Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8) - Rat Genome Database

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Gene: Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8) Rattus norvegicus
Analyze
Symbol: Ndufb8
Name: NADH:ubiquinone oxidoreductase subunit B8
RGD ID: 1309129
Description: Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Predicted to be active in mitochondrial inner membrane. Biomarker of acute kidney failure. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 32. Orthologous to human NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293991; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81253,357,878 - 253,362,936 (-)NCBIGRCr8
mRatBN7.21243,408,656 - 243,413,715 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,408,619 - 243,413,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1251,553,580 - 251,558,636 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01258,254,776 - 258,259,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,903,779 - 250,908,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01264,298,671 - 264,303,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,298,669 - 264,303,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,741,836 - 271,746,877 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,597,402 - 249,602,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,857,515 - 249,862,713 (-)NCBI
Celera1239,222,776 - 239,227,817 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8Ratgenetic disease  ISONDUFB8 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Ndufb8Ratnuclear type mitochondrial complex I deficiency 32  ISONDUFB8 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Ndufb8Ratrenal coloboma syndrome  ISONDUFB8 (Homo sapiens)8554872ClinVar Annotator: match by term: Renal coloboma syndromeClinVarPMID:11461952 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8RatArsenic Poisoning  ISONDUFB8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Ndufb8Ratskin disease  ISONDUFB8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16835338
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8Ratnuclear type mitochondrial complex I deficiency 32  ISONDUFB8 (Homo sapiens)7240710 OMIM 

1 to 20 of 124 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8Rat(+)-dexrazoxane decreases expressionISONdufb8 (Mus musculus)6480464Dexrazoxane results in decreased expression of NDUFB8 mRNACTDPMID:26873546
Ndufb8Rat(S)-nicotine decreases expressionEXP 6480464Nicotine results in decreased expression of NDUFB8 proteinCTDPMID:28681937
Ndufb8Rat1,2-dimethylhydrazine multiple interactionsISONdufb8 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NDUFB8 mRNACTDPMID:22206623
Ndufb8Rat1,2-dimethylhydrazine decreases expressionISONdufb8 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of NDUFB8 mRNACTDPMID:22206623
Ndufb8Rat17alpha-ethynylestradiol increases expressionISONdufb8 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of NDUFB8 mRNACTDPMID:17555576
Ndufb8Rat17alpha-ethynylestradiol multiple interactionsISONdufb8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NDUFB8 mRNACTDPMID:17942748
Ndufb8Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of NDUFB8 proteinCTDPMID:22070562
Ndufb8Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of NDUFB8 mRNACTDPMID:32145629
Ndufb8Rat17beta-estradiol decreases expressionISONdufb8 (Mus musculus)6480464Estradiol results in decreased expression of NDUFB8 mRNACTDPMID:19484750
Ndufb8Rat1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactionsISONDUFB8 (Homo sapiens)64804641H-(1 more ...CTDPMID:24041027
Ndufb8Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONdufb8 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NDUFB8 mRNACTDPMID:17942748
Ndufb8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NDUFB8 mRNACTDPMID:34747641
Ndufb8Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONdufb8 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NDUFB8 mRNACTDPMID:21570461
Ndufb8Rat3H-1,2-dithiole-3-thione increases expressionEXP 64804641 and 2-dithiol-3-thione results in increased expression of NDUFB8 mRNACTDPMID:19162173
Ndufb8Rat4,4'-sulfonyldiphenol increases expressionISONdufb8 (Mus musculus)6480464bisphenol S results in increased expression of NDUFB8 mRNACTDPMID:39298647
Ndufb8Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of NDUFB8 mRNACTDPMID:36041667
Ndufb8Rat5-aminolevulinic acid decreases expressionEXP 6480464Aminolevulinic Acid results in decreased expression of NDUFB8 proteinCTDPMID:18665889
Ndufb8Rat7,12-dimethyltetraphene increases expressionISONdufb8 (Mus musculus)64804649 more ...CTDPMID:38307155
Ndufb8Rat8-bromo-3',5'-cyclic GMP increases expressionISONDUFB8 (Homo sapiens)64804648-bromocyclic GMP results in increased expression of NDUFB8 proteinCTDPMID:24041027
Ndufb8Rat8-bromo-3',5'-cyclic GMP multiple interactionsISONDUFB8 (Homo sapiens)6480464tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NDUFB8 protein]CTDPMID:24041027

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8Ratbiological_process  ND 159840711/2018: no relevant rat dataRGD 
Ndufb8Ratmitochondrial electron transport, NADH to ubiquinone involved_inIEAUniRule:UR0001684571600115GO_REF:0000104UniProtGO_REF:0000104
Ndufb8Ratmitochondrial electron transport, NADH to ubiquinone involved_inIEAInterPro:IPR0165511600115GO_REF:0000002InterProGO_REF:0000002
Ndufb8Ratmitochondrial respiratory chain complex I assembly involved_inIEAUniRule:UR0001684571600115GO_REF:0000104UniProtGO_REF:0000104

Cellular Component
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Ndufb8Ratmitochondrial inner membrane is_active_inISONdufb8 (Mus musculus)1624291 PMID:38575788RGDPMID:38575788
Ndufb8Ratmitochondrial inner membrane located_inIEAUniProtKB:O95169 and ensembl:ENSP000002991661600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-01681600115GO_REF:0000044UniProtGO_REF:0000044
Ndufb8Ratmitochondrial inner membrane is_active_inIEAUniProtKB:Q9D6J5 and ensembl:ENSMUSP000000262221600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-09991600115GO_REF:0000043UniProtGO_REF:0000043
Ndufb8Ratmitochondrial inner membrane located_inISONDUFB8 (Homo sapiens)1624291 PMID:28844695RGDPMID:28844695
Ndufb8Ratmitochondrion located_inISONDUFB8 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Ndufb8Ratmitochondrion located_inIEAUniProtKB:O95169 and ensembl:ENSP000002991661600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Ndufb8Ratmitochondrion located_inISONdufb8 (Mus musculus)1624291 PMID:19837698RGDPMID:19837698
Ndufb8Ratmitochondrion located_inIEAUniProtKB:Q9D6J5 and ensembl:ENSMUSP000000262221600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratmitochondrion located_inIEAInterPro:IPR0086991600115GO_REF:0000002InterProGO_REF:0000002
Ndufb8Ratrespiratory chain complex I part_ofISONDUFB8 (Homo sapiens)1624291 PMID:12611891 more ...RGDPMID:12611891 more ...
Ndufb8Ratrespiratory chain complex I part_ofIEAUniRule:UR0001684571600115GO_REF:0000104UniProtGO_REF:0000104
Ndufb8Ratrespiratory chain complex I part_ofIEAUniProtKB:O95169 and ensembl:ENSP000002991661600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratrespiratory chain complex I part_ofIEAUniProtKB:Q9D6J5 and ensembl:ENSMUSP000000262221600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufb8Ratrespiratory chain complex I part_ofIBAFB:FBgn0029888 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ndufb8Ratrespiratory chain complex I part_ofISONdufb8 (Mus musculus)1624291 PMID:24154540 and PMID:38575788RGDPMID:24154540 and PMID:38575788
1 to 19 of 19 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufb8RatAlzheimer's disease pathway   IEA 6907045 KEGGrno:05010
Ndufb8RatHuntington's disease pathway   IEA 6907045 KEGGrno:05016
Ndufb8Ratoxidative phosphorylation pathway  IEA 6907045 KEGGrno:00190
Ndufb8RatParkinson's disease pathway   IEA 6907045 KEGGrno:05012

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#
Reference Title
Reference Citation
1. Persistent disruption of mitochondrial homeostasis after acute kidney injury. Funk JA and Schnellmann RG, Am J Physiol Renal Physiol. 2012 Apr 1;302(7):F853-64. doi: 10.1152/ajprenal.00035.2011. Epub 2011 Dec 7.
2. Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1a activation following ischemia-reperfusion injury. Funk JA and Schnellmann RG, Toxicol Appl Pharmacol. 2013 Dec 1;273(2):345-54. doi: 10.1016/j.taap.2013.09.026. Epub 2013 Oct 3.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Grünewald A, etal., Ann Neurol. 2016 Mar;79(3):366-78. doi: 10.1002/ana.24571. Epub 2016 Jan 28.
6. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
7. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Li YJ, etal., Hum Mol Genet 2003 Dec 15;12(24):3259-67. Epub 2003 Oct 21.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Sepsis-induced cardiac mitochondrial dysfunction involves altered mitochondrial-localization of tyrosine kinase Src and tyrosine phosphatase SHP2. Zang QS, etal., PLoS One. 2012;7(8):e43424. doi: 10.1371/journal.pone.0043424. Epub 2012 Aug 27.
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PMID:12477932   PMID:12611891   PMID:12865426   PMID:14651853   PMID:18614015   PMID:19393246   PMID:19837698   PMID:21700703   PMID:24154540   PMID:25002582   PMID:27626371   PMID:28844695  



Ndufb8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81253,357,878 - 253,362,936 (-)NCBIGRCr8
mRatBN7.21243,408,656 - 243,413,715 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1243,408,619 - 243,413,817 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1251,553,580 - 251,558,636 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01258,254,776 - 258,259,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01250,903,779 - 250,908,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01264,298,671 - 264,303,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,298,669 - 264,303,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,741,836 - 271,746,877 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,597,402 - 249,602,443 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,857,515 - 249,862,713 (-)NCBI
Celera1239,222,776 - 239,227,817 (-)NCBICelera
Cytogenetic Map1q54NCBI
NDUFB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810100,523,729 - 100,529,923 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10100,523,668 - 100,530,000 (-)EnsemblGRCh38hg38GRCh38
GRCh3710102,283,486 - 102,289,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610102,273,487 - 102,279,626 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410102,273,486 - 102,279,626NCBI
Celera1096,021,344 - 96,027,467 (-)NCBICelera
Cytogenetic Map10q24.31NCBI
HuRef1095,912,314 - 95,918,432 (-)NCBIHuRef
CHM1_110102,568,149 - 102,574,284 (-)NCBICHM1_1
T2T-CHM13v2.010101,406,832 - 101,413,008 (-)NCBIT2T-CHM13v2.0
Ndufb8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391944,537,010 - 44,543,881 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1944,537,011 - 44,543,879 (-)EnsemblGRCm39 Ensembl
GRCm381944,548,571 - 44,555,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1944,548,572 - 44,555,440 (-)EnsemblGRCm38mm10GRCm38
MGSCv371944,624,744 - 44,629,905 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361944,603,565 - 44,608,726 (-)NCBIMGSCv36mm8
Celera1945,317,871 - 45,323,032 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
Ndufb8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554859,607,781 - 9,613,151 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554859,607,781 - 9,613,123 (+)NCBIChiLan1.0ChiLan1.0
NDUFB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28112,407,560 - 112,419,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110112,412,880 - 112,425,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01097,123,826 - 97,129,919 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110100,604,914 - 100,611,016 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10100,604,914 - 100,611,016 (-)Ensemblpanpan1.1panPan2
NDUFB8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12813,249,067 - 13,253,670 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2813,249,070 - 13,253,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2813,420,026 - 13,424,630 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02813,718,281 - 13,722,885 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2813,717,817 - 13,722,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12813,264,760 - 13,269,366 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02813,306,376 - 13,310,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02813,437,377 - 13,441,981 (-)NCBIUU_Cfam_GSD_1.0
Ndufb8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721333,518,864 - 33,523,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366005,116,423 - 5,129,334 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366005,122,004 - 5,126,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFB8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14111,626,097 - 111,633,564 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114111,626,827 - 111,633,548 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2463,909,851 - 63,916,428 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFB8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1993,544,663 - 93,550,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl993,544,589 - 93,550,905 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604854,592,819 - 54,598,911 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufb8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624831191,625 - 200,860 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624831195,552 - 200,458 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ndufb8
15 total Variants

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000019039
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 62 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat

1 to 10 of 62 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000019039   ⟹   ENSRNOP00000019039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1243,408,659 - 243,413,817 (-)Ensembl
Rnor_6.0 Ensembl1264,298,669 - 264,303,762 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115908   ⟹   ENSRNOP00000086087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1243,408,619 - 243,413,704 (-)Ensembl
RefSeq Acc Id: NM_001106360   ⟹   NP_001099830
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81253,357,878 - 253,362,936 (-)NCBI
mRatBN7.21243,408,656 - 243,413,715 (-)NCBI
Rnor_6.01264,298,671 - 264,303,712 (-)NCBI
Rnor_5.01271,741,836 - 271,746,877 (-)NCBI
RGSC_v3.41249,597,402 - 249,602,443 (-)RGD
Celera1239,222,776 - 239,227,817 (-)RGD
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001099830 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66889 (Get FASTA)   NCBI Sequence Viewer  
  AAI66905 (Get FASTA)   NCBI Sequence Viewer  
  AAI66906 (Get FASTA)   NCBI Sequence Viewer  
  EDL94287 (Get FASTA)   NCBI Sequence Viewer  
  EDL94288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019039
  ENSRNOP00000019039.5
  ENSRNOP00000086087.1
1 to 9 of 9 rows
RefSeq Acc Id: NP_001099830   ⟸   NM_001106360
- UniProtKB: B2RYS8 (UniProtKB/TrEMBL),   A6JHG3 (UniProtKB/TrEMBL),   F7F9K9 (UniProtKB/TrEMBL),   B2RYU4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019039   ⟸   ENSRNOT00000019039
Ensembl Acc Id: ENSRNOP00000086087   ⟸   ENSRNOT00000115908

Name Modeler Protein Id AA Range Protein Structure
AF-B2RYS8-F1-model_v2 AlphaFold B2RYS8 1-186 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690940
Promoter ID:EPDNEW_R1465
Type:multiple initiation site
Name:Ndufb8_1
Description:NADH:ubiquinone oxidoreductase subunit B8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01264,303,733 - 264,303,793EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55585 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
Ensembl Genes ENSRNOG00000014078 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019039 ENTREZGENE
  ENSRNOT00000019039.8 UniProtKB/TrEMBL
  ENSRNOT00000115908.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887475 IMAGE-MGC_LOAD
  IMAGE:6888064 IMAGE-MGC_LOAD
  IMAGE:6891455 IMAGE-MGC_LOAD
InterPro NADH_UbQ_OxRdtase_ASHI_su UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_b-cplx_su8 UniProtKB/TrEMBL
KEGG Report rno:293991 UniProtKB/TrEMBL
MGC_CLONE MGC:188832 IMAGE-MGC_LOAD
  MGC:188870 IMAGE-MGC_LOAD
  MGC:188872 IMAGE-MGC_LOAD
NCBI Gene 293991 ENTREZGENE
PANTHER NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL UniProtKB/TrEMBL
  NDUFB8 UniProtKB/TrEMBL
Pfam NDUF_B8 UniProtKB/TrEMBL
PhenoGen Ndufb8 PhenoGen
PIRSF NDUB8 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014078 RatGTEx
UniProt A0A8I6A302_RAT UniProtKB/TrEMBL
  A6JHG3 ENTREZGENE
  B2RYS8 ENTREZGENE, UniProtKB/TrEMBL
  B2RYU4 ENTREZGENE, UniProtKB/TrEMBL
  F7F9K9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6JHG3 UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 Ndufb8  NADH:ubiquinone oxidoreductase subunit B8  Ndufb8  NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ndufb8  NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8   Ndufb8_predicted  NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ndufb8_predicted  NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED