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-58808 BioCyc
BioCyc Pathway PWY-6861 [the visual cycle I (vertebrates)] BioCyc
BioCyc Pathway Image PWY-6861 BioCyc
Ensembl Genes ENSRNOG00000016897 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022962 ENTREZGENE
  ENSRNOT00000022962.7 UniProtKB/TrEMBL
Gene3D-CATH 3.40.525.10 UniProtKB/TrEMBL
  N-terminal domain of phosphatidylinositol transfer protein sec14p UniProtKB/TrEMBL
InterPro CRAL-bd_TRIO_C UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/TrEMBL
  Sec14p-like_N UniProtKB/TrEMBL
KEGG Report rno:293049 UniProtKB/TrEMBL
NCBI Gene 293049 ENTREZGENE
PANTHER ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR10174:SF200 UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/TrEMBL
  CRAL_TRIO_N UniProtKB/TrEMBL
PhenoGen Rlbp1 PhenoGen
PRINTS CRETINALDHBP UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016897 RatGTEx
SMART CRAL_TRIO_N UniProtKB/TrEMBL
  SEC14 UniProtKB/TrEMBL
Superfamily-SCOP CRAL_TRIO_C UniProtKB/TrEMBL
  Sec14p_like_N UniProtKB/TrEMBL
UniProt A6JC48 ENTREZGENE, UniProtKB/TrEMBL
  D3Z956 ENTREZGENE, UniProtKB/TrEMBL
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rlbp1  retinaldehyde binding protein 1   Rlbp1_predicted  retinaldehyde binding protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rlbp1_predicted  retinaldehyde binding protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED